Fcα receptor (CD89) mediates the development of immunoglobulin a (IgA) nephropathy (Berger's disease): Evidence for pathogenic soluble receptor-IgA complexes in patients and CD89 transgenic mice

Journal of Experimental Medicine

Volumn 191, Issue 11, 2000, Pages 1999-2009

  Launay, Pierre ^a   Grossetête, Béatrice ^a   Arcos Fajardo, Michelle ^a   Gaudin, Emmanuelle ^a   Torres, Sonia P ^a   Beaudoin, Lucie ^a   De Serre, Natacha Patey Mariaud ^a   Lehuen, Agnès ^a   Monteiro, Renato C ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Fc receptor; IgA; IgA nephropathy; Monocytes; Transgenic mice

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN FC FRAGMENT; DNA BINDING PROTEIN; FC RECEPTOR; FC(ALPHA) RECEPTOR; LEUKOCYTE ANTIGEN; NUCLEAR PROTEIN; RAG2 PROTEIN, HUMAN; RAG2 PROTEIN, MOUSE; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

ANIMAL CELL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GLOMERULONEPHRITIS; HEMATURIA; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; ANIMAL; GENETICS; IMMUNOLOGY; MOUSE MUTANT; PATHOLOGY; SOLUBILITY; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD; DNA-BINDING PROTEINS; FEMALE; GLOMERULONEPHRITIS, IGA; HEMATURIA; HUMANS; IMMUNOGLOBULIN A; MALE; MICE; MICE, KNOCKOUT; MICE, SCID; MICE, TRANSGENIC; NUCLEAR PROTEINS; RECEPTORS, FC; SOLUBILITY;

EID: 0034608117     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.11.1999     Document Type: Article

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