메뉴 건너뛰기




Volumn 150, Issue 1, 2010, Pages 37-40

Large double copy vectors are functional but show a size-dependent decline in transduction efficiency

Author keywords

Double copy vector; Lentiviral vector

Indexed keywords

DOUBLE COPY VECTOR; LENTIVIRAL VECTOR; TRANSDUCTION EFFICIENCY; TRANSGENE; TRANSGENICS;

EID: 77957337971     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2010.07.010     Document Type: Article
Times cited : (21)

References (15)
  • 1
    • 34548791721 scopus 로고    scopus 로고
    • Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element
    • Arumugam P.I., Scholes J., Perelman N., Xia P., Yee J.K., Malik P. Improved human beta-globin expression from self-inactivating lentiviral vectors carrying the chicken hypersensitive site-4 (cHS4) insulator element. Mol. Ther. 2007, 15:1863-1871.
    • (2007) Mol. Ther. , vol.15 , pp. 1863-1871
    • Arumugam, P.I.1    Scholes, J.2    Perelman, N.3    Xia, P.4    Yee, J.K.5    Malik, P.6
  • 2
    • 0035025888 scopus 로고    scopus 로고
    • A quantitative assay for HIV DNA integration in vivo
    • Butler S.L., Hansen M.S., Bushman F.D. A quantitative assay for HIV DNA integration in vivo. Nat. Med. 2001, 7:631-634.
    • (2001) Nat. Med. , vol.7 , pp. 631-634
    • Butler, S.L.1    Hansen, M.S.2    Bushman, F.D.3
  • 3
    • 77949424881 scopus 로고    scopus 로고
    • Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors
    • Maetzig T., Galla M., Brugman M.H., Loew R., Baum C., Schambach A. Mechanisms controlling titer and expression of bidirectional lentiviral and gammaretroviral vectors. Gene Ther. 2010, 17:400-411.
    • (2010) Gene Ther. , vol.17 , pp. 400-411
    • Maetzig, T.1    Galla, M.2    Brugman, M.H.3    Loew, R.4    Baum, C.5    Schambach, A.6
  • 4
    • 0027085782 scopus 로고
    • A model of multiple myeloma: culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse
    • Manning L.S., Berger J.D., O'Donoghue H.L., Sheridan G.N., Claringbold P.G., Turner J.H. A model of multiple myeloma: culture of 5T33 murine myeloma cells and evaluation of tumorigenicity in the C57BL/KaLwRij mouse. Br. J. Cancer 1992, 66:1088-1093.
    • (1992) Br. J. Cancer , vol.66 , pp. 1088-1093
    • Manning, L.S.1    Berger, J.D.2    O'Donoghue, H.L.3    Sheridan, G.N.4    Claringbold, P.G.5    Turner, J.H.6
  • 5
  • 6
    • 61949341072 scopus 로고    scopus 로고
    • Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants
    • Nielsen T.T., Jakobsson J., Rosenqvist N., Lundberg C. Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants. BMC Biotechnol. 2009, 9:13.
    • (2009) BMC Biotechnol. , vol.9 , pp. 13
    • Nielsen, T.T.1    Jakobsson, J.2    Rosenqvist, N.3    Lundberg, C.4
  • 7
    • 0034296940 scopus 로고    scopus 로고
    • Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes
    • Salmon P., Oberholzer J., Occhiodoro T., Morel P., Lou J., Trono D. Reversible immortalization of human primary cells by lentivector-mediated transfer of specific genes. Mol. Ther. 2000, 2:404-414.
    • (2000) Mol. Ther. , vol.2 , pp. 404-414
    • Salmon, P.1    Oberholzer, J.2    Occhiodoro, T.3    Morel, P.4    Lou, J.5    Trono, D.6
  • 8
    • 34249298695 scopus 로고    scopus 로고
    • Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors
    • Schambach A., Galla M., Maetzig T., Loew R., Baum C. Improving transcriptional termination of self-inactivating gamma-retroviral and lentiviral vectors. Mol. Ther. 2007, 15:1167-1173.
    • (2007) Mol. Ther. , vol.15 , pp. 1167-1173
    • Schambach, A.1    Galla, M.2    Maetzig, T.3    Loew, R.4    Baum, C.5
  • 9
  • 10
  • 11
    • 69949150240 scopus 로고    scopus 로고
    • Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3′LTR
    • Urbinati F., Arumugam P., Higashimoto T., Perumbeti A., Mitts K., Xia P., Malik P. Mechanism of reduction in titers from lentivirus vectors carrying large inserts in the 3′LTR. Mol. Ther. 2009, 17:1527-1536.
    • (2009) Mol. Ther. , vol.17 , pp. 1527-1536
    • Urbinati, F.1    Arumugam, P.2    Higashimoto, T.3    Perumbeti, A.4    Mitts, K.5    Xia, P.6    Malik, P.7
  • 12
    • 33745384405 scopus 로고    scopus 로고
    • A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication
    • Westerhout E.M., Vink M., Haasnoot P.C., Das A.T., Berkhout B. A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication. Mol. Ther. 2006, 14:268-275.
    • (2006) Mol. Ther. , vol.14 , pp. 268-275
    • Westerhout, E.M.1    Vink, M.2    Haasnoot, P.C.3    Das, A.T.4    Berkhout, B.5
  • 13
    • 33747778686 scopus 로고    scopus 로고
    • Tuning silence: conditional systems for RNA interference
    • Wiznerowicz M., Szulc J., Trono D. Tuning silence: conditional systems for RNA interference. Nat. Methods 2006, 3:682-688.
    • (2006) Nat. Methods , vol.3 , pp. 682-688
    • Wiznerowicz, M.1    Szulc, J.2    Trono, D.3
  • 14
    • 0032978712 scopus 로고    scopus 로고
    • Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors
    • Zufferey R., Donello J.E., Trono D., Hope T.J. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 1999, 73:2886-2892.
    • (1999) J. Virol. , vol.73 , pp. 2886-2892
    • Zufferey, R.1    Donello, J.E.2    Trono, D.3    Hope, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.