Remission of IgA nephropathy after allogeneic peripheral blood stem cell transplantation followed by immunosuppression for acute lymphocytic leukemia

Internal Medicine

Volumn 45, Issue 22, 2006, Pages 1291-1295

  Iwata, Yasunori ^a   Wada, Takashi ^c   Uchiyama, Akio ^a   Miwa, Atsuo ^a   Nakaya, Izaya ^a   Tohyama, Tadashi ^a   Yamada, Yuhji ^a   Kurokawa, Toshiro ^a   Yoshida, Takashi ^a   Ohta, Satoshi ^b   Yokoyama, Hitoshi ^d   Iida, Hiroyuki ^a  

^a TOYAMA PREFECTURAL CENTRAL HOSPITAL   (Japan)

^b TOYAMA CITY HOSPITAL   (Japan)

^c KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

^d KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

ALL; IgA nephropathy; PBSCT

Indexed keywords

COMPLEMENT COMPONENT C3; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; IMMUNOGLOBULIN A; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; METHYLPREDNISOLONE; MITOXANTRONE; PREDNISOLONE; TACROLIMUS; VINCRISTINE;

ACUTE LYMPHOCYTIC LEUKEMIA; ADULT; ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; ARTICLE; CANCER MORTALITY; CASE REPORT; COMPLEMENT DEPOSITION; CONCENTRATION (PARAMETERS); ELECTRON MICROSCOPY; GRAFT VERSUS HOST REACTION; HEMATURIA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN DEPOSITION; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY BIOPSY; MALE; MICROSCOPY; PROTEIN BLOOD LEVEL; PROTEINURIA; REMISSION; STEROID THERAPY; TREATMENT FAILURE;

ADULT; GLOMERULONEPHRITIS, IGA; HUMANS; IMMUNOSUPPRESSION; KIDNEY; LEUKEMIA, LYMPHOCYTIC, ACUTE; MALE; PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; REMISSION INDUCTION;

EID: 33845615540     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.45.1837     Document Type: Article

References (25)

1. Tyndall A, Gratwohl A. Blood and marrow stem cell transplants in autoimmune disease. A consensus report written on behalf of the European League Against Rheumatism (EULAR) and the European Group for Blood and Marrow Transplantation (EBMT). Br J Rheumatol 36: 390-392, 1997.
2. Bekkum DW. Immune, ablation and stem-cell therapy in autoimmune disease. Experimental basis for autologous stem-cell transplantation. Arthritis Res 2: 281-284, 2000.
3. Van Laar JM, Tyndall A. Intense immunosuppression and stemcell transplantation for patients with severe rheumatic autoimmune disease: a review. Cancer Control 10: 57-65, 2003.
4. Takeuchi K, Inaba M, Miyashima S, Ogawa R, Ikehara S. A new strategy for treatment of autoimmune diseases in chimeric resistant MRL/lpr mice. Blood 91: 4616-4623, 1998.
5. Imasawa T, Nagasawa R, Utsunomiya Y, et al. Bone marrow transplantation attenuates murine IgA nephropathy: role of a stem cell disorder. Kidney Int 56: 1809-1817, 1999.
6. Ito T, Suzuki A, Imai E, Okabe M, Hori M. Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling. J Am Soc Nephrol 12: 2625-2635, 2001.
7. Rookmaaker MB, Smits AM, Tolboom H, et al. Bone-marrow-derived cells contribute to glomerular endothelial repair in experimental glomerulonephritis. Am J Pathol 163: 553-562, 2003.
8. Ponticelli C, Traversi L, Feliciani A, et al. Kidney transplantation in patients with IgA mesangial glomerulonephritis. Kidney Int 60: 1948-1954, 2001.
9. Koselj M, Rott T, Kandus A, et al. Donor-transmitted IgA nephropathy: long-term follow-up of kidney donors and recipients. Transplant Proc 29: 3406-3407, 1997.
10. Sakai H. Cellular immunoregulatory aspects of IgA nephropathy. Am J Kidney Dis 12: 430-432, 1988.
11. van der Boog PJ, van Kooten C, de Fijter JW, Daha MR. Role of macromolecular IgA in IgA nephropathy. Kidney Int 67: 813-821, 2005.
12. Yasuda Y, Horie A, Odani H, et al. Application of mass spectrometry to IgA nephropathy: structural and biological analyses of underglycosylated IgA1 molecules. Contrib Nephrol 141: 170-188, 2004.
13. Alison MR, Poulsom R, Jeffery R, et al. Hepatocytes from nonhepatic adult stem cells. Nature 406: 257, 2000.
14. Mezey E, Key S, Vogelsang G, et al. Transplanted bone marrow generates new neurons in human brains. Proc Natl Acad Sci U S A 100: 1364-1369, 2003.
15. Quaini F, Urbanek K, Beltrami AP, et al. Chimerism of the transplanted heart. N Engl J Med 346: 5-15, 2002.
16. Korbling M, Katz RL, Khanna A, et al. Hepatocytes, and epithetial cells of donor origin in recipients of peripheral-blood stem cells. N Engl J Med 346: 738-746, 2002.
17. Taylor HS. Endometrial cells derived from donor stem cells in bone marrow transplant recipients. JAMA 292: 81-85, 2004.
18. Imasawa T, Utsunomiya Y, Kawamura T, et al. The potential of bone marrow-derived cells to differentiate to glomerular mesangial cells. J Am Soc Nephrol 12: 1401-1409, 2001.
19. Tumlin JA, Lohavichan V, Hennigar R. Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide. Nephrol Dial Transplant 18: 1321-1329, 2003.
20. Walker RG, Yu SH, Owen JE, Kincaid-Smith P. The treatment of mesangial IgA nephropathy with cyclophosphamide, dipyridamole and warfarin: a two-year prospective trial. Clin Nephrol 34: 103-107, 1990.
21. Tsuruya K, Harada A, Hirakata. H, et al. Combination therapy using prednisolone and cyclophosphamide slows the progression of moderately advanced IgA nephropathy. Clin Nephrol 53: 1-9, 2000.
22. Roccatello D, Ferro M, Cesano G, et al. Steroid and cyclophosphamide in IgA nephropathy. Nephrol Dial Transplant 15: 833-835, 2000.
23. Ballardie FW, Roberts IS. Controlled prospective trial of prednisolone and cytotoxics in progressive IgA nephropathy. J Am Soc Nephrol 13: 142-148, 2002.
24. Loeffler K, Gowrishankar M, Yin V Tacrolimus therapy in pediatric patients with treatment-resistant nephritic syndrome. Pediatr Nephrol 19: 281-287, 2004.
25. Hotta O, Furuta T, Chiba S, et al. Regression of IgA nephropathy: a repeat biopsy study. Am J Kidney Dis 39: 493-502, 2002.