Rational design of micro-RNA-like bifunctional siRNAs targeting HIV and the HIV Coreceptor CCR5

Molecular Therapy

Volumn 18, Issue 4, 2010, Pages 796-802

  Ehsani, Ali ^a   Saetrom, Pål ^b,c   Zhang, Jane ^d   Alluin, Jessica ^a   Li, Haitang ^a   Snøve Jr, Ola ^a,b   Aagaard, Lars ^a   Rossi, John J ^a,d  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^c Interagon AS   (Norway)

^d Irell and Manella Graduate School of Biological Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; COMPLEMENTARY RNA; MESSENGER RNA; MICRORNA; SMALL INTERFERING RNA;

3' UNTRANSLATED REGION; ARTICLE; BASE PAIRING; CELL CULTURE; CONTROLLED STUDY; GENOME; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NUCLEOTIDE SEQUENCE; RNA CLEAVAGE; RNA TRANSLATION; VIRUS REPLICATION;

CELL LINE; GENE THERAPY; HIV; HIV INFECTIONS; HUMANS; MICRORNAS; PROTEIN BIOSYNTHESIS; RECEPTORS, CCR5; RNA, MESSENGER; RNA, SMALL INTERFERING; VIRUS REPLICATION;

EID: 77950520528     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2009.321     Document Type: Article

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