Computational modeling and analysis of insulin induced eukaryotic translation initiation

PLoS Computational Biology

Volumn 7, Issue 11, 2011, Pages

  Lequieu, Joshua ^a   Chakrabarti, Anirikh ^a   Nayak, Satyaprakash ^a   Varner, Jeffrey D ^a  

^a Cornell University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX NETWORKS; FEEDBACK; GENE EXPRESSION; MULTIOBJECTIVE OPTIMIZATION; ORDINARY DIFFERENTIAL EQUATIONS;

BIOCHEMICAL INTERACTIONS; CELLULAR PROCESS; COMPUTATIONAL ANALYSIS; COMPUTATIONAL MODELLING; ENZYMATIC PROCESS; EUKARYOTIC TRANSLATION; GENES EXPRESSION; INSULIN SIGNALING; MASS ACTION KINETICS; MODELLING AND ANALYSIS;

INSULIN;

INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAPAMYCIN; RHEB PROTEIN; WORTMANNIN; INSULIN RECEPTOR SUBSTRATE;

ARTICLE; ENZYME ACTIVITY; ENZYME REGULATION; EUKARYOTE; KINETICS; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; PROTEIN FUNCTION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; ANIMAL; COMPUTER SIMULATION; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RNA TRANSLATION;

EUKARYOTA;

ANIMALS; COMPUTER SIMULATION; EUKARYOTA; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION;

EID: 81355150988     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002263     Document Type: Article

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