Possible new targets for GPCR modulation: Allosteric interactions, plasma membrane domains, intercellular transfer and epigenetic mechanisms

Journal of Receptors and Signal Transduction

Volumn 31, Issue 5, 2011, Pages 315-331

  Agnati, Luigi Francesco ^a   Guidolin, Diego ^b   Leo, Giuseppina ^c   Guescini, Michele ^d   Pizzi, Marina ^a,e   Stocchi, Vilberto ^d   Spano, Pier Francesco ^a,e   Ghidoni, Roberta ^f   Ciruela, Francisco ^g   Genedani, Susanna ^c   Fuxe, Kjell ^h  

^a IRCCS SAN CAMILLO HOSPITAL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d UNIVERSITY OF URBINO   (Italy)

^e UNIVERSITY OF BRESCIA   (Italy)

^f IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^g UNIVERSITY OF BARCELONA   (Spain)

^h KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Epigenesis; Exosome; Homo and hetero oligomerization; Lipid rafts; Receptor mosaics; Roamer type of volume transmission; Tetraspanins

Indexed keywords

G PROTEIN COUPLED RECEPTOR; RESVERATROL; TETRASPANIN; TRANSCRIPTION FACTOR RELA;

ALLOSTERISM; BRAIN ISCHEMIA; CELL MEMBRANE; DRUG TARGETING; EPIGENETICS; EXOSOME; HUMAN; LIPID RAFT; MATHEMATICAL MODEL; NERVE CELL PLASTICITY; NEUROPHARMACOLOGY; NONHUMAN; OLIGOMERIZATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; RECEPTOR INTRINSIC ACTIVITY; REVIEW;

ALLOSTERIC REGULATION; CELL MEMBRANE; DRUG DESIGN; EPIGENESIS, GENETIC; HUMANS; MEMBRANE MICRODOMAINS; RECEPTORS, G-PROTEIN-COUPLED; TETRASPANINS;

EID: 80053016211     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2011.599393     Document Type: Review

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