Allostery in pharmacology: Thermodynamics, evolution and design

Progress in Biophysics and Molecular Biology

Volumn 106, Issue 3, 2011, Pages 463-473

  Maksay, Gábor ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

Conformational fluctuations; Homo hetero tropic cooperativity; Ligand gated ion channels; Receptor activation; Statistical energetic coupling; Thermodynamic discrimination of efficacy

Indexed keywords

LIGAND GATED ION CHANNEL;

ALLOSTERISM; ANIMAL; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR EVOLUTION; PHARMACOLOGY; PROTEIN SUBUNIT; REVIEW; SIGNAL TRANSDUCTION; THERMODYNAMICS;

ALLOSTERIC REGULATION; ANIMALS; EVOLUTION, MOLECULAR; HUMANS; LIGAND-GATED ION CHANNELS; PHARMACOLOGY; PROTEIN SUBUNITS; SIGNAL TRANSDUCTION; THERMODYNAMICS;

BACTERIA (MICROORGANISMS);

EID: 80053129150     PISSN: 00796107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbiomolbio.2011.01.001     Document Type: Review

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