-
1
-
-
0036806311
-
Evolution of protein kinase signaling from yeast to man
-
Manning G., et al. Evolution of protein kinase signaling from yeast to man. Trends Biochem. Sci. 2002, 27:514-520.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 514-520
-
-
Manning, G.1
-
2
-
-
20444383859
-
Protein phosphorylation in signaling-50 years and counting
-
Pawson T., Scott J.D. Protein phosphorylation in signaling-50 years and counting. Trends Biochem. Sci. 2005, 30:286-290.
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 286-290
-
-
Pawson, T.1
Scott, J.D.2
-
3
-
-
34548660854
-
Prolyl cis-trans isomerization as a molecular timer
-
Lu K.P., et al. Prolyl cis-trans isomerization as a molecular timer. Nat. Chem. Biol. 2007, 3:619-629.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 619-629
-
-
Lu, K.P.1
-
4
-
-
35448945269
-
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
-
Lu K.P., Zhou X.Z. The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease. Nat. Rev. Mol. Cell Biol. 2007, 8:904-916.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 904-916
-
-
Lu, K.P.1
Zhou, X.Z.2
-
5
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
Lu K.P., et al. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 1996, 380:544-547.
-
(1996)
Nature
, vol.380
, pp. 544-547
-
-
Lu, K.P.1
-
6
-
-
0040017910
-
Function of WW domains as phosphoserine- or phosphothreonine-binding modules
-
Lu P.J., et al. Function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science 1999, 283:1325-1328.
-
(1999)
Science
, vol.283
, pp. 1325-1328
-
-
Lu, P.J.1
-
7
-
-
0008233581
-
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent
-
Ranganathan R., et al. Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell 1997, 89:875-886.
-
(1997)
Cell
, vol.89
, pp. 875-886
-
-
Ranganathan, R.1
-
8
-
-
0031438929
-
Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism
-
Yaffe M.B. Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism. Science 1997, 278:1957-1960.
-
(1997)
Science
, vol.278
, pp. 1957-1960
-
-
Yaffe, M.B.1
-
9
-
-
79953127123
-
5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72
-
5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72. J. Biol. Chem. 2011, 286:5717-5726.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5717-5726
-
-
Werner-Allen, J.W.1
-
10
-
-
0033638180
-
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
-
Zhou X.Z., et al. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Mol. Cell 2000, 6:873-883.
-
(2000)
Mol. Cell
, vol.6
, pp. 873-883
-
-
Zhou, X.Z.1
-
11
-
-
0037022355
-
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes
-
Liou Y.C. Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:1335-1340.
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 1335-1340
-
-
Liou, Y.C.1
-
12
-
-
0043069764
-
Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration
-
Liou Y.C., et al. Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration. Nature 2003, 424:556-561.
-
(2003)
Nature
, vol.424
, pp. 556-561
-
-
Liou, Y.C.1
-
13
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
Lu P.J., et al. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 1999, 399:784-788.
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.J.1
-
14
-
-
0034840950
-
Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC
-
Ryo A., et al. Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC. Nat. Cell Biol. 2001, 3:793-801.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 793-801
-
-
Ryo, A.1
-
15
-
-
0347955360
-
Regulation of NF-κB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
-
Ryo A., et al. Regulation of NF-κB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell 2003, 12:1413-1426.
-
(2003)
Mol. Cell
, vol.12
, pp. 1413-1426
-
-
Ryo, A.1
-
16
-
-
0037073713
-
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage
-
Wulf G.M. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J. Biol. Chem. 2002, 277:47976-47979.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47976-47979
-
-
Wulf, G.M.1
-
17
-
-
0035796405
-
Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1
-
Wulf G.M., et al. Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1. EMBO J. 2001, 20:3459-3472.
-
(2001)
EMBO J.
, vol.20
, pp. 3459-3472
-
-
Wulf, G.M.1
-
18
-
-
18644384283
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
-
Zacchi P., et al. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 2002, 419:853-857.
-
(2002)
Nature
, vol.419
, pp. 853-857
-
-
Zacchi, P.1
-
19
-
-
18644384688
-
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
-
Zheng H., et al. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 2002, 419:849-853.
-
(2002)
Nature
, vol.419
, pp. 849-853
-
-
Zheng, H.1
-
20
-
-
79954456974
-
Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function
-
Lee T.H., et al. Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function. Mol. Cell 2011, 42:147-159.
-
(2011)
Mol. Cell
, vol.42
, pp. 147-159
-
-
Lee, T.H.1
-
21
-
-
0037169479
-
Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function
-
Lu P.J., et al. Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function. J. Biol. Chem. 2002, 277:2381-2384.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2381-2384
-
-
Lu, P.J.1
-
22
-
-
0036315162
-
PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells
-
Ryo A., et al. PIN1 is an E2F target gene essential for Neu/Ras-induced transformation of mammary epithelial cells. Mol. Cell. Biol. 2002, 22:5281-5295.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5281-5295
-
-
Ryo, A.1
-
23
-
-
0035676154
-
IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry
-
You H., et al. IGF-1 induces Pin1 expression in promoting cell cycle S-phase entry. J. Cell. Biochem. 2002, 84:211-216.
-
(2002)
J. Cell. Biochem.
, vol.84
, pp. 211-216
-
-
You, H.1
-
24
-
-
80053304845
-
Peptidyl-prolyl cis-trans isomerase Pin1 in aging, cancer and Alzheimer's disease
-
Lee T.H., et al. Peptidyl-prolyl cis-trans isomerase Pin1 in aging, cancer and Alzheimer's disease. Expert Rev. Mol. Med. 2011, 13:e21.
-
(2011)
Expert Rev. Mol. Med.
, vol.13
-
-
Lee, T.H.1
-
25
-
-
0020022916
-
Mechanisms of intracellular protein breakdown
-
Hershko A., Ciechanover A. Mechanisms of intracellular protein breakdown. Annu. Rev. Biochem. 1982, 51:335-364.
-
(1982)
Annu. Rev. Biochem.
, vol.51
, pp. 335-364
-
-
Hershko, A.1
Ciechanover, A.2
-
26
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock K.L., et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 1994, 78:761-771.
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
-
27
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart C.M. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 2001, 70:503-533.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
28
-
-
33745156511
-
Ubiquitin and SUMO systems in the regulation of mitotic checkpoints
-
Gutierrez G.J., Ronai Z. Ubiquitin and SUMO systems in the regulation of mitotic checkpoints. Trends Biochem. Sci. 2006, 31:324-332.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 324-332
-
-
Gutierrez, G.J.1
Ronai, Z.2
-
29
-
-
0037462424
-
Cdc4 ubiquitin ligase
-
Cdc4 ubiquitin ligase. Cell 2003, 112:243-256.
-
(2003)
Cell
, vol.112
, pp. 243-256
-
-
Orlicky, S.1
-
30
-
-
33947140574
-
Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?
-
Balastik M., et al. Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?. Biochim. Biophys. Acta 2007, 1772:422-429.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, pp. 422-429
-
-
Balastik, M.1
-
31
-
-
39349085931
-
Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function
-
Esnault S., et al. Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function. Crit. Rev. Immunol. 2008, 28:45-60.
-
(2008)
Crit. Rev. Immunol.
, vol.28
, pp. 45-60
-
-
Esnault, S.1
-
32
-
-
34848907217
-
Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1
-
Lippens G., et al. Molecular mechanisms of the phospho-dependent prolyl cis/trans isomerase Pin1. FEBS J. 2007, 274:5211-5222.
-
(2007)
FEBS J.
, vol.274
, pp. 5211-5222
-
-
Lippens, G.1
-
33
-
-
34247490735
-
PIN1, the cell cycle and cancer
-
Yeh E.S., Means A.R. PIN1, the cell cycle and cancer. Nat. Rev. Cancer 2007, 7:381-388.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 381-388
-
-
Yeh, E.S.1
Means, A.R.2
-
34
-
-
1942533406
-
Prevalent overexpression of prolyl isomerase Pin1 in human cancers
-
Bao L., et al. Prevalent overexpression of prolyl isomerase Pin1 in human cancers. Am. J. Pathol. 2004, 164:1727-1737.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1727-1737
-
-
Bao, L.1
-
35
-
-
0028308702
-
Cyclin D1 protein expression and function in human breast cancer
-
Bartkova J., et al. Cyclin D1 protein expression and function in human breast cancer. Int. J. Cancer 1994, 57:353-361.
-
(1994)
Int. J. Cancer
, vol.57
, pp. 353-361
-
-
Bartkova, J.1
-
36
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O., McCormick F. β-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999, 398:422-426.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
37
-
-
0032533225
-
Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
-
Diehl J.A., et al. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 1998, 12:3499-3511.
-
(1998)
Genes Dev.
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
-
38
-
-
0030916209
-
Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
-
Diehl J.A., et al. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev. 1997, 11:957-972.
-
(1997)
Genes Dev.
, vol.11
, pp. 957-972
-
-
Diehl, J.A.1
-
39
-
-
0025788098
-
Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73
-
Smeal T., et al. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 1991, 354:494-496.
-
(1991)
Nature
, vol.354
, pp. 494-496
-
-
Smeal, T.1
-
40
-
-
77952423398
-
Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML
-
Pulikkan J.A., et al. Elevated PIN1 expression by C/EBPα-p30 blocks C/EBPα-induced granulocytic differentiation through c-Jun in AML. Leukemia 2010, 24:914-923.
-
(2010)
Leukemia
, vol.24
, pp. 914-923
-
-
Pulikkan, J.A.1
-
41
-
-
0036234124
-
MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis
-
Craig R.W. MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis. Leukemia 2002, 16:444-454.
-
(2002)
Leukemia
, vol.16
, pp. 444-454
-
-
Craig, R.W.1
-
42
-
-
34347350211
-
Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization
-
Ding Q., et al. Degradation of Mcl-1 by β-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol. Cell. Biol. 2007, 27:4006-4017.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4006-4017
-
-
Ding, Q.1
-
43
-
-
51049101063
-
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer
-
Ding Q., et al. Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res. 2008, 68:6109-6117.
-
(2008)
Cancer Res.
, vol.68
, pp. 6109-6117
-
-
Ding, Q.1
-
44
-
-
38549132438
-
Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 Cells
-
Reineke E.L., et al. Degradation of the tumor suppressor PML by Pin1 contributes to the cancer phenotype of breast cancer MDA-MB-231 Cells. Mol. Cell. Biol. 2008, 28:997-1006.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 997-1006
-
-
Reineke, E.L.1
-
45
-
-
0037351048
-
Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer
-
Ryo A., et al. Prolyl isomerase Pin1: a catalyst for oncogenesis and a potential therapeutic target in cancer. J. Cell Sci. 2003, 116:773-783.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 773-783
-
-
Ryo, A.1
-
46
-
-
2342526543
-
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
-
Yeh E., et al. A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells. Nat. Cell Biol. 2004, 6:308-318.
-
(2004)
Nat. Cell Biol.
, vol.6
, pp. 308-318
-
-
Yeh, E.1
-
47
-
-
62049085035
-
The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc
-
Arnold H.K., et al. The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc. EMBO J. 2009, 28:500-512.
-
(2009)
EMBO J.
, vol.28
, pp. 500-512
-
-
Arnold, H.K.1
-
48
-
-
33644850537
-
The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability
-
Yeh E.S., et al. The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability. J. Biol. Chem. 2006, 281:241-251.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 241-251
-
-
Yeh, E.S.1
-
49
-
-
33144488245
-
Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis
-
Mark M., et al. Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis. Annu. Rev. Pharmacol. Toxicol. 2006, 46:451-480.
-
(2006)
Annu. Rev. Pharmacol. Toxicol.
, vol.46
, pp. 451-480
-
-
Mark, M.1
-
50
-
-
59149091122
-
Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARα and PML-RARα
-
Gianni M., et al. Inhibition of the peptidyl-prolyl-isomerase Pin1 enhances the responses of acute myeloid leukemia cells to retinoic acid via stabilization of RARα and PML-RARα. Cancer Res. 2009, 69:1016-1026.
-
(2009)
Cancer Res.
, vol.69
, pp. 1016-1026
-
-
Gianni, M.1
-
51
-
-
12844275363
-
The peptidyl-prolyl isomerase Pin1 regulates phospho-Ser retinoic acid receptor α stability
-
Brondani V., et al. The peptidyl-prolyl isomerase Pin1 regulates phospho-Ser retinoic acid receptor α stability. Biochem. Biophys. Res. Commun. 2005, 328:6-13.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.328
, pp. 6-13
-
-
Brondani, V.1
-
52
-
-
77951227828
-
Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1
-
Reineke E.L., et al. Promyelocytic leukemia protein controls cell migration in response to hydrogen peroxide and insulin-like growth factor-1. J. Biol. Chem. 2010, 285:9485-9492.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 9485-9492
-
-
Reineke, E.L.1
-
53
-
-
27144480681
-
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1)
-
Yi P., et al. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol. Cell. Biol. 2005, 25:9687-9699.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 9687-9699
-
-
Yi, P.1
-
54
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
-
Siegel P.M., Massague J. Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer. Nat. Rev. Cancer 2003, 3:807-821.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
55
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa T., et al. Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 2001, 276:12477-12480.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
-
56
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation
-
Kavsak P., et al. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation. Mol. Cell 2000, 6:1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
-
57
-
-
33846688094
-
Balancing BMP signaling through integrated inputs into the Smad1 linker
-
Sapkota G., et al. Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol. Cell 2007, 25:441-454.
-
(2007)
Mol. Cell
, vol.25
, pp. 441-454
-
-
Sapkota, G.1
-
58
-
-
65249175171
-
Pin1 down-regulates transforming growth factor-β (TGF-β) signaling by inducing degradation of Smad proteins
-
Nakano A., et al. Pin1 down-regulates transforming growth factor-β (TGF-β) signaling by inducing degradation of Smad proteins. J. Biol. Chem. 2009, 284:6109-6115.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 6109-6115
-
-
Nakano, A.1
-
59
-
-
0035235736
-
Mitotic kinases as regulators of cell division and its checkpoints
-
Nigg E.A. Mitotic kinases as regulators of cell division and its checkpoints. Nat. Rev. Mol. Cell Biol. 2001, 2:21-32.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 21-32
-
-
Nigg, E.A.1
-
60
-
-
19344363250
-
Pathophysiological roles of G-protein-coupled receptor kinases
-
Metaye T., et al. Pathophysiological roles of G-protein-coupled receptor kinases. Cell. Signal. 2005, 17:917-928.
-
(2005)
Cell. Signal.
, vol.17
, pp. 917-928
-
-
Metaye, T.1
-
61
-
-
47849125977
-
Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas
-
Metaye T., et al. Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas. J. Endocrinol. 2008, 198:101-110.
-
(2008)
J. Endocrinol.
, vol.198
, pp. 101-110
-
-
Metaye, T.1
-
62
-
-
0033869812
-
Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors
-
Peppel K., et al. Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors. Circulation 2000, 102:793-799.
-
(2000)
Circulation
, vol.102
, pp. 793-799
-
-
Peppel, K.1
-
63
-
-
75749118972
-
G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression
-
Penela P., et al. G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:1118-1123.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 1118-1123
-
-
Penela, P.1
-
64
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
65
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson M.P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430:631-639.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
66
-
-
0034940160
-
Neurodegenerative tauopathies
-
Lee V.M., et al. Neurodegenerative tauopathies. Annu. Rev. Neurosci. 2001, 24:1121-1159.
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1121-1159
-
-
Lee, V.M.1
-
67
-
-
0345602771
-
Amyloid β protein toxicity mediated by the formation of amyloid-β protein precursor complexes
-
Lu D.C., et al. Amyloid β protein toxicity mediated by the formation of amyloid-β protein precursor complexes. Ann. Neurol. 2003, 54:781-789.
-
(2003)
Ann. Neurol.
, vol.54
, pp. 781-789
-
-
Lu, D.C.1
-
68
-
-
33645300736
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production
-
Pastorino L., et al. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production. Nature 2006, 440:528-534.
-
(2006)
Nature
, vol.440
, pp. 528-534
-
-
Pastorino, L.1
-
69
-
-
33646511135
-
Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis
-
Sultana R., et al. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: a redox proteomics analysis. Neurobiol. Aging 2006, 27:918-925.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 918-925
-
-
Sultana, R.1
-
70
-
-
43049143027
-
Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy
-
Lim J., et al. Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy. J. Clin. Invest. 2008, 118:1877-1889.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1877-1889
-
-
Lim, J.1
-
71
-
-
0036884733
-
Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein
-
Lotharius J., Brundin P. Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. Nat. Rev. Neurosci. 2002, 3:932-942.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 932-942
-
-
Lotharius, J.1
Brundin, P.2
-
72
-
-
33645238274
-
Prolyl-isomerase Pin1 accumulates in lewy bodies of parkinson disease and facilitates formation of α-synuclein inclusions
-
Ryo A. Prolyl-isomerase Pin1 accumulates in lewy bodies of parkinson disease and facilitates formation of α-synuclein inclusions. J. Biol. Chem. 2006, 281:4117-4125.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4117-4125
-
-
Ryo, A.1
-
73
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn E.H. Switching and signaling at the telomere. Cell 2001, 106:661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
74
-
-
34548667973
-
Telomere length, stem cells and aging
-
Blasco M.A. Telomere length, stem cells and aging. Nat. Chem. Biol. 2007, 3:640-649.
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 640-649
-
-
Blasco, M.A.1
-
75
-
-
0029586089
-
A human telomeric protein
-
Chong L., et al. A human telomeric protein. Science 1995, 270:1663-1667.
-
(1995)
Science
, vol.270
, pp. 1663-1667
-
-
Chong, L.1
-
76
-
-
0033961281
-
Control of human telomere length by TRF1 and TRF2
-
Smogorzewska A., et al. Control of human telomere length by TRF1 and TRF2. Mol. Cell. Biol. 2000, 20:1659-1668.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1659-1668
-
-
Smogorzewska, A.1
-
77
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
van Steensel B., de Lange T. Control of telomere length by the human telomeric protein TRF1. Nature 1997, 385:740-743.
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
van Steensel, B.1
de Lange, T.2
-
78
-
-
0031443638
-
Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis
-
Shen M., et al. Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:13618-13623.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13618-13623
-
-
Shen, M.1
-
79
-
-
58149351370
-
Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance
-
Lee T.H., et al. Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance. Nat. Cell Biol. 2009, 11:97-105.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 97-105
-
-
Lee, T.H.1
-
80
-
-
0037213048
-
Telomere shortening in T cells correlates with Alzheimer's disease status
-
Panossian L.A., et al. Telomere shortening in T cells correlates with Alzheimer's disease status. Neurobiol. Aging 2003, 24:77-84.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 77-84
-
-
Panossian, L.A.1
-
81
-
-
34547132819
-
The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage
-
De Nicola F., et al. The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage. J. Biol. Chem. 2007, 282:19685-19691.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 19685-19691
-
-
De Nicola, F.1
-
82
-
-
2942547565
-
Pin1 links the activities of c-Abl and p300 in regulating p73 function
-
Mantovani F., et al. Pin1 links the activities of c-Abl and p300 in regulating p73 function. Mol. Cell 2004, 14:625-636.
-
(2004)
Mol. Cell
, vol.14
, pp. 625-636
-
-
Mantovani, F.1
-
83
-
-
63149174264
-
Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-κB
-
Peloponese J.M., et al. Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-κB. J. Virol. 2009, 83:3238-3248.
-
(2009)
J. Virol.
, vol.83
, pp. 3238-3248
-
-
Peloponese, J.M.1
-
84
-
-
25844441096
-
Skp2 ubiquitin ligase
-
Skp2 ubiquitin ligase. Mol. Cell 2005, 20:9-19.
-
(2005)
Mol. Cell
, vol.20
, pp. 9-19
-
-
Hao, B.1
-
85
-
-
69949134410
-
Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process
-
Zhou W., et al. Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process. J. Biol. Chem. 2009, 284:23980-23988.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 23980-23988
-
-
Zhou, W.1
-
86
-
-
0026636883
-
The regulation of transcription by phosphorylation
-
Hunter T., Karin M. The regulation of transcription by phosphorylation. Cell 1992, 70:375-387.
-
(1992)
Cell
, vol.70
, pp. 375-387
-
-
Hunter, T.1
Karin, M.2
-
87
-
-
0035947078
-
Pin1 acts catalytically to promote a conformational change in Cdc25
-
Stukenberg P.T., Kirschner M.W. Pin1 acts catalytically to promote a conformational change in Cdc25. Mol. Cell 2001, 7:1071-1083.
-
(2001)
Mol. Cell
, vol.7
, pp. 1071-1083
-
-
Stukenberg, P.T.1
Kirschner, M.W.2
-
88
-
-
0029983519
-
Cellular signaling pathways and cytoskeletal organization
-
Kosik K.S., et al. Cellular signaling pathways and cytoskeletal organization. Ann. N. Y. Acad. Sci. 1996, 777:114-120.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.777
, pp. 114-120
-
-
Kosik, K.S.1
-
89
-
-
0003374626
-
Tau protein pathology in neurodegenerative diseases
-
Spillantini M.G., Goedert M. Tau protein pathology in neurodegenerative diseases. Trends Neurosci. 1998, 21:428-433.
-
(1998)
Trends Neurosci.
, vol.21
, pp. 428-433
-
-
Spillantini, M.G.1
Goedert, M.2
-
90
-
-
0344625369
-
Characterization of the phosphorylation sites of human high molecular weight neurofilament protein by electrospray ionization tandem mass spectrometry and database searching
-
Jaffe H., et al. Characterization of the phosphorylation sites of human high molecular weight neurofilament protein by electrospray ionization tandem mass spectrometry and database searching. Biochemistry 1998, 37:3931-3940.
-
(1998)
Biochemistry
, vol.37
, pp. 3931-3940
-
-
Jaffe, H.1
-
91
-
-
0029022205
-
Neuronal cyclin-dependent kinase-5 phosphorylation sites in neurofilament protein (NF-H) are dephosphorylated by protein phosphatase 2A
-
Veeranna K.T., et al. Neuronal cyclin-dependent kinase-5 phosphorylation sites in neurofilament protein (NF-H) are dephosphorylated by protein phosphatase 2A. J. Neurochem. 1995, 64:2681-2690.
-
(1995)
J. Neurochem.
, vol.64
, pp. 2681-2690
-
-
Veeranna, K.T.1
-
92
-
-
72449200109
-
Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins
-
Rudrabhatla P., et al. Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins. J. Neurosci. 2009, 29:14869-14880.
-
(2009)
J. Neurosci.
, vol.29
, pp. 14869-14880
-
-
Rudrabhatla, P.1
-
93
-
-
19944430124
-
Regulation of Raf-1 by direct feedback phosphorylation
-
Dougherty M.K., et al. Regulation of Raf-1 by direct feedback phosphorylation. Mol. Cell 2005, 17:215-224.
-
(2005)
Mol. Cell
, vol.17
, pp. 215-224
-
-
Dougherty, M.K.1
-
94
-
-
0344011538
-
Pin1 modulates the structure and function of human RNA polymerase II
-
Xu Y.X., et al. Pin1 modulates the structure and function of human RNA polymerase II. Genes Dev. 2003, 17:2765-2776.
-
(2003)
Genes Dev.
, vol.17
, pp. 2765-2776
-
-
Xu, Y.X.1
-
95
-
-
34247196176
-
The prolyl isomerase Pin1 functions in mitotic chromosome condensation
-
Xu Y.X., Manley J.L. The prolyl isomerase Pin1 functions in mitotic chromosome condensation. Mol. Cell 2007, 26:287-300.
-
(2007)
Mol. Cell
, vol.26
, pp. 287-300
-
-
Xu, Y.X.1
Manley, J.L.2
-
96
-
-
70350028604
-
A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity
-
Lu J., et al. A novel functional variant (-842G>C) in the PIN1 promoter contributes to decreased risk of squamous cell carcinoma of the head and neck by diminishing the promoter activity. Carcinogenesis 2009, 30:1717-1721.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1717-1721
-
-
Lu, J.1
-
97
-
-
33751327516
-
PIN1 promoter polymorphisms are associated with Alzheimer's disease
-
Segat L., et al. PIN1 promoter polymorphisms are associated with Alzheimer's disease. Neurobiol. Aging 2007, 28:69-74.
-
(2007)
Neurobiol. Aging
, vol.28
, pp. 69-74
-
-
Segat, L.1
-
98
-
-
80053292119
-
A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease
-
Ma S.L., et al. A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease. Neurobiol. Aging 2010, 10.1016/j.physletb.2003.10.071.
-
(2010)
Neurobiol. Aging
-
-
Ma, S.L.1
-
99
-
-
1842763560
-
Pinning down cell signaling, cancer and Alzheimer's disease
-
Lu K.P. Pinning down cell signaling, cancer and Alzheimer's disease. Trends Biochem. Sci. 2004, 29:200-209.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 200-209
-
-
Lu, K.P.1
-
100
-
-
27744536481
-
Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells
-
Eckerdt F. Polo-like kinase 1-mediated phosphorylation stabilizes Pin1 by inhibiting its ubiquitination in human cells. J. Biol. Chem. 2005, 280:36575-36583.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36575-36583
-
-
Eckerdt, F.1
-
101
-
-
33746359639
-
The death-associated protein kinases: structure, function, and beyond
-
Bialik S., Kimchi A. The death-associated protein kinases: structure, function, and beyond. Annu. Rev. Biochem. 2006, 75:189-210.
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 189-210
-
-
Bialik, S.1
Kimchi, A.2
-
102
-
-
0035141040
-
ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation
-
ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat. Cell Biol. 2001, 3:1-7.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 1-7
-
-
Raveh, T.1
-
103
-
-
77951184824
-
Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration
-
Pan C.Q., et al. Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration. J. Cell Sci. 2010, 123:903-916.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 903-916
-
-
Pan, C.Q.1
-
104
-
-
44449109478
-
Trophoblastic p53 is stabilised by a cis-trans isomerisation necessary for the formation of high molecular weight complexes involving the N-terminus of p53
-
Cohen M., et al. Trophoblastic p53 is stabilised by a cis-trans isomerisation necessary for the formation of high molecular weight complexes involving the N-terminus of p53. Biochimie 2008, 90:855-862.
-
(2008)
Biochimie
, vol.90
, pp. 855-862
-
-
Cohen, M.1
-
105
-
-
68249119759
-
Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation
-
Siepe D., Jentsch S. Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation. Nat. Cell Biol. 2009, 11:967-972.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 967-972
-
-
Siepe, D.1
Jentsch, S.2
-
106
-
-
34547700604
-
Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury
-
Li Q.M., et al. Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. J. Neurosci. 2007, 27:8395-8404.
-
(2007)
J. Neurosci.
, vol.27
, pp. 8395-8404
-
-
Li, Q.M.1
-
107
-
-
77955834772
-
Phosphorylation stabilizes Nanog by promoting its interaction with Pin1
-
Moretto-Zita M., et al. Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:13312-13317.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 13312-13317
-
-
Moretto-Zita, M.1
-
108
-
-
79953193459
-
A distinct role for Pin1 in the induction and maintenance of pluripotency
-
Nishi M., et al. A distinct role for Pin1 in the induction and maintenance of pluripotency. J. Biol. Chem. 2011, 286:11593-11603.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 11593-11603
-
-
Nishi, M.1
-
109
-
-
61849086777
-
The prolyl isomerase Pin1 stabilizes the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein and promotes malignant transformation
-
Jeong S.J., et al. The prolyl isomerase Pin1 stabilizes the human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein and promotes malignant transformation. Biochem. Biophys. Res. Commun. 2009, 381:294-299.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.381
, pp. 294-299
-
-
Jeong, S.J.1
-
110
-
-
77949264933
-
Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes
-
Manganaro L., et al. Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes. Nat. Med. 2010, 16:329-333.
-
(2010)
Nat. Med.
, vol.16
, pp. 329-333
-
-
Manganaro, L.1
-
111
-
-
33947303068
-
Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis
-
Pang R., et al. Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. Gastroenterology 2007, 132:1088-1103.
-
(2007)
Gastroenterology
, vol.132
, pp. 1088-1103
-
-
Pang, R.1
-
112
-
-
27444440554
-
Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1
-
Monje P., et al. Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1. J. Biol. Chem. 2005, 280:35081-35084.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35081-35084
-
-
Monje, P.1
-
113
-
-
22544461011
-
Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint
-
Campaner S., et al. Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint. Mol. Cell. Biol. 2005, 25:6660-6672.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6660-6672
-
-
Campaner, S.1
-
114
-
-
13444259420
-
The multifunctional nuclear protein p54nrb is multiphosphorylated in mitosis and interacts with the mitotic regulator Pin1
-
Proteau A., et al. The multifunctional nuclear protein p54nrb is multiphosphorylated in mitosis and interacts with the mitotic regulator Pin1. J. Mol. Biol. 2005, 346:1163-1172.
-
(2005)
J. Mol. Biol.
, vol.346
, pp. 1163-1172
-
-
Proteau, A.1
-
115
-
-
33750801024
-
The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes
-
Esnault S., et al. The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. J. Immunol. 2006, 177:6999-7006.
-
(2006)
J. Immunol.
, vol.177
, pp. 6999-7006
-
-
Esnault, S.1
-
116
-
-
5444234359
-
EL signaling pathway in neuronal apoptosis
-
EL signaling pathway in neuronal apoptosis. J. Neurosci. 2004, 24:8762-8770.
-
(2004)
J. Neurosci.
, vol.24
, pp. 8762-8770
-
-
Becker, E.B.1
-
117
-
-
41649088278
-
A topoisomerase II-dependent mechanism for resetting replicons at the S-M-phase transition
-
Cuvier O., et al. A topoisomerase II-dependent mechanism for resetting replicons at the S-M-phase transition. Genes Dev. 2008, 22:860-865.
-
(2008)
Genes Dev.
, vol.22
, pp. 860-865
-
-
Cuvier, O.1
-
118
-
-
0036097027
-
Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation
-
Basu A., et al. Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation. Neoplasia 2002, 4:218-227.
-
(2002)
Neoplasia
, vol.4
, pp. 218-227
-
-
Basu, A.1
-
119
-
-
0035524625
-
Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1
-
Pathan N., et al. Microtubule-targeting drugs induce bcl-2 phosphorylation and association with Pin1. Neoplasia 2001, 3:550-559.
-
(2001)
Neoplasia
, vol.3
, pp. 550-559
-
-
Pathan, N.1
-
120
-
-
61349151785
-
Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability
-
Lam P.B., et al. Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. Mol. Cancer 2008, 7:91.
-
(2008)
Mol. Cancer
, vol.7
, pp. 91
-
-
Lam, P.B.1
-
121
-
-
77449115522
-
Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor γ activity through the direct binding to the activation function-1 domain
-
Fujimoto Y., et al. Proline cis/trans-isomerase Pin1 regulates peroxisome proliferator-activated receptor γ activity through the direct binding to the activation function-1 domain. J. Biol. Chem. 2010, 285:3126-3132.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 3126-3132
-
-
Fujimoto, Y.1
-
122
-
-
69249087271
-
The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55
-
van der Horst A., Khanna K.K. The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55. Cancer Res. 2009, 69:6651-6659.
-
(2009)
Cancer Res.
, vol.69
, pp. 6651-6659
-
-
van der Horst, A.1
Khanna, K.K.2
-
123
-
-
67650092976
-
Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation
-
Liao Y., et al. Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation. Oncogene 2009, 28:2436-2445.
-
(2009)
Oncogene
, vol.28
, pp. 2436-2445
-
-
Liao, Y.1
-
124
-
-
74049131292
-
Pin1At encoding a peptidyl-prolyl cis/trans isomerase regulates flowering time in Arabidopsis
-
Wang Y., et al. Pin1At encoding a peptidyl-prolyl cis/trans isomerase regulates flowering time in Arabidopsis. Mol. Cell 2010, 37:112-122.
-
(2010)
Mol. Cell
, vol.37
, pp. 112-122
-
-
Wang, Y.1
-
125
-
-
33745830461
-
Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1
-
Yu L., et al. Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1. J. Biol. Chem. 2006, 281:18201-18207.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 18201-18207
-
-
Yu, L.1
-
126
-
-
33744499683
-
Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
-
Saitoh T., et al. Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1. Nat. Immunol. 2006, 7:598-605.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 598-605
-
-
Saitoh, T.1
-
127
-
-
53749085961
-
Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT
-
Stanya K.J., et al. Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT. J. Cell Biol. 2008, 183:49-61.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 49-61
-
-
Stanya, K.J.1
-
128
-
-
34547642807
-
Negative regulation of Pim-1 protein kinase levels by the B56β subunit of PP2A
-
Ma J., et al. Negative regulation of Pim-1 protein kinase levels by the B56β subunit of PP2A. Oncogene 2007, 26:5145-5153.
-
(2007)
Oncogene
, vol.26
, pp. 5145-5153
-
-
Ma, J.1
-
129
-
-
54749134224
-
kip1 expression through inhibition of Forkhead box O tumor suppressors
-
kip1 expression through inhibition of Forkhead box O tumor suppressors. Cancer Res. 2008, 68:7597-7605.
-
(2008)
Cancer Res.
, vol.68
, pp. 7597-7605
-
-
Brenkman, A.B.1
-
130
-
-
75149185157
-
Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin β-subunit gene transcription
-
Luo Z., et al. Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin β-subunit gene transcription. Mol. Cell. Biol. 2010, 30:745-763.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 745-763
-
-
Luo, Z.1
-
131
-
-
78650743362
-
Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A
-
Mitchell D.J., et al. Phosphorylation/dephosphorylation of human SULT4A1: role of Erk1 and PP2A. Biochim. Biophys. Acta 2011, 1813:231-237.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 231-237
-
-
Mitchell, D.J.1
-
132
-
-
67650824974
-
Cytosolic aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1
-
Mitchell D.J., Minchin R.F. Cytosolic aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1. Mol. Pharmacol. 2009, 76:388-395.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 388-395
-
-
Mitchell, D.J.1
Minchin, R.F.2
-
133
-
-
78049397634
-
Proline isomerase Pin1 represses terminal differentiation and myocyte enhancer factor 2C function in skeletal muscle cells
-
Magli A., et al. Proline isomerase Pin1 represses terminal differentiation and myocyte enhancer factor 2C function in skeletal muscle cells. J. Biol. Chem. 2010, 285:34518-34527.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34518-34527
-
-
Magli, A.1
-
134
-
-
37549031354
-
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx
-
Ryo A., et al. A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx. J. Biol. Chem. 2007, 282:36671-36681.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36671-36681
-
-
Ryo, A.1
-
135
-
-
33745095542
-
Pin1 allows for differential Tau dephosphorylation in neuronal cells
-
Hamdane M., et al. Pin1 allows for differential Tau dephosphorylation in neuronal cells. Mol. Cell. Neurosci. 2006, 32:155-160.
-
(2006)
Mol. Cell. Neurosci.
, vol.32
, pp. 155-160
-
-
Hamdane, M.1
-
136
-
-
37849032065
-
Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins
-
Li M., et al. Binding of phosphatase inhibitor-2 to prolyl isomerase Pin1 modifies specificity for mitotic phosphoproteins. Biochemistry 2008, 47:292-300.
-
(2008)
Biochemistry
, vol.47
, pp. 292-300
-
-
Li, M.1
-
137
-
-
38849085399
-
Pin1 regulates TGF-β1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis
-
Shen Z.J., et al. Pin1 regulates TGF-β1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J. Clin. Invest. 2008, 118:479-490.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 479-490
-
-
Shen, Z.J.1
-
138
-
-
70349673290
-
The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism
-
Nechama M., et al. The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism. J. Clin. Invest. 2009, 119:3102-3114.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 3102-3114
-
-
Nechama, M.1
-
139
-
-
20744432450
-
Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage
-
Berger M., et al. Mutations in proline 82 of p53 impair its activation by Pin1 and Chk2 in response to DNA damage. Mol. Cell. Biol. 2005, 25:5380-5388.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5380-5388
-
-
Berger, M.1
-
140
-
-
34249948703
-
Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1
-
Takahashi K., et al. Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1. Oncogene 2007, 26:3835-3845.
-
(2007)
Oncogene
, vol.26
, pp. 3835-3845
-
-
Takahashi, K.1
-
141
-
-
33846925252
-
Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression
-
Toledo F., et al. Mouse mutants reveal that putative protein interaction sites in the p53 proline-rich domain are dispensable for tumor suppression. Mol. Cell. Biol. 2007, 27:1425-1432.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 1425-1432
-
-
Toledo, F.1
-
142
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
-
143
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
144
-
-
0038143611
-
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
-
Chambers I., et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003, 113:643-655.
-
(2003)
Cell
, vol.113
, pp. 643-655
-
-
Chambers, I.1
|