-
1
-
-
0037012041
-
The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells
-
Baptiste, N., P. Friedlander, X. Chen, and C. Prives. 2002. The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. Oncogene 21:9-21.
-
(2002)
Oncogene
, vol.21
, pp. 9-21
-
-
Baptiste, N.1
Friedlander, P.2
Chen, X.3
Prives, C.4
-
2
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek, J., and J. Lukas. 2003. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3:421-429.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
3
-
-
0035830895
-
A role for the polyproline domain of p53 in its regulation by Mdm2
-
Berger, M., R. Vogt Sionov, A. J. Levine, and Y. Haupt. 2001. A role for the polyproline domain of p53 in its regulation by Mdm2. J. Biol. Chem. 276:3785-3790.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3785-3790
-
-
Berger, M.1
Vogt Sionov, R.2
Levine, A.J.3
Haupt, Y.4
-
5
-
-
0033598754
-
Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage
-
Chehab, N. H., A. Malikzay, E. S. Stavridi, and T. D. Halazonetis. 1999. Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage. Proc. Natl. Acad. Sci. USA 96:13777-13782.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13777-13782
-
-
Chehab, N.H.1
Malikzay, A.2
Stavridi, E.S.3
Halazonetis, T.D.4
-
6
-
-
0842278331
-
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
-
Chipuk, J. E., T. Kuwana, L. Bouchier-Hayes, N. M. Droin, D. D. Newmeyer, M. Schuler, and D. R. Green. 2004. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303:1010-1014.
-
(2004)
Science
, vol.303
, pp. 1010-1014
-
-
Chipuk, J.E.1
Kuwana, T.2
Bouchier-Hayes, L.3
Droin, N.M.4
Newmeyer, D.D.5
Schuler, M.6
Green, D.R.7
-
7
-
-
0042854721
-
Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain
-
Craig, A., M. Scott, L. Burch, G. Smith, K. Ball, and T. Hupp. 2003. Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain. EMBO Rep. 4:787-792.
-
(2003)
EMBO Rep.
, vol.4
, pp. 787-792
-
-
Craig, A.1
Scott, M.2
Burch, L.3
Smith, G.4
Ball, K.5
Hupp, T.6
-
8
-
-
0032473350
-
The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1
-
Crenshaw, D. G., J. Yang, A. R. Means, and S. Kornbluth. 1998. The mitotic peptidyl-prolyl isomerase, Pin1, interacts with Cdc25 and Plx1. EMBO J. 17:1315-1327.
-
(1998)
EMBO J.
, vol.17
, pp. 1315-1327
-
-
Crenshaw, D.G.1
Yang, J.2
Means, A.R.3
Kornbluth, S.4
-
9
-
-
0043170851
-
The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions
-
Edwards, S. J., L. Hananeia, M. R. Eccles, Y. F. Zhang, and A. W. Braithwaite. 2003. The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions. Oncogene 22:4517-4523.
-
(2003)
Oncogene
, vol.22
, pp. 4517-4523
-
-
Edwards, S.J.1
Hananeia, L.2
Eccles, M.R.3
Zhang, Y.F.4
Braithwaite, A.W.5
-
10
-
-
0035817764
-
Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway
-
Falck, J., C. Lukas, M. Protopopova, J. Lukas, G. Selivanova, and J. Bartek. 2001. Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway. Oncogene 20:5503-5510.
-
(2001)
Oncogene
, vol.20
, pp. 5503-5510
-
-
Falck, J.1
Lukas, C.2
Protopopova, M.3
Lukas, J.4
Selivanova, G.5
Bartek, J.6
-
11
-
-
0029985647
-
Cell type-specific inhibition of p53-mediated apoptosis by mdm2
-
Haupt, Y., Y. Barak, and M. Oren. 1996. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 15:1596-1606.
-
(1996)
EMBO J.
, vol.15
, pp. 1596-1606
-
-
Haupt, Y.1
Barak, Y.2
Oren, M.3
-
12
-
-
0036491204
-
p53: An internal investigation
-
Hayon, I. L., and Y. Haupt. 2002. p53: an internal investigation. Cell Cycle 1:111-116.
-
(2002)
Cell Cycle
, vol.1
, pp. 111-116
-
-
Hayon, I.L.1
Haupt, Y.2
-
13
-
-
0034629072
-
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
-
Hirao, A., Y. Y. Kong, S. Matsuoka, A. Wakeham, J. Ruland, H. Yoshida, D. Liu, S. J. Elledge, and T. W. Mak. 2000. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287:1824-1827.
-
(2000)
Science
, vol.287
, pp. 1824-1827
-
-
Hirao, A.1
Kong, Y.Y.2
Matsuoka, S.3
Wakeham, A.4
Ruland, J.5
Yoshida, H.6
Liu, D.7
Elledge, S.J.8
Mak, T.W.9
-
15
-
-
0642347849
-
The peptidyl-prolyl isomerase Pin1
-
Joseph, J. D., E. S. Yeh, K. I. Swenson, A. R. Means, and Winkler. 2003. The peptidyl-prolyl isomerase Pin1. Prog. Cell Cycle Res. 5:477-487.
-
(2003)
Prog. Cell Cycle Res.
, vol.5
, pp. 477-487
-
-
Joseph, J.D.1
Yeh, E.S.2
Swenson, K.I.3
Means, A.R.4
Winkler5
-
16
-
-
0141457429
-
Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics
-
Lu, K. P. 2003. Prolyl isomerase Pin1 as a molecular target for cancer diagnostics and therapeutics. Cancer Cell 4:175-180.
-
(2003)
Cancer Cell
, vol.4
, pp. 175-180
-
-
Lu, K.P.1
-
17
-
-
0034840950
-
Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
-
Ryo, A., M. Nakamura, G. Wulf, Y. C. Liou, and K. P. Lu. 2001. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat. Cell Biol. 3:793-801.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 793-801
-
-
Ryo, A.1
Nakamura, M.2
Wulf, G.3
Liou, Y.C.4
Lu, K.P.5
-
18
-
-
0030798557
-
The polyproline region of p53 is required to activate apoptosis but not growth arrest
-
Sakamuro, D., P. Sabbatini, E. White, and G. C. Prendergast. 1997. The polyproline region of p53 is required to activate apoptosis but not growth arrest. Oncogene 15:887-898.
-
(1997)
Oncogene
, vol.15
, pp. 887-898
-
-
Sakamuro, D.1
Sabbatini, P.2
White, E.3
Prendergast, G.C.4
-
19
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh, S. Y., J. Ahn, K. Tamai, Y. Taya, and C. Prives. 2000. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14:289-300.
-
(2000)
Genes Dev.
, vol.14
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
20
-
-
0033230581
-
The cellular response to p53: The decision between life and death
-
Sionov, R. V., and Y. Haupt. 1999. The cellular response to p53: the decision between life and death. Oncogene 18:6145-6157.
-
(1999)
Oncogene
, vol.18
, pp. 6145-6157
-
-
Sionov, R.V.1
Haupt, Y.2
-
21
-
-
0035947078
-
Pin1 acts catalytically to promote a conformational change in Cdc25
-
Stukenberg, P. T., and M. W. Kirschner. 2001. Pin1 acts catalytically to promote a conformational change in Cdc25. Mol. Cell 7:1071-1083.
-
(2001)
Mol. Cell
, vol.7
, pp. 1071-1083
-
-
Stukenberg, P.T.1
Kirschner, M.W.2
-
22
-
-
0029787301
-
A novel p53 germline alteration identified in a late onset breast cancer kindred
-
Sun, X. F., O. Johannsson, S. Hakansson, G. Sellberg, B. Nordenskjold, H. Olsson, and A. Borg. 1996. A novel p53 germline alteration identified in a late onset breast cancer kindred. Oncogene 13:407-411.
-
(1996)
Oncogene
, vol.13
, pp. 407-411
-
-
Sun, X.F.1
Johannsson, O.2
Hakansson, S.3
Sellberg, G.4
Nordenskjold, B.5
Olsson, H.6
Borg, A.7
-
23
-
-
0030046638
-
p53 mutations in bladder tumors from arylamine-exposed workers
-
Taylor, J. A., Y. Li, M. He, T. Mason, C. Mettlin, W. J. Vogler, S. Maygarden, and E. Liu. 1996. p53 mutations in bladder tumors from arylamine-exposed workers. Cancer Res. 56:294-298.
-
(1996)
Cancer Res.
, vol.56
, pp. 294-298
-
-
Taylor, J.A.1
Li, Y.2
He, M.3
Mason, T.4
Mettlin, C.5
Vogler, W.J.6
Maygarden, S.7
Liu, E.8
-
24
-
-
0033119627
-
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2
-
Unger, T., T. Juven-Gershon, E. Moallem, M. Berger, R. Vogt Sionov, G. Lozano, M. Oren, and Y. Haupt. 1999. Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2. EMBO J. 18:1805-1814.
-
(1999)
EMBO J.
, vol.18
, pp. 1805-1814
-
-
Unger, T.1
Juven-Gershon, T.2
Moallem, E.3
Berger, M.4
Vogt Sionov, R.5
Lozano, G.6
Oren, M.7
Haupt, Y.8
-
25
-
-
0032541325
-
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
-
Venot, C., M. Maratrat, C. Dureuil, E. Conseiller, L. Bracco, and L. Debussche. 1998. The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J. 17:4668-4679.
-
(1998)
EMBO J.
, vol.17
, pp. 4668-4679
-
-
Venot, C.1
Maratrat, M.2
Dureuil, C.3
Conseiller, E.4
Bracco, L.5
Debussche, L.6
-
26
-
-
0005815475
-
The regulation of p53 growth suppression
-
M. V. Blagosklonny (ed.). Landes Bioscience, Georgetown, Tex.
-
Vogt Sionov, R., L. I. Hayon, and Y. Haupt. 2001. The regulation of p53 growth suppression, p. 106-125. In M. V. Blagosklonny (ed.), Cell cycle checkpoints and cancer. Landes Bioscience, Georgetown, Tex.
-
(2001)
Cell Cycle Checkpoints and Cancer
, pp. 106-125
-
-
Vogt Sionov, R.1
Hayon, L.I.2
Haupt, Y.3
-
27
-
-
0030448650
-
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
-
Walker, K. K., and A. J. Levine. 1996. Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proc. Natl. Acad. Sci. USA 93:15335-15340.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 15335-15340
-
-
Walker, K.K.1
Levine, A.J.2
-
28
-
-
0037073713
-
Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage
-
Wulf, G. M., Y. C. Liou, A. Ryo, S. W. Lee, and K. P. Lu. 2002. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J. Biol. Chem. 277:47976-47979.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47976-47979
-
-
Wulf, G.M.1
Liou, Y.C.2
Ryo, A.3
Lee, S.W.4
Lu, K.P.5
-
29
-
-
18644384283
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
-
Zacchi, P., M. Gostissa, T. Uchida, C. Salvagno, F. Avolio, S. Volinia, Z. Ronai, G. Blandino, C. Schneider, and G. Del Sal. 2002. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature 419:853-857.
-
(2002)
Nature
, vol.419
, pp. 853-857
-
-
Zacchi, P.1
Gostissa, M.2
Uchida, T.3
Salvagno, C.4
Avolio, F.5
Volinia, S.6
Ronai, Z.7
Blandino, G.8
Schneider, C.9
Del Sal, G.10
-
30
-
-
18644384688
-
The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response
-
Zheng, H., H. You, X. Z. Zhou, S. A. Murray, T. Uchida, G. Wulf, L. Gu, X. Tang, K. P. Lu, and Z. X. Xiao. 2002. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature 419:849-853.
-
(2002)
Nature
, vol.419
, pp. 849-853
-
-
Zheng, H.1
You, H.2
Zhou, X.Z.3
Murray, S.A.4
Uchida, T.5
Wulf, G.6
Gu, L.7
Tang, X.8
Lu, K.P.9
Xiao, Z.X.10
-
31
-
-
0033602361
-
Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity
-
Zhu, J., J. Jiang, W. Zhou, K. Zhu, and X. Chen. 1999. Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity. Oncogene 18:2149-2155.
-
(1999)
Oncogene
, vol.18
, pp. 2149-2155
-
-
Zhu, J.1
Jiang, J.2
Zhou, W.3
Zhu, K.4
Chen, X.5
|