-
1
-
-
0027595949
-
The basic science of gene therapy
-
Mulligan, R.C. The basic science of gene therapy. Science 260, 926-932 (1993).
-
(1993)
Science
, vol.260
, pp. 926-932
-
-
Mulligan, R.C.1
-
2
-
-
0028875936
-
Transfer of genes to humans: Early lessons and obstacles to success
-
Crystal, R.G. Transfer of genes to humans: early lessons and obstacles to success. Science 270, 404-410 (1995).
-
(1995)
Science
, vol.270
, pp. 404-410
-
-
Crystal, R.G.1
-
3
-
-
0029134946
-
Gene therapy - Promises, pitfalls and prognosis
-
Leiden, J.M. Gene therapy - promises, pitfalls and prognosis. N. Engl. J. Med. 333, 871-673 (1995).
-
(1995)
N. Engl. J. Med.
, vol.333
, pp. 871-1673
-
-
Leiden, J.M.1
-
4
-
-
0030928619
-
Gene therapy: Promises, problems and prospects
-
Verma, I.M. & Somia, N. Gene therapy: promises, problems and prospects. Nature 389, 239-242 (1997).
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
5
-
-
0029993858
-
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector
-
Maldini, L., Blomer, U., Gage, F., Trono, D. & Verma, I. Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc. Natl. Acad. Sci. USA 93, 11382-11388 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11382-11388
-
-
Maldini, L.1
Blomer, U.2
Gage, F.3
Trono, D.4
Verma, I.5
-
6
-
-
0029996147
-
In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
-
Naldini, L. et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267 (1996).
-
(1996)
Science
, vol.272
, pp. 263-267
-
-
Naldini, L.1
-
7
-
-
1842411367
-
Highly efficient and sustained gene transfer in adult neurons with a lentiviral vector
-
Blömer, U. et al. Highly efficient and sustained gene transfer in adult neurons with a lentiviral vector. J. Virol. 71, 6641-6649 (1997).
-
(1997)
J. Virol.
, vol.71
, pp. 6641-6649
-
-
Blömer, U.1
-
8
-
-
0027228422
-
Vesicular stomatitis virus G protein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
-
Burns, J.C., Friedman, T., Driever, W., Burrascano, M. & Yii, J.-K. Vesicular stomatitis virus G protein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90, 8033-8037 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 8033-8037
-
-
Burns, J.C.1
Friedman, T.2
Driever, W.3
Burrascano, M.4
Yii, J.-K.5
-
9
-
-
0030931963
-
Stable and efficient gene transfer into the retina using a lentiviral vector
-
Miyoshi, H., Takahashi, M., Gage, F.H. & Verma, I.M. Stable and efficient gene transfer into the retina using a lentiviral vector. Proc. Natl. Acad. Sci. USA 94, 10319-10323 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10319-10323
-
-
Miyoshi, H.1
Takahashi, M.2
Gage, F.H.3
Verma, I.M.4
-
10
-
-
0028134961
-
Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing post-damage age
-
Peterson, D.A., Lucidi-Phillipi, C.A., Eagle, K.L. & Gage, F.H. Perforant path damage results in progressive neuronal death and somal atrophy in layer II of entorhinal cortex and functional impairment with increasing post-damage age. J. Neurosci. 14, 6872-6885 (1994).
-
(1994)
J. Neurosci.
, vol.14
, pp. 6872-6885
-
-
Peterson, D.A.1
Lucidi-Phillipi, C.A.2
Eagle, K.L.3
Gage, F.H.4
-
11
-
-
0026349206
-
Systemic delivery of recombinant proteins by genetically modified myoplasts
-
Barr, E. & Leiden, J.M. Systemic delivery of recombinant proteins by genetically modified myoplasts. Science 254, 1507-1509 (1991).
-
(1991)
Science
, vol.254
, pp. 1507-1509
-
-
Barr, E.1
Leiden, J.M.2
-
12
-
-
0026335995
-
Systemic delivery of human growth hormone by injection of genetically engineered myoblasts
-
Dhawan, J. et al. Systemic delivery of human growth hormone by injection of genetically engineered myoblasts. Science 254, 1509-1512 (1991).
-
(1991)
Science
, vol.254
, pp. 1509-1512
-
-
Dhawan, J.1
-
13
-
-
0026486612
-
Gene therapy via primary myoblasts: Long-term expression of factor IX protein following transplantation in vivo
-
Dai, Y., Roman, M., Naviaux, R.K. & Verma, I.M. Gene therapy via primary myoblasts: Long-term expression of factor IX protein following transplantation in vivo. Proc. Natl. Acad. Sci. USA 89, 10892-10895 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10892-10895
-
-
Dai, Y.1
Roman, M.2
Naviaux, R.K.3
Verma, I.M.4
-
14
-
-
0028934815
-
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: Tolerization of factor IX and vector antigens allows for long-term expression
-
Dai, Y. et al. Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. Proc. Natl. Acad. Sci. USA 92, 1401-1405 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1401-1405
-
-
Dai, Y.1
-
15
-
-
0025976935
-
Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
-
Palmer, T.D., Rosman, G.J., Osborne, W.R.A. & Miller, A.D. Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc. Natl. Acad. Sci. USA 88, 1330-1334 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1330-1334
-
-
Palmer, T.D.1
Rosman, G.J.2
Osborne, W.R.A.3
Miller, A.D.4
-
16
-
-
0025753128
-
Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants
-
Scharfmann, R., Axelrod, J.H. & Verma, I.M. Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants. Proc. Natl. Acad. Sci. USA 88, 4626-4630 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4626-4630
-
-
Scharfmann, R.1
Axelrod, J.H.2
Verma, I.M.3
-
17
-
-
0028484704
-
MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
-
Yang, Y., Ertl, J. & Wilson, J.M. MHC class I-restricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses. Immunity 1, 433-442 (1994).
-
(1994)
Immunity
, vol.1
, pp. 433-442
-
-
Yang, Y.1
Ertl, J.2
Wilson, J.M.3
-
18
-
-
0028937785
-
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses
-
Yang, Y., Li, Q., Ertl, H. & Wilson, J. Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses. J. Virol. 69, 2004-2015 (1995).
-
(1995)
J. Virol.
, vol.69
, pp. 2004-2015
-
-
Yang, Y.1
Li, Q.2
Ertl, H.3
Wilson, J.4
-
19
-
-
0028195026
-
Construction and in vitro properties of HIV-1 mutants with deletions in "non-essential" genes
-
Gibbs, J.S., Regier, D.A. & Desrosiers, R.C. Construction and in vitro properties of HIV-1 mutants with deletions in "non-essential" genes. AIDS Res. Hum. Retroviruses 10, 343-350 (1994).
-
(1994)
AIDS Res. Hum. Retroviruses
, vol.10
, pp. 343-350
-
-
Gibbs, J.S.1
Regier, D.A.2
Desrosiers, R.C.3
-
20
-
-
0025017950
-
The human immunodeficiency virus type 2 Vpr genes is essential for productive infection of human macrophages
-
Hattori, N. et al. The human immunodeficiency virus type 2 Vpr genes is essential for productive infection of human macrophages. Proc Natl. Acad. Sci. USA 87, 8080-8084 (1990).
-
(1990)
Proc Natl. Acad. Sci. USA
, vol.87
, pp. 8080-8084
-
-
Hattori, N.1
-
21
-
-
0028239060
-
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells
-
Heinzinger, N.K. et al. The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells. Proc. Natl. Acad. Sci. USA 91, 7311-7315 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7311-7315
-
-
Heinzinger, N.K.1
|