Ex vivo expansion of human hematopoietic stem cells by a small-molecule agonist of c-MPL

Experimental Hematology

Volumn 37, Issue 11, 2009, Pages

  Nishino, Taito ^a   Miyaji, Katsuaki ^a   Ishiwata, Norihisa ^a   Arai, Kazutaka ^a   Yui, Makiko ^b,c   Asai, Yasuyuki ^b   Nakauchi, Hiromitsu ^d   Iwama, Atsushi ^c  

^a NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

^b ReproCELL Inc   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 [[2 [1 [5 (3,4 DICHLOROPHENYL) 4 HYDROXYTHIOPHEN 3 YL]ETHYLIDENE]HYDRAZINYL]CARBONYL] N [(1 METHYL 1H IMIDAZOL 4 YL)METHYL]THIOPHENE 2 CARBOXAMIDE; CD34 ANTIGEN; CD38 ANTIGEN; CYTOKINE RECEPTOR AGONIST; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NR 101; STAT3 PROTEIN; STAT5 PROTEIN; THROMBOPOIETIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL ASSAY; CELL COUNT; CELL ISOLATION; COLONY FORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; EX VIVO STUDY; FLOW CYTOMETRY; GENE ACTIVATION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; HUMAN CELL; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INDUCTION; SEVERE COMBINED IMMUNODEFICIENCY; STEM CELL EXPANSION; UMBILICAL CORD BLOOD;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; CELLS, CULTURED; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOKINE RECEPTOR COMMON BETA SUBUNIT; DNA, COMPLEMENTARY; DRUG EVALUATION, PRECLINICAL; FETAL BLOOD; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERLEUKIN-3 RECEPTOR ALPHA SUBUNIT; LEUKEMIA, MYELOID; MICE; MICE, INBRED NOD; MICE, SCID; RADIATION CHIMERA; RECEPTORS, ERYTHROPOIETIN; RECEPTORS, THROMBOPOIETIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; THROMBOPOIESIS; THROMBOPOIETIN;

EID: 70349832417     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exphem.2009.09.001     Document Type: Article

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