메뉴 건너뛰기




Volumn 58, Issue 6, 2011, Pages 992-1004

The pathogenesis of IgA nephropathy: What is new and how does it change therapeutic approaches?

Author keywords

hypertension; Immunoglobulin A (IgA) nephropathy; mesangioproliferative glomerulonephritis; progression; proteinuria; recurrence

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GALACTOSE; IMMUNOGLOBULIN A1; IMMUNOGLOBULIN G ANTIBODY; OLIGODEOXYNUCLEOTIDE; PLATELET DERIVED GROWTH FACTOR; SPIRONOLACTONE; TOLL LIKE RECEPTOR 9;

EID: 81755171989     PISSN: 02726386     EISSN: 15236838     Source Type: Journal    
DOI: 10.1053/j.ajkd.2011.05.033     Document Type: Article
Times cited : (82)

References (176)
  • 2
    • 0038188539 scopus 로고    scopus 로고
    • Incidence of latent mesangial IgA deposition in renal allograft donors in Japan
    • DOI 10.1046/j.1523-1755.63.6s.2.x
    • K. Suzuki, K. Honda, K. Tanabe, H. Toma, H. Nihei, and Y. Yamaguchi Incidence of latent mesangial IgA deposition in renal allograft donors in Japan Kidney Int 63 6 2003 2286 2294 (Pubitemid 36605844)
    • (2003) Kidney International , vol.63 , Issue.6 , pp. 2286-2294
    • Suzuki, K.1    Honda, K.2    Tanabe, K.3    Toma, H.4    Nihei, H.5    Yamaguchi, Y.6
  • 3
    • 0035870771 scopus 로고    scopus 로고
    • The natural history of immunoglobulin A nephropathy among patients with hematuria and minimal proteinuria
    • C.C. Szeto, F.M. Lai, and K.F. To The natural history of immunoglobulin A nephropathy among patients with hematuria and minimal proteinuria Am J Med 110 6 2001 434 437
    • (2001) Am J Med , vol.110 , Issue.6 , pp. 434-437
    • Szeto, C.C.1    Lai, F.M.2    To, K.F.3
  • 4
    • 78650670905 scopus 로고    scopus 로고
    • Disappearance of glomerular IgA deposits in childhood IgA nephropathy showing diffuse mesangial proliferation after 2 years of combination/ prednisolone therapy
    • Y. Shima, K. Nakanishi, and K. Kamei Disappearance of glomerular IgA deposits in childhood IgA nephropathy showing diffuse mesangial proliferation after 2 years of combination/prednisolone therapy Nephrol Dial Transplant 26 1 2011 163 169
    • (2011) Nephrol Dial Transplant , vol.26 , Issue.1 , pp. 163-169
    • Shima, Y.1    Nakanishi, K.2    Kamei, K.3
  • 7
    • 2542491354 scopus 로고    scopus 로고
    • Recurrent IgA nephropathy after renal transplantation
    • DOI 10.1016/j.semnephrol.2004.01.008
    • J. Floege Recurrent IgA nephropathy after renal transplantation Semin Nephrol 24 3 2004 287 291 (Pubitemid 38685996)
    • (2004) Seminars in Nephrology , vol.24 , Issue.3 , pp. 287-291
    • Floege, J.1
  • 10
    • 26444513277 scopus 로고    scopus 로고
    • Renal protection in IgA nephropathy requires strict blood pressure control
    • DOI 10.1093/ndt/gfh920
    • J. Nagy, T. Kovacs, and I. Wittmann Renal protection in IgA nephropathy requires strict blood pressure control Nephrol Dial Transplant 20 8 2005 1533 1539 (Pubitemid 41418573)
    • (2005) Nephrology Dialysis Transplantation , vol.20 , Issue.8 , pp. 1533-1539
    • Nagy, J.1    Kovacs, T.2    Wittmann, I.3
  • 14
    • 0028848097 scopus 로고
    • Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy
    • H. Yoshida, T. Mitarai, and T. Kawamura Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy J Clin Invest 96 5 1995 2162 2169
    • (1995) J Clin Invest , vol.96 , Issue.5 , pp. 2162-2169
    • Yoshida, H.1    Mitarai, T.2    Kawamura, T.3
  • 15
    • 0030815913 scopus 로고    scopus 로고
    • Deletion insertion polymorphism of the angiotensin converting enzyme gene and progression of diabetic nephropathy
    • DOI 10.1093/ndt/12.1.67
    • S. Bjorck, G. Blohme, C. Sylven, and H. Mulec Deletion insertion polymorphism of the angiotensin converting enzyme gene and progression of diabetic nephropathy Nephrol Dial Transplant 12 suppl 2 1997 67 70 (Pubitemid 27331309)
    • (1997) Nephrology Dialysis Transplantation , vol.12 , Issue.SUPPL. 2 , pp. 67-70
    • Bjorck, S.1    Blohme, G.2    Sylven, C.3    Mulec, H.4
  • 17
    • 0031934284 scopus 로고    scopus 로고
    • Angiotensin-converting-enzyme insertion/deletion genotype and long-term renal allograft survival
    • DOI 10.1093/ndt/13.3.735
    • J. Beige, G. Offermann, A. Distler, and A.M. Sharma Angiotensin- converting-enzyme insertion/deletion genotype and long-term renal allograft survival Nephrol Dial Transplant 13 3 1998 735 738 (Pubitemid 28119061)
    • (1998) Nephrology Dialysis Transplantation , vol.13 , Issue.3 , pp. 735-738
    • Beige, J.1    Offermann, G.2    Distler, A.3    Sharma, A.M.4
  • 18
    • 0028785328 scopus 로고
    • No association of converting enzyme insertion/deletion polymorphism with immunoglobulin A glomerulonephritis
    • S. Schmidt, E. Stier, and R. Hartung No association of converting enzyme insertion/deletion polymorphism with immunoglobulin A glomerulonephritis Am J Kidney Dis 26 5 1995 727 731
    • (1995) Am J Kidney Dis , vol.26 , Issue.5 , pp. 727-731
    • Schmidt, S.1    Stier, E.2    Hartung, R.3
  • 21
    • 40849104187 scopus 로고    scopus 로고
    • Association of functional haem oxygenase-1 gene promoter polymorphism with polycystic kidney disease and IgA nephropathy
    • DOI 10.1093/ndt/gfm736
    • A.E. Courtney, P.T. McNamee, S. Heggarty, D. Middleton, and A.P. Maxwell Association of functional haem oxygenase-1 gene promoter polymorphism with polycystic kidney disease and IgA nephropathy Nephrol Dial Transplant 23 2 2008 608 611 (Pubitemid 351767643)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.2 , pp. 608-611
    • Courtney, A.E.1    McNamee, P.T.2    Heggarty, S.3    Middleton, D.4    Maxwell, A.P.5
  • 22
    • 0037384094 scopus 로고    scopus 로고
    • Polymorphisms of the tumour necrosis factor α gene at position - 308 and TNFd microsatellite in primary IgA nephropathy
    • DOI 10.1093/ndt/gfg010
    • S. Tuglular, P. Berthoux, and F. Berthoux Polymorphisms of the tumour necrosis factor alpha gene at position -308 and TNFd microsatellite in primary IgA nephropathy Nephrol Dial Transplant 18 4 2003 724 731 (Pubitemid 36432254)
    • (2003) Nephrology Dialysis Transplantation , vol.18 , Issue.4 , pp. 724-731
    • Tuglular, S.1    Berthoux, P.2    Berthoux, F.3
  • 23
    • 70349484209 scopus 로고    scopus 로고
    • Genetic variation in the transforming growth factor-beta1 gene is associated with susceptibility to IgA nephropathy
    • M.T. Vuong, S. Lundberg, and I. Gunnarsson Genetic variation in the transforming growth factor-beta1 gene is associated with susceptibility to IgA nephropathy Nephrol Dial Transplant 24 10 2009 3061 3067
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.10 , pp. 3061-3067
    • Vuong, M.T.1    Lundberg, S.2    Gunnarsson, I.3
  • 24
    • 0033624584 scopus 로고    scopus 로고
    • Alleles of the alpha1 immunoglobulin gene 3′ enhancer control evolution of IgA nephropathy toward renal failure
    • C. Aupetit, M. Drouet, and E. Pinaud Alleles of the alpha1 immunoglobulin gene 3′ enhancer control evolution of IgA nephropathy toward renal failure Kidney Int 58 3 2000 966 971
    • (2000) Kidney Int , vol.58 , Issue.3 , pp. 966-971
    • Aupetit, C.1    Drouet, M.2    Pinaud, E.3
  • 27
    • 0036222515 scopus 로고    scopus 로고
    • Controversies concerning the importance of genetic polymorphism in IgA nephropathy
    • L. Frimat, and M. Kessler Controversies concerning the importance of genetic polymorphism in IgA nephropathy Nephrol Dial Transplant 17 4 2002 542 545 (Pubitemid 34308803)
    • (2002) Nephrology Dialysis Transplantation , vol.17 , Issue.4 , pp. 542-545
    • Frimat, L.1    Kessler, M.2
  • 29
    • 31544442195 scopus 로고    scopus 로고
    • CC-chemokine receptor five gene polymorphism in primary IgA nephropathy: The 32 bp deletion allele is associated with late progression to end-stage renal failure with dialysis
    • DOI 10.1038/sj.ki.5000106, PII 5000106
    • F.C. Berthoux, P. Berthoux, C. Mariat, L. Thibaudin, A. Afiani, and M.T. Linossier CC-chemokine receptor five gene polymorphism in primary IgA nephropathy: the 32 bp deletion allele is associated with late progression to end-stage renal failure with dialysis Kidney Int 69 3 2006 565 572 (Pubitemid 43164451)
    • (2006) Kidney International , vol.69 , Issue.3 , pp. 565-572
    • Berthoux, F.C.1    Berthoux, P.2    Mariat, C.3    Thibaudin, L.4    Afiani, A.5    Linossier, M.-T.6
  • 31
    • 77957886047 scopus 로고    scopus 로고
    • HLA has strongest association with IgA nephropathy in genome-wide analysis
    • J. Feehally, M. Farrall, and A. Boland HLA has strongest association with IgA nephropathy in genome-wide analysis J Am Soc Nephrol 21 10 2010 1791 1797
    • (2010) J Am Soc Nephrol , vol.21 , Issue.10 , pp. 1791-1797
    • Feehally, J.1    Farrall, M.2    Boland, A.3
  • 32
    • 79953224410 scopus 로고    scopus 로고
    • Genome-wide association study identifies susceptibility loci for IgA nephropathy
    • A. Gharavi, K. Kiryluk, and M. Choi Genome-wide association study identifies susceptibility loci for IgA nephropathy Nat Genet 43 4 2011 321 327
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 321-327
    • Gharavi, A.1    Kiryluk, K.2    Choi, M.3
  • 33
    • 0033762699 scopus 로고    scopus 로고
    • IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23
    • A.G. Gharavi, Y. Yan, and F. Scolari IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23 Nat Genet 26 3 2000 354 357
    • (2000) Nat Genet , vol.26 , Issue.3 , pp. 354-357
    • Gharavi, A.G.1    Yan, Y.2    Scolari, F.3
  • 37
    • 44049087515 scopus 로고    scopus 로고
    • IL5RA and TNFRSF6B gene variants are associated with sporadic IgA nephropathy
    • X.Q. Liu, A.D. Paterson, and N. He IL5RA and TNFRSF6B gene variants are associated with sporadic IgA nephropathy J Am Soc Nephrol 19 5 2008 1025 1033
    • (2008) J Am Soc Nephrol , vol.19 , Issue.5 , pp. 1025-1033
    • Liu, X.Q.1    Paterson, A.D.2    He, N.3
  • 38
    • 0042861342 scopus 로고    scopus 로고
    • Hypothesis: Dysregulation of immunologic balance resulting from hygiene and socioeconomic factors may influence the epidemiology and cause of glomerulonephritis worldwide
    • DOI 10.1016/S0272-6386(03)00801-1
    • R.J. Johnson, A. Hurtado, J. Merszei, B. Rodriguez-Iturbe, and L. Feng Hypothesis: dysregulation of immunologic balance resulting from hygiene and socioeconomic factors may influence the epidemiology and cause of glomerulonephritis worldwide Am J Kidney Dis 42 3 2003 575 581 (Pubitemid 37048135)
    • (2003) American Journal of Kidney Diseases , vol.42 , Issue.3 , pp. 575-581
    • Johnson, R.J.1    Hurtado, A.2    Merszei, J.3    Rodriguez-Iturbe, B.4    Feng, L.5
  • 40
    • 78649447662 scopus 로고    scopus 로고
    • Spontaneous remission of IgA nephropathy associated with resolution of hepatitis A
    • S.H. Han, E.W. Kang, and J.H. Kie Spontaneous remission of IgA nephropathy associated with resolution of hepatitis A Am J Kidney Dis 56 6 2010 1163 1167
    • (2010) Am J Kidney Dis , vol.56 , Issue.6 , pp. 1163-1167
    • Han, S.H.1    Kang, E.W.2    Kie, J.H.3
  • 42
    • 57149101578 scopus 로고    scopus 로고
    • Toll-like receptor 9 affects severity of IgA nephropathy
    • H. Suzuki, Y. Suzuki, and I. Narita Toll-like receptor 9 affects severity of IgA nephropathy J Am Soc Nephrol 19 12 2008 2384 2395
    • (2008) J Am Soc Nephrol , vol.19 , Issue.12 , pp. 2384-2395
    • Suzuki, H.1    Suzuki, Y.2    Narita, I.3
  • 44
    • 70749091638 scopus 로고    scopus 로고
    • Toll-like receptor 4 expression is increased in circulating mononuclear cells of patients with immunoglobulin A nephropathy
    • R. Coppo, R. Camilla, and A. Amore Toll-like receptor 4 expression is increased in circulating mononuclear cells of patients with immunoglobulin A nephropathy Clin Exp Immunol 159 1 2010 73 81
    • (2010) Clin Exp Immunol , vol.159 , Issue.1 , pp. 73-81
    • Coppo, R.1    Camilla, R.2    Amore, A.3
  • 45
    • 44449113162 scopus 로고    scopus 로고
    • External suppression causes the low expression of the Cosmc gene in IgA nephropathy
    • DOI 10.1093/ndt/gfm781
    • W. Qin, X. Zhong, J.M. Fan, Y.J. Zhang, X.R. Liu, and X.Y. Ma External suppression causes the low expression of the Cosmc gene in IgA nephropathy Nephrol Dial Transplant 23 5 2008 1608 1614 (Pubitemid 351767729)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.5 , pp. 1608-1614
    • Qin, W.1    Zhong, X.2    Fan, J.M.3    Zhang, Y.J.4    Liu, X.R.5    Ma, X.Y.6
  • 46
    • 77953684865 scopus 로고    scopus 로고
    • Innate immune receptors and autophagy: Implications for autoimmune kidney injury
    • H.J. Anders, and D.O. Schlondorff Innate immune receptors and autophagy: implications for autoimmune kidney injury Kidney Int 78 1 2010 29 37
    • (2010) Kidney Int , vol.78 , Issue.1 , pp. 29-37
    • Anders, H.J.1    Schlondorff, D.O.2
  • 48
    • 0025007135 scopus 로고
    • The structure and function of human IgA
    • M.A. Kerr The structure and function of human IgA Biochem J 271 2 1990 285 296 (Pubitemid 20344737)
    • (1990) Biochemical Journal , vol.271 , Issue.2 , pp. 285-296
    • Kerr, M.A.1
  • 49
    • 31144457922 scopus 로고    scopus 로고
    • The function of immunoglobulin A in immunity
    • DOI 10.1002/path.1877
    • J.M. Woof, and M.A. Kerr The function of immunoglobulin A in immunity J Pathol 208 2 2006 270 282 (Pubitemid 43126119)
    • (2006) Journal of Pathology , vol.208 , Issue.2 , pp. 270-282
    • Woof, J.M.1    Ken, M.A.2
  • 51
    • 0032818068 scopus 로고    scopus 로고
    • Elevation of serum IgA in spondyloarthropathies and IgA nephropathy and its pathogenic role
    • DOI 10.1097/00002281-199907000-00007
    • V. Montenegro, and R.C. Monteiro Elevation of serum IgA in spondyloarthropathies and IgA nephropathy and its pathogenic role Curr Opin Rheumatol 11 4 1999 265 272 (Pubitemid 29383856)
    • (1999) Current Opinion in Rheumatology , vol.11 , Issue.4 , pp. 265-272
    • Montenegro, V.1    Monteiro, R.C.2
  • 54
    • 0030051001 scopus 로고    scopus 로고
    • Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation for J chain mRNA
    • S.J. Harper, A.C. Allen, J.H. Pringle, and J. Feehally Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation for J chain mRNA J Clin Pathol 49 1 1996 38 42 (Pubitemid 26037051)
    • (1996) Journal of Clinical Pathology , vol.49 , Issue.1 , pp. 38-42
    • Harper, S.J.1    Allen, A.C.2    Pringle, J.H.3    Feehally, J.4
  • 55
    • 42949166703 scopus 로고    scopus 로고
    • B-cell O-galactosyltransferase activity, and expression of O-glycosylation genes in bone marrow in IgA nephropathy
    • DOI 10.1038/sj.ki.5002748, PII 5002748
    • K.S. Buck, A.C. Smith, K. Molyneux, H. El-Barbary, J. Feehally, and J. Barratt B-cell O-galactosyltransferase activity, and expression of O-glycosylation genes in bone marrow in IgA nephropathy Kidney Int 73 10 2008 1128 1136 (Pubitemid 351620426)
    • (2008) Kidney International , vol.73 , Issue.10 , pp. 1128-1136
    • Buck, K.S.1    Smith, A.C.2    Molyneux, K.3    El-Barbary, H.4    Feehally, J.5    Barratt, J.6
  • 56
    • 77951695933 scopus 로고    scopus 로고
    • Glomerulonephritis after hematopoietic cell transplantation: IgA nephropathy with increased excretion of galactose-deficient IgA1
    • S.L. Hu, G.A. Colvin, and A. Rifai Glomerulonephritis after hematopoietic cell transplantation: IgA nephropathy with increased excretion of galactose-deficient IgA1 Nephrol Dial Transplant 25 5 2010 1708 1713
    • (2010) Nephrol Dial Transplant , vol.25 , Issue.5 , pp. 1708-1713
    • Hu, S.L.1    Colvin, G.A.2    Rifai, A.3
  • 63
    • 77954783577 scopus 로고    scopus 로고
    • Influence of tonsillectomy on the progression of mesangioproliferative glomerulonephritis
    • A. Piccoli, M. Codognotto, M.G. Tabbi, E. Favaro, and B. Rossi Influence of tonsillectomy on the progression of mesangioproliferative glomerulonephritis Nephrol Dial Transplant 25 8 2010 2583 2589
    • (2010) Nephrol Dial Transplant , vol.25 , Issue.8 , pp. 2583-2589
    • Piccoli, A.1    Codognotto, M.2    Tabbi, M.G.3    Favaro, E.4    Rossi, B.5
  • 64
    • 0033011425 scopus 로고    scopus 로고
    • Tonsillectomy does not prevent a progressive course in IgA nephropathy
    • F.M. Rasche, A. Schwarz, and F. Keller Tonsillectomy does not prevent a progressive course in IgA nephropathy Clin Nephrol 51 3 1999 147 152 (Pubitemid 29116416)
    • (1999) Clinical Nephrology , vol.51 , Issue.3 , pp. 147-152
    • Rasche, F.M.1    Schwarz, A.2    Keller, F.3
  • 66
    • 34548262721 scopus 로고    scopus 로고
    • Irreversible aggregation of the Fc fragment derived from polymeric but not monomeric serum IgA1-Implications in IgA-mediated disease
    • DOI 10.1016/j.molimm.2007.05.002, PII S0161589007002179
    • A. Almogren, and M.A. Kerr Irreversible aggregation of the Fc fragment derived from polymeric but not monomeric serum IgA1implications in IgA-mediated disease Mol Immunol 45 1 2008 87 94 (Pubitemid 47331651)
    • (2008) Molecular Immunology , vol.45 , Issue.1 , pp. 87-94
    • Almogren, A.1    Kerr, M.A.2
  • 67
    • 5444221231 scopus 로고    scopus 로고
    • An increased polymeric IgA level is not a prognostic marker for progressive IgA nephropathy
    • P.J. van der Boog, C. van Kooten, and A. van Seggelen An increased polymeric IgA level is not a prognostic marker for progressive IgA nephropathy Nephrol Dial Transplant 19 10 2004 2487 2493
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.10 , pp. 2487-2493
    • Van Der Boog, P.J.1    Van Kooten, C.2    Van Seggelen, A.3
  • 68
    • 0022877397 scopus 로고
    • Sequential study of the IgA system in relapsing IgA nephropathy
    • J. Feehally, T.J. Beattie, P.E. Brenchley, B.M. Coupes, N.P. Mallick, and R.J. Postlethwaite Sequential study of the IgA system in relapsing IgA nephropathy Kidney Int 30 6 1986 924 931 (Pubitemid 17055720)
    • (1986) Kidney International , vol.30 , Issue.6 , pp. 924-931
    • Feehally, J.1    Beattie, T.J.2    Brenchley, P.E.C.3
  • 70
    • 44449084054 scopus 로고    scopus 로고
    • The level of serum secretory IgA of patients with IgA nephropathy is elevated and associated with pathological phenotypes
    • DOI 10.1093/ndt/gfm492
    • J.J. Zhang, L.X. Xu, G. Liu, M.H. Zhao, and H.Y. Wang The level of serum secretory IgA of patients with IgA nephropathy is elevated and associated with pathological phenotypes Nephrol Dial Transplant 23 1 2008 207 212 (Pubitemid 351767351)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.1 , pp. 207-212
    • Zhang, J.-J.1    Xu, L.-X.2    Liu, G.3    Zhao, M.-H.4    Wang, H.-Y.5
  • 71
    • 33645515736 scopus 로고    scopus 로고
    • A pathogenic role for secretory IgA in IgA nephropathy
    • B.D. Oortwijn, P.J. van der Boog, and A. Roos A pathogenic role for secretory IgA in IgA nephropathy Kidney Int 69 7 2006 1131 1138
    • (2006) Kidney Int , vol.69 , Issue.7 , pp. 1131-1138
    • Oortwijn, B.D.1    Van Der Boog, P.J.2    Roos, A.3
  • 73
    • 0029001438 scopus 로고
    • Galactosylation of N- and O-linked carbohydrate moieties of IgA1 and IgG in IgA nephropathy
    • A.C. Allen, S.J. Harper, and J. Feehally Galactosylation of N- and O-linked carbohydrate moieties of IgA1 and IgG in IgA nephropathy Clin Exp Immunol 100 3 1995 470 474
    • (1995) Clin Exp Immunol , vol.100 , Issue.3 , pp. 470-474
    • Allen, A.C.1    Harper, S.J.2    Feehally, J.3
  • 77
    • 0035723058 scopus 로고    scopus 로고
    • Mesangial Iga1 in IgA nephropathy exhibits aberrant O-glycosylation: Observations in three patients
    • DOI 10.1046/j.1523-1755.2001.060003969.x
    • A.C. Allen, E.M. Bailey, P.E. Brenchley, K.S. Buck, J. Barratt, and J. Feehally Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: observations in three patients Kidney Int 60 3 2001 969 973 (Pubitemid 34205796)
    • (2001) Kidney International , vol.60 , Issue.3 , pp. 969-973
    • Allen, A.C.1    Bailey, E.M.2    Brenchley, P.E.C.3    Buck, K.S.4    Barratt, J.5    Feehally, J.6
  • 78
    • 28344453175 scopus 로고    scopus 로고
    • The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy
    • DOI 10.1111/j.1365-2249.2005.02949.x
    • L.X. Xu, Y. Yan, J.J. Zhang, Y. Zhang, and M.H. Zhao The glycans deficiencies of macromolecular IgA1 is a contributory factor of variable pathological phenotypes of IgA nephropathy Clin Exp Immunol 142 3 2005 569 575 (Pubitemid 41719854)
    • (2005) Clinical and Experimental Immunology , vol.142 , Issue.3 , pp. 569-575
    • Xu, L.-X.1    Yan, Y.2    Zhang, J.-J.3    Zhang, Y.4    Zhao, M.-H.5
  • 79
    • 24944496919 scopus 로고    scopus 로고
    • Aberrantly glycosylated serum IgA1 are closely associated with pathologic phenotypes of IgA nephropathy
    • L.X. Xu, and M.H. Zhao Aberrantly glycosylated serum IgA1 are closely associated with pathologic phenotypes of IgA nephropathy Kidney Int 68 1 2005 167 172
    • (2005) Kidney Int , vol.68 , Issue.1 , pp. 167-172
    • Xu, L.X.1    Zhao, M.H.2
  • 80
    • 0031925983 scopus 로고    scopus 로고
    • Abnormal IgA glycosylation in Henoch-Schonlein purpura restricted to patients with clinical nephritis
    • DOI 10.1093/ndt/13.4.930
    • A.C. Allen, F.R. Willis, T.J. Beattie, and J. Feehally Abnormal IgA glycosylation in Henoch-Schonlein purpura restricted to patients with clinical nephritis Nephrol Dial Transplant 13 4 1998 930 934 (Pubitemid 28161766)
    • (1998) Nephrology Dialysis Transplantation , vol.13 , Issue.4 , pp. 930-934
    • Allen, A.C.1    Willis, F.R.2    Beattie, T.J.3    Feehally, J.4
  • 81
    • 0036150134 scopus 로고    scopus 로고
    • Enzymatically deglycosylated human IgA1 molecules accumulate and induce inflammatory cell reaction in rat glomeruli
    • T. Sano, Y. Hiki, T. Kokubo, H. Iwase, H. Shigematsu, and Y. Kobayashi Enzymatically deglycosylated human IgA1 molecules accumulate and induce inflammatory cell reaction in rat glomeruli Nephrol Dial Transplant 17 1 2002 50 56 (Pubitemid 34093009)
    • (2002) Nephrology Dialysis Transplantation , vol.17 , Issue.1 , pp. 50-56
    • Sano, T.1    Hiki, Y.2    Kokubo, T.3    Iwase, H.4    Shigematsu, H.5    Kobayashi, Y.6
  • 82
    • 0030894229 scopus 로고    scopus 로고
    • Leucocyte β1,3 galactosyltransferase activity in IgA nephropathy
    • DOI 10.1093/ndt/12.4.701
    • A.C. Allen, P.S. Topham, S.J. Harper, and J. Feehally Leucocyte beta 1,3 galactosyltransferase activity in IgA nephropathy Nephrol Dial Transplant 12 4 1997 701 706 (Pubitemid 27170423)
    • (1997) Nephrology Dialysis Transplantation , vol.12 , Issue.4 , pp. 701-706
    • Allen, A.C.1    Topham, P.S.2    Harper, S.J.3    Feehally, J.4
  • 85
    • 78649499628 scopus 로고    scopus 로고
    • Down-regulation of core 1 beta1,3-galactosyltransferase and Cosmc by Th2 cytokine alters O-glycosylation of IgA1
    • K. Yamada, N. Kobayashi, and T. Ikeda Down-regulation of core 1 beta1,3-galactosyltransferase and Cosmc by Th2 cytokine alters O-glycosylation of IgA1 Nephrol Dial Transplant 25 12 2010 3890 3897
    • (2010) Nephrol Dial Transplant , vol.25 , Issue.12 , pp. 3890-3897
    • Yamada, K.1    Kobayashi, N.2    Ikeda, T.3
  • 86
    • 73949134362 scopus 로고    scopus 로고
    • Aberrant galactosylation of IgA1 is involved in the genetic susceptibility of Chinese patients with IgA nephropathy
    • X. Lin, J. Ding, and L. Zhu Aberrant galactosylation of IgA1 is involved in the genetic susceptibility of Chinese patients with IgA nephropathy Nephrol Dial Transplant 24 11 2009 3372 3375
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.11 , pp. 3372-3375
    • Lin, X.1    Ding, J.2    Zhu, L.3
  • 87
    • 44049083282 scopus 로고    scopus 로고
    • Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy
    • A.G. Gharavi, Z. Moldoveanu, and R.J. Wyatt Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy J Am Soc Nephrol 19 5 2008 1008 1014
    • (2008) J Am Soc Nephrol , vol.19 , Issue.5 , pp. 1008-1014
    • Gharavi, A.G.1    Moldoveanu, Z.2    Wyatt, R.J.3
  • 88
    • 78149319893 scopus 로고    scopus 로고
    • Galactose-deficient IgA1 in African Americans with IgA nephropathy: Serum levels and heritability
    • M.C. Hastings, Z. Moldoveanu, and B.A. Julian Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability Clin J Am Soc Nephrol 5 11 2010 2069 2074
    • (2010) Clin J Am Soc Nephrol , vol.5 , Issue.11 , pp. 2069-2074
    • Hastings, M.C.1    Moldoveanu, Z.2    Julian, B.A.3
  • 89
    • 27644442375 scopus 로고    scopus 로고
    • Chaperone mutation in Tn syndrome
    • DOI 10.1038/4371252a, PII 4371252
    • T. Ju, and R.D. Cummings Protein glycosylation: chaperone mutation in Tn syndrome Nature 437 7063 2005 1252 (Pubitemid 41568663)
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1252
    • Ju, T.1    Cummings, R.D.2
  • 90
    • 58049209804 scopus 로고    scopus 로고
    • No evidence for a role of cosmc-chaperone mutations in European IgA nephropathy patients
    • F. Malycha, T. Eggermann, and M. Hristov No evidence for a role of cosmc-chaperone mutations in European IgA nephropathy patients Nephrol Dial Transplant 24 1 2009 321 324
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.1 , pp. 321-324
    • Malycha, F.1    Eggermann, T.2    Hristov, M.3
  • 91
    • 0033663064 scopus 로고    scopus 로고
    • IgA nephropathy: Recent developments
    • J. Floege, and J. Feehally IgA nephropathy: recent developments J Am Soc Nephrol 11 12 2000 2395 2403
    • (2000) J Am Soc Nephrol , vol.11 , Issue.12 , pp. 2395-2403
    • Floege, J.1    Feehally, J.2
  • 92
    • 0033048645 scopus 로고    scopus 로고
    • Expression of interferon-inducible Mx-proteins in patients with IgA nephropathy or Henoch-Schonlein purpura
    • J. Floege, M. Burg, A.N. Al Masri, H.J. Grone, and P. von Wussow Expression of interferon-inducible Mx-proteins in patients with IgA nephropathy or Henoch-Schonlein purpura Am J Kidney Dis 33 3 1999 434 440 (Pubitemid 29107019)
    • (1999) American Journal of Kidney Diseases , vol.33 , Issue.3 , pp. 434-440
    • Floege, J.1    Burg, M.2    Al Masri, A.N.3    Grone, H.J.4    Von Wussow, P.5
  • 94
    • 0032893726 scopus 로고    scopus 로고
    • Decreased IgA1 response after primary oral immunization with live typhoid vaccine in primary IgA nephropathy
    • DOI 10.1093/ndt/14.2.353
    • J.I. Roodnat, J.W. de Fijter, C. van Kooten, M.R. Daha, and L.A. van Es Decreased IgA1 response after primary oral immunization with live typhoid vaccine in primary IgA nephropathy Nephrol Dial Transplant 14 2 1999 353 359 (Pubitemid 29062790)
    • (1999) Nephrology Dialysis Transplantation , vol.14 , Issue.2 , pp. 353-359
    • Roodnat, J.I.1    De Fijter, J.W.2    Van Kooten, C.3    Daha, M.R.4    Van Es, L.A.5
  • 96
    • 60749098431 scopus 로고    scopus 로고
    • Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy
    • R. Coppo, R. Camilla, and A. Alfarano Upregulation of the immunoproteasome in peripheral blood mononuclear cells of patients with IgA nephropathy Kidney Int 75 5 2009 536 541
    • (2009) Kidney Int , vol.75 , Issue.5 , pp. 536-541
    • Coppo, R.1    Camilla, R.2    Alfarano, A.3
  • 97
    • 0025203509 scopus 로고
    • Defective oral tolerance promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization
    • L. Gesualdo, M.E. Lamm, and S.N. Emancipator Defective oral tolerance promotes nephritogenesis in experimental IgA nephropathy induced by oral immunization J Immunol 145 11 1990 3684 3691
    • (1990) J Immunol , vol.145 , Issue.11 , pp. 3684-3691
    • Gesualdo, L.1    Lamm, M.E.2    Emancipator, S.N.3
  • 101
    • 33845270782 scopus 로고    scopus 로고
    • O-glycosylation of serum IgA1 antibodies against mucosal and systemic antigens in IgA nephropathy
    • DOI 10.1681/ASN.2006060658
    • A.C. Smith, K. Molyneux, J. Feehally, and J. Barratt O-Glycosylation of serum IgA1 antibodies against mucosal and systemic antigens in IgA nephropathy J Am Soc Nephrol 17 12 2006 3520 3528 (Pubitemid 44865295)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.12 , pp. 3520-3528
    • Smith, A.C.1    Molyneux, K.2    Feehally, J.3    Barratt, J.4
  • 102
    • 71049118207 scopus 로고    scopus 로고
    • Immune complex formation in IgA nephropathy: A case of the 'right' antibodies in the 'wrong' place at the 'wrong' time?
    • J. Barratt, F. Eitner, J. Feehally, and J. Floege Immune complex formation in IgA nephropathy: a case of the 'right' antibodies in the 'wrong' place at the 'wrong' time? Nephrol Dial Transplant 24 12 2009 3620 3623
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.12 , pp. 3620-3623
    • Barratt, J.1    Eitner, F.2    Feehally, J.3    Floege, J.4
  • 104
    • 34249060980 scopus 로고    scopus 로고
    • Altered expression of lymphocyte homing chemokines in the pathogenesis of IgA nephropathy
    • M. Buren, M. Yamashita, Y. Suzuki, Y. Tomino, and S.N. Emancipator Altered expression of lymphocyte homing chemokines in the pathogenesis of IgA nephropathy Contrib Nephrol 157 2007 50 55
    • (2007) Contrib Nephrol , vol.157 , pp. 50-55
    • Buren, M.1    Yamashita, M.2    Suzuki, Y.3    Tomino, Y.4    Emancipator, S.N.5
  • 105
    • 84859747590 scopus 로고    scopus 로고
    • New treatment of IgA nephropathy: Enteric budesonide targeted to the ileocecal region ameliorates proteinuria [published online ahead of print March 4, 2011]
    • doi:10.1093/ndt/gfr052
    • Smerud HK, Barany P, Lindstrom K, et al. New treatment of IgA nephropathy: enteric budesonide targeted to the ileocecal region ameliorates proteinuria [published online ahead of print March 4, 2011]. Nephrol Dial Transplant. doi:10.1093/ndt/gfr052.
    • Nephrol Dial Transplant
    • Smerud, H.K.1    Barany, P.2    Lindstrom, K.3
  • 107
    • 0025837070 scopus 로고
    • Mesangial cell autoantigens in immunoglobulin A nephropathy and Henoch-Schonlein purpura
    • D.J. O'Donoghue, A. Darvill, and F.W. Ballardie Mesangial cell autoantigens in immunoglobulin A nephropathy and Henoch-Schonlein purpura J Clin Invest 88 5 1991 1522 1530
    • (1991) J Clin Invest , vol.88 , Issue.5 , pp. 1522-1530
    • O'Donoghue, D.J.1    Darvill, A.2    Ballardie, F.W.3
  • 110
    • 0032695357 scopus 로고    scopus 로고
    • Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies
    • M. Tomana, J. Novak, B.A. Julian, K. Matousovic, K. Konecny, and J. Mestecky Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies J Clin Invest 104 1 1999 73 81 (Pubitemid 29534347)
    • (1999) Journal of Clinical Investigation , vol.104 , Issue.1 , pp. 73-81
    • Tomana, M.1    Novak, J.2    Julian, B.A.3    Matousovic, K.4    Konecny, K.5    Mestecky, J.6
  • 111
    • 67651006853 scopus 로고    scopus 로고
    • Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity
    • H. Suzuki, R. Fan, and Z. Zhang Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity J Clin Invest 119 6 2009 1668 1677
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1668-1677
    • Suzuki, H.1    Fan, R.2    Zhang, Z.3
  • 112
    • 38349136846 scopus 로고    scopus 로고
    • IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy
    • J. Novak, B.A. Julian, M. Tomana, and J. Mestecky IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy Semin Nephrol 28 1 2008 78 87
    • (2008) Semin Nephrol , vol.28 , Issue.1 , pp. 78-87
    • Novak, J.1    Julian, B.A.2    Tomana, M.3    Mestecky, J.4
  • 113
    • 80053490773 scopus 로고    scopus 로고
    • Current therapy for IgA nephropathy
    • In press
    • J. Floege, and F. Eitner Current therapy for IgA nephropathy J Am Soc Nephrol 2011 In press
    • (2011) J Am Soc Nephrol
    • Floege, J.1    Eitner, F.2
  • 114
    • 0019979827 scopus 로고
    • Detection of polymeric IgA in glomeruli from patients with IgA nephropathy
    • Y. Tomino, H. Sakai, M. Miura, M. Endoh, and Y. Nomoto Detection of polymeric IgA in glomeruli from patients with IgA nephropathy Clin Exp Immunol 49 2 1982 419 425 (Pubitemid 12097372)
    • (1982) Clinical and Experimental Immunology , vol.49 , Issue.2 , pp. 419-425
    • Tomino, Y.1    Sakai, H.2    Miura, M.3
  • 116
    • 0035161794 scopus 로고    scopus 로고
    • 1 to human mesangial cells in IgA nephropathy
    • DOI 10.1046/j.1523-1755.2001.00489.x
    • J.C. Leung, S.C. Tang, M.F. Lam, T.M. Chan, and K.N. Lai Charge-dependent binding of polymeric IgA1 to human mesangial cells in IgA nephropathy Kidney Int 59 1 2001 277 285 (Pubitemid 32055236)
    • (2001) Kidney International , vol.59 , Issue.1 , pp. 277-285
    • Leung, J.C.K.1    Tang, S.C.W.2    Man Fai Lam3    Tak Mao Chan4    Kar Neng Lai5
  • 117
  • 118
    • 0030882005 scopus 로고    scopus 로고
    • Evidence for involvement of IgA1 hinge glycopeptide in the IgA1-IgA1 interaction in IgA nephropathy
    • T. Kokubo, Y. Hiki, and H. Iwase Evidence for involvement of IgA1 hinge glycopeptide in the IgA1-IgA1 interaction in IgA nephropathy J Am Soc Nephrol 8 6 1997 915 919
    • (1997) J Am Soc Nephrol , vol.8 , Issue.6 , pp. 915-919
    • Kokubo, T.1    Hiki, Y.2    Iwase, H.3
  • 120
    • 0036145758 scopus 로고    scopus 로고
    • Increased sialylation of polymeric lambda-IgA1 in patients with IgA nephropathy
    • J.C. Leung, S.C. Tang, D.T. Chan, S.L. Lui, and K.N. Lai Increased sialylation of polymeric lambda-IgA1 in patients with IgA nephropathy J Clin Lab Anal 16 1 2002 11 19
    • (2002) J Clin Lab Anal , vol.16 , Issue.1 , pp. 11-19
    • Leung, J.C.1    Tang, S.C.2    Chan, D.T.3    Lui, S.L.4    Lai, K.N.5
  • 121
    • 0034686416 scopus 로고    scopus 로고
    • The N-glycans determine the differential blood clearance and hepatic uptake of human immunoglobulin (Ig)A1 and IgA2 isotypes
    • A. Rifai, K. Fadden, S.L. Morrison, and K.R. Chintalacharuvu The N-glycans determine the differential blood clearance and hepatic uptake of human immunoglobulin (Ig)A1 and IgA2 isotypes J Exp Med 191 12 2000 2171 2182
    • (2000) J Exp Med , vol.191 , Issue.12 , pp. 2171-2182
    • Rifai, A.1    Fadden, K.2    Morrison, S.L.3    Chintalacharuvu, K.R.4
  • 122
    • 0030836018 scopus 로고    scopus 로고
    • Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG
    • M. Tomana, K. Matousovic, B.A. Julian, J. Radl, K. Konecny, and J. Mestecky Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG Kidney Int 52 2 1997 509 516 (Pubitemid 27359597)
    • (1997) Kidney International , vol.52 , Issue.2 , pp. 509-516
    • Tomana, M.1    Matousovic, K.2    Julian, B.A.3    Radl, J.4    Konecny, K.5    Mestecky, J.6
  • 123
    • 0020093749 scopus 로고
    • Disappearance of glomerular mesangial IgA deposits after renal allograft transplantation
    • F.G. Silva, P. Chander, C.L. Pirani, and M.A. Hardy Disappearance of glomerular mesangial IgA deposits after renal allograft transplantation Transplantation 33 2 1982 241 246
    • (1982) Transplantation , vol.33 , Issue.2 , pp. 241-246
    • Silva, F.G.1    Chander, P.2    Pirani, C.L.3    Hardy, M.A.4
  • 124
    • 0026843506 scopus 로고
    • Macromolecular properties that promote mesangial binding and mesangiopathic nephritis
    • S.N. Emancipator, C.S. Rao, A. Amore, R. Coppo, and J.G. Nedrud Macromolecular properties that promote mesangial binding and mesangiopathic nephritis J Am Soc Nephrol 2(10) suppl 2 1992 S149 S158
    • (1992) J Am Soc Nephrol , vol.210 , Issue.SUPPL. 2
    • Emancipator, S.N.1    Rao, C.S.2    Amore, A.3    Coppo, R.4    Nedrud, J.G.5
  • 126
    • 46849104686 scopus 로고    scopus 로고
    • Bacterial protease for the treatment of IgA nephropathy
    • DOI 10.1093/ndt/gfn155
    • F. Eitner, and J. Floege Bacterial protease for the treatment of IgA nephropathy Nephrol Dial Transplant 23 7 2008 2173 2175 (Pubitemid 351957626)
    • (2008) Nephrology Dialysis Transplantation , vol.23 , Issue.7 , pp. 2173-2175
    • Eitner, F.1    Floege, J.2
  • 130
    • 33644789446 scopus 로고    scopus 로고
    • Engagement of transferrin receptor by polymeric IgA1: Evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy
    • I.C. Moura, M. Arcos-Fajardo, and A. Gdoura Engagement of transferrin receptor by polymeric IgA1: evidence for a positive feedback loop involving increased receptor expression and mesangial cell proliferation in IgA nephropathy J Am Soc Nephrol 16 9 2005 2667 2676
    • (2005) J Am Soc Nephrol , vol.16 , Issue.9 , pp. 2667-2676
    • Moura, I.C.1    Arcos-Fajardo, M.2    Gdoura, A.3
  • 133
    • 0345516004 scopus 로고    scopus 로고
    • Mesangial cells possess an asialoglycoprotein receptor with affinity for human immunoglobulin A
    • C. Gomez-Guerrero, N. Duque, and J. Egido Mesangial cells possess an asialoglycoprotein receptor with affinity for human immunoglobulin A J Am Soc Nephrol 9 4 1998 568 576 (Pubitemid 28186044)
    • (1998) Journal of the American Society of Nephrology , vol.9 , Issue.4 , pp. 568-576
    • Gomez-Guerrero, C.1    Duque, N.2    Egido, J.3
  • 134
    • 0031706337 scopus 로고    scopus 로고
    • IgA induced activation of human mesangial cells: Independent of FcαR1 (CD 89)
    • DOI 10.1046/j.1523-1755.1998.00054.x
    • S.C. Diven, C.R. Caflisch, D.K. Hammond, P.H. Weigel, J.A. Oka, and R.M. Goldblum IgA induced activation of human mesangial cells: independent of FcalphaR1 (CD 89) Kidney Int 54 3 1998 837 847 (Pubitemid 28397401)
    • (1998) Kidney International , vol.54 , Issue.3 , pp. 837-847
    • Diven, S.C.1    Caflisch, C.R.2    Hammond, D.K.3    Weigel, P.H.4    Oka, J.A.5    Goldblum, R.M.6
  • 135
    • 0033956711 scopus 로고    scopus 로고
    • Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells
    • J.C. Leung, A.W. Tsang, D.T. Chan, and K.N. Lai Absence of CD89, polymeric immunoglobulin receptor, and asialoglycoprotein receptor on human mesangial cells J Am Soc Nephrol 11 2 2000 241 249 (Pubitemid 30064847)
    • (2000) Journal of the American Society of Nephrology , vol.11 , Issue.2 , pp. 241-249
    • Leung, J.C.K.1    Tsang, A.W.L.2    Chan, D.T.M.3    Lai, K.N.4
  • 136
    • 0035991411 scopus 로고    scopus 로고
    • Interactions of human mesangial cells with IgA and IgA-containing immune complexes
    • DOI 10.1046/j.1523-1755.2002.00477.x
    • J. Novak, H.L. Vu, L. Novak, B.A. Julian, J. Mestecky, and M. Tomana Interactions of human mesangial cells with IgA and IgA-containing immune complexes Kidney Int 62 2 2002 465 475 (Pubitemid 34779757)
    • (2002) Kidney International , vol.62 , Issue.2 , pp. 465-475
    • Novak, J.1    Vu, H.L.2    Novak, L.3    Julian, B.A.4    Mestecky, J.5    Tomana, M.6
  • 139
    • 0031820723 scopus 로고    scopus 로고
    • Down-regulation of Fcα receptors on blood cells of IgA nephropathy patients: Evidence for a negative regulatory role of serum IgA
    • DOI 10.1046/j.1523-1755.1998.00885.x
    • B. Grossetete, P. Launay, A. Lehuen, P. Jungers, J.F. Bach, and R.C. Monteiro Down-regulation of Fc alpha receptors on blood cells of IgA nephropathy patients: evidence for a negative regulatory role of serum IgA Kidney Int 53 5 1998 1321 1335 (Pubitemid 28316894)
    • (1998) Kidney International , vol.53 , Issue.5 , pp. 1321-1335
    • Grossetete, B.1    Launay, P.2    Lehuen, A.3    Jungers, P.4    Bach, J.-F.5    Monteiro, R.C.6
  • 141
  • 142
    • 8344262361 scopus 로고    scopus 로고
    • Injection of recombinant FcalphaRI/CD89 in mice does not induce mesangial IgA deposition
    • P.J. van der Boog, C. van Kooten, and G. van Zandbergen Injection of recombinant FcalphaRI/CD89 in mice does not induce mesangial IgA deposition Nephrol Dial Transplant 19 11 2004 2729 2736
    • (2004) Nephrol Dial Transplant , vol.19 , Issue.11 , pp. 2729-2736
    • Van Der Boog, P.J.1    Van Kooten, C.2    Van Zandbergen, G.3
  • 144
    • 78649659186 scopus 로고    scopus 로고
    • Association of soluble CD89 levels with disease progression but not susceptibility in IgA nephropathy
    • M.T. Vuong, M. Hahn-Zoric, and S. Lundberg Association of soluble CD89 levels with disease progression but not susceptibility in IgA nephropathy Kidney Int 78 12 2010 1281 1287
    • (2010) Kidney Int , vol.78 , Issue.12 , pp. 1281-1287
    • Vuong, M.T.1    Hahn-Zoric, M.2    Lundberg, S.3
  • 145
    • 42149085674 scopus 로고    scopus 로고
    • Inhibitory ITAM signaling by Fc alpha RI-FcR gamma chain controls multiple activating responses and prevents renal inflammation
    • Y. Kanamaru, S. Pfirsch, and M. Aloulou Inhibitory ITAM signaling by Fc alpha RI-FcR gamma chain controls multiple activating responses and prevents renal inflammation J Immunol 180 4 2008 2669 2678
    • (2008) J Immunol , vol.180 , Issue.4 , pp. 2669-2678
    • Kanamaru, Y.1    Pfirsch, S.2    Aloulou, M.3
  • 149
    • 0023684844 scopus 로고
    • Activation of complement in IgA nephropathy
    • R.J. Wyatt, and B.A. Julian Activation of complement in IgA nephropathy
    • (1988) Am J Kidney Dis , vol.12 , Issue.5 , pp. 437-442
    • Wyatt, R.J.1    Julian, B.A.2
  • 150
    • 0031822961 scopus 로고    scopus 로고
    • Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy
    • DOI 10.1093/ndt/13.8.1984
    • M. Endo, H. Ohi, I. Ohsawa, T. Fujita, M. Matsushita, and T. Fujita Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy Nephrol Dial Transplant 13 8 1998 1984 1990 (Pubitemid 28356763)
    • (1998) Nephrology Dialysis Transplantation , vol.13 , Issue.8 , pp. 1984-1990
    • Endo, M.1    Ohi, H.2    Ohsawa, I.3    Fujita, T.4    Matsushita, M.5    Fujita, T.6
  • 151
    • 0345059320 scopus 로고    scopus 로고
    • Glomerular deposition of mannose-binding lectin in human glomerulonephritis
    • K. Lhotta, R. Wurzner, and P. Konig Glomerular deposition of mannose-binding lectin in human glomerulonephritis Nephrol Dial Transplant 14 4 1999 881 886 (Pubitemid 29155140)
    • (1999) Nephrology Dialysis Transplantation , vol.14 , Issue.4 , pp. 881-886
    • Lhotta, K.1    Wurzner, R.2    Konig, P.3
  • 153
    • 60749132251 scopus 로고    scopus 로고
    • Mesangial C4d deposition: A new prognostic factor in IgA nephropathy
    • M. Espinosa, R. Ortega, and J.M. Gomez-Carrasco Mesangial C4d deposition: a new prognostic factor in IgA nephropathy Nephrol Dial Transplant 24 3 2009 886 891
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.3 , pp. 886-891
    • Espinosa, M.1    Ortega, R.2    Gomez-Carrasco, J.M.3
  • 154
    • 15944365160 scopus 로고    scopus 로고
    • Activation of the lectin complement pathway in Henoch-Schönlein purpura nephritis
    • DOI 10.1053/j.ajkd.2004.10.020
    • S. Hisano, M. Matsushita, T. Fujita, and H. Iwasaki Activation of the lectin complement pathway in Henoch-Schonlein purpura nephritis Am J Kidney Dis 45 2 2005 295 302 (Pubitemid 40431055)
    • (2005) American Journal of Kidney Diseases , vol.45 , Issue.2 , pp. 295-302
    • Hisano, S.1    Matsushita, M.2    Fujita, T.3    Iwasaki, H.4
  • 155
    • 0037231850 scopus 로고    scopus 로고
    • Polymeric IgA increases the synthesis of macrophage migration inhibitory factor by human mesangial cells in IgA nephropathy
    • DOI 10.1093/ndt/18.1.36
    • J.C. Leung, S.C. Tang, L.Y. Chan, A.W. Tsang, H.Y. Lan, and K.N. Lai Polymeric IgA increases the synthesis of macrophage migration inhibitory factor by human mesangial cells in IgA nephropathy Nephrol Dial Transplant 18 1 2003 36 45 (Pubitemid 36104476)
    • (2003) Nephrology Dialysis Transplantation , vol.18 , Issue.1 , pp. 36-45
    • Leung, J.C.K.1    Tang, S.C.W.2    Chan, L.Y.Y.3    Tsang, A.W.L.4    Lan, H.Y.5    Lai, K.N.6
  • 156
    • 0033659379 scopus 로고    scopus 로고
    • Aberrantly glycosylated IgA molecules downregulate the synthesis and secretion of vascular endothelial growth factor in human mesangial cells
    • A. Amore, G. Conti, and P. Cirina Aberrantly glycosylated IgA molecules downregulate the synthesis and secretion of vascular endothelial growth factor in human mesangial cells Am J Kidney Dis 36 6 2000 1242 1252
    • (2000) Am J Kidney Dis , vol.36 , Issue.6 , pp. 1242-1252
    • Amore, A.1    Conti, G.2    Cirina, P.3
  • 157
    • 0344667757 scopus 로고    scopus 로고
    • Polymeric IgA1 from Patients with IgA Nephropathy Upregulates Transforming Growth Factor-β Synthesis and Signal Transduction in Human Mesangial Cells via the Renin-Angiotensin System
    • DOI 10.1097/01.ASN.0000095639.56212.BF
    • K.N. Lai, S.C. Tang, and J.Y. Guh Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system J Am Soc Nephrol 14 12 2003 3127 3137 (Pubitemid 37509290)
    • (2003) Journal of the American Society of Nephrology , vol.14 , Issue.12 , pp. 3127-3137
    • Lai, K.N.1    Tang, S.C.W.2    Guh, J.-Y.3    Chuang, T.-D.4    Lam, M.F.5    Chan, L.Y.Y.6    Tsang, A.W.L.7    Leung, J.C.K.8
  • 159
    • 0034863147 scopus 로고    scopus 로고
    • Glycosylation of circulating IgA in patients with IgA nephropathy modulates proliferation and apoptosis of mesangial cells
    • A. Amore, P. Cirina, G. Conti, P. Brusa, L. Peruzzi, and R. Coppo Glycosylation of circulating IgA in patients with IgA nephropathy modulates proliferation and apoptosis of mesangial cells J Am Soc Nephrol 12 9 2001 1862 1871 (Pubitemid 32801361)
    • (2001) Journal of the American Society of Nephrology , vol.12 , Issue.9 , pp. 1862-1871
    • Amore, A.1    Cirina, P.2    Conti, G.3    Brusa, P.4    Peruzzi, L.5    Coppo, R.6
  • 161
    • 58049206800 scopus 로고    scopus 로고
    • Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy
    • K.N. Lai, J.C. Leung, and L.Y. Chan Podocyte injury induced by mesangial-derived cytokines in IgA nephropathy Nephrol Dial Transplant 24 1 2009 62 72
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.1 , pp. 62-72
    • Lai, K.N.1    Leung, J.C.2    Chan, L.Y.3
  • 162
    • 76749143681 scopus 로고    scopus 로고
    • Aberrantly glycosylated IgA1 induces mesangial cells to produce platelet-activating factor that mediates nephrin loss in cultured podocytes
    • R. Coppo, V. Fonsato, and S. Balegno Aberrantly glycosylated IgA1 induces mesangial cells to produce platelet-activating factor that mediates nephrin loss in cultured podocytes Kidney Int 77 5 2010 417 427
    • (2010) Kidney Int , vol.77 , Issue.5 , pp. 417-427
    • Coppo, R.1    Fonsato, V.2    Balegno, S.3
  • 163
    • 12344335072 scopus 로고    scopus 로고
    • Activation of tubular epithelial cells by mesangial-derived TNF-α: Glomerulotubular communication in IgA nephropathy
    • DOI 10.1111/j.1523-1755.2005.67116.x
    • L.Y. Chan, J.C. Leung, A.W. Tsang, S.C. Tang, and K.N. Lai Activation of tubular epithelial cells by mesangial-derived TNF-alpha: glomerulotubular communication in IgA nephropathy Kidney Int 67 2 2005 602 612 (Pubitemid 40139851)
    • (2005) Kidney International , vol.67 , Issue.2 , pp. 602-612
    • Chan, L.Y.Y.1    Leung, J.C.K.2    Tsang, A.W.L.3    Tang, S.C.W.4    Lai, K.N.5
  • 165
    • 79952163845 scopus 로고    scopus 로고
    • Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy II. Light microscopic and clinical studies
    • K. El Karoui, G.S. Hill, and A. Karras Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy II. Light microscopic and clinical studies Kidney Int 79 6 2011 643 654
    • (2011) Kidney Int , vol.79 , Issue.6 , pp. 643-654
    • El Karoui, K.1    Hill, G.S.2    Karras, A.3
  • 166
    • 68949218774 scopus 로고    scopus 로고
    • The Oxford classification of IgA nephropathy: Rationale, clinicopathological correlations, and classification
    • D.C. Cattran, R. Coppo, and H.T. Cook The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification Kidney Int 76 5 2009 534 545
    • (2009) Kidney Int , vol.76 , Issue.5 , pp. 534-545
    • Cattran, D.C.1    Coppo, R.2    Cook, H.T.3
  • 167
    • 68949206247 scopus 로고    scopus 로고
    • The Oxford classification of IgA nephropathy: Pathology definitions, correlations, and reproducibility
    • I.S. Roberts, H.T. Cook, and S. Troyanov The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility Kidney Int 76 5 2009 546 556
    • (2009) Kidney Int , vol.76 , Issue.5 , pp. 546-556
    • Roberts, I.S.1    Cook, H.T.2    Troyanov, S.3
  • 168
    • 79952174502 scopus 로고    scopus 로고
    • Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy I. Immunohistochemical studies
    • G.S. Hill, K.E. Karoui, and A. Karras Focal segmental glomerulosclerosis plays a major role in the progression of IgA nephropathy I. Immunohistochemical studies Kidney Int 79 6 2011 635 642
    • (2011) Kidney Int , vol.79 , Issue.6 , pp. 635-642
    • Hill, G.S.1    Karoui, K.E.2    Karras, A.3
  • 170
    • 38149107161 scopus 로고    scopus 로고
    • A new look at platelet-derived growth factor in renal disease
    • J. Floege, F. Eitner, and C.E. Alpers A new look at platelet-derived growth factor in renal disease J Am Soc Nephrol 19 1 2008 12 23
    • (2008) J Am Soc Nephrol , vol.19 , Issue.1 , pp. 12-23
    • Floege, J.1    Eitner, F.2    Alpers, C.E.3
  • 171
    • 69249123225 scopus 로고    scopus 로고
    • Patients with IgA nephropathy exhibit high systemic PDGF-DD levels
    • P. Boor, F. Eitner, and C.D. Cohen Patients with IgA nephropathy exhibit high systemic PDGF-DD levels Nephrol Dial Transplant 24 9 2009 2755 2762
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.9 , pp. 2755-2762
    • Boor, P.1    Eitner, F.2    Cohen, C.D.3
  • 172
    • 78049369136 scopus 로고    scopus 로고
    • Renal fibrosis: Novel insights into mechanisms and therapeutic targets
    • P. Boor, T. Ostendorf, and J. Floege Renal fibrosis: novel insights into mechanisms and therapeutic targets Nat Rev 6 11 2010 643 656
    • (2010) Nat Rev , vol.6 , Issue.11 , pp. 643-656
    • Boor, P.1    Ostendorf, T.2    Floege, J.3
  • 174
    • 78149298226 scopus 로고    scopus 로고
    • Mechanisms of tubulointerstitial fibrosis
    • M. Zeisberg, and E.G. Neilson Mechanisms of tubulointerstitial fibrosis J Am Soc Nephrol 21 11 2010 1819 1834
    • (2010) J Am Soc Nephrol , vol.21 , Issue.11 , pp. 1819-1834
    • Zeisberg, M.1    Neilson, E.G.2
  • 175
    • 78649669329 scopus 로고    scopus 로고
    • Mechanistic connection between inflammation and fibrosis
    • S.B. Lee, and R. Kalluri Mechanistic connection between inflammation and fibrosis Kidney Int Suppl 119 2010 S22 S26
    • (2010) Kidney Int Suppl , vol.119
    • Lee, S.B.1    Kalluri, R.2
  • 176
    • 85080838348 scopus 로고    scopus 로고
    • Special series: Chronic kidney disease growth factors in renal fibrosis
    • P. Boor, and J. Floege Special series: chronic kidney disease growth factors in renal fibrosis Clin Exp Pharmacol Physiol 38 7 2011 391 400
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , Issue.7 , pp. 391-400
    • Boor, P.1    Floege, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.