Reduced binding of immunoglobulin A (IgA) from patients with primary IgA nephropathy to the myeloid IgA Fc-receptor, CD89

Nephrology Dialysis Transplantation

Volumn 13, Issue 12, 1998, Pages 3058-3064

  Van Zandbergen, Ger ^a   Van Kooten, Cees ^a   Mohamad, Naigsah Klar ^a   Reterink, Thomas J F ^a   De Fijter, Johan W ^a   Van De Winkel, Jan G J ^b,c   Daha, Mohamed R ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c Medarex Europe   (Netherlands)

Author keywords

CD89; Fc receptor IgA; IgAN

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN A;

ADULT; ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN DEPOSITION; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0031726488     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/13.12.3058     Document Type: Article

References (26)

1. Feehally J. IgA nephropathy- a disorder of IgA production? Q J Med 1997; 90: 387-390
2. van Es LA, de Fijter JW, Daha MR. Pathogenesis of IgA nephropathy. Nephrology 1997; 3: 3 12
3. van den Wall Bake AW, Daha MR, Haaijman JJ et al. Elevated production of polymeric and monomeric IgA1 by the bone marrow in IgA nephropathy. Kidney Int 1989; 35: 1400-1404
4. Morton HC, van Egmond M, van de Winkel JG. Structure and function of human IgA Fc receptors (Fc α R). Crit Rev Immunol 1996; 16: 423-440
5. Maliszewski CR, Shen L, Fanger MW. The expression of receptors for IgA on human monocytes and calcitriol-treated HL-60 cells. J Immunol 1985; 135: 3878-3881
6. Roccatello D, Picciotto G, Torchio M et al. Removal systems of immunoglobulin A and immunoglobulin A containing complexes in IgA nephropathy and cirrhosis patients. The role of asialoglycoprotein receptors. Lab Invest 1993; 69: 714-723
7. Maliszewski CR, March CJ, Schoenborn MA, Gimpel S, Shen L. Expression cloning of a human Fc receptor for IgA. J Exp Med 1990; 172: 1665-1672
8. Reterink TJF, Schroeijers WEM, van Es LA, Daha MR. Dimeric and polymeric IgA, but not monomeric IgA, enhance the production of IL-6 by human renal mesangial cells. Mediat Inflamm 1996; 5: 191 195
9. Reterink TJF, van Zandbergen G, Klar-Mohamad N, et al. Size-dependent effect of IgA on the IgA Fc receptor (CD89). Eur J Immunol 1997; 27: 2219 2224
10. Westerhuis R, van Zandbergen G, van Kooten C, et al. Human mesangial cells(MC) in culture and in kidney sections fail to express FcαR (CD89). JASN 1998; (in press)
11. Gomez-Guerrero C, Gonzalez E, Egido J. Evidence for a specific IgA receptor in rat and human mesangial cells. J Immunol 1993; 151: 7172 7181
12. Monteiro RC, Grossetete B, Nguyen AT, Jungers P, Lehuen A. Dysfunctions of Fcα receptors by blood phagocytic cells in IgA nephropathy. Contrib Nephrol 1995; 111: 116-122
13. Shen L, Lasser R, Fanger MW. My 43, a monoclonal antibody that reacts with human myeloid cells inhibits monocyte IgA binding and triggers function. J Immunol 1989; 143: 4117-4122
14. de Fijter JW, van den Wall Bake AW, Braam CA, van Es LA, Daha MR. Immunoglobulin A subclass measurement in serum and saliva: sensitivity of detection of dimeric IgA2 in ELISA depends on the antibody used. J Immunol Methods 1995; 187: 221-232
15. Morton HC, van den Herik-Oudijk IE, Vossebeld P, Snijders A, Verhoeven AJ, Capel PJ, van de Winkel JG. Functional association between the human myeloid immunoglobulin A Fc receptor (CD89) and FcR γ chain. Molecular basis for CD89/FcR γ chain association. J Biol Chem 1995; 270: 29781 29787
16. Hiemstra PS, Biewenga J, Gorter A, Stuurman ME, Faber A, van Es LA, Daha MR. Activation of complement by human serum IgA, secretory IgA and IgA1 fragments. Mol Immunol 1988; 25: 527-533
17. Chen A, Sheu LF, Ding SL, Lee WH. Monomeric immunoglobulin A protects glomerulus against polymeric immunoglobulin A immune complex in experimental immunoglobulin A nephropathy. Lab Invest 1996; 74: 737 746
18. Gomez-Guerrero C, Lopez-Armada MJ, Gonzalez E, Egido J. Soluble IgA and IgG aggregates are catabolized by cultured rat mesangial cells and induce production of TNF-α and IL-6, and proliferation. J Immunol 1994; 153: 5247-5255
19. Liu ZH, Striker GE, Stetler-Stevenson M, Fukushima P, Patel A, Striker LJ. TNF-α and IL-1 α induce mannose receptors and apoptosis in glomerular mesangial but not endothelial cells. Am J Physiol 1996; 270: C1595 C1601
20. Tomana M, Matousovic K, Julian BA, Radl J, Konecny K, Mestecky J. Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG. Kidney Int 1997; 52: 509-516
21. Carayannopoulos L, Hexham JM, Capra JD. Localization of the binding site for the monocyte immunoglobulin (Ig) A-Fc receptor (CD89) to the domain boundary between Gα2 and Gα3 in human IgA1. J Exp Med 1996; 183: 1579-1586
22. Lasseur C, Allen AC, Deminiere C, Aparicio M, Feehally J, Combe C. Henoch-Schonlein purpura with immunoglobulin A nephropathy and abnormalities of immunoglobulin A in a Wiskott-Aldrich syndrome carrier. Am J Kidney Dis 1997; 29: 285 287
23. Chuang PD, Morrison SL. Elimination of N-linked glycosylation sites from the human IgA1 constant region: effects on structure and function. J Immunol 1997; 158: 724-732
24. Allen AC, Harper SJ, Feehally J. Galactosylation of N-and O-linked carbohydrate moieties of IgA1 and IgG in IgA nephropathy. Clin Exp Immunol 1995; 100: 470-474
25. Mestecky J, Tomana M, Crowley-Nowick PA, Moidoveanu Z, Julian BA, Jackson S. Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy. Contrib Nephrol 1993; 104: 172-182
26. Sanfilippo F, Croker BP, Bollinger RR. Fate of four cadaveric donor renal allografts with mesangial IgA deposits. Transplantation 1982; 33: 370-376