p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

Genes and Development

Volumn 10, Issue 9, 1996, Pages 1084-1095

  Lioubin, Mario N ^a,b   Algate, Paul A ^a   Tsai, Schickwann ^a   Carlberg, Kristen ^a   Aebersold, Ruedi ^b   Rohrschneider, Larry R ^a,b  

^a USA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Hematopoietic; Inositol polyphosphate 5 phosphatase; PTB domain; Shc; Signal transduction

Indexed keywords

COLONY STIMULATING FACTOR 1; INOSITOL POLYPHOSPHATE; PHOSPHATASE; COMPLEMENTARY DNA; GROWTH FACTOR RECEPTOR; HYBRID PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE 5 PHOSPHATASE; INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE; INPPL1 PROTEIN, HUMAN; ONCOPROTEIN; ORGANOPHOSPHATE; PHENYL PHOSPHATE; PHOSPHOTYROSINE; PROTEIN; PROTEIN TYROSINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; VASCULOTROPIN RECEPTOR 1; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL GROWTH; ENZYME ACTIVITY; ENZYME ANALYSIS; GROWTH INHIBITION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VIRUS EXPRESSION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL LINE; DRUG EFFECT; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; SEQUENCE ALIGNMENT; SRC HOMOLOGY DOMAIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA, COMPLEMENTARY; HEMATOPOIETIC STEM CELLS; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MOLECULAR SEQUENCE DATA; PHOSPHORIC ACID ESTERS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 0029665083     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.9.1084     Document Type: Article

References (60)

1. Aebersold, R.H., J. Leavitt, R.A. Saavedra, L.E. Hood, and S.B. Kent. 1987. Internal amino acid sequence analysis of proteins separated by one- or two-dimensional gel electrophoresis after in situ protease digestion on nitrocellulose. Proc. Nat. Acad. Sci. 84: 6970-6974.
2. Alonso, G., M. Koegl, N. Mazurenko, and S.A. Courtneidge. 1995. Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors. J. Biol. Chem. 270: 9840-9848.
3. Attree, O., I.M. Olivos, I. Okabe, L.C. Bailey, D.L. Nelson, R.A. Lewis, R.R. McInnes, and R.L. Nussbaum. 1992. The Lowe's oculocerebrorenal syndrome gene encodes a protein highly homologous to inositol polyphosphate-5-phosphatase. Nature 358: 239-242.
4. Bartel, P., C. Chien, R. Stemglanz, and S. Fields. 1993. Using the two-hybrid system to detect protein-protein interactions. In Cellular interactions in development: A practical approach (ed. D.A. Hartley), pp. 153-179. Oxford University Press, Oxford, UK.
5. Bernstein, A., L. Forrester, A.D. Reith, P. Dubreuil, and R. Rottapel. 1991. The murine W/c-kit and Steel loci and the control of hematopoiesis. Sem. Hematol. 28: 138-142.
6. Blaikie, P., D. Immanuel, J. Wu, N. Li, V. Yajnik, and B. Margolis. 1994. A region in She distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. J. Biol. Chem. 269: 32031-32034.
7. Bourette, R.P., G.M. Myles, K. Carlberg, and L.R. Rohrschneider. 1995. Uncoupling of the proliferation and differentiation signals mediated by the murine macrophage colony-stimulating factor receptor expressed in myeloid FDC-P1 cells. Cell Growth Differ. 6: 631-645.
8. Bowen-Pope, D.F., R.A. Seifert and R. Ross. 1985. The plateletderived growth factor receptor. In Control of animal cell proliferation (ed. A.L. Boynton and H.L. Leffert), pp. 281-312. Academic Press, New York, NY.
9. ras through the formation of a complex of receptor, Grb2 adapter protein, and SOS nucleotide exchange factor. Cell 73: 611-620.
10. Burgering, B.M.T. and P.J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376: 599-602.
11. Cardenas, M.E. and J. Heitman. 1995. FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity. EMBO J. 14: 5892-5907.
12. Carlberg, K. and L.R. Rohrschneider. 1994. The effect of activating mutations on dimerization, tyrosine phosphorylation, and internalization of the macrophage colony stimulating factor receptor. Mol. Biol. Cell 5: 81-95.
13. 4-binding protein as a member of the GAP1 family. Nature 376: 527-530.
14. Cutler, R.L., L. Liu, J.E. Damen, and G. Krystal. 1993. Multiple cytokines induce the tyrosine phosphorylation of She and its association with Grb2 in hemopoietic cells. J. Biol. Chem. 268: 21463-21465.
15. Dailey, D., G.L. Schieven, M.Y. Lim, H. Marquardt, T. Gilmore, J. Thorner, and G.S. Martin. 1990. Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity. Mol. Cell Biol. 10: 6244-6256.
16. Damen, J.E., L. Liu, R.L. Cutler, and G. Krystal. 1993. Erythropoietin stimulates the tyrosine phosphorylation of She and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein. Blood 82: 2296-2303.
17. Damen, J.E., L. Liu, P. Rosten, R.K. Humphries, A.B. Jefferson, P.W. Majerus, and G. Krystal. 1996. The 145-kD protein induced to associate with She by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase. Proc. Nat. Acad. Sci. 93: 1689-1693.
18. Duhrsen, U. and D. Metcalf. 1988. A model system for leukemic transformation of immortalized hemopoietic cells in irradiated recipient mice. Leukemia 2: 329-333.
19. Egan, S.E., B.W. Giddings, M.W. Brooks, L. Buday, A.M. Sizeland, and R.A. Weinberg. 1993. Association of SOS Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363: 45-51.
20. Fields, S. and R. Sternglanz. 1994. The two hybrid system: An assay for protein-protein interactions. Trends Genet. 10: 286-292.
21. Franke, T.F., S.I. Yang, T.O. Chan, K. Datta, A. Kazlauskas, D.K. Morrison, D.R. Kaplan, P.N. Tsichlis. 1995. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81: 727-736.
22. Gliniak, B.C. and L.R. Rohrschneider. 1990. Expression of the M-CSF receptor (c-fms proto-oncogene) is controlled posttranscriptionally by the dominant actions of GM-CSF or Multi-CSF (IL-3). Cell 63: 1073-1083.
23. Harder, K.W., P. Owen, L.K.H. Wong, R. Aebersold, I. Clark-Lewis, and F.R. Jirik. 1994. Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase β(HPTPβ) using synthetic phosphopeptides. Biochem. J. 298: 395-401.
24. 2 3-OH kinase. Nature 358: 157-159.
25. Heitman, J., N.R. Movva, and M.N. Hall. 1991. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253: 905-909.
26. Hejna, J.A., H. Saito, L.S. Merkens, T.V. Tittle, P.M. Jakobs, M.A. Whitney, M. Grompe, A.S. Friedberg, and R.E. Moses. 1995. Cloning and characterization of a human cDNA (INPPL1) sharing homology with inositol polyphosphate phosphatases. Genomics 29: 285-287.
27. Jackson, S.P., S.M. Schoenwaelder, M. Matzaris, S. Brown, and C.A. Mitchell. 1995. Phosphatidylinositol 3,4,5-triphosphate is a substrate for the 75 kDa inositol polyphosphate5-phosphatase and a novel 5-phosphatase which forms a complex with the p85/p110 form of phosphoinositide 3-kinase. EMBO J. 14: 4490-4500.
28. Kashishian, A. and J.A. Cooper. 1993. Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase Cγ1. Mol. Biol. Cell 4: 49-57.
29. Kavanaugh, W.M. and L.T. Williams. 1994. An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science 266: 1862-1865.
30. Keegan, K. and J.A. Cooper. 1996. Use of the two-hybrid system to detect the association of the protein-tyrosinc-phosphatase SHPTP2 with another SH2-containing protein, Grb7. Oncogene 12: 1537-1544.
31. Li, N., A. Batzer, R. Daly, V. Yajnik, E. Skolnik, P. Chardin, D. Bar-Sagi, B. Margolis, and J. Schlessinger. 1993. Guaninenucleotide-releasing factor hSOS1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling. Nature 363: 85-88.
32. Lioubin, M.N., G.M. Myles, K. Carlberg, D. Bowtell, and L.R. Rohrschneider. 1994. SHC, GRB2, SOS1 and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells. Mol. Cell. Biol. 14: 5682-5691.
33. Liu, L., J.E. Damen, R.L. Cutler, and G. Krystal. 1994. Multiple cytokines stimulate the binding of a common 145-kilodalton protein to She at the Grb2 recognition site of She. Mol. Cell. Biol. 14: 6926-6935.
34. Miller, A.D. and G.J. Rosman. 1989. Improved retroviral vectors for gene transfer and expression. BioTechniques 7: 980-990.
35. Muench, M.O., M.G. Roncarolo, S. Menon, Y. Xu, R. Kastelein, S. Zurawski, C.H. Hannum, J. Culpepper, F. Lee, and R. Namikawa. 1995. FLK-2/FLT-3 ligand regulates the growth of early myeloid progenitors isolated from human fetal liver. Blood 85: 963-972.
36. Reedijk, M., X. Liu, P. van der Geer, K. Letwin, M.D. Waterfield, T. Hunter, and T. Pawson. 1992. Tyr721 regulates specific binding of the CSF-1 receptor kinasc insert to PI 3'-kinase SH2 domains: A model for SH2-mediated receptor-target interactions. EMBO J. 11: 1365-1372.
37. Ren, R., B.J. Mayer, P. Cicchctti, D. Baltimore. 1993. Identification of a ten-amino acid proline-rich SH3 binding site. Science 259: 1157-1161.
38. Rohrschneider, L.R. 1995. The macrophage-colony stimulating factor (M-CSF) receptor. In Guidebook to cytokines and their receptors (ed. A. Nicola), pp. 168-170. Oxford University Press, Oxford, UK.
39. Rohrschneider, L.R. and D. Metcalf. 1989. Induction of macrophage colony stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-Pl cells. Mol. Cell. Biol. 9: 5081-5092.
40. Rosnet, O., S. Marchetto, O. deLapeyriere, and D. Birnbaum. 1991. Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSFIR family. Oncogene 6: 1641-1650.
41. Rozakis-Adcock, M., R. Fernley, J. Wade, T. Pawson, and D. Bowtell. 1993. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSOS1. Nature 363: 83-85.
42. Saraste, M., P.R. Sibbald, and A. Wittinghofer. 1990. The P-loop - A common motif in ATP- and GTP-binding proteins. Trends Bio. Sci. 15: 430-434.
43. Savitsky, K., A. Bar-Shira, S. Gilad, G. Rotman, Y. Ziv, L. Vanagaite, D.A. Tagle, S. Smith, T. Uziel, S. Sfez, M. Ashkenazi, I. Pecker, M. Frydman, R. Harnik, S.R. Patanjali, A. Simmons, G.A. Clines, A. Sartiel, R.A. Gatti, L. Chessa, O. Sanal, M.F. Lavin, N.G.J. Jaspers, A.M.R. Taylor, C.F. Arlett, T. Miki, S.M. Weissman, M. Lovett, F.S. Collins, and Y. Shiloh. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749-1753.
44. iras oncoprotein activators SHC and mSOS1 as well as assembly of complexes containing SHC, GRB-2, mSOS1, and a 145-kD tyrosine-phosphorylated protein. J. Immunol. 153: 623-636.
45. 1 cyclin-dependent kinases. Genes &. Dev. 9: 1149-1163.
46. Smith, D.B. and K.S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40.
47. Songyang, Z. and L.C. Cantley. 1995. Recognition and specificity in protein tyrosine kinase-mediated signalling. Trends Biochem. Sci. 20: 470-475.
48. Stephens, L.R., K.T. Hughes, and R.F. Irvine. 1991. Pathway of phosphatidylinositol(3,4,5)-triphosphate synthesis in activated neutrophils. Nature 351: 33-39.
49. Strathdee, C.A., H. Gavish, W.R. Shannon, and M. Buchwald. 1992. Cloning of cDNAs for Fanconi's anaemia by functional complementation. Nature 356: 763-767.
50. 3. J. Biol. Chem. 269: 32358-32367.
51. Traynor-Kaplan, A.E., A.L. Harris, B.L. Thompson, P. Taylor, and L.A. Sklar. 1988. An inositol tetrakisphosphate-containing phospholipid in activated neutrophils. Nature 334: 353-356.
52. Tsai, S., S. Bartelmez, E. Sitnicka, and S. Collins. 1994. Lymphohematopoietic progenitors immortalized by a retroviral vector harboring a dominant-negative retinoic acid receptor can recapitulate lymphoid, myeloid, and erythroid development. Genes & Dev. 8: 2831-2841.
53. Ullrich, A. and J. Schlessinger. 1990. Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203-212.
54. Valius, M. and A. Kazlauskas. 1993. Phospholipase C-γ1 and phosphatidylinositol 3-kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73: 321-334.
55. van der Geer, P. and T. Hunter. 1993. Mutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblasts. EMBO J. 12: 5161-5172.
56. Vojtek, A. and S. Hollenberg. 1995. Ras-Raf interaction: Two-hybrid analysis. Methods Enzymol. 255: 331-342.
57. Vojtek, A.B., S.M. Hollenberg, and J.A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205-214.
58. Walker, J.E., M. Saraste, M.J. Runswick, and N.J. Gay. 1982. Distantly related sequences in the α- and β-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1: 945-951.
59. Yamashita, T., D.L. Barber, Y. Zhu, N. Wu, and A.D. D'Andrea. 1994. The Fanconi anemia polypeptide FACC is localized to the cytoplasm. Proc. Nat. Acad. Sci. 91: 6712-6716.
60. Young, D., M. Riggs, J. Field, A. Vojtek, D. Broek, and M. Wigler. 1989. The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc. Nat. Acad. Sci. 86: 7989-7993.