Deletion insertion polymorphism of the angiotensin converting enzyme gene and progression of diabetic nephropathy

Nephrology Dialysis Transplantation

Volumn 12, Issue SUPPL. 2, 1997, Pages 67-70

  Björck, Staffan ^a   Blohmé, Göran ^a   Sylvén, Christer ^b   Mulec, Henrik ^c  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c Department of Nephrology   (Sweden)

Author keywords

Angiotensin converting enzyme gene; Diabetic; Insulin dependent diabetes mellitus; Nephropathy; Polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; ARTICLE; BLOOD PRESSURE REGULATION; DIABETIC NEPHROPATHY; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE; DNA POLYMORPHISM; FEMALE; GENE DELETION; GENE INSERTION; GENOTYPE; GLOMERULUS FILTRATION RATE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK FACTOR; SYSTOLIC BLOOD PRESSURE;

ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; BODY WEIGHT; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; DNA TRANSPOSABLE ELEMENTS; FEMALE; GENE DELETION; GENE FREQUENCY; GENOTYPE; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES;

EID: 0030815913     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/12.1.67     Document Type: Article

References (24)

1. Andersen AR, Christiansen JS, Andersen JK, Kreiner S, Deckert T. Diabetic nephropathy in type 1 (insulin-dependent) diabetes: an epidemiological study. Diabetologia 1983; 25: 496-501
2. Parving H-H, Andersen AR, Smidt UM, Hommel E, Mathiesen ER, Svendsen PA. Effect of antihypertensive treatment on kidney function in diabetic nephropathy. Br Med J 1987; 294: 1443-1447
3. Lewis EJ, Hunsicker LG, Bain RP and Rohde R, for the collaborative study group. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med 1993; 329: 1456-1462
4. Mulec H, Johnsen SA, Wiklund O, Björck S. Cholesterol, a renal risk factor in diabetic nephropathy? Am J Kidney Dis 1993; 22: 196-201
5. Zeller K, Whittaker E,Sullivan L, Raskin P, Jacobson HR: Effect of restricting dietary protein on progression of renal failure in patients with insulin-dependent diabetes mellitus. N Engl J Med 1991; 324: 78-84
6. Björck S, Mulec H, Johnsen SA, Nordén G, Aurell M. Renal protective effect of enalapril in diabetic nephropathy. Br Med J 1992; 304: 339-343
7. Lieberman J, Sastre A. Serum angiotensin-converting enzyme: elevations in diabetes mellitus. Ann Int Med 1980; 93: 825-826
8. Rigat B, Hubert C, Corvol P. Soubrier F: PCR detection of the insertion/deletion polymorphism of the human angiotensin convening enzyme gene (DCPI) (dipeptidyl car boxypepfidase 1). Nucleic Acids Res 1992; 20: 1433
9. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard JM, Bara L, Ricard S, Tiret L, Amouyel Ph, Alhenc-Gelas F, Soubrier F. Deletion polymorphism in the gene for angiotensin converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-44
10. Brøchner-Mortensen J. A simple method for the determination of glomerular filtration rate. Scan J clin. Lab Invest 1972; 30: 271-274
11. Andersson B, Sylvén C. The DD genotype of the angiotensin converting enzyme gene is associated with increased mortality in idiopathic heart failure. J Am Coll Cardiol 1996 in press
12. Fogarty DC, Maxwell AP, Doherty CC, Hughes AE, Nervin NC. ACE gene typing. Lancet 1994; 343: 851
13. Tarnow L, Cambien F, Rossing P, Nieisen FS, Hansen BV, Lecerf L, Poirier O, Danilov S, Parving H-H. Lack of relationship between an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients. Diabetes 1995; 44: 489-494
14. Schmidt S, Schone N, Ritz E. Association of ACE gene polymorphism and diabetic nephropathy? The Diabetic Nephropathy Study Group. Kidney Int 1995; 47: 1176-1181
15. Hannedoche T, Landais P, Goldfarb, Esper NEI, Fournier A, Godin M, Durand D, Chanard J, Mignon F, Suc J-M, Grünfeld J-P. Randomised controlled trial of enalapril and β blockers in non-diabetic renal failure. Br Med J 1994; 309: 833-837
16. Ballerman BJ, Zeidel ML, Gunning ME, Brenner BM. Vasoactive petides and the kidney. In: Brenner & Rector, ed. The Kidney. Saunders, Philadelphia 1991: 510-583
17. Harden PN, Geddes C, Rowe PA, McIlroy JH, Boulton-Jones M, Rodger RS, Junor BJ, Briggs JD, Connell JM, Jardine AG. Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy. Lancet 1995; 345: 1540-1542
18. Tarnow L, Rossing P, Jacobsen P, Nielsen FS, Cambien F, Lecerf L, Poirier O, Parving H-H. Progression of diabetic nephropathy and the insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene. Journal of the American Society of Nephrology (abstract) 1995; 6: 457
19. Jacobsen P, Tarnow L, Rossing P, Cambien F, Lecerf L, Poirier O, Parving H-H. The insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene predicts the progression of diabetic nephropathy during ACE inhibition in insulin dependent diabetic patients. Journal of the American Society of Nephrology (abstract) 1995; 6: 450
20. van Essen GG, Rensma PL, de Zeeuw D, Sluiter WJ, Scheffer H, Apperloo AJ, de Jong PE. Association between the angiotensin-converting enzyme gene polymorphism and failure of renoprotective therapy. Lancet 1996; 347: 94-96
21. Yoshida H, Mitarai T, Kawamura T, Kitajima T, Miyazaki Y, Nagasawa R, Kawagushi Y, Kubo H, Ichikawa I, Sakai O. Role of the progression and therapeutic responsiveness of IgA nephropathy. J Clin Invest 1995; 96: 2100-2102
22. Motiyama T, Kitamura H, Izumi M, Yokoyama K, Yamauchi A, Ueda N, Kamado T, Imai E. Association of angiotensin-I-converting enzyme polymorphism with susceptibility to antiproteinuric effect of angiotensin-I-converting enzyme inhibitors in patients with proteinuria. J Am Soc Nephrol 1995; 6: 1674-1678
23. Hunley TE, Julian BA, Phillips JA, Summar ML, Yoshida H, Horn RG, Brown NJ, Fogo A, Ichikawa I, Kon V. angiotensin-I-converting enzyme polymorphism: potential silencer motif and impact on progression in IgA nephropathy. Kidney Int 1996; 49: 571-577
24. Parving H-H. Rossing P, Hommel E, Smidt UM. Angiotensin-converting enzyme inhibition in diabetic nephropathy: ten years experience. Am J Kidney Dis 1995; 26: 99-107