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Volumn 10, Issue SUPPL. 1, 2010, Pages

Plasma membrane microdomains in aging and disease

Author keywords

Cholesterol; Lipid raft; Microdomain; Signal transduction

Indexed keywords

ABC TRANSPORTER A1; AEROLYSIN; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; BETA CYCLODEXTRIN; BETA SECRETASE; CAVEOLIN 1; CAVEOLIN 2; CAVEOLIN 3; CD36 ANTIGEN; CHOLERA TOXIN; CHOLESTEROL; CYTOLYSIN; FATTY ACID; GAMMA SECRETASE; GANGLIOSIDE; GANGLIOSIDE GM1; GANGLIOSIDE GM3; GLUCOSE TRANSPORTER 4; GLYCOSYLPHOSPHATIDYLINOSITOL; INSULIN RECEPTOR; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEMBRANE PROTEIN; SHIGA TOXIN; SPHINGOLIPID; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

EID: 77954672564     PISSN: 14441586     EISSN: 14470594     Source Type: Journal    
DOI: 10.1111/j.1447-0594.2010.00600.x     Document Type: Review
Times cited : (59)

References (101)
  • 1
    • 0030949124 scopus 로고    scopus 로고
    • Functional rafts in cell membranes
    • Simons K, Ikonen E. Functional rafts in cell membranes. Nature 1997, 387:569-572.
    • (1997) Nature , vol.387 , pp. 569-572
    • Simons, K.1    Ikonen, E.2
  • 2
    • 0034304851 scopus 로고    scopus 로고
    • Lipid rafts and signal transduction
    • Simons K, Toomre D. Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 2000, 1:31-39.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 31-39
    • Simons, K.1    Toomre, D.2
  • 3
    • 33746085241 scopus 로고    scopus 로고
    • Rafts defined
    • Pike LJ. Rafts defined. J Lipid Res 2006, 47:1597-1598.
    • (2006) J Lipid Res , vol.47 , pp. 1597-1598
    • Pike, L.J.1
  • 4
    • 0031558768 scopus 로고    scopus 로고
    • Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes?
    • Brown DA, London E. Structure of detergent-resistant membrane domains: does phase separation occur in biological membranes? Biochem Biophys Res Commun 1997, 240:1-7.
    • (1997) Biochem Biophys Res Commun , vol.240 , pp. 1-7
    • Brown, D.A.1    London, E.2
  • 5
    • 1642354334 scopus 로고    scopus 로고
    • Lipid rafts: heterogeneity on the high seas
    • Pike LJ. Lipid rafts: heterogeneity on the high seas. Biochem J 2004, 378:281-292.
    • (2004) Biochem J , vol.378 , pp. 281-292
    • Pike, L.J.1
  • 6
    • 1842536499 scopus 로고    scopus 로고
    • Rafts: scale-dependent, active lipid organization at the cell surface
    • Mayor S, Rao M. Rafts: scale-dependent, active lipid organization at the cell surface. Traffic 2004, 5:231-240.
    • (2004) Traffic , vol.5 , pp. 231-240
    • Mayor, S.1    Rao, M.2
  • 8
    • 0036860195 scopus 로고    scopus 로고
    • Age-dependent agonist-specific dysregulation of membrane-mediated signal transduction: emergence of the gate theory of aging
    • Yeo EJ, Park SC. Age-dependent agonist-specific dysregulation of membrane-mediated signal transduction: emergence of the gate theory of aging. Mech Ageing Dev 2002, 123:1563-1578.
    • (2002) Mech Ageing Dev , vol.123 , pp. 1563-1578
    • Yeo, E.J.1    Park, S.C.2
  • 9
    • 0034254660 scopus 로고    scopus 로고
    • Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction
    • Tamir A, Eisenbraun MD, Garcia GG, Miller RA. Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction. J Immunol 2000, 165:1243-1251.
    • (2000) J Immunol , vol.165 , pp. 1243-1251
    • Tamir, A.1    Eisenbraun, M.D.2    Garcia, G.G.3    Miller, R.A.4
  • 10
    • 0842309906 scopus 로고    scopus 로고
    • Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes
    • Larbi A, Douziech N, Dupuis G. Age-associated alterations in the recruitment of signal-transduction proteins to lipid rafts in human T lymphocytes. J Leukoc Biol 2004, 75:373-381.
    • (2004) J Leukoc Biol , vol.75 , pp. 373-381
    • Larbi, A.1    Douziech, N.2    Dupuis, G.3
  • 11
    • 0034617210 scopus 로고    scopus 로고
    • Up-regulation of caveolin attenuates epidermal growth factor signalling in senescent cells
    • Park WY, Park JS, Cho KA. Up-regulation of caveolin attenuates epidermal growth factor signalling in senescent cells. J Biol Chem 2000, 275:20847-20852.
    • (2000) J Biol Chem , vol.275 , pp. 20847-20852
    • Park, W.Y.1    Park, J.S.2    Cho, K.A.3
  • 12
    • 0036323674 scopus 로고    scopus 로고
    • Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
    • Volonte D, Zhang K, Lisanti MP, Galbiati F. Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts. Mol Biol Cell 2002, 13:2502-2517.
    • (2002) Mol Biol Cell , vol.13 , pp. 2502-2517
    • Volonte, D.1    Zhang, K.2    Lisanti, M.P.3    Galbiati, F.4
  • 13
    • 0036733578 scopus 로고    scopus 로고
    • Cholesterol, lipid rafts, and disease
    • Simons K, Ehehalt R. Cholesterol, lipid rafts, and disease. J Clin Invest 2002, 110:597-603.
    • (2002) J Clin Invest , vol.110 , pp. 597-603
    • Simons, K.1    Ehehalt, R.2
  • 14
    • 0035826795 scopus 로고    scopus 로고
    • A fluid connection: cholesterol and Aβ
    • Wolozin B. A fluid connection: cholesterol and Aβ. Proc Natl Acad Sci USA 2001, 98:5371-5373.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5371-5373
    • Wolozin, B.1
  • 15
    • 1842432088 scopus 로고    scopus 로고
    • Molecular dynamics and interactions for creation of stimulation-induced stabilized rafts from small unstable steady-state rafts
    • Kusumi A, Koyama-Honda I, Suzuki K. Molecular dynamics and interactions for creation of stimulation-induced stabilized rafts from small unstable steady-state rafts. Traffic 2004, 5:213-230.
    • (2004) Traffic , vol.5 , pp. 213-230
    • Kusumi, A.1    Koyama-Honda, I.2    Suzuki, K.3
  • 16
    • 33750714787 scopus 로고    scopus 로고
    • Detection of cholesterol-rich microdomains in the inner leaflet of the plasma membrane
    • Hayashi M, Shimada Y, Inomata M, Ohno-Iwashita Y. Detection of cholesterol-rich microdomains in the inner leaflet of the plasma membrane. Biochem Biophys Res Commun 2006, 351:713-718.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 713-718
    • Hayashi, M.1    Shimada, Y.2    Inomata, M.3    Ohno-Iwashita, Y.4
  • 17
    • 0034707082 scopus 로고    scopus 로고
    • Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts)
    • London E, Brown DA. Insolubility of lipids in triton X-100: physical origin and relationship to sphingolipid/cholesterol membrane domains (rafts). Biochim Biophys Acta 2000, 1508:182-195.
    • (2000) Biochim Biophys Acta , vol.1508 , pp. 182-195
    • London, E.1    Brown, D.A.2
  • 18
    • 0026512314 scopus 로고
    • Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
    • Brown DA, Rose JK. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell 1992, 68:533-544.
    • (1992) Cell , vol.68 , pp. 533-544
    • Brown, D.A.1    Rose, J.K.2
  • 19
    • 0036178403 scopus 로고    scopus 로고
    • Lipid rafts and little caves. Compartmentalized signaling in membrane microdomains
    • Zajchowski LD, Robbins SM. Lipid rafts and little caves. Compartmentalized signaling in membrane microdomains. Eur J Biochem 2002, 269:737-752.
    • (2002) Eur J Biochem , vol.269 , pp. 737-752
    • Zajchowski, L.D.1    Robbins, S.M.2
  • 20
    • 17244380947 scopus 로고    scopus 로고
    • Lipid rafts and membrane dynamics
    • Rajendran L, Simons K. Lipid rafts and membrane dynamics. J Cell Sci 2005, 118:1099-1102.
    • (2005) J Cell Sci , vol.118 , pp. 1099-1102
    • Rajendran, L.1    Simons, K.2
  • 21
    • 1942501973 scopus 로고    scopus 로고
    • Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains
    • Heijnen HFG, Van Lier M, Waaijenborg S. Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains. J Thromb Haemost 2003, 1:1161-1173.
    • (2003) J Thromb Haemost , vol.1 , pp. 1161-1173
    • Heijnen, H.F.G.1    Van Lier, M.2    Waaijenborg, S.3
  • 22
    • 0035859925 scopus 로고    scopus 로고
    • Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization
    • Gomez-Mouton C, Abad JL, Mira E. Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization. Proc Natl Acad Sci USA 2001, 98:9642-9647.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9642-9647
    • Gomez-Mouton, C.1    Abad, J.L.2    Mira, E.3
  • 23
    • 27644508227 scopus 로고    scopus 로고
    • Separation of a cholesterol-enriched microdomain involved in T-cell signal transduction
    • Shimada Y, Inomata M, Suzuki H, Hayashi M, Waheed AA, Ohno-Iwashita Y. Separation of a cholesterol-enriched microdomain involved in T-cell signal transduction. FEBS J 2005, 272:5454-5463.
    • (2005) FEBS J , vol.272 , pp. 5454-5463
    • Shimada, Y.1    Inomata, M.2    Suzuki, H.3    Hayashi, M.4    Waheed, A.A.5    Ohno-Iwashita, Y.6
  • 24
  • 25
    • 0029086362 scopus 로고
    • De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin
    • Fra AM, Williamson E, Simons K, Parton RG. De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc Natl Acad Sci USA 1995, 92:8655-8659.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8655-8659
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 26
    • 0028057494 scopus 로고
    • Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae
    • Parton RG. Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae. J Histochem Cytochem 1994, 42:155-166.
    • (1994) J Histochem Cytochem , vol.42 , pp. 155-166
    • Parton, R.G.1
  • 28
    • 0032570597 scopus 로고    scopus 로고
    • Lysenin, a novel sphingomyelin-specific binding protein
    • Yamaji A, Sekizawa Y, Emoto K. Lysenin, a novel sphingomyelin-specific binding protein. J Biol Chem 1998, 273:5300-5306.
    • (1998) J Biol Chem , vol.273 , pp. 5300-5306
    • Yamaji, A.1    Sekizawa, Y.2    Emoto, K.3
  • 29
    • 0021459790 scopus 로고
    • The use and abuse of filipin to localize cholesterol in membranes
    • Miller RG. The use and abuse of filipin to localize cholesterol in membranes. Cell Biol Int Rep 1984, 8:519-535.
    • (1984) Cell Biol Int Rep , vol.8 , pp. 519-535
    • Miller, R.G.1
  • 30
    • 1942454206 scopus 로고    scopus 로고
    • Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid rafts
    • Ohno-Iwashita Y, Shimada Y, Waheed AA. Perfringolysin O, a cholesterol-binding cytolysin, as a probe for lipid rafts. Anaerobe 2004, 10:125-134.
    • (2004) Anaerobe , vol.10 , pp. 125-134
    • Ohno-Iwashita, Y.1    Shimada, Y.2    Waheed, A.A.3
  • 31
    • 0023783454 scopus 로고
    • Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes
    • Ohno-Iwashita Y, Iwamoto M, Mitsui K, Ando S, Nagai Y. Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes. Eur J Biochem 1988, 176:95-101.
    • (1988) Eur J Biochem , vol.176 , pp. 95-101
    • Ohno-Iwashita, Y.1    Iwamoto, M.2    Mitsui, K.3    Ando, S.4    Nagai, Y.5
  • 32
    • 0030746612 scopus 로고    scopus 로고
    • A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol
    • Iwamoto M, Morita I, Fukuda M, Murota S, Ando S, Ohno-Iwashita Y. A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol. Biochim Biophys Acta 1997, 1327:222-230.
    • (1997) Biochim Biophys Acta , vol.1327 , pp. 222-230
    • Iwamoto, M.1    Morita, I.2    Fukuda, M.3    Murota, S.4    Ando, S.5    Ohno-Iwashita, Y.6
  • 33
    • 18744391355 scopus 로고    scopus 로고
    • The C-terminal domain of perfringolysin O is an essential cholestereol-binding unit targeting to cholesterol-rich microdomains
    • Shimada Y, Maruya M, Iwashita S, Ohno-Iwashita Y. The C-terminal domain of perfringolysin O is an essential cholestereol-binding unit targeting to cholesterol-rich microdomains. Eur J Biochem 2002, 269:6195-6203.
    • (2002) Eur J Biochem , vol.269 , pp. 6195-6203
    • Shimada, Y.1    Maruya, M.2    Iwashita, S.3    Ohno-Iwashita, Y.4
  • 34
    • 0026785987 scopus 로고
    • Effect of lipidic factors on membrane cholesterol topology - mode of binding of theta-toxin to cholesterol in liposomes
    • Ohno-Iwashita Y, Iwamoto M, Ando S, Iwashita S. Effect of lipidic factors on membrane cholesterol topology - mode of binding of theta-toxin to cholesterol in liposomes. Biochim Biophys Acta 1992, 1109:81-90.
    • (1992) Biochim Biophys Acta , vol.1109 , pp. 81-90
    • Ohno-Iwashita, Y.1    Iwamoto, M.2    Ando, S.3    Iwashita, S.4
  • 35
    • 0035942169 scopus 로고    scopus 로고
    • Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts)
    • Waheed AA, Shimada Y, Heijinen HFG. Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts). Proc Natl Acad Sci USA 2001, 98:4926-4931.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4926-4931
    • Waheed, A.A.1    Shimada, Y.2    Heijinen, H.F.G.3
  • 36
    • 0030865913 scopus 로고    scopus 로고
    • Cross-linked plasmalemmal cholesterol is sequestered to caveolae: analysis with a new cytochemical probe
    • Fujimoto T, Hayashi M, Iwamoto M, Ohno-Iwashita Y. Cross-linked plasmalemmal cholesterol is sequestered to caveolae: analysis with a new cytochemical probe. J Histochem Cytochem 1997, 45:1197-1205.
    • (1997) J Histochem Cytochem , vol.45 , pp. 1197-1205
    • Fujimoto, T.1    Hayashi, M.2    Iwamoto, M.3    Ohno-Iwashita, Y.4
  • 38
    • 0036144685 scopus 로고    scopus 로고
    • Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O
    • Möbius W, Ohno-Iwashita Y, van Donselaar EG. Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O. J Histochem Cytochem 2002, 50:43-55.
    • (2002) J Histochem Cytochem , vol.50 , pp. 43-55
    • Möbius, W.1    Ohno-Iwashita, Y.2    van Donselaar, E.G.3
  • 39
    • 26444510888 scopus 로고    scopus 로고
    • Structure and funtion of lipid rafts in human activated T cells
    • Tani-ichi S, Maruyama K, Kondo N. Structure and funtion of lipid rafts in human activated T cells. Int Immunol 2005, 17:749-758.
    • (2005) Int Immunol , vol.17 , pp. 749-758
    • Tani-ichi, S.1    Maruyama, K.2    Kondo, N.3
  • 40
    • 4944244476 scopus 로고    scopus 로고
    • Axon-dominant localization of cell-surface cholesterol in cultured hippocampal neurons and its disappearance in Niemann-Pick type C model cells
    • Tashiro Y, Yamazaki T, Shimada Y, Ohno-Iwashita Y, Okamoto K. Axon-dominant localization of cell-surface cholesterol in cultured hippocampal neurons and its disappearance in Niemann-Pick type C model cells. Eur J Neurosci 2004, 20:2015-2021.
    • (2004) Eur J Neurosci , vol.20 , pp. 2015-2021
    • Tashiro, Y.1    Yamazaki, T.2    Shimada, Y.3    Ohno-Iwashita, Y.4    Okamoto, K.5
  • 41
    • 11144223256 scopus 로고    scopus 로고
    • Distinct localization of lipid rafts and externalized phosphatidylserine at the surface of apoptotic cells
    • Ishii H, Mori T, Shiratsuchi A. Distinct localization of lipid rafts and externalized phosphatidylserine at the surface of apoptotic cells. Biochem Biophys Res Commun 2005, 327:94-99.
    • (2005) Biochem Biophys Res Commun , vol.327 , pp. 94-99
    • Ishii, H.1    Mori, T.2    Shiratsuchi, A.3
  • 42
    • 33846883295 scopus 로고    scopus 로고
    • Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-alpha secretion in ABCa1-deficient macrophages
    • Koseki M, Hirano K, Masuda D. Increased lipid rafts and accelerated lipopolysaccharide-induced tumor necrosis factor-alpha secretion in ABCa1-deficient macrophages. J Lipid Res 2007, 48:299-306.
    • (2007) J Lipid Res , vol.48 , pp. 299-306
    • Koseki, M.1    Hirano, K.2    Masuda, D.3
  • 43
    • 0141590704 scopus 로고    scopus 로고
    • Biotinylated θ-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells
    • Sugii S, Reid PC, Ohgami N. Biotinylated θ-toxin derivative as a probe to examine intracellular cholesterol-rich domains in normal and Niemann-Pick type C1 cells. J Lipid Res 2003, 44:1033-1041.
    • (2003) J Lipid Res , vol.44 , pp. 1033-1041
    • Sugii, S.1    Reid, P.C.2    Ohgami, N.3
  • 44
    • 0345275891 scopus 로고    scopus 로고
    • Gamma-secretase activity is present in rafts but is not cholesterol-dependent
    • Wada S, Morishima-Kawashima M, Qi Y. Gamma-secretase activity is present in rafts but is not cholesterol-dependent. Biochemistry 2003, 42:13977-13986.
    • (2003) Biochemistry , vol.42 , pp. 13977-13986
    • Wada, S.1    Morishima-Kawashima, M.2    Qi, Y.3
  • 45
    • 2542493177 scopus 로고    scopus 로고
    • Distribution and transport of cholesterol-rich membrane domains monitored by a membrane-impermeant fluorescent polyethylene glycol-derivatized cholesterol
    • Sato SB, Ishii K, Makino A. Distribution and transport of cholesterol-rich membrane domains monitored by a membrane-impermeant fluorescent polyethylene glycol-derivatized cholesterol. J Biol Chem 2004, 279:23790-23796.
    • (2004) J Biol Chem , vol.279 , pp. 23790-23796
    • Sato, S.B.1    Ishii, K.2    Makino, A.3
  • 46
    • 3142706505 scopus 로고    scopus 로고
    • T-lymphocyte signaling in systemic lupus erythematosus: a lipid raft perspective
    • Jury EC, Kabouridis PS. T-lymphocyte signaling in systemic lupus erythematosus: a lipid raft perspective. Lupus 2004, 13:413-422.
    • (2004) Lupus , vol.13 , pp. 413-422
    • Jury, E.C.1    Kabouridis, P.S.2
  • 47
    • 0034988887 scopus 로고    scopus 로고
    • Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane
    • Lusa S, Blom TS, Eskelinen E-L. Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane. J Cell Sci 2001, 114:1893-1900.
    • (2001) J Cell Sci , vol.114 , pp. 1893-1900
    • Lusa, S.1    Blom, T.S.2    Eskelinen, E.-L.3
  • 48
    • 0037376341 scopus 로고    scopus 로고
    • Storage diseases: new insights into sphingolipid functions
    • Sillence DJ, Platt FM. Storage diseases: new insights into sphingolipid functions. Trends Cell Biol 2003, 13:195-203.
    • (2003) Trends Cell Biol , vol.13 , pp. 195-203
    • Sillence, D.J.1    Platt, F.M.2
  • 49
    • 3943092621 scopus 로고    scopus 로고
    • Pathways towards and away from Alzheimer's disease
    • Mattson MP. Pathways towards and away from Alzheimer's disease. Nature 2004, 430:631-639.
    • (2004) Nature , vol.430 , pp. 631-639
    • Mattson, M.P.1
  • 50
    • 0035928732 scopus 로고    scopus 로고
    • Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts
    • Riddell DR, Christie G, Hussain I, Dingwall C. Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts. Curr Biol 2001, 11:1288-1293.
    • (2001) Curr Biol , vol.11 , pp. 1288-1293
    • Riddell, D.R.1    Christie, G.2    Hussain, I.3    Dingwall, C.4
  • 53
    • 0035826909 scopus 로고    scopus 로고
    • Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
    • Kojro E, Gimpl G, Lammich S, Marz W, Fahrenholz F. Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10. Proc Natl Acad Sci USA 2001, 98:5815-5820.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5815-5820
    • Kojro, E.1    Gimpl, G.2    Lammich, S.3    Marz, W.4    Fahrenholz, F.5
  • 54
    • 0037421206 scopus 로고    scopus 로고
    • Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
    • Ehehalt R, Keller P, Haass C, Thiele C, Simons K. Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts. J Cell Biol 2003, 160:113-123.
    • (2003) J Cell Biol , vol.160 , pp. 113-123
    • Ehehalt, R.1    Keller, P.2    Haass, C.3    Thiele, C.4    Simons, K.5
  • 55
    • 10344263931 scopus 로고    scopus 로고
    • Neuronal membrane cholesterol loss enhances amyloid peptide generation
    • Abad-Rodriguez J, Ledesma MD, Craessaerts K. Neuronal membrane cholesterol loss enhances amyloid peptide generation. J Cell Biol 2004, 167:953-960.
    • (2004) J Cell Biol , vol.167 , pp. 953-960
    • Abad-Rodriguez, J.1    Ledesma, M.D.2    Craessaerts, K.3
  • 56
    • 10344226187 scopus 로고    scopus 로고
    • A lipid boundary separates APP and secretases and limits amyloid β-peptide generation
    • Kaether C, Haass C. A lipid boundary separates APP and secretases and limits amyloid β-peptide generation. J Cell Biol 2004, 167:809-812.
    • (2004) J Cell Biol , vol.167 , pp. 809-812
    • Kaether, C.1    Haass, C.2
  • 57
    • 2442664072 scopus 로고    scopus 로고
    • A seed for Alzheimer amyloid in the brain
    • Hayashi H, Kimura N, Yamaguchi H. A seed for Alzheimer amyloid in the brain. J Neurosci 2004, 24:4894-4902.
    • (2004) J Neurosci , vol.24 , pp. 4894-4902
    • Hayashi, H.1    Kimura, N.2    Yamaguchi, H.3
  • 58
    • 0035816709 scopus 로고    scopus 로고
    • Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid
    • Kakio A, Nishimoto S, Yanagisawa K, Kozutsumi Y, Matsuzaki K. Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid. J Biol Chem 2001, 276:24985-24990.
    • (2001) J Biol Chem , vol.276 , pp. 24985-24990
    • Kakio, A.1    Nishimoto, S.2    Yanagisawa, K.3    Kozutsumi, Y.4    Matsuzaki, K.5
  • 59
    • 0029935694 scopus 로고    scopus 로고
    • Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice
    • Igbavboa U, Avdulov NA, Schroeder F, Wood WG. Increasing age alters transbilayer fluidity and cholesterol asymmetry in synaptic plasma membranes of mice. J Neurochem 1996, 66:1717-1725.
    • (1996) J Neurochem , vol.66 , pp. 1717-1725
    • Igbavboa, U.1    Avdulov, N.A.2    Schroeder, F.3    Wood, W.G.4
  • 60
    • 0036786840 scopus 로고    scopus 로고
    • Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I
    • Frank PG, Marcel YL, Connelly MA. Stabilization of caveolin-1 by cellular cholesterol and scavenger receptor class B type I. Biochemistry 2002, 41:11931-11940.
    • (2002) Biochemistry , vol.41 , pp. 11931-11940
    • Frank, P.G.1    Marcel, Y.L.2    Connelly, M.A.3
  • 62
    • 0032813808 scopus 로고    scopus 로고
    • Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
    • Brooks-Wilson A, Marcil M, Clee SM. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet 1999, 22:336-345.
    • (1999) Nat Genet , vol.22 , pp. 336-345
    • Brooks-Wilson, A.1    Marcil, M.2    Clee, S.M.3
  • 63
    • 33845971925 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A-1 expression disrupts raft membrane microdomains through its ATPase-related functions
    • Landry YD, Denis M, Nandi S, Bell S, Vaughan AM, Zha X. ATP-binding cassette transporter A-1 expression disrupts raft membrane microdomains through its ATPase-related functions. J Biol Chem 2006, 281:36091-36101.
    • (2006) J Biol Chem , vol.281 , pp. 36091-36101
    • Landry, Y.D.1    Denis, M.2    Nandi, S.3    Bell, S.4    Vaughan, A.M.5    Zha, X.6
  • 64
    • 0042570843 scopus 로고    scopus 로고
    • Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
    • Virkamäki A, Ueki K, Kahn CR. Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 1999, 103:931-943.
    • (1999) J Clin Invest , vol.103 , pp. 931-943
    • Virkamäki, A.1    Ueki, K.2    Kahn, C.R.3
  • 66
    • 33746725988 scopus 로고    scopus 로고
    • Insulin resistence as a membrane microdomain disorder
    • Inokuchi J. Insulin resistence as a membrane microdomain disorder. Biol Pharm Bull 2006, 29:1532-1537.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1532-1537
    • Inokuchi, J.1
  • 67
    • 0038757868 scopus 로고    scopus 로고
    • Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection
    • Manes S, del Real G, Lacalle RA. Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection. EMBO Rep 2000, 1:190-196.
    • (2000) EMBO Rep , vol.1 , pp. 190-196
    • Manes, S.1    del Real, G.2    Lacalle, R.A.3
  • 68
    • 0032996508 scopus 로고    scopus 로고
    • Exploitation of major histocompatibility complex class I molecules and caveolae by simian virus 40
    • Parton RG, Lindsay M. Exploitation of major histocompatibility complex class I molecules and caveolae by simian virus 40. Immunol Rev 1999, 168:23-31.
    • (1999) Immunol Rev , vol.168 , pp. 23-31
    • Parton, R.G.1    Lindsay, M.2
  • 69
    • 0033995067 scopus 로고    scopus 로고
    • Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins
    • Zhang J, Pekosz A, Lamb RA. Influenza virus assembly and lipid raft microdomains: a role for the cytoplasmic tails of the spike glycoproteins. J Virol 2000, 74:4634-4644.
    • (2000) J Virol , vol.74 , pp. 4634-4644
    • Zhang, J.1    Pekosz, A.2    Lamb, R.A.3
  • 71
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25:585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 72
    • 4644250302 scopus 로고    scopus 로고
    • From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing
    • Magalhaes JP. From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing. Exp Cell Res 2004, 300:1-10.
    • (2004) Exp Cell Res , vol.300 , pp. 1-10
    • Magalhaes, J.P.1
  • 73
    • 0030025660 scopus 로고    scopus 로고
    • Replicative senescence: an old lives' tale?
    • Campisi J. Replicative senescence: an old lives' tale? Cell 1996, 84:497-500.
    • (1996) Cell , vol.84 , pp. 497-500
    • Campisi, J.1
  • 74
    • 0042346366 scopus 로고    scopus 로고
    • Senescent phenotype can be reversed by reduction of caveolin status
    • Cho KA, Ryu SJ, Park JS. Senescent phenotype can be reversed by reduction of caveolin status. J Biol Chem 2003, 278:27789-27795.
    • (2003) J Biol Chem , vol.278 , pp. 27789-27795
    • Cho, K.A.1    Ryu, S.J.2    Park, J.S.3
  • 75
    • 4744371424 scopus 로고    scopus 로고
    • Morphological adjustment of senescent cells by modulating caveolin-1 status
    • Cho KA, Ryu SJ, Oh YS. Morphological adjustment of senescent cells by modulating caveolin-1 status. J Biol Chem 2004, 279:42270-42278.
    • (2004) J Biol Chem , vol.279 , pp. 42270-42278
    • Cho, K.A.1    Ryu, S.J.2    Oh, Y.S.3
  • 76
    • 0032577647 scopus 로고    scopus 로고
    • Caveolin-mediated regulation of signalling along the p42/44 MAP kinase cascade in vivo
    • Engelman JA, Chu C, Lin A. Caveolin-mediated regulation of signalling along the p42/44 MAP kinase cascade in vivo. FEBS Lett 1998, 428:205-211.
    • (1998) FEBS Lett , vol.428 , pp. 205-211
    • Engelman, J.A.1    Chu, C.2    Lin, A.3
  • 77
    • 0032483575 scopus 로고
    • A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth
    • Wary KK, Mariotti A, Zurzolo C, Giancotti FG. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 1988, 94:625-634.
    • (1988) Cell , vol.94 , pp. 625-634
    • Wary, K.K.1    Mariotti, A.2    Zurzolo, C.3    Giancotti, F.G.4
  • 80
    • 0242624574 scopus 로고    scopus 로고
    • Ageing, autoimmunity and arthritis: perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system
    • Fülöp T, Larbi A, Dupuis G, Pawelec G. Ageing, autoimmunity and arthritis: perturbations of TCR signal transduction pathways with ageing - a biochemical paradigm for the ageing immune system. Arthritis Res Ther 2003, 5:290-302.
    • (2003) Arthritis Res Ther , vol.5 , pp. 290-302
    • Fülöp, T.1    Larbi, A.2    Dupuis, G.3    Pawelec, G.4
  • 81
    • 0033865177 scopus 로고    scopus 로고
    • Molecular mechanism of the impairment in activation signal transduction in CD4+ T cells from old mice
    • Tamura T, Kunimatsu T, Yee S-T. Molecular mechanism of the impairment in activation signal transduction in CD4+ T cells from old mice. Int Immunol 2000, 12:1205-1215.
    • (2000) Int Immunol , vol.12 , pp. 1205-1215
    • Tamura, T.1    Kunimatsu, T.2    Yee, S.-T.3
  • 82
    • 3142682595 scopus 로고    scopus 로고
    • T cell receptor signaling: beyond complex complexes
    • Huang Y, Wange RL. T cell receptor signaling: beyond complex complexes. J Biol Chem 2004, 279:28827-28830.
    • (2004) J Biol Chem , vol.279 , pp. 28827-28830
    • Huang, Y.1    Wange, R.L.2
  • 84
  • 85
    • 0035203504 scopus 로고    scopus 로고
    • The role of lipid rafts in signalling and membrane trafficking in T lymphocytes
    • Alonso MA, Millan J. The role of lipid rafts in signalling and membrane trafficking in T lymphocytes. J Cell Sci 2001, 114:3957-3965.
    • (2001) J Cell Sci , vol.114 , pp. 3957-3965
    • Alonso, M.A.1    Millan, J.2
  • 86
    • 0037392883 scopus 로고    scopus 로고
    • Positive and negative regulation in T-cell activation through kinases and phosphatases
    • Mustelin T, Tasken K. Positive and negative regulation in T-cell activation through kinases and phosphatases. Biochem J 2003, 371:15-27.
    • (2003) Biochem J , vol.371 , pp. 15-27
    • Mustelin, T.1    Tasken, K.2
  • 87
    • 0032498231 scopus 로고    scopus 로고
    • LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
    • Zhang W, Sloan-Lancaster J, Kitchen L, Trible RP, Samelson LE. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92:83-92.
    • (1998) Cell , vol.92 , pp. 83-92
    • Zhang, W.1    Sloan-Lancaster, J.2    Kitchen, L.3    Trible, R.P.4    Samelson, L.E.5
  • 88
    • 0026355723 scopus 로고
    • CSK: a protein- tyrosine kinase involved in regulation of src family kinases
    • Okada M, Nada S, Yamanashi Y, Yamamoto T, Nakagawa H. CSK: a protein- tyrosine kinase involved in regulation of src family kinases. J Biol Chem 1991, 266:24249-24252.
    • (1991) J Biol Chem , vol.266 , pp. 24249-24252
    • Okada, M.1    Nada, S.2    Yamanashi, Y.3    Yamamoto, T.4    Nakagawa, H.5
  • 89
    • 0342313755 scopus 로고    scopus 로고
    • Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
    • Brdicka T, Pavlistova D, Leo A. Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 2000, 191:1591-1604.
    • (2000) J Exp Med , vol.191 , pp. 1591-1604
    • Brdicka, T.1    Pavlistova, D.2    Leo, A.3
  • 90
    • 0034720166 scopus 로고    scopus 로고
    • Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
    • Kawabuchi M, Satomi Y, Takao T. Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 2000, 404:999-1003.
    • (2000) Nature , vol.404 , pp. 999-1003
    • Kawabuchi, M.1    Satomi, Y.2    Takao, T.3
  • 91
    • 0037105622 scopus 로고    scopus 로고
    • Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells
    • Yasuda K, Nagafuku M, Shima T. Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells. J Immunol 2002, 169:2813-2817.
    • (2002) J Immunol , vol.169 , pp. 2813-2817
    • Yasuda, K.1    Nagafuku, M.2    Shima, T.3
  • 92
    • 0036143017 scopus 로고    scopus 로고
    • Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases
    • Hermiston ML, Xu Z, Majeti R, Weiss A. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J Clin Invest 2002, 109:9-14.
    • (2002) J Clin Invest , vol.109 , pp. 9-14
    • Hermiston, M.L.1    Xu, Z.2    Majeti, R.3    Weiss, A.4
  • 93
    • 0037370491 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor
    • Davidson D, Bakinowski M, Thomas ML, Horejsi V, Veillette A. Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor. Mol Cell Biol 2003, 23:2017-2028.
    • (2003) Mol Cell Biol , vol.23 , pp. 2017-2028
    • Davidson, D.1    Bakinowski, M.2    Thomas, M.L.3    Horejsi, V.4    Veillette, A.5
  • 94
    • 33645102374 scopus 로고    scopus 로고
    • Differential role of lipid rafts in the functions of CD4+ and CD8+ human T lymphocytes with aging
    • Larbi A, Dupuis G, Khalil A, Douziech N, Fortin C, Fülöp T. Differential role of lipid rafts in the functions of CD4+ and CD8+ human T lymphocytes with aging. Cell Signal 2006, 18:1017-1030.
    • (2006) Cell Signal , vol.18 , pp. 1017-1030
    • Larbi, A.1    Dupuis, G.2    Khalil, A.3    Douziech, N.4    Fortin, C.5    Fülöp, T.6
  • 95
    • 0033000068 scopus 로고    scopus 로고
    • Age-related impairment of p56lck and ZAP-70 activities in human T lymphocytes activated through the TcR/CD3 complex
    • Fülöp T, Gagne D, Goulet A-C. Age-related impairment of p56lck and ZAP-70 activities in human T lymphocytes activated through the TcR/CD3 complex. Exp Gerontol 1999, 34:197-216.
    • (1999) Exp Gerontol , vol.34 , pp. 197-216
    • Fülöp, T.1    Gagne, D.2    Goulet, A.-C.3
  • 96
    • 0030800053 scopus 로고    scopus 로고
    • Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex
    • Whisler RL, Bagenstose SE, Newhouse YG, Carle KW. Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex. Mech Ageing Dev 1997, 98:57-73.
    • (1997) Mech Ageing Dev , vol.98 , pp. 57-73
    • Whisler, R.L.1    Bagenstose, S.E.2    Newhouse, Y.G.3    Carle, K.W.4
  • 97
    • 34250222482 scopus 로고    scopus 로고
    • Impairment in a negative regulatory system for TCR signaling in CD4+ T cells from old mice
    • Inomata M, Shimada Y, Hayashi M, Shimizu J, Ohno-Iwashita Y. Impairment in a negative regulatory system for TCR signaling in CD4+ T cells from old mice. FEBS Lett 2007, 581:3039-3043.
    • (2007) FEBS Lett , vol.581 , pp. 3039-3043
    • Inomata, M.1    Shimada, Y.2    Hayashi, M.3    Shimizu, J.4    Ohno-Iwashita, Y.5
  • 98
    • 0035955452 scopus 로고    scopus 로고
    • Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton
    • Brdickova N, Brdicka T, Andera L. Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeleton. FEBS Lett 2001, 507:133-136.
    • (2001) FEBS Lett , vol.507 , pp. 133-136
    • Brdickova, N.1    Brdicka, T.2    Andera, L.3
  • 99
    • 0037869152 scopus 로고    scopus 로고
    • T cell glycolipid-enrichhed membrane domains are constitutively assembled as membrane patches that translocate to immune synapses
    • Jordan S, Rodgers W. T cell glycolipid-enrichhed membrane domains are constitutively assembled as membrane patches that translocate to immune synapses. J Immunol 2003, 171:78-87.
    • (2003) J Immunol , vol.171 , pp. 78-87
    • Jordan, S.1    Rodgers, W.2
  • 100
    • 0032478816 scopus 로고    scopus 로고
    • Aging-related deficiency of CD28 expression in CD4+ T cells is associated with the loss of gene-specific nuclear factor binding activity
    • Vallejo AN, Nestel AR, Schirmer M, Weyand CM, Goronzy JJ. Aging-related deficiency of CD28 expression in CD4+ T cells is associated with the loss of gene-specific nuclear factor binding activity. J Biol Chem 1998, 273:8119-8129.
    • (1998) J Biol Chem , vol.273 , pp. 8119-8129
    • Vallejo, A.N.1    Nestel, A.R.2    Schirmer, M.3    Weyand, C.M.4    Goronzy, J.J.5
  • 101
    • 33750533178 scopus 로고    scopus 로고
    • CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse
    • Tavano R, Contento RL, Baranda SJ. CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse. Nat Cell Biol 2006, 8:1270-1276.
    • (2006) Nat Cell Biol , vol.8 , pp. 1270-1276
    • Tavano, R.1    Contento, R.L.2    Baranda, S.J.3


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