Pin1 links the activities of c-Abl and p300 in regulating p73 function

Molecular Cell

Volumn 14, Issue 5, 2004, Pages 625-636

  Mantovani, Fiamma ^a,b   Piazza, Silvano ^a   Gostissa, Monica ^a   Strano, Sabrina ^c   Zacchi, Paola ^a,e   Mantovani, Roberto ^d   Blandino, Giovanni ^c   Del Sal, Giannino ^a,b  

^a Laboratorio Nazionale CIB   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e SISSA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABELSON KINASE; ANTIINFECTIVE AGENT; ISOENZYME; ISOMERASE; PEPTIDYLPROLYL ISOMERASE PIN1; PROLINE DERIVATIVE; PROTEIN; PROTEIN P300; PROTEIN P73; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CATALYSIS; CONFORMATION; CONTROLLED STUDY; EMBRYO; GENOTOXICITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; STRESS; TRANSCRIPTION INITIATION;

ACETYLTRANSFERASES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; GENES, REGULATOR; GENES, TUMOR SUPPRESSOR; HISTONE ACETYLTRANSFERASES; HUMANS; MICE; NUCLEAR PROTEINS; PEPTIDYLPROLYL ISOMERASE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-ABL; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 2942547565     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2004.05.007     Document Type: Article

References (35)

1. Agami R., Blandino G., Oren M., Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature. 399:1999;809-813
2. Bergamaschi D., Gasco M., Hiller L., Sullivan A., Syed N., Trigiante G., Yulug I., Merlano M., Numico G., Comino A., et al. p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis. Cancer Cell. 3:2003;387-402
3. Bergamaschi D., Samuels Y., Jin B., Duraisingham S., Crook T., Lu X. ASPP1 and ASPP2. common activators of p53 family members Mol. Cell. Biol. 24:2004;1341-1350
4. Costanzo A., Merlo P., Pediconi N., Fulco M., Sartorelli V., Cole P.A., Fontemaggi G., Fanciulli M., Schiltz L., Blandino G., et al. DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. Mol. Cell. 9:2002;175-186
5. Flores E.R., Tsai K.Y., Crowley D., Sengupta S., Yang A., McKeon F., Jacks T. p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature. 416:2002;560-564
6. Fontemaggi G., Kela I., Amariglio N., Rechavi G., Krishnamurthy J., Strano S., Sacchi A., Givol D., Blandino G. Identification of direct p73 target genes combining DNA microarray and chromatin immunoprecipitation analyses. J. Biol. Chem. 277:2002;43359-43368
7. Fujimori F., Takahashi K., Uchida C., Uchida T. Mice lacking Pin1 develop normally, but are defective in entering cell cycle from G(0) arrest. Biochem. Biophys. Res. Commun. 265:1999;658-663
8. Fulco M., Costanzo A., Merlo P., Mangiacasale R., Strano S., Blandino G., Balsano C., Lavia P., Levrero M. p73 is regulated by phosphorylation at the G2/M transition. J. Biol. Chem. 278:2003;49196-49202
9. Gaiddon C., Lokshin M., Gross I., Levasseur D., Taya Y., Loeffler J.P., Prives C. Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73. J. Biol. Chem. 278:2003;27421-27431
10. Gong J.G., Costanzo A., Yang H.Q., Melino G., Kaelin W.G. Jr., Levrero M., Wang J.Y. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature. 399:1999;806-809
11. Irwin M.S., Kaelin W.G. p53 family update. p73 and p63 develop their own identities Cell Growth Differ. 12:2001;337-349
12. Irwin M.S., Kondo K., Marin M.C., Cheng L.S., Hahn W.C., Kaelin W.G. Chemosensitivity linked to p73 function. Cancer Cell. 3:2003;403-410
13. Jost C.A., Marin M.C., Kaelin W.G. Jr. p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature. 389:1997;191-194
14. Lee C.W., La Thangue N.B. Promoter specificity and stability control of the p53-related protein p73. Oncogene. 18:1999;4171-4181
15. Levrero M., De Laurenzi V., Costanzo A., Gong J., Melino G., Wang J.Y. Structure, function and regulation of p63 and p73. Cell Death Differ. 6:1999;1146-1153
16. Lohrum M.A., Vousden K.H. Regulation and activation of p53 and its family members. Cell Death Differ. 6:1999;1162-1168
17. Lowe S.W., Ruley H.E., Jacks T., Housman D.E. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell. 74:1993;957-967
18. Lu K.P., Hanes S.D., Hunter T. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature. 380:1996;544-547
19. Melino G., Bernassola F., Ranalli M., Yee K., Xing Zong W., Corazzari M., Knight A., Green D., Thompson C., Vousden K. p73 induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J. Biol. Chem. 279:1994;8076-8083
20. Minty A., Dumont X., Kaghad M., Caput D. Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif. J. Biol. Chem. 275:2000;36316-36323
21. Muller H., Bracken A.P., Vernell R., Moroni M.C., Christians F., Grassilli E., Prosperini E., Vigo E., Oliner J.D., Helin K. E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev. 15:2001;267-285
22. Pathan N., Aime-Sempe C., Kitada S., Haldar S., Reed J.C. Microtubule targeting drugs induce Bcl-2 phosphorylation and assaciation with Pin1. Neoplasia. 3:2001;70-79
23. Ryo A., Nakamura M., Wulf G., Liou Y.C., Lu K.P. Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC. Nat. Cell Biol. 3:2001;793-801
24. Salsi V., Caretti G., Wasner M., Reinhard W., Haugwitz U., Engeland K., Mantovani R. Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function. J. Biol. Chem. 278:2003;6642-6650
25. Sanchez-Prieto R., Sanchez-Arevalo V.J., Servitja J.M., Gutkind J.S. Regulation of p73 by c-Abl through the p38 MAP kinase pathway. Oncogene. 21:2002;974-979
26. Stukenberg P.T., Kirschner M.W. Pin1 acts catalytically to promote a conformational change in Cdc25. Mol. Cell. 7:2001;1071-1083
27. Tsai K.K., Yuan Z.M. c-Abl stabilizes p73 by a phosphorylation-augmented interaction. Cancer Res. 63:2003;3418-3424
28. Winkler K.E., Swenson K.I., Kornbluth S., Means A.R. Requirement of the prolyl isomerase Pin1 for the replication checkpoint. Science. 287:2000;1644-1647
29. Wulf G.M., Ryo A., Wulf G.G., Lee S.W., Niu T., Pektova V., Lu K.P. Pin1 is overexpressed in breast cancer and cooperates with Ras signalling in increasing the transcriptional activity of c-jun towards cyclin D1. EMBO J. 20:2001;3459-3472
30. Wulf G.M., Liou Y.C., Ryo A., Lee S.W., Lu K.P. Role of Pin1 in the regulation of p53 stability and p21 transactivation, and cell cycle checkpoints in response to DNA damage. J. Biol. Chem. 277:2002;47976-47979
31. Yuan Z.M., Shioya H., Ishiko T., Sun X., Gu J., Huang Y.Y., Lu H., Kharbanda S., Weichselbaum R., Kufe D. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature. 399:1999;814-817
32. Zacchi P., Gostissa M., Uchida T., Salvagno C., Avolio F., Volinia S., Ronai Z., Blandino G., Schneider C., Del Sal G. The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults. Nature. 419:2002;853-857
33. Zaika A.I., Kovalev S., Marchenko N.D., Moll U.M. Overexpression of the wild type p73 gene in breast cancer tissues and cell lines. Cancer Res. 59:1999;3257-3263
34. Zaika A., Irwin M., Sansome C., Moll U.M. Oncogenes induce and activate endogenous p73 protein. J. Biol. Chem. 276:2001;11310-11316
35. Zheng H., You H., Zhou X.Z., Murray S.A., Uchida T., Wulf G., Gu L., Tang X., Lu K.P., Xiao Z.X. The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response. Nature. 419:2002;849-853