PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 11, 1999, Pages 6199-6204

  Sun, Hong ^a   Lesche, Ralf ^b   Li, Da Ming ^a   Liliental, Joanna ^b,c   Zhang, Hui ^a   Gao, Jing ^b   Gavrilova, Nadia ^a   Mueller, Brenda ^c   Liu, Xin ^c   Wu, Hong ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; INOSITOL DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE B; PROTEIN P27; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GROWTH RATE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REACTION ANALYSIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EMBRYO; GENES, TUMOR SUPPRESSOR; GENOMIC LIBRARY; IN SITU NICK-END LABELING; KINETICS; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINATION, GENETIC; RESTRICTION MAPPING; SIGNAL TRANSDUCTION; STEM CELLS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 13044305289     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.11.6199     Document Type: Article

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