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Volumn 35, Issue 8, 2007, Pages 2620-2628

Optimization and characterization of tRNA-shRNA expression constructs

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE TRANSFER RNA; RIBONUCLEASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; AMINOACYL TRANSFER RNA; REV PROTEIN; TRANSACTIVATOR PROTEIN; TRNA, LYSINE; TRNA, LYSINE-; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 34250357616     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm103     Document Type: Article
Times cited : (39)

References (51)
  • 1
    • 33645144814 scopus 로고    scopus 로고
    • Lentiviral-mediated delivery of siRNAs for antiviral therapy
    • Morris, K.V. and Rossi, J.J. (2006) Lentiviral-mediated delivery of siRNAs for antiviral therapy. Gene Ther., 13, 553-558.
    • (2006) Gene Ther , vol.13 , pp. 553-558
    • Morris, K.V.1    Rossi, J.J.2
  • 2
    • 33646848909 scopus 로고    scopus 로고
    • RNAi as a treatment for HIV-1 infection
    • Rossi, J.J. (2006) RNAi as a treatment for HIV-1 infection. Biotechniques, 40, s25-s29.
    • (2006) Biotechniques , vol.40
    • Rossi, J.J.1
  • 4
    • 18744399611 scopus 로고    scopus 로고
    • Does RNA interference have a future as a treatment for HIV-1 induced disease?
    • Cullen, B.R. (2005) Does RNA interference have a future as a treatment for HIV-1 induced disease? AIDS Rev., 7, 22-25.
    • (2005) AIDS Rev , vol.7 , pp. 22-25
    • Cullen, B.R.1
  • 5
    • 27644592822 scopus 로고    scopus 로고
    • RNAi as an antiviral therapy
    • Bagasra, O. (2005) RNAi as an antiviral therapy. Expert. Opin. Biol. Ther., 5, 1463-1474.
    • (2005) Expert. Opin. Biol. Ther , vol.5 , pp. 1463-1474
    • Bagasra, O.1
  • 6
    • 18144403552 scopus 로고    scopus 로고
    • Molecular strategies to inhibit HIV-1 replication
    • Nielsen, M.H., Pedersen, F.S. and Kjems, J. (2005) Molecular strategies to inhibit HIV-1 replication. Retrovirology, 2, 10.
    • (2005) Retrovirology , vol.2 , pp. 10
    • Nielsen, M.H.1    Pedersen, F.S.2    Kjems, J.3
  • 7
    • 29244448022 scopus 로고    scopus 로고
    • siRNA, miRNA and HIV: Promises and challenges
    • Yeung, M.L., Bennasser, Y., Le, S.Y. and Jeang, K.T. (2005) siRNA, miRNA and HIV: Promises and challenges. Cell Res., 15, 935-946.
    • (2005) Cell Res , vol.15 , pp. 935-946
    • Yeung, M.L.1    Bennasser, Y.2    Le, S.Y.3    Jeang, K.T.4
  • 9
    • 33748438866 scopus 로고    scopus 로고
    • Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors
    • An, D.S., Qin, F.X., Auyeung, V.C., Mao, S.H., Kung, S.K., Baltimore, D. and Chen, I.S. (2006) Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors, Mol. Ther., 14, 494-504.
    • (2006) Mol. Ther , vol.14 , pp. 494-504
    • An, D.S.1    Qin, F.X.2    Auyeung, V.C.3    Mao, S.H.4    Kung, S.K.5    Baltimore, D.6    Chen, I.S.7
  • 10
    • 0036256430 scopus 로고    scopus 로고
    • Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
    • Lee, N.S., Dohjima, T., Bauer, G., Li, H., Li, M.J., Ehsani, A., Salvaterra, P. and Rossi, J. (2002) Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol., 20, 500-505.
    • (2002) Nat. Biotechnol , vol.20 , pp. 500-505
    • Lee, N.S.1    Dohjima, T.2    Bauer, G.3    Li, H.4    Li, M.J.5    Ehsani, A.6    Salvaterra, P.7    Rossi, J.8
  • 11
    • 4444237030 scopus 로고    scopus 로고
    • Rapid assessment of anti-HIV siRNA efficacy using PCR-derived Pol III shRNA cassettes
    • Scherer, L.J., Yildiz, Y., Kim, J., Cagnon, L., Heale, B. and Rossi, J.J. (2004) Rapid assessment of anti-HIV siRNA efficacy using PCR-derived Pol III shRNA cassettes. Mol. Ther., 10, 597-603.
    • (2004) Mol. Ther , vol.10 , pp. 597-603
    • Scherer, L.J.1    Yildiz, Y.2    Kim, J.3    Cagnon, L.4    Heale, B.5    Rossi, J.J.6
  • 13
    • 0030854739 scopus 로고    scopus 로고
    • tRNAscan-SE: A program for improved detection of transfer RNA genes in genomic sequence
    • Lowe, T.M. and Eddy, S.R. (1997) tRNAscan-SE: A program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res., 25, 955-964.
    • (1997) Nucleic Acids Res , vol.25 , pp. 955-964
    • Lowe, T.M.1    Eddy, S.R.2
  • 14
    • 0037439213 scopus 로고    scopus 로고
    • tRNA transfers to the limelight
    • Hopper, A.K. and Phizicky, E.M. (2003) tRNA transfers to the limelight. Genes Dev., 17, 162-180.
    • (2003) Genes Dev , vol.17 , pp. 162-180
    • Hopper, A.K.1    Phizicky, E.M.2
  • 15
    • 0033057704 scopus 로고    scopus 로고
    • The 3′ end CCA of mature tRNA is an antideterminant for eukaryotic 3′-tRNase
    • Mohan, A., Whyte, S., Wang, X., Nashimoto, M. and Levinger, L. (1999) The 3′ end CCA of mature tRNA is an antideterminant for eukaryotic 3′-tRNase. RNA, 5, 245-256.
    • (1999) RNA , vol.5 , pp. 245-256
    • Mohan, A.1    Whyte, S.2    Wang, X.3    Nashimoto, M.4    Levinger, L.5
  • 16
    • 0030754921 scopus 로고    scopus 로고
    • Distribution of both lengths and 5′ terminal nucleotides of mammalian pre-tRNA 3′ trailers reflects properties of 3′ processing endoribonuclease
    • Nashimoto, M. (1997) Distribution of both lengths and 5′ terminal nucleotides of mammalian pre-tRNA 3′ trailers reflects properties of 3′ processing endoribonuclease. Nucleic Acids Res., 25, 1148-1154.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1148-1154
    • Nashimoto, M.1
  • 17
    • 33646872034 scopus 로고    scopus 로고
    • Residues in two homology blocks on the amino side of the tRNase Z His domain contribute unexpectedly to pre-tRNA 3′ end processing
    • Zareen, N., Hopkinson, A. and Levinger, L. (2006) Residues in two homology blocks on the amino side of the tRNase Z His domain contribute unexpectedly to pre-tRNA 3′ end processing. RNA, 12, 1104-1115.
    • (2006) RNA , vol.12 , pp. 1104-1115
    • Zareen, N.1    Hopkinson, A.2    Levinger, L.3
  • 18
    • 0028009774 scopus 로고
    • Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses
    • Chen, B.K., Saksela, K., Andino, R. and Baltimore, D. (1994) Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses. J. Virol., 68, 654-660.
    • (1994) J. Virol , vol.68 , pp. 654-660
    • Chen, B.K.1    Saksela, K.2    Andino, R.3    Baltimore, D.4
  • 19
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • Connor, R.I., Chen, B.K., Choe, S. and Landau, N.R. (1995) Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology, 206, 935-944.
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Chen, B.K.2    Choe, S.3    Landau, N.R.4
  • 20
    • 33745166320 scopus 로고    scopus 로고
    • RNase P: Interface of the RNA and protein worlds
    • Evans, D., Marquez, S.M. and Pace, N.R. (2006) RNase P: Interface of the RNA and protein worlds. Trends Biochem. Sci., 31, 333-341.
    • (2006) Trends Biochem. Sci , vol.31 , pp. 333-341
    • Evans, D.1    Marquez, S.M.2    Pace, N.R.3
  • 21
    • 0036865184 scopus 로고    scopus 로고
    • RNase P RNA-mediated catalysis
    • Kirsebom, L.A. (2002) RNase P RNA-mediated catalysis. Biochem. Soc. Trans., 30, 1153-1158.
    • (2002) Biochem. Soc. Trans , vol.30 , pp. 1153-1158
    • Kirsebom, L.A.1
  • 22
    • 0036210354 scopus 로고    scopus 로고
    • Human ribonuclease P: Subunits, function, and intranuclear localization
    • Jarrous, N. (2002) Human ribonuclease P: Subunits, function, and intranuclear localization. RNA, 8, 1-7.
    • (2002) RNA , vol.8 , pp. 1-7
    • Jarrous, N.1
  • 23
    • 0035997350 scopus 로고    scopus 로고
    • Eukaryotic ribonuclease P: A plurality of ribonucleoprotein enzymes
    • Xiao, S., Scott, F., Fierke, C.A. and Engelke, D.R. (2002) Eukaryotic ribonuclease P: A plurality of ribonucleoprotein enzymes. Annu. Rev. Biochem., 71, 165-189.
    • (2002) Annu. Rev. Biochem , vol.71 , pp. 165-189
    • Xiao, S.1    Scott, F.2    Fierke, C.A.3    Engelke, D.R.4
  • 24
    • 29044449835 scopus 로고    scopus 로고
    • The tRNase Z family of proteins: Physiological functions, substrate specificity and structural properties
    • Vogel, A., Schilling, O., Spath, B. and Marchfelder, A. (2005) The tRNase Z family of proteins: Physiological functions, substrate specificity and structural properties. Biol. Chem., 386, 1253-1264.
    • (2005) Biol. Chem , vol.386 , pp. 1253-1264
    • Vogel, A.1    Schilling, O.2    Spath, B.3    Marchfelder, A.4
  • 25
    • 6044249065 scopus 로고    scopus 로고
    • Mitochondrial tRNA 3′ end metabolism and human disease
    • Levinger, L., Morl, M. and Florentz, C. (2004) Mitochondrial tRNA 3′ end metabolism and human disease. Nucleic Acids Res., 32, 5430-5441.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5430-5441
    • Levinger, L.1    Morl, M.2    Florentz, C.3
  • 26
    • 0035094698 scopus 로고    scopus 로고
    • The final cut
    • The importance of tRNA 3′-processing
    • Morl, M. and Marchfelder, A. (2001) The final cut. The importance of tRNA 3′-processing. EMBO Rep., 2, 17-20.
    • (2001) EMBO Rep , vol.2 , pp. 17-20
    • Morl, M.1    Marchfelder, A.2
  • 27
    • 6944236106 scopus 로고    scopus 로고
    • tRNA maturation: RNA polymerization without a nucleic acid template
    • Weiner, A.M. (2004) tRNA maturation: RNA polymerization without a nucleic acid template. Curr. Biol., 14, R883-R885.
    • (2004) Curr. Biol , vol.14
    • Weiner, A.M.1
  • 28
    • 32644447756 scopus 로고    scopus 로고
    • Post-transcriptional nucleotide modification and alternative folding of RNA
    • Helm, M. (2006) Post-transcriptional nucleotide modification and alternative folding of RNA. Nucleic Acids Res., 34, 721-733.
    • (2006) Nucleic Acids Res , vol.34 , pp. 721-733
    • Helm, M.1
  • 29
    • 7444241391 scopus 로고    scopus 로고
    • Regulation of RNA function by aminoacylation and editing?
    • Geslain, R. and Ribas de Pouplana, L. (2004) Regulation of RNA function by aminoacylation and editing? Trends Genet., 20, 604-610.
    • (2004) Trends Genet , vol.20 , pp. 604-610
    • Geslain, R.1    Ribas de Pouplana, L.2
  • 30
    • 30744466880 scopus 로고    scopus 로고
    • Modified view of tRNA: Stability amid sequence diversity
    • Engelke, D.R. and Hopper, A.K. (2006) Modified view of tRNA: Stability amid sequence diversity. Mol. Cell., 21, 144-145.
    • (2006) Mol. Cell , vol.21 , pp. 144-145
    • Engelke, D.R.1    Hopper, A.K.2
  • 31
    • 26044435441 scopus 로고    scopus 로고
    • Recent progress of structural biology of tRNA processing and modification
    • Nakanishi, K. and Nureki, O. (2005) Recent progress of structural biology of tRNA processing and modification. Mol. Cells., 19 157-166.
    • (2005) Mol. Cells , vol.19 , pp. 157-166
    • Nakanishi, K.1    Nureki, O.2
  • 33
    • 0037013852 scopus 로고    scopus 로고
    • Assigning a function to a conserved group of proteins: The tRNA 3′-processing enzymes
    • Schiffer, S., Rosch, S. and Marchfelder, A. (2002) Assigning a function to a conserved group of proteins: The tRNA 3′-processing enzymes. EMBO J., 21, 2769-2777.
    • (2002) EMBO J , vol.21 , pp. 2769-2777
    • Schiffer, S.1    Rosch, S.2    Marchfelder, A.3
  • 34
    • 0038750928 scopus 로고    scopus 로고
    • A candidate prostate cancer susceptibility gene encodes tRNA 3′ processing endoribonuclease
    • Takaku, H., Minagawa, A., Takagi, M. and Nashimoto, M. (2003) A candidate prostate cancer susceptibility gene encodes tRNA 3′ processing endoribonuclease. Nucleic Acids Res., 31, 2272-2278.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2272-2278
    • Takaku, H.1    Minagawa, A.2    Takagi, M.3    Nashimoto, M.4
  • 35
    • 33645234546 scopus 로고    scopus 로고
    • Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure
    • Yan, H., Zareen, N. and Levinger, L. (2006) Naturally occurring mutations in human mitochondrial pre-tRNASer(UCN) can affect the transfer ribonuclease Z cleavage site, processing kinetics, and substrate secondary structure. J. Biol. Chem., 281, 3926-3935.
    • (2006) J. Biol. Chem , vol.281 , pp. 3926-3935
    • Yan, H.1    Zareen, N.2    Levinger, L.3
  • 37
    • 1542298923 scopus 로고    scopus 로고
    • A pathogenesis-associated mutation in human mitochondrial tRNALeu(UUR) leads to reduced 3′-end processing and CCA addition
    • Levinger, L., Oestreich, I., Florentz, C. and Morl, M. (2004) A pathogenesis-associated mutation in human mitochondrial tRNALeu(UUR) leads to reduced 3′-end processing and CCA addition. J. Mol. Biol. 337, 535-544.
    • (2004) J. Mol. Biol , vol.337 , pp. 535-544
    • Levinger, L.1    Oestreich, I.2    Florentz, C.3    Morl, M.4
  • 38
    • 0037388028 scopus 로고    scopus 로고
    • Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3′ end processing efficiency in vitro
    • Levinger, L., Giege, R. and Florentz, C. (2003) Pathology-related substitutions in human mitochondrial tRNA(Ile) reduce precursor 3′ end processing efficiency in vitro. Nucleic Acids Res., 31, 1904-1912.
    • (2003) Nucleic Acids Res , vol.31 , pp. 1904-1912
    • Levinger, L.1    Giege, R.2    Florentz, C.3
  • 39
    • 0035497972 scopus 로고    scopus 로고
    • In vitro 3′-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness
    • Levinger, L., Jacobs, O. and James, M. (2001) In vitro 3′-end endonucleolytic processing defect in a human mitochondrial tRNA(Ser(UCN)) precursor with the U7445C substitution, which causes non-syndromic deafness. Nucleic Acids Res., 29, 4334-4340.
    • (2001) Nucleic Acids Res , vol.29 , pp. 4334-4340
    • Levinger, L.1    Jacobs, O.2    James, M.3
  • 40
    • 0034725035 scopus 로고    scopus 로고
    • Anomalous RNA substrates for mammalian tRNA 3′ processing endoribonuclease
    • Nashimoto, M. (2000) Anomalous RNA substrates for mammalian tRNA 3′ processing endoribonuclease. FEBS Lett., 472, 179-186.
    • (2000) FEBS Lett , vol.472 , pp. 179-186
    • Nashimoto, M.1
  • 41
    • 0033735040 scopus 로고    scopus 로고
    • Search for characteristic structural features of mammalian mitochondrial tRNAs
    • Helm, M., Brule, H., Friede, D., Giege, R., Putz, D. and Florentz, C. (2000) Search for characteristic structural features of mammalian mitochondrial tRNAs. RNA, 6, 1356-1379.
    • (2000) RNA , vol.6 , pp. 1356-1379
    • Helm, M.1    Brule, H.2    Friede, D.3    Giege, R.4    Putz, D.5    Florentz, C.6
  • 42
    • 0032103908 scopus 로고    scopus 로고
    • RNA heptamers that direct RNA cleavage by mammalian tRNA 3′ processing endoribonuclease
    • Nashimoto, M., Geary, S., Tamura, M. and Kaspar, R. (1998) RNA heptamers that direct RNA cleavage by mammalian tRNA 3′ processing endoribonuclease. Nucleic Acids Res., 26, 2565-2572.
    • (1998) Nucleic Acids Res , vol.26 , pp. 2565-2572
    • Nashimoto, M.1    Geary, S.2    Tamura, M.3    Kaspar, R.4
  • 43
    • 0042161920 scopus 로고    scopus 로고
    • Intracellular mRNA cleavage by 3′ tRNase under the direction of 2′-O-methyl RNA heptamers
    • Tamura, M., Nashimoto, C., Miyake, N., Daikuhara, Y., Ochi, K. and Nashimoto, M. (2003) Intracellular mRNA cleavage by 3′ tRNase under the direction of 2′-O-methyl RNA heptamers. Nucleic Acids Res., 31, 4354-4360.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4354-4360
    • Tamura, M.1    Nashimoto, C.2    Miyake, N.3    Daikuhara, Y.4    Ochi, K.5    Nashimoto, M.6
  • 44
    • 13744255355 scopus 로고    scopus 로고
    • Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL
    • Habu, Y., Miyano-Kurosaki, N., Kitano, M., Endo, Y., Yukita, M., Ohira, S., Takaku, H. and Nashimoto, M. (2005) Inhibition of HIV-1 gene expression by retroviral vector-mediated small-guide RNAs that direct specific RNA cleavage by tRNase ZL. Nucleic Acids Res., 33, 235-243.
    • (2005) Nucleic Acids Res , vol.33 , pp. 235-243
    • Habu, Y.1    Miyano-Kurosaki, N.2    Kitano, M.3    Endo, Y.4    Yukita, M.5    Ohira, S.6    Takaku, H.7    Nashimoto, M.8
  • 45
    • 0041317121 scopus 로고    scopus 로고
    • RNA cleavage by a mammalian tRNA 3′ processing endoribonuclease (3′tRNase) reduces HIV-1 expression
    • Yukita, M., Kitano, M., Miyano-Kurosaki, N., Takeuchi, H., Nashimoto, M. and Takaku, H. (2002) RNA cleavage by a mammalian tRNA 3′ processing endoribonuclease (3′tRNase) reduces HIV-1 expression. Nucleic Acids Res. Suppl., (Supp 2), 297-298.
    • (2002) Nucleic Acids Res. Suppl , Issue.SUPP 2 , pp. 297-298
    • Yukita, M.1    Kitano, M.2    Miyano-Kurosaki, N.3    Takeuchi, H.4    Nashimoto, M.5    Takaku, H.6
  • 46
    • 3042775552 scopus 로고    scopus 로고
    • A novel 4-base-recognizing RNA cutter that can remove the single 3′ terminal nucleotides from RNA molecules
    • Takaku, H., Minagawa, A., Takagi, M. and Nashimoto, M. (2004) A novel 4-base-recognizing RNA cutter that can remove the single 3′ terminal nucleotides from RNA molecules. Nucleic Acids Res., 32, e9l.
    • (2004) Nucleic Acids Res , vol.32
    • Takaku, H.1    Minagawa, A.2    Takagi, M.3    Nashimoto, M.4
  • 48
    • 0037440160 scopus 로고    scopus 로고
    • Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
    • Kawasaki, H. and Taira, K. (2003) Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res., 31, 700-707.
    • (2003) Nucleic Acids Res , vol.31 , pp. 700-707
    • Kawasaki, H.1    Taira, K.2
  • 49
    • 23844436723 scopus 로고    scopus 로고
    • Construction of a functional transporter analysis system using MDR1 knockdown Caco-2 cells
    • Watanabe, T., Onuki, R., Yamashita, S., Taira, K. and Sugiyama, Y. (2005) Construction of a functional transporter analysis system using MDR1 knockdown Caco-2 cells. Pharm Res., 22, 1287-1293.
    • (2005) Pharm Res , vol.22 , pp. 1287-1293
    • Watanabe, T.1    Onuki, R.2    Yamashita, S.3    Taira, K.4    Sugiyama, Y.5
  • 50
    • 33344477448 scopus 로고    scopus 로고
    • Genomics of microRNA
    • Kim, V.N. and Nam, J.W. (2006) Genomics of microRNA. Trends Genet, 22, 165-173.
    • (2006) Trends Genet , vol.22 , pp. 165-173
    • Kim, V.N.1    Nam, J.W.2
  • 51
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the drosha-DGCR8 complex
    • Han, J., Lee, Y., Yeom, K.H., Nam, J.W., Heo, I., Rhee, J.K., Sohn, S.Y., Cho,Y., Zhang, B.T. et al. (2006) Molecular basis for the recognition of primary microRNAs by the drosha-DGCR8 complex. Cell 125, 887-901.
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Nam, J.W.4    Heo, I.5    Rhee, J.K.6    Sohn, S.Y.7    Cho, Y.8    Zhang, B.T.9


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