-
1
-
-
37349080586
-
Global molecular epidemiology of HIV: Understanding the genesis of AIDS pandemic
-
Takebe Y, Uenishi R, Li X. Global molecular epidemiology of HIV: understanding the genesis of AIDS pandemic. Adv. Pharmacol. 56, 1-25 (2008).
-
(2008)
Adv. Pharmacol.
, vol.56
, pp. 1-25
-
-
Takebe, Y.1
Uenishi, R.2
Li, X.3
-
2
-
-
77951783213
-
Tuberculosis as part of the natural history of HIV infection in developing countries
-
Chamie G, Luetkemeyer A, Charlebois E, Havlir DV. Tuberculosis as part of the natural history of HIV infection in developing countries. Clin. Infect. Dis. 50(Suppl. 3), S245-S254 (2010).
-
(2010)
Clin. Infect. Dis.
, vol.50
, Issue.3
-
-
Chamie, G.1
Luetkemeyer, A.2
Charlebois, E.3
Havlir, D.V.4
-
3
-
-
10944253148
-
Cutaneous markers of HIV infection
-
DOI 10.1016/j.clindermatol.2004.07.007, PII S0738081X04001270
-
Rigopoulos D, Paparizos V, Katsambas A. Cutaneous markers of HIV infection. Clin. Dermatol. 22(6), 487-498 (2004). (Pubitemid 40017670)
-
(2004)
Clinics in Dermatology
, vol.22
, Issue.6
, pp. 487-498
-
-
Rigopoulos, D.1
Paparizos, V.2
Katsambas, A.3
-
4
-
-
60549090253
-
Long-term control of HIV by CCR5 Delta32/ Delta32 stem-cell transplantation
-
Hutter G, Nowak D, Mossner M et al. Long-term control of HIV by CCR5 Delta32/ Delta32 stem-cell transplantation. N. Engl. J. Med. 360(7), 692-698 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.7
, pp. 692-698
-
-
Hutter, G.1
Nowak, D.2
Mossner, M.3
-
5
-
-
16044367526
-
The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
-
DOI 10.1038/nm1196-1240
-
Huang Y, Paxton WA, Wolinsky SM et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat. Med. 2(11), 1240-1243 (1996). (Pubitemid 26375409)
-
(1996)
Nature Medicine
, vol.2
, Issue.11
, pp. 1240-1243
-
-
Huang, Y.1
Paxton, W.A.2
Wolinsky, S.M.3
Neumann, A.U.4
Zhang, L.5
He, T.6
Kang, S.7
Ceradini, D.8
Jin, Z.9
Yazdanbakhsh, K.10
Kunstman, K.11
Erickson, D.12
Dragon, E.13
Landau, N.R.14
Phair, J.15
Ho, D.D.16
Koup, R.A.17
-
6
-
-
79954580272
-
Current prospects for RNA interference-based therapies
-
Davidson BL, McCray PB. Current prospects for RNA interference-based therapies. Nat. Rev. Genet. 12(5), 329-340 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, Issue.5
, pp. 329-340
-
-
Davidson, B.L.1
McCray, P.B.2
-
7
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
DOI 10.1038/nature02870
-
Hannon GJ, Rossi JJ. Unlocking the potential of the human genome with RNA interference. Nature 431(7006), 371-378 (2004). (Pubitemid 39265678)
-
(2004)
Nature
, vol.431
, Issue.7006
, pp. 371-378
-
-
Hannon, G.J.1
Rossi, J.J.2
-
8
-
-
34347335707
-
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
-
DOI 10.1128/MCB.00128-07
-
Eulalio A, Behm-Ansmant I, Schweizer D, Izaurralde E. P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol. Cell Biol. 27(11), 3970-3981 (2007). (Pubitemid 47010995)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.11
, pp. 3970-3981
-
-
Eulalio, A.1
Behm-Ansmant, I.2
Schweizer, D.3
Izaurralde, E.4
-
9
-
-
0347444723
-
MicroRNAs: Genomics biogenesis mechanism and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2), 281-297 (2004).
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
12
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
-
DOI 10.1016/j.ymthe.2005.07.524, PII S1525001605011123
-
Li M-J, Kim J, Li S et al. Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolarlocalizing TAR decoy. Mol. Ther. 12(5), 900-909 (2005). (Pubitemid 41614486)
-
(2005)
Molecular Therapy
, vol.12
, Issue.5
, pp. 900-909
-
-
Li, M.-J.1
Kim, J.2
Li, S.3
Zaia, J.4
Yee, J.-K.5
Anderson, J.6
Akkina, R.7
Rossi, J.J.8
-
13
-
-
56349155978
-
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs
-
Aagaard LA, Zhang J, von Eije KJ et al. Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs. Gene Ther. 15(23), 1536-1549 (2008).
-
(2008)
Gene Ther.
, vol.15
, Issue.23
, pp. 1536-1549
-
-
Aagaard, L.A.1
Zhang, J.2
Von Eije, K.J.3
-
14
-
-
77950520528
-
Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV coreceptor CCR5
-
Ehsani A, Saetrom P, Zhang J et al. Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV coreceptor CCR5. Mol. Ther. 18(4), 796-802 (2011).
-
(2011)
Mol. Ther.
, vol.18
, Issue.4
, pp. 796-802
-
-
Ehsani, A.1
Saetrom, P.2
Zhang, J.3
-
15
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
DOI 10.1038/nbt0502-500
-
Lee NS, Dohjima T, Bauer G et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotech. 20(5), 500-505 (2002). (Pubitemid 34495938)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.5
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
Li, H.4
Li, M.-J.5
Ehsani, A.6
Salvaterra, P.7
Rossi, J.8
-
16
-
-
0025882673
-
Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs
-
Heaphy S, Finch JT, Gait MJ, Karn J, Singh M. Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich 'bubble' located within the rev-responsive region of viral mRNAs. Proc. Natl Acad. Sci. USA 88(16), 7366-7370 (1991). (Pubitemid 21915152)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.16
, pp. 7366-7370
-
-
Heaphy, S.1
Finch, J.T.2
Gait, M.J.3
Karn, J.4
Singh, M.5
-
17
-
-
0026601935
-
Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein
-
USA
-
Tiley LS, Malim MH, Tewary HK, Stockley PG, Cullen BR. Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proc. Natl Acad. Sci. USA 89(2), 758-762 (1992).
-
(1992)
Proc. Natl Acad. Sci.
, vol.89
, Issue.2
, pp. 758-762
-
-
Tiley, L.S.1
Malim, M.H.2
Tewary, H.K.3
Stockley, P.G.4
Cullen, B.R.5
-
18
-
-
0024756963
-
A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization
-
Endo S, Kubota S, Siomi H et al. A region of basic amino-acid cluster in HIV-1 Tat protein is essential for trans-acting activity and nucleolar localization. Virus Genes. 3(2), 99-110 (1989).
-
(1989)
Virus Genes.
, vol.3
, Issue.2
, pp. 99-110
-
-
Endo, S.1
Kubota, S.2
Siomi, H.3
-
19
-
-
0025239390
-
Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localization
-
Siomi H, Shida H, Maki M, Hatanaka M. Effects of a highly basic region of human immunodeficiency virus Tat protein on nucleolar localization. J. Virol. 64(4), 1803-1807 (1990). (Pubitemid 20104919)
-
(1990)
Journal of Virology
, vol.64
, Issue.4
, pp. 1803-1807
-
-
Siomi, H.1
Shida, H.2
Maki, M.3
Hatanaka, M.4
-
20
-
-
0029160316
-
The roles of nucleolar structure and function in the subcellular location of the HIV-1 Rev protein
-
Pt 8
-
Dundr M, Leno GH, Hammarskjold ML et al. The roles of nucleolar structure and function in the subcellular location of the HIV-1 Rev protein. J. Cell Sci. 108(Pt 8), 2811-2823 (1995).
-
(1995)
J. Cell Sci.
, vol.108
, pp. 2811-2823
-
-
Dundr, M.1
Leno, G.H.2
Hammarskjold, M.L.3
-
21
-
-
0032506209
-
Analysis of intracellular trafficking and interactions of cytoplasmic HIV-1 Rev mutants in living cells
-
DOI 10.1006/viro.1998.9295
-
Stauber RH, Afonina E, Gulnik S, Erickson J, Pavlakis GN. Analysis of intracellular trafficking and interactions of cytoplasmic HIV-1 Rev mutants in living cells. Virology. 251(1), 38-48 (1998). (Pubitemid 28527717)
-
(1998)
Virology
, vol.251
, Issue.1
, pp. 38-48
-
-
Stauber, R.H.1
Afonina, E.2
Gulnik, S.3
Erickson, J.4
Pavlakis, G.N.5
-
22
-
-
0035091163
-
Ultrastructural localization of the RNA of immunodeficiency viruses using electron microscopy in situ hybridization and in vitro infected lymphocytes
-
DOI 10.1016/S0968-4328(00)00053-6, PII S0968432800000536
-
Canto-Nogues C, Hockley D, Grief C et al. Ultrastructural localization of the RNA of immunodeficiency viruses using electron microscopy in situ hybridization and in vitro infected lymphocytes. Micron. 32(6), 579-589 (2001). (Pubitemid 32247497)
-
(2001)
Micron
, vol.32
, Issue.6
, pp. 579-589
-
-
Canto-Nogues, C.1
Hockley, D.2
Grief, C.3
Ranjbar, S.4
Bootman, J.5
Almond, N.6
Herrera, I.7
-
23
-
-
0032869368
-
The Rev protein is able to transport to the cytoplasm small nucleolar RNAs containing a Rev binding element
-
DOI 10.1017/S1355838299990064
-
Buonomo SB, Michienzi A, De Angelis FG, Bozzoni I. The Rev protein is able to transport to the cytoplasm small nucleolar RNAs containing a Rev binding element. RNA 5(8), 993-1002 (1999). (Pubitemid 29365329)
-
(1999)
RNA
, vol.5
, Issue.8
, pp. 993-1002
-
-
Buonomo, S.B.C.1
Michienzi, A.2
De Angelis, F.G.3
Bozzoni, I.4
-
24
-
-
0037195096
-
A nucleolar TAR decoy inhibitor of HIV-1 replication
-
DOI 10.1073/pnas.212229599
-
Michienzi A, Li S, Zaia JA, Rossi JJ. A nucleolar TAR decoy inhibitor of HIV-1 replication. Proc. Natl Acad. Sci. USA 99(22), 14047-14052 (2002). (Pubitemid 35257622)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.22
, pp. 14047-14052
-
-
Michienzi, A.1
Li, S.2
Zaia, J.A.3
Rossi, J.J.4
-
25
-
-
33748355325
-
A nucleolar localizing Rev binding element inhibits HIV replication
-
Michienzi A, De Angelis FG, Bozzoni I, Rossi JJ. A nucleolar localizing Rev binding element inhibits HIV replication. AIDS Res Ther. 3, 13 (2006).
-
(2006)
AIDS Res Ther.
, vol.3
, pp. 13
-
-
Michienzi, A.1
De Angelis, F.G.2
Bozzoni, I.3
Rossi, J.J.4
-
27
-
-
0034255512
-
Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA
-
DOI 10.1073/pnas.97.16.8955
-
Michienzi A, Cagnon L, Bahner I, Rossi JJ. Ribozyme-mediated inhibition of HIV 1 suggests nucleolar trafficking of HIV-1 RNA. Proc. Natl Acad. Sci. USA 97(16), 8955-8960 (2000). (Pubitemid 30626655)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 8955-8960
-
-
Michienzi, A.1
Cagnon, L.2
Bahner, I.3
Rossi, J.J.4
-
28
-
-
44349160204
-
Use of A U16 snoRNA-containing ribozyme library to identify ribozyme targets in HIV-1
-
DOI 10.1038/mt.2008.54, PII MT200854
-
Unwalla HJ, Li H, Li SY, Abad D, Rossi JJ. Use of a U16 snoRNA-containing ribozyme library to identify ribozyme targets in HIV-1. Mol. Ther. 16(6), 1113-1119 (2008). (Pubitemid 351737077)
-
(2008)
Molecular Therapy
, vol.16
, Issue.6
, pp. 1113-1119
-
-
Unwalla, H.J.1
Li, H.2
Li, S.-Y.3
Abad, D.4
Rossi, J.J.5
-
29
-
-
0033811703
-
Downregulation of the CCR5 b-chemokine receptor and inhibition of HIV-1 infection by stable VA1-ribozyme chimeric transcripts
-
Cagnon L, Rossi JJ. Downregulation of the CCR5 b-chemokine receptor and inhibition of HIV-1 infection by stable VA1-ribozyme chimeric transcripts. Antisense Nucleic Acid Drug Dev. 10(4), 251-261 (2000).
-
(2000)
Antisense Nucleic Acid Drug Dev.
, vol.10
, Issue.4
, pp. 251-261
-
-
Cagnon, L.1
Rossi, J.J.2
-
30
-
-
10744228940
-
Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs
-
DOI 10.1016/S1525-0016(03)00165-5
-
Li MJ, Bauer G, Michienzi A et al. Inhibition of HIV-1 infection by lentiviral vectors expressing Pol III-promoted anti-HIV RNAs. Mol. Ther. 8(2), 196-206 (2003). (Pubitemid 37062830)
-
(2003)
Molecular Therapy
, vol.8
, Issue.2
, pp. 196-206
-
-
Li, M.-J.1
Bauer, G.2
Michienzi, A.3
Yee, J.-K.4
Lee, N.-S.5
Kim, J.6
Li, S.7
Castanotto, D.8
Zaia, J.9
Rossi, J.J.10
-
31
-
-
0037072880
-
Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
-
Botos I, O'Keefe BR, Shenoy SR et al. Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides. J. Biol Chem. 277(37), 34336-34342 (2002).
-
(2002)
J. Biol Chem.
, vol.277
, Issue.37
, pp. 34336-34342
-
-
Botos, I.1
O'Keefe, B.R.2
Shenoy, S.R.3
-
32
-
-
77955365315
-
Actinohivin a broadly neutralizing prokaryotic lectin inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope
-
Hoorelbeke B, Huskens D, Ferir G et al. Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope. Antimicrob. Agents Chemother. 54(8), 3287-3301 (2010).
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, Issue.8
, pp. 3287-3301
-
-
Hoorelbeke, B.1
Huskens, D.2
Ferir, G.3
-
33
-
-
9144270207
-
Inhibition of Human Immunodeficiency Virus Type 1 Entry in Cells Expressing gp41-Derived Peptides
-
DOI 10.1128/JVI.78.2.568-575.2004
-
Egelhofer M, Brandenburg G, Martinius H et al. Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides. J Virol. 78(2), 568-575 (2004). (Pubitemid 38067578)
-
(2004)
Journal of Virology
, vol.78
, Issue.2
, pp. 568-575
-
-
Egelhofer, M.1
Brandenburg, G.2
Martinius, H.3
Schult-Dietrich, P.4
Melikyan, G.5
Kunert, R.6
Baum, C.7
Choi, I.8
Alexandrov, A.9
Von Laer, D.10
-
34
-
-
34248155890
-
HIV gp41 C-terminal heptad repeat contains multifunctional domains: Relation to mechanisms of action of anti-HIV peptides
-
DOI 10.1074/jbc.M609148200
-
Liu S, Jing W, Cheung B et al. HIV gp41 C-terminal heptad repeat contains multifunctional domains. Relation to mechanisms of action of anti-HIV peptides. J. Biol. Chem. 282(13), 9612-9620 (2007). (Pubitemid 47104580)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.13
, pp. 9612-9620
-
-
Liu, S.1
Jing, W.2
Cheung, B.3
Lu, H.4
Sun, J.5
Yan, X.6
Niu, J.7
Farmar, J.8
Wu, S.9
Jiang, S.10
-
35
-
-
77649174985
-
Anti-retroviral activity of TRIM5 a
-
Nakayama EE, Shioda T. Anti-retroviral activity of TRIM5 a. Rev. Med. Virol. 20(2), 77-92 (2010).
-
(2010)
Rev. Med. Virol.
, vol.20
, Issue.2
, pp. 77-92
-
-
Nakayama, E.E.1
Shioda, T.2
-
36
-
-
77954541463
-
Generation of human TRIM5alpha mutants with high HIV-1 restriction activity
-
Pham QT, Bouchard A, Grutter MG, Berthoux L. Generation of human TRIM5alpha mutants with high HIV-1 restriction activity. Gene Ther. 17(7), 859-871 (2010).
-
(2010)
Gene Ther.
, vol.17
, Issue.7
, pp. 859-871
-
-
Pham, Q.T.1
Bouchard, A.2
Grutter, M.G.3
Berthoux, L.4
-
37
-
-
73849124989
-
Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 a protein a CCR5 shRNA and a TAR decoy
-
Anderson JS, Javien J, Nolta JA, Bauer G. Preintegration HIV-1 inhibition by a combination lentiviral vector containing a chimeric TRIM5 a protein, a CCR5 shRNA, and a TAR decoy. Mol. Ther. 17(12), 2103-2114 (2009).
-
(2009)
Mol. Ther.
, vol.17
, Issue.12
, pp. 2103-2114
-
-
Anderson, J.S.1
Javien, J.2
Nolta, J.A.3
Bauer, G.4
-
38
-
-
0032477738
-
Structure-function analysis of integrase interactor 1/hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region
-
DOI 10.1073/pnas.95.3.1120
-
Morozov A, Yung E, Kalpana GV. Structurefunction analysis of integrase interactor 1/ hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region. Proc. Natl Acad. Sci. USA. 95(3), 1120-1125 (1998). (Pubitemid 28124922)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.3
, pp. 1120-1125
-
-
Morozov, A.1
Yung, E.2
Kalpana, G.V.3
-
39
-
-
1242297002
-
Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance
-
DOI 10.1128/JVI.78.5.2222-2231.2004
-
Yung E, Sorin M, Wang EJ et al. Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance. J. Virol. 78(5), 2222-2231 (2004). (Pubitemid 38228915)
-
(2004)
Journal of Virology
, vol.78
, Issue.5
, pp. 2222-2231
-
-
Yung, E.1
Sorin, M.2
Wang, E.-J.3
Perumal, S.4
Ott, D.5
Kalpana, G.V.6
-
40
-
-
0030919846
-
RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication
-
Bonyhadi ML, Moss K, Voytovich A et al. RevM10-expressing T cells derived in vivo from transduced human hematopoietic stem-progenitor cells inhibit human immunodeficiency virus replication. J. Virol. 71(6), 4707-4716 (1997). (Pubitemid 27204163)
-
(1997)
Journal of Virology
, vol.71
, Issue.6
, pp. 4707-4716
-
-
Bonyhadi, M.L.1
Moss, K.2
Voytovich, A.3
Auten, J.4
Kalfoglou, C.5
Plavec, I.6
Forestell, S.7
Su, L.8
Bohnlein, E.9
Kaneshima, H.10
-
41
-
-
0029064110
-
Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro
-
Maciejewski JP, Weichold FF, Young NS et al. Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro. Nat. Med. 1(7), 667-673 (1995).
-
(1995)
Nat. Med.
, vol.1
, Issue.7
, pp. 667-673
-
-
Maciejewski, J.P.1
Weichold, F.F.2
Young, N.S.3
-
42
-
-
0032938325
-
Inhibition of HIV-1 by an anti-integrase single-chain variable fragment (SFv): Delivery by SV40 provides durable protection against HIV-1 and does not require selection
-
DOI 10.1038/sj.gt.3300864
-
BouHamdan M, Duan LX, Pomerantz RJ, Strayer DS. Inhibition of HIV-1 by an anti-integrase single-chain variable fragment (SFv): delivery by SV40 provides durable protection against HIV-1 and does not require selection. Gene Ther. 6(4), 660-666 (1999). (Pubitemid 29192675)
-
(1999)
Gene Therapy
, vol.6
, Issue.4
, pp. 660-666
-
-
BouHamdan, M.1
Duan, L.-X.2
Pomerantz, R.J.3
Strayer, D.S.4
-
43
-
-
0028168145
-
Sequence and structure of V(H) domain from naturally occurring camel heavy chain immunoglobulins lacking light chains
-
Muyldermans S, Atarhouch T, Saldanha J, Barbosa JA, Hamers R. Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains. Protein Eng. 7(9), 1129-1135 (1994). (Pubitemid 24282500)
-
(1994)
Protein Engineering
, vol.7
, Issue.9
, pp. 1129-1135
-
-
Muyldermans, S.1
Atarhouch, T.2
Saldanha, J.3
Barbosa, J.A.R.G.4
Hamers, R.5
-
44
-
-
2942724405
-
Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity
-
DOI 10.1016/j.jmb.2004.04.062, PII S0022283604004759
-
Aires da Silva F, Santa-Marta M, Freitas-Vieira A et al. Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity. J. Mol. Biol. 340(3), 525-542 (2004). (Pubitemid 38797998)
-
(2004)
Journal of Molecular Biology
, vol.340
, Issue.3
, pp. 525-542
-
-
Da Silva, F.A.1
Santa-Marta, M.2
Freitas-Vieira, A.3
Mascarenhas, P.4
Barahona, I.5
Moniz-Pereira, J.6
Gabuzda, D.7
Goncalves, J.8
-
45
-
-
0029931402
-
Fusion with an RNA binding domain to confer target RNA specificity to an RNase: Design and engineering of Tat-RNase h that specifically recognizes and cleaves HIV-1 RNA in vitro
-
DOI 10.1093/nar/24.10.1908
-
Melekhovets YF, Joshi S. Fusion with an RNA binding domain to confer target RNA specificity to an RNase: design and engineering of Tat-RNase H that specifically recognizes and cleaves HIV-1 RNA in vitro. Nucleic Acids Res. 24(10), 1908-1912 (1996). (Pubitemid 26156070)
-
(1996)
Nucleic Acids Research
, vol.24
, Issue.10
, pp. 1908-1912
-
-
Melekhovets, Y.F.1
Joshi, S.2
-
46
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
DOI 10.1038/nature03556
-
Urnov FD, Miller JC, Lee YL et al. Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435(7042), 646-651 (2005). (Pubitemid 40825505)
-
(2005)
Nature
, vol.435
, Issue.7042
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.-L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
47
-
-
46949095221
-
+ T cells by genome editing using zinc-finger nucleases
-
DOI 10.1038/nbt1410, PII NBT1410
-
+ T cells by genome editing using zinc-finger nucleases. Nat. Biotechnol. 26(7), 808-816 (2008). (Pubitemid 351961450)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 808-816
-
-
Perez, E.E.1
Wang, J.2
Miller, J.C.3
Jouvenot, Y.4
Kim, K.A.5
Liu, O.6
Wang, N.7
Lee, G.8
Bartsevich, V.V.9
Lee, Y.-L.10
Guschin, D.Y.11
Rupniewski, I.12
Waite, A.J.13
Carpenito, C.14
Carroll, R.G.15
Orange, J.S.16
Urnov, F.D.17
Rebar, E.J.18
Ando, D.19
Gregory, P.D.20
Riley, J.L.21
Holmes, M.C.22
June, C.H.23
more..
-
49
-
-
34347398120
-
HIV-1 proviral DNA excision using an evolved recombinase
-
DOI 10.1126/science.1141453
-
Sarkar I, Hauber I, Hauber J, Buchholz F. HIV-1 proviral DNA excision using an evolved recombinase. Science. 316(5833), 1912-1915 (2007). (Pubitemid 47025793)
-
(2007)
Science
, vol.316
, Issue.5833
, pp. 1912-1915
-
-
Sarkar, I.1
Hauber, I.2
Hauber, J.3
Buchholz, F.4
-
50
-
-
79960560682
-
Proviral HIV-genome-wide and pol-gene specific zinc finger nucleases: Usability for targeted HIV gene therapy
-
Wayengera M. Proviral HIV-genome-wide and pol-gene specific Zinc Finger Nucleases: Usability for targeted HIV gene therapy. Theor. Biol. Med. Model 8, 26 (2011).
-
(2011)
Theor. Biol. Med. Model
, vol.8
, pp. 26
-
-
Wayengera, M.1
-
51
-
-
79951783813
-
Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI
-
Aubert M, Ryu BY, Banks L et al. Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI. PLoS One 6(2), E16825 (2011).
-
(2011)
PLoS One
, vol.6
, Issue.2
-
-
Aubert, M.1
Ryu, B.Y.2
Banks, L.3
-
52
-
-
78149417692
-
Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5- seronegative persons: A randomized clinical trial HVTN 054
-
Peiperl L, Morgan C, Moodie Z et al. Safety and immunogenicity of a replication-defective adenovirus type 5 HIV vaccine in Ad5- seronegative persons: a randomized clinical trial (HVTN 054).PLoS One 5(10), E13579 (2010).
-
(2010)
PLoS One
, vol.5
, Issue.10
-
-
Peiperl, L.1
Morgan, C.2
Moodie, Z.3
-
53
-
-
33750227671
-
+ T cell responses
-
DOI 10.1002/eji.200636508
-
+ T cell responses. Eur. J. Immunol. 36(10), 2585-2594 (2006). (Pubitemid 44608442)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.10
, pp. 2585-2594
-
-
Ondondo, B.O.1
Yang, H.2
Dong, T.3
Di Gleria, K.4
Suttill, A.5
Conlon, C.6
Brown, D.7
Williams, P.8
Rowland-Jones, S.L.9
Hanke, T.10
McMichael, A.J.11
Dorrell, L.12
-
54
-
-
0033168686
-
+ cells from the bone marrow of human immunodeficiency virus-1-infected children
-
+ cells from the bone marrow of human immunodeficiency virus-1-infected children. Blood. 94(1), 368-371 (1999). (Pubitemid 29300172)
-
(1999)
Blood
, vol.94
, Issue.1
, pp. 368-371
-
-
Kohn, D.B.1
Bauer, G.2
Rice, C.R.3
Rothschild, J.C.4
Carbonaro, D.A.5
Valdez, P.6
Hao, Q.-L.7
Zhou, C.8
Bahner, I.9
Kearns, K.10
Brody, K.11
Fox, S.12
Haden, E.13
Wilson, K.14
Salata, C.15
Dolan, C.16
Wetter, C.17
Aguilar-Cordova, E.18
Church, J.19
-
55
-
-
12144291445
-
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: Myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients
-
DOI 10.1089/104303404322886101
-
Amado RG, Mitsuyasu RT, Rosenblatt JD et al. Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a Phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients. Hum. Gene Ther. 15(3), 251-262 (2004). (Pubitemid 38365914)
-
(2004)
Human Gene Therapy
, vol.15
, Issue.3
, pp. 251-262
-
-
Amado, R.G.1
Mitsuyasu, R.T.2
Rosenblatt, J.D.3
Ngok, F.K.4
Bakker, A.5
Cole, S.6
Chorn, N.7
Lin, L.-S.8
Bristol, G.9
Boyd, M.P.10
Macpherson, J.L.11
Fanning, G.C.12
Todd, A.V.13
Ely, J.A.14
Zack, J.A.15
Symonds, G.P.16
-
56
-
-
20844440241
-
+ cells
-
DOI 10.1016/j.ymthe.2005.02.024, PII S152500160500105X
-
+ cells. Mol. Ther. 12(1), 77-86 (2005). (Pubitemid 40862359)
-
(2005)
Molecular Therapy
, vol.12
, Issue.1
, pp. 77-86
-
-
Podsakoff, G.M.1
Engel, B.C.2
Carbonaro, D.A.3
Choi, C.4
Smogorzewska, E.M.5
Bauer, G.6
Selander, D.7
Csik, S.8
Wilson, K.9
Betts, M.R.10
Koup, R.A.11
Nabel, G.J.12
Bishop, K.13
King, S.14
Schmidt, M.15
Von Kalle, C.16
Church, J.A.17
Kohn, D.B.18
-
58
-
-
77955608799
-
+ cells in patients undergoing transplantation for AIDS-related lymphoma
-
+ cells in patients undergoing transplantation for AIDS-related lymphoma. Sci. Transl. Med. 2(36), 36ra43 (2010).
-
(2010)
Sci. Transl. Med.
, vol.2
, Issue.36
-
-
DiGiusto, D.L.1
Krishnan, A.2
Li, L.3
-
59
-
-
78650735673
-
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo
-
Holt N, Wang J, Kim K et al. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo. Nat. Biotechnol. 28(8), 839-847 (2010).
-
(2010)
Nat. Biotechnol.
, vol.28
, Issue.8
, pp. 839-847
-
-
Holt, N.1
Wang, J.2
Kim, K.3
-
60
-
-
79960047585
-
RNAi-inducing lentiviral vectors for anti-HIV-1 gene therapy
-
Liu YP, Westerink JT, Ter Brake O, Berkhout B. RNAi-inducing lentiviral vectors for anti-HIV-1 gene therapy. Methods Mol. Biol. 721, 293-311 (2011).
-
(2011)
Methods Mol. Biol.
, vol.721
, pp. 293-311
-
-
Liu, Y.P.1
Westerink, J.T.2
Ter Brake, O.3
Berkhout, B.4
-
61
-
-
27944496521
-
Retroviral insertional mutagenesis: Past, present and future
-
DOI 10.1038/sj.onc.1209043, PII 1209043
-
Uren AG, Kool J, Berns A, van Lohuizen M. Retroviral insertional mutagenesis: past, present and future. Oncogene 24(52), 7656-7672 (2005). (Pubitemid 41670669)
-
(2005)
Oncogene
, vol.24
, Issue.52
, pp. 7656-7672
-
-
Uren, A.G.1
Kool, J.2
Berns, A.3
Van Lohuizen, M.4
-
62
-
-
0026654682
-
Human immunodeficiency virus infection of cells arrested in the cell cycle
-
Lewis P, Hensel M, Emerman M. Human immunodeficiency virus infection of cells arrested in the cell cycle. EMBO J. 11(8), 3053-3058 (1992).
-
(1992)
EMBO J.
, vol.11
, Issue.8
, pp. 3053-3058
-
-
Lewis, P.1
Hensel, M.2
Emerman, M.3
-
63
-
-
29144481848
-
Retroviral infection of non-dividing cells: Old and new perspectives
-
DOI 10.1016/j.virol.2005.09.012, PII S0042682205005854
-
Yamashita M, Emerman M. Retroviral infection of non-dividing cells: old and new perspectives. Virology. 344(1), 88-93 (2006). (Pubitemid 41814454)
-
(2006)
Virology
, vol.344
, Issue.1
, pp. 88-93
-
-
Yamashita, M.1
Emerman, M.2
-
64
-
-
0030716959
-
Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors
-
DOI 10.1038/ng1197-314
-
Kafri T, Blomer U, Peterson DA, Gage FH, Verma IM. Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors. Nat. Genet. 17(3), 314-317 (1997). (Pubitemid 27475995)
-
(1997)
Nature Genetics
, vol.17
, Issue.3
, pp. 314-317
-
-
Kafri, T.1
Blomer, U.2
Peterson, D.A.3
Gage, F.H.4
Verma, I.M.5
-
65
-
-
0343851161
-
Development of lentiviral vectors for gene therapy for human diseases
-
Buchschacher GL Jr, Wong-Staal F. Development of lentiviral vectors for gene therapy for human diseases. Blood 95(8), 2499-2504 (2000). (Pubitemid 30210526)
-
(2000)
Blood
, vol.95
, Issue.8
, pp. 2499-2504
-
-
Buchschacher Jr., G.L.1
Wong-Staal, F.2
-
66
-
-
77649273815
-
Recent advances in lentiviral vector development and applications
-
Matrai J, Chuah MK, VandenDriessche T. Recent advances in lentiviral vector development and applications. Mol. Ther. 18(3), 477-490 (2010).
-
(2010)
Mol. Ther.
, vol.18
, Issue.3
, pp. 477-490
-
-
Matrai, J.1
Chuah, M.K.2
VandenDriessche, T.3
-
67
-
-
60649103432
-
Clinical application of lentiviral vectors - Concepts and practice
-
Schambach A, Baum C. Clinical application of lentiviral vectors - concepts and practice. Curr. Gene Ther. 8(6), 474-482 (2008).
-
(2008)
Curr. Gene Ther.
, vol.8
, Issue.6
, pp. 474-482
-
-
Schambach, A.1
Baum, C.2
-
68
-
-
3042773732
-
Transduction of cell lines and primary cells by FIV-packaged HIV vectors
-
DOI 10.1016/j.ymthe.2004.03.019, PII S1525001604001224
-
Morris KV, Gilbert J, Wong-Staal F, Gasmi M, Looney DJ. Transduction of cell lines and primary cells by FIV-packaged HIV vectors. Mol. Ther. 10(1), 181-190 (2004). (Pubitemid 38878160)
-
(2004)
Molecular Therapy
, vol.10
, Issue.1
, pp. 181-190
-
-
Morris, K.V.1
Gilbert, J.2
Wong-Staal, F.3
Gasmi, M.4
Looney, D.J.5
-
69
-
-
27344450815
-
Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1 HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage
-
Strappe PM, Hampton DW, Brown D et al. Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage. Retrovirology 2, 55 (2005).
-
(2005)
Retrovirology
, vol.2
, pp. 55
-
-
Strappe, P.M.1
Hampton, D.W.2
Brown, D.3
-
70
-
-
60649100499
-
Development and applications of non-HIVbased lentiviral vectors in neurological disorders
-
Valori CF, Ning K, Wyles M, Azzouz M. Development and applications of non-HIVbased lentiviral vectors in neurological disorders. Curr. Gene. Ther. 8(6), 406-418 (2008).
-
(2008)
Curr. Gene. Ther.
, vol.8
, Issue.6
, pp. 406-418
-
-
Valori, C.F.1
Ning, K.2
Wyles, M.3
Azzouz, M.4
-
71
-
-
68949187846
-
MRNA nuclear export at a glance
-
Pt 12
-
Carmody SR, Wente SR. mRNA nuclear export at a glance. J Cell Sci. 122(Pt 12), 1933-1937 (2009).
-
(2009)
J Cell Sci.
, vol.122
, pp. 1933-1937
-
-
Carmody, S.R.1
Wente, S.R.2
-
72
-
-
75149196287
-
The mechanism of eukaryotic translation initiation and principles of its regulation
-
Jackson RJ, Hellen CU, Pestova TV. The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev. Mol. Cell Biol. 11(2), 113-127 (2010).
-
(2010)
Nat Rev. Mol. Cell Biol.
, vol.11
, Issue.2
, pp. 113-127
-
-
Jackson, R.J.1
Hellen, C.U.2
Pestova, T.V.3
-
73
-
-
34548332512
-
Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites
-
DOI 10.1261/rna.556107
-
Bradrick SS, Dobrikova EY, Kaiser C, Shveygert M, Gromeier M. Poly(A)-binding protein is differentially required for translation mediated by viral internal ribosome entry sites. RNA 13(9), 1582-1593 (2007). (Pubitemid 47347428)
-
(2007)
RNA
, vol.13
, Issue.9
, pp. 1582-1593
-
-
Bradrick, S.S.1
Dobrikova, E.Y.2
Kaiser, C.3
Shveygert, M.4
Gromeier, M.5
-
74
-
-
85011941667
-
Diverse polyA binding proteins mediate internal translational initiation by a plant viral IRES
-
Marom L, Hen-Avivi S, Pinchasi D et al. Diverse poly(A) binding proteins mediate internal translational initiation by a plant viral IRES. RNA Biol. 6(4), 446-454 (2009).
-
(2009)
RNA Biol.
, vol.6
, Issue.4
, pp. 446-454
-
-
Marom, L.1
Hen-Avivi, S.2
Pinchasi, D.3
-
75
-
-
13644267108
-
Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle
-
DOI 10.1002/jgm.516
-
Brooks AR, Harkins RN, Wang P et al. Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle. J. Gene Med. 6(4), 395-404 (2004). (Pubitemid 40228056)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.4
, pp. 395-404
-
-
Brooks, A.R.1
Harkins, R.N.2
Wang, P.3
Qian, H.S.4
Liu, P.5
Rubanyi, G.M.6
-
76
-
-
33847636745
-
Transgenes delivered by lentiviral vector are suppressed in human embryonic stem cells in a promoter-dependent manner
-
DOI 10.1089/scd.
-
Xia X, Zhang Y, Zieth CR, Zhang SC. Transgenes delivered by lentiviral vector are suppressed in human embryonic stem cells in a promoter-dependent manner. Stem Cells Dev. 16(1), 167-176 (2007). (Pubitemid 46362600)
-
(2007)
Stem Cells and Development
, vol.16
, Issue.1
, pp. 167-176
-
-
Xia, X.1
Zhang, Y.2
Zieth, C.R.3
Zhang, S.-C.4
-
77
-
-
2642673611
-
Reactivation of the previously silenced cytomegalovirus major immediate- early promoter in the mouse liver: Involvement of NFκB
-
Loser P, Jennings GS, Strauss M, Sandig V. Reactivation of the previously silenced cytomegalovirus major immediate-early promoter in the mouse liver: involvement of NFkB. J. Virol. 72(1), 180-190 (1998). (Pubitemid 28048827)
-
(1998)
Journal of Virology
, vol.72
, Issue.1
, pp. 180-190
-
-
Loser, P.1
Jennings, G.S.2
Strauss, M.3
Sandig, V.4
-
78
-
-
0034669932
-
High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors
-
Salmon P, Kindler V, Ducrey O et al. High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors. Blood 96(10), 3392-3398 (2000).
-
(2000)
Blood
, vol.96
, Issue.10
, pp. 3392-3398
-
-
Salmon, P.1
Kindler, V.2
Ducrey, O.3
-
79
-
-
63049099514
-
Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation
-
Veron P, Boutin S, Martin S et al. Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation. J. Transl. Med. 7, 10 (2009).
-
(2009)
J. Transl. Med.
, vol.7
, pp. 10
-
-
Veron, P.1
Boutin, S.2
Martin, S.3
-
80
-
-
0034783643
-
Systematic determination of the packaging limit of lentiviral vectors
-
DOI 10.1089/104303401753153947
-
Kumar M, Keller B, Makalou N, Sutton RE. Systematic determination of the packaging limit of lentiviral vectors. Hum. Gene Ther. 12(15), 1893-1905 (2001). (Pubitemid 32947232)
-
(2001)
Human Gene Therapy
, vol.12
, Issue.15
, pp. 1893-1905
-
-
Kumar, M.1
Keller, B.2
Makalou, N.3
Sutton, R.E.4
-
81
-
-
77957337971
-
Large double copy vectors are functional but show a size-dependent decline in transduction efficiency
-
Bos TJ, De Bruyne E, Van Lint S, Heirman C, Vanderkerken K. Large double copy vectors are functional but show a size-dependent decline in transduction efficiency. J. Biotechnol. 150(1), 37-40 (2010).
-
(2010)
J. Biotechnol.
, vol.150
, Issue.1
, pp. 37-40
-
-
Bos, T.J.1
De Bruyne, E.2
Van Lint, S.3
Heirman, C.4
Vanderkerken, K.5
-
82
-
-
0034322159
-
Lentiviral vectors for enhanced gene expression in human hematopoietic cells
-
Ramezani A, Hawley TS, Hawley RG. Lentiviral vectors for enhanced gene expression in human hematopoietic cells. Mol. Ther. 2(5), 458-469 (2000).
-
(2000)
Mol. Ther.
, vol.2
, Issue.5
, pp. 458-469
-
-
Ramezani, A.1
Hawley, T.S.2
Hawley, R.G.3
-
83
-
-
0029872366
-
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice
-
DOI 10.1093/nar/24.9.1787
-
Schorpp M, Jager R, Schellander K et al. The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice. Nucleic Acids Res. 24(9), 1787-1788 (1996). (Pubitemid 26137941)
-
(1996)
Nucleic Acids Research
, vol.24
, Issue.9
, pp. 1787-1788
-
-
Schorpp, M.1
Jager, R.2
Schellander, K.3
Schenkel, J.4
Wagner, E.F.5
Weiher, H.6
Angel, P.7
-
84
-
-
79551686692
-
Selective nuclear export mechanism of small RNAs
-
Lee SJ, Jiko C, Yamashita E, Tsukihara T. Selective nuclear export mechanism of small RNAs. Curr. Opin. Struct. Biol. 21(1), 101-108 (2011).
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, Issue.1
, pp. 101-108
-
-
Lee, S.J.1
Jiko, C.2
Yamashita, E.3
Tsukihara, T.4
-
85
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
DOI 10.1038/nature04791, PII NATURE04791
-
Grimm D, Streetz KL, Jopling CL et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441(7092), 537-541 (2006). (Pubitemid 44050158)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
86
-
-
34250357616
-
Optimization and characterization of tRNA-shRNA expression constructs
-
DOI 10.1093/nar/gkm103
-
Scherer LJ, Frank R, Rossi JJ. Optimization and characterization of tRNA-shRNA expression constructs. Nucleic Acids Res. 35(8), 2620-2628 (2007). (Pubitemid 47073675)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.8
, pp. 2620-2628
-
-
Scherer, L.J.1
Frank, R.2
Rossi, J.J.3
-
87
-
-
44349164025
-
Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
-
DOI 10.1093/nar/gkn109
-
Liu YP, Haasnoot J, ter Brake O, Berkhout B, Konstantinova P. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res. 36(9), 2811-2824 (2008). (Pubitemid 351737175)
-
(2008)
Nucleic Acids Research
, vol.36
, Issue.9
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
Ter Brake, O.3
Berkhout, B.4
Konstantinova, P.5
-
88
-
-
80052830258
-
Molecular strategies to design an escape-proof antiviral therapy
-
Berkhout B, Sanders RW. Molecular strategies to design an escape-proof antiviral therapy. Antiviral Res. 92(1), 7-14 (2011).
-
(2011)
Antiviral Res.
, vol.92
, Issue.1
, pp. 7-14
-
-
Berkhout, B.1
Sanders, R.W.2
-
89
-
-
0028969816
-
Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression
-
Koenig S, Conley AJ, Brewah YA et al. Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. Nat. Med. 1(4), 330-336 (1995).
-
(1995)
Nat. Med.
, vol.1
, Issue.4
, pp. 330-336
-
-
Koenig, S.1
Conley, A.J.2
Brewah, Y.A.3
-
90
-
-
0142124143
-
Human immunodeficiency virus type 1 escape from rna interference
-
DOI 10.1128/JVI.77.21.11531-11535.2003
-
Boden D, Pusch O, Lee F, Tucker L, Ramratnam B. Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 77(21), 11531-11535 (2003). (Pubitemid 37271651)
-
(2003)
Journal of Virology
, vol.77
, Issue.21
, pp. 11531-11535
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Ramratnam, B.5
-
91
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from rna interference- mediated inhibition
-
DOI 10.1128/JVI.78.5.2601-2605.2004
-
Das AT, Brummelkamp TR, Westerhout EM et al. Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 78(5), 2601-2605 (2004). (Pubitemid 38228957)
-
(2004)
Journal of Virology
, vol.78
, Issue.5
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
Vink, M.4
Madiredjo, M.5
Bernards, R.6
Berkhout, B.7
-
92
-
-
30344474936
-
Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs
-
DOI 10.1128/JVI.80.2.571-577.2006
-
Sabariegos R, Gimenez-Barcons M, Tapia N, Clotet B, Martinez MA. Sequence homology required by human immunodeficiency virus type 1 to escape from short interfering RNAs. J. Virol. 80(2), 571-577 (2006). (Pubitemid 43062869)
-
(2006)
Journal of Virology
, vol.80
, Issue.2
, pp. 571-577
-
-
Sabariegos, R.1
Gimenez-Barcons, M.2
Tapia, N.3
Clotet, B.4
Martinez, M.A.5
-
93
-
-
13844320402
-
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
-
DOI 10.1093/nar/gki220
-
Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B. HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 33(2), 796-804 (2005). (Pubitemid 40361009)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.2
, pp. 796-804
-
-
Westerhout, E.M.1
Ooms, M.2
Vink, M.3
Das, A.T.4
Berkhout, B.5
-
94
-
-
33748438866
-
Optimization and Functional Effects of Stable Short Hairpin RNA Expression in Primary Human Lymphocytes via Lentiviral Vectors
-
DOI 10.1016/j.ymthe.2006.05.015, PII S1525001606002139
-
An DS, Qin FX, Auyeung VC et al. Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. Mol. Ther. 14(4), 494-504 (2006). (Pubitemid 44339392)
-
(2006)
Molecular Therapy
, vol.14
, Issue.4
, pp. 494-504
-
-
An, D.S.1
Qin, F.X.-F.2
Auyeung, V.C.3
Mao, S.H.4
Kung, S.K.P.5
Baltimore, D.6
Chen, I.S.Y.7
-
95
-
-
33745108790
-
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
-
DOI 10.1038/nbt1216, PII N1216
-
Montini E, Cesana D, Schmidt M et al. Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration. Nat. Biotechnol. 24(6), 687-696 (2006). (Pubitemid 43882120)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.6
, pp. 687-696
-
-
Montini, E.1
Cesana, D.2
Schmidt, M.3
Sanvito, F.4
Ponzoni, M.5
Bartholomae, C.6
Sergi, L.S.7
Benedicenti, F.8
Ambrosi, A.9
Di Serio, C.10
Doglioni, C.11
Von Kalle, C.12
Naldini, L.13
-
96
-
-
35349024379
-
Immune responses to lentiviral vectors
-
DOI 10.2174/156652307782151515
-
Follenzi A, Santambrogio L, Annoni A. Immune responses to lentiviral vectors. Curr. Gene Ther. 7(5), 306-315 (2007). (Pubitemid 47595773)
-
(2007)
Current Gene Therapy
, vol.7
, Issue.5
, pp. 306-315
-
-
Follenzi, A.1
Santambrogio, L.2
Annoni, A.3
-
97
-
-
52649181650
-
Restricted transgene persistence after lentiviral vector-mediated fetal gene transfer in the pregnant rabbit model
-
Moreno R, Rosal M, Martinez I et al. Restricted transgene persistence after lentiviral vector-mediated fetal gene transfer in the pregnant rabbit model. J. Gene Med. 10(9), 951-964 (2008).
-
(2008)
J. Gene Med.
, vol.10
, Issue.9
, pp. 951-964
-
-
Moreno, R.1
Rosal, M.2
Martinez, I.3
-
98
-
-
73949157699
-
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance
-
Annoni A, Brown BD, Cantore A et al. In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance. Blood 114(25), 5152-5161 (2009).
-
(2009)
Blood
, vol.114
, Issue.25
, pp. 5152-5161
-
-
Annoni, A.1
Brown, B.D.2
Cantore, A.3
-
99
-
-
80052766645
-
An unbiased genome-wide analysis of zinc-finger nuclease specificity
-
Gabriel R, Lombardo A, Arens A et al. An unbiased genome-wide analysis of zinc-finger nuclease specificity. Nat. Biotechnol. 29(9), 816-823 (2011).
-
(2011)
Nat. Biotechnol.
, vol.29
, Issue.9
, pp. 816-823
-
-
Gabriel, R.1
Lombardo, A.2
Arens, A.3
-
100
-
-
80052293623
-
Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection
-
Pattanayak V, Ramirez CL, Joung JK, Liu DR. Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection. Nat. Methods. 8(9), 765-770 (2011).
-
(2011)
Nat. Methods.
, vol.8
, Issue.9
, pp. 765-770
-
-
Pattanayak, V.1
Ramirez, C.L.2
Joung, J.K.3
Liu, D.R.4
-
101
-
-
77954842706
-
Gene regulatory networks governing haematopoietic stem cell development and identity
-
Pimanda JE, Gottgens B. Gene regulatory networks governing haematopoietic stem cell development and identity. Int. J. Dev. Biol. 54(6-7), 1201-1211 (2011).
-
(2011)
Int. J. Dev. Biol.
, vol.54
, Issue.6-7
, pp. 1201-1211
-
-
Pimanda, J.E.1
Gottgens, B.2
-
102
-
-
60649084807
-
Strategies for targeting lentiviral vectors
-
Frecha C, Szecsi J, Cosset FL, Verhoeyen E. Strategies for targeting lentiviral vectors. Curr. Gene Ther. 8(6), 449-460 (2008).
-
(2008)
Curr. Gene Ther.
, vol.8
, Issue.6
, pp. 449-460
-
-
Frecha, C.1
Szecsi, J.2
Cosset, F.L.3
Verhoeyen, E.4
-
103
-
-
77957552436
-
Advances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy
-
Frecha C, Levy C, Cosset FL, Verhoeyen E. Advances in the field of lentivector-based transduction of T and B lymphocytes for gene therapy. Mol. Ther. 18(10), 1748-1757 (2010).
-
(2010)
Mol. Ther.
, vol.18
, Issue.10
, pp. 1748-1757
-
-
Frecha, C.1
Levy, C.2
Cosset, F.L.3
Verhoeyen, E.4
-
104
-
-
0034669933
-
In vivo kinetics of murine hemopoietic stem cells
-
Abkowitz JL, Golinelli D, Harrison DE, Guttorp P. In vivo kinetics of murine hemopoietic stem cells. Blood 96(10), 3399-3405 (2000).
-
(2000)
Blood
, vol.96
, Issue.10
, pp. 3399-3405
-
-
Abkowitz, J.L.1
Golinelli, D.2
Harrison, D.E.3
Guttorp, P.4
-
105
-
-
34547102215
-
- severe combined immunodeficiency-repopulating cells by intra-bone marrow injection
-
DOI 10.1634/stemcells.2006-0727
-
Kimura T, Asada R, Wang J et al. Identification of long-term repopulating potential of human cord blood-derived CD34-flt3- severe combined immunodeficiency-repopulating cells by intra-bone marrow injection. Stem Cells 25(6), 1348-1355 (2007). (Pubitemid 47106001)
-
(2007)
Stem Cells
, vol.25
, Issue.6
, pp. 1348-1355
-
-
Kimura, T.1
Asada, R.2
Wang, J.3
Kimura, T.4
Morioka, M.5
Matsui, K.6
Kobayashi, K.7
Henmi, K.8
Imai, S.9
Kita, M.10
Tsuji, T.11
Sasaki, Y.12
Ikehara, S.13
Sonoda, Y.14
-
106
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JC et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 469(7330), 362-367 (2011).
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
-
107
-
-
77949424638
-
Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O6-methylguanine-DNA methyltransferaseP140K
-
Maier P, Spier I, Laufs S et al. Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).Gene Ther. 17(3), 389-399 (2010).
-
(2010)
Gene Ther.
, vol.17
, Issue.3
, pp. 389-399
-
-
Maier, P.1
Spier, I.2
Laufs, S.3
-
108
-
-
34447331660
-
6-methylguanine-DNA methyltransferase in hematopoietic cells
-
DOI 10.1016/j.dnarep.2007.03.017, PII S156878640700136X
-
Schambach A, Baum C. Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells. DNA Repair (Amst.) 6(8), 1187-1196 (2007). (Pubitemid 47058401)
-
(2007)
DNA Repair
, vol.6
, Issue.8
, pp. 1187-1196
-
-
Schambach, A.1
Baum, C.2
-
109
-
-
70349832417
-
Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL
-
E4
-
Nishino T, Miyaji K, Ishiwata N et al. Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL. Exp. Hematol. 37(11), 1364-1377.E4 (2009).
-
(2009)
Exp. Hematol.
, vol.37
, Issue.11
, pp. 1364-1377
-
-
Nishino, T.1
Miyaji, K.2
Ishiwata, N.3
-
110
-
-
0028914587
-
Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors
-
van der Loo JC, Ploemacher RE. Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors. Blood 85(9), 2598-2606 (1995).
-
(1995)
Blood
, vol.85
, Issue.9
, pp. 2598-2606
-
-
Van Der Loo, J.C.1
Ploemacher, R.E.2
-
111
-
-
19444386119
-
Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion
-
DOI 10.1182/blood-2004-11-4418
-
Zhang CC, Lodish HF. Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion. Blood 105(11), 4314-4320 (2005). (Pubitemid 40723656)
-
(2005)
Blood
, vol.105
, Issue.11
, pp. 4314-4320
-
-
Cheng, C.Z.1
Lodish, H.F.2
|