-
1
-
-
0034914737
-
A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model
-
Asthagiri AR, Lauffenburger DA. 2001. A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model. Biotechnol Prog 17: 227-239.
-
(2001)
Biotechnol. Prog.
, vol.17
, pp. 227-239
-
-
Asthagiri, A.R.1
Lauffenburger, D.A.2
-
2
-
-
0030764540
-
Periplasmic Bar1 protease of Saccharomyces cerevisiae is active before reaching its extracellular destination
-
Ballensiefen W, Schmitt HD. 1997. Periplasmic Bar1 protease of Saccharomyces cerevisiae is active before reaching its extracellular destination. Eur J Biochem 247: 142-147.
-
(1997)
Eur. J. Biochem.
, vol.247
, pp. 142-147
-
-
Ballensiefen, W.1
Schmitt, H.D.2
-
3
-
-
0029992810
-
Signaling in the yeast pheromone response pathway: Specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7
-
Bardwell L, Cook JG Chang EC, Cairns BR, Thorner J. 1996. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Mol Cell Biol 16: 3637-3650.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 3637-3650
-
-
Bardwell, L.1
Cook, J.G.2
Chang, E.C.3
Cairns, B.R.4
Thorner, J.5
-
4
-
-
0032446353
-
Differential regulation of transcription: Repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins
-
Bardwell L, Cook JG, Zhu-Shimoni JX, Voora D, Thorner J. 1998. Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc Natl Acad Sci USA 95: 15 400-15 405.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15400-15405
-
-
Bardwell, L.1
Cook, J.G.2
Zhu-Shimoni, J.X.3
Voora, D.4
Thorner, J.5
-
5
-
-
0030272039
-
A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs
-
Bardwell L, Thorner J. 1996. A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. Trends Biochem Sci 21: 373-374.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 373-374
-
-
Bardwell, L.1
Thorner, J.2
-
6
-
-
0037457896
-
Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system
-
Batchelor E, Goulian M. 2003. Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system. Proc Natl Acad Sci USA 100: 691-696.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 691-696
-
-
Batchelor, E.1
Goulian, M.2
-
7
-
-
0026694917
-
Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator
-
Berstein G, Blank JL, Jhon DY, et al. 1992. Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator. Cell 70: 411-418.
-
(1992)
Cell
, vol.70
, pp. 411-418
-
-
Berstein, G.1
Blank, J.L.2
Jhon, D.Y.3
-
8
-
-
0033555859
-
Emergent properties of networks of biological signaling pathways
-
Bhalla US, Iyengar R. 1999. Emergent properties of networks of biological signaling pathways. Science 283: 381-387.
-
(1999)
Science
, vol.283
, pp. 381-387
-
-
Bhalla, U.S.1
Iyengar, R.2
-
9
-
-
0023680876
-
The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae
-
Blumer KJ, Reneke JE, Thorner J. 1988. The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae. J Biol Chem 263: 10 836-10 842.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 10836-10842
-
-
Blumer, K.J.1
Reneke, J.E.2
Thorner, J.3
-
10
-
-
0025441553
-
β- and γ-subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the a subunit but are required for receptor coupling
-
Blumer KJ, Thorner J. 1990. β- and γ-subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the a subunit but are required for receptor coupling. Proc Natl Acad Sci USA 87: 4363-4367.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 4363-4367
-
-
Blumer, K.J.1
Thorner, J.2
-
11
-
-
0035928744
-
MAPK specificity in the yeast pheromone response independent of transcriptional activation
-
Breitkreutz A, Boucher L, Tyers M. 2001. MAPK specificity in the yeast pheromone response independent of transcriptional activation. Curr Biol 11: 1266-1271.
-
(2001)
Curr. Biol.
, vol.11
, pp. 1266-1271
-
-
Breitkreutz, A.1
Boucher, L.2
Tyers, M.3
-
12
-
-
0036607966
-
MAPK signaling specificity: It takes two to tango
-
Breitkreutz A, Tyers M. 2002. MAPK signaling specificity: it takes two to tango. Trends Cell Biol 12: 254-257.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 254-257
-
-
Breitkreutz, A.1
Tyers, M.2
-
13
-
-
0034009390
-
Signal transduction: Hanging on a scaffold
-
Burack WR, Shaw AS. 2000. Signal transduction: hanging on a scaffold. Curr Opin Cell Biol 12: 211-216.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 211-216
-
-
Burack, W.R.1
Shaw, A.S.2
-
14
-
-
0032553474
-
The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating
-
Butty AC, Pryciak PM, Huang LS, Herskowitz I, Peter M. 1998. The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science 282: 1511-1516.
-
(1998)
Science
, vol.282
, pp. 1511-1516
-
-
Butty, A.C.1
Pryciak, P.M.2
Huang, L.S.3
Herskowitz, I.4
Peter, M.5
-
16
-
-
0033985570
-
Kinetic analysis of a molecular model of the budding yeast cell cycle
-
Chen KC, Csikasz-Nagy A, Gyorffy B, et al. 2000. Kinetic analysis of a molecular model of the budding yeast cell cycle. Mol Biol Cell 11: 369-391.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 369-391
-
-
Chen, K.C.1
Csikasz-Nagy, A.2
Gyorffy, B.3
-
17
-
-
0027983908
-
Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae
-
Choi KY, Satterberg B, Lyons DM, Elion EA. 1994. Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell 78: 499-512.
-
(1994)
Cell
, vol.78
, pp. 499-512
-
-
Choi, K.Y.1
Satterberg, B.2
Lyons, D.M.3
Elion, E.A.4
-
18
-
-
0025019539
-
Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway
-
Cole GM, Stone DE, Reed SI. 1990. Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway. Mol Cell Biol 10: 510-517.
-
(1990)
Mol. Cell Biol.
, vol.10
, pp. 510-517
-
-
Cole, G.M.1
Stone, D.E.2
Reed, S.I.3
-
19
-
-
0027318238
-
Structural elements of Get subunits that interact with G B8, receptors, and effectors
-
Conklin BR, Bourne HR. 1993. Structural elements of Get subunits that interact with G B8, receptors, and effectors. Cell 73: 631-641.
-
(1993)
Cell
, vol.73
, pp. 631-641
-
-
Conklin, B.R.1
Bourne, H.R.2
-
20
-
-
0034114133
-
From genome to cellular phenotype - A role for metabolic flux analysis?
-
Cornish-Bowden A, Cardenas ML. 2000. From genome to cellular phenotype - a role for metabolic flux analysis? Nature Biotechnol 18: 267-268.
-
(2000)
Nature Biotechnol.
, vol.18
, pp. 267-268
-
-
Cornish-Bowden, A.1
Cardenas, M.L.2
-
21
-
-
0035341895
-
The Ste 20 group kinases as regulators of MAP kinase cascades
-
Dan I, Watanabe NM, Kusumi A. 2001. The Ste 20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol 11: 220-230.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 220-230
-
-
Dan, I.1
Watanabe, N.M.2
Kusumi, A.3
-
22
-
-
0023664976
-
The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
-
Dietzel C, Kurjan J. 1987. The yeast SCG1 gene: a Gα-like protein implicated in the a- and α-factor response pathway. Cell 50: 1001-1010.
-
(1987)
Cell
, vol.50
, pp. 1001-1010
-
-
Dietzel, C.1
Kurjan, J.2
-
23
-
-
0036193842
-
G proteins and pheromone signaling
-
Dohlman HG. 2002. G proteins and pheromone signaling. Annu Rev Physiol 64: 129-152.
-
(2002)
Annu. Rev. Physiol.
, vol.64
, pp. 129-152
-
-
Dohlman, H.G.1
-
24
-
-
0031041306
-
RGS proteins and signaling by heterotrimeric G proteins
-
Dohlman HG, Thorner J. 1997. RGS proteins and signaling by heterotrimeric G proteins. J Biol Chem 272: 3871-3874.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3871-3874
-
-
Dohlman, H.G.1
Thorner, J.2
-
25
-
-
0034923514
-
Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
-
Dohlman HG, Thomer JW. 2001. Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annu Rev Biochem 70: 703-754.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 703-754
-
-
Dohlman, H.G.1
Thomer, J.W.2
-
26
-
-
0033647489
-
Pheromone response, mating and cell biology
-
Elion EA. 2000. Pheromone response, mating and cell biology. Curr Opin Microbiol 3: 573-581.
-
(2000)
Curr. Opin. Microbiol.
, vol.3
, pp. 573-581
-
-
Elion, E.A.1
-
27
-
-
0035195491
-
The Ste5p scaffold
-
Elion EA. 2001. The Ste5p scaffold. J Cell Sci 114: 3967-3978.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3967-3978
-
-
Elion, E.A.1
-
28
-
-
0037047096
-
Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism
-
Esch RK, Errede B. 2002. Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism. Proc Natl Acad Sci USA 99: 9160-9165.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9160-9165
-
-
Esch, R.K.1
Errede, B.2
-
30
-
-
0032567815
-
Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11
-
Feng Y, Song LY, Kincaid E, Mahanty SK, Ellon EA. 1998. Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11. Curr Biol 8: 267-278.
-
(1998)
Curr. Biol.
, vol.8
, pp. 267-278
-
-
Feng, Y.1
Song, L.Y.2
Kincaid, E.3
Mahanty, S.K.4
Ellon, E.A.5
-
31
-
-
0036532226
-
Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
-
Ferrell JE Jr. 2002. Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol 14: 140-148.
-
(2002)
Curr. Opin. Cell Biol.
, vol.14
, pp. 140-148
-
-
Ferrell Jr., J.E.1
-
32
-
-
0030746219
-
Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase
-
Ferrell JE Jr, Bhatt RR. 1997. Mechanistic studies of the dual phosphorylation of mitogen-activated protein kinase. J Biol Chem 272: 19 008-19016.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19008-19016
-
-
Ferrell Jr., J.E.1
Bhatt, R.R.2
-
33
-
-
0032557490
-
Molecular basis for interactions of G protein βγ subunits with effectors
-
Ford CE, Skiba NP, Bae H, et al. 1998. Molecular basis for interactions of G protein βγ subunits with effectors. Science 280: 1271-1274.
-
(1998)
Science
, vol.280
, pp. 1271-1274
-
-
Ford, C.E.1
Skiba, N.P.2
Bae, H.3
-
34
-
-
0031595259
-
1 cell cycle arrest requires Far 1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo
-
1 cell cycle arrest requires Far 1 phosphorylation, but may not involve inhibition of Cdc28-Cln2 kinase, in vivo. Mol Cell Biol 18: 3681-3691.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3681-3691
-
-
Gartner, A.1
Jovanovic, A.2
Jeoung, D.I.3
-
36
-
-
0344012556
-
Regulators of G protein signaling and transient activation of signaling: Experimental and computational analysis reveals negative and positive feedback controls on G protein activity
-
Hao N, Yildirim N, Wang Y, Elston TC, Dohlman HG. 2003. Regulators of G protein signaling and transient activation of signaling: experimental and computational analysis reveals negative and positive feedback controls on G protein activity. J Biol Chem 278: 46 506-46 515.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46506-46515
-
-
Hao, N.1
Yildirim, N.2
Wang, Y.3
Elston, T.C.4
Dohlman, H.G.5
-
37
-
-
0036285634
-
Mathematical models of protein kinase signal transduction
-
Heinrich R, Neel BG, Rapoport TA. 2002. Mathematical models of protein kinase signal transduction. Mol Cell 9: 957-970.
-
(2002)
Mol. Cell
, vol.9
, pp. 957-970
-
-
Heinrich, R.1
Neel, B.G.2
Rapoport, T.A.3
-
39
-
-
0030693702
-
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far 1p in budding yeast
-
Henchoz S, Chi Y, Catarin B, et al. 1997. Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far 1p in budding yeast. Genes Dev 11: 3046-3060.
-
(1997)
Genes Dev.
, vol.11
, pp. 3046-3060
-
-
Henchoz, S.1
Chi, Y.2
Catarin, B.3
-
40
-
-
0030614451
-
The Gβγ complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions
-
Hirschman JE, De Zutter GS, Simonds WF, Jenness DD. 1997. The Gβγ complex of the yeast pheromone response pathway. Subcellular fractionation and protein-protein interactions. J Biol Chem 272: 240-248.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 240-248
-
-
Hirschman, J.E.1
De Zutter, G.S.2
Simonds, W.F.3
Jenness, D.D.4
-
41
-
-
0029790351
-
Ultrasensitivity in the mitogen-activated protein kinase cascade
-
Huang CY, Ferrell JE Jr. 1996. Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc Natl Acad Sci USA 93: 10 078-10 083.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10078-10083
-
-
Huang, C.Y.1
Ferrell Jr., J.E.2
-
42
-
-
0030777328
-
Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: Application of a differential interaction trap assay for examining protein-protein interactions
-
Inouye C, Dhillon N, Durfee T, Zambryski PC, Thorner J. 1997a. Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics 147: 479-492.
-
(1997)
Genetics
, vol.147
, pp. 479-492
-
-
Inouye, C.1
Dhillon, N.2
Durfee, T.3
Zambryski, P.C.4
Thorner, J.5
-
43
-
-
0030815533
-
Ste5 RING-H2 domain: Role in Ste4-promoted oligomerization for yeast pheromone signaling
-
Inouye C, Dhillon N, Thorner J. 1997b. Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling. Science 278: 103-106.
-
(1997)
Science
, vol.278
, pp. 103-106
-
-
Inouye, C.1
Dhillon, N.2
Thorner, J.3
-
44
-
-
0034019315
-
Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades
-
Kholodenko BN. 2000. Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades. Eur J Biochem 267: 1583-1588.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 1583-1588
-
-
Kholodenko, B.N.1
-
45
-
-
0028057744
-
The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5
-
Kranz JE, Satterberg B, Elion EA. 1994. The MAP kinase Fus3 associates with and phosphorylates the upstream signaling component Ste5. Genes Dev 8: 313-327.
-
(1994)
Genes Dev.
, vol.8
, pp. 313-327
-
-
Kranz, J.E.1
Satterberg, B.2
Elion, E.A.3
-
46
-
-
0026637326
-
Pheromone response in yeast
-
Kurjan J. 1992. Pheromone response in yeast. Anna Rev Biochem 61: 1097-1129.
-
(1992)
Anna. Rev. Biochem.
, vol.61
, pp. 1097-1129
-
-
Kurjan, J.1
-
47
-
-
0034721832
-
Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Gαi and Gαo deactivation. Gα specificity of RGS4 AND RGS7
-
Lan KL, Zhong H, Nanamori M, Neubig RR. 2000. Rapid kinetics of regulator of G-protein signaling (RGS)-mediated Gαi and Gα o deactivation. Gα specificity of RGS4 AND RGS7 J Biol Chem 275: 33 497-33 503.
-
(2000)
J. Biol Chem.
, vol.275
, pp. 33497-33503
-
-
Lan, K.L.1
Zhong, H.2
Nanamori, M.3
Neubig, R.R.4
-
48
-
-
0032495478
-
Interaction of a G-protein P-subunit with a conserved sequence in Ste20/PAK family protein kinases
-
Leeuw T, Wu C, Schrag JD, et al. 1998. Interaction of a G-protein P-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature 391: 191-195.
-
(1998)
Nature
, vol.391
, pp. 191-195
-
-
Leeuw, T.1
Wu, C.2
Schrag, J.D.3
-
49
-
-
0034705227
-
Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties
-
Levchenko A, Bruck L, Sternberg PW. 2000. Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties. Proc Natl Acad Sci USA 97: 5818-5823.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5818-5823
-
-
Levchenko, A.1
Bruck, L.2
Sternberg, P.W.3
-
50
-
-
0031972043
-
Substitutions in the pheromone-responsive Gβ protein of Saccharomyces cerevisiae confer a defect in recovery from pheromone treatment
-
Li E, Meldrum E, Stratton HF, Stone DE. 1998. Substitutions in the pheromone-responsive Gβ protein of Saccharomyces cerevisiae confer a defect in recovery from pheromone treatment. Genetics 148: 947-961.
-
(1998)
Genetics
, vol.148
, pp. 947-961
-
-
Li, E.1
Meldrum, E.2
Stratton, H.F.3
Stone, D.E.4
-
51
-
-
0342901749
-
Generalization of the theory of transition times in metabolic pathways: A geometrical approach
-
Llorens M, Nuno JC, Rodriguez Y, Melendez-Hevia E, Montero F. 1999. Generalization of the theory of transition times in metabolic pathways: a geometrical approach. Biophys J 77: 23-36.
-
(1999)
Biophys. J.
, vol.77
, pp. 23-36
-
-
Llorens, M.1
Nuno, J.C.2
Rodriguez, Y.3
Melendez-Hevia, E.4
Montero, F.5
-
52
-
-
0031977016
-
The riddle of MAP kinase signaling specificity
-
Madhani HD, Fink GR. 1998. The riddle of MAP kinase signaling specificity. Trends Genet 14: 151-155.
-
(1998)
Trends Genet.
, vol.14
, pp. 151-155
-
-
Madhani, H.D.1
Fink, G.R.2
-
53
-
-
0034098922
-
Dual lipid modification motifs in G(α) and G(γ) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae
-
Manahan CL, Patnana M, Blumer KJ, Linder ME. 2000. Dual lipid modification motifs in G(α) and G(γ) subunits are required for full activity of the pheromone response pathway in Saccharomyces cerevisiae. Mol Biol Cell 11: 957-968.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 957-968
-
-
Manahan, C.L.1
Patnana, M.2
Blumer, K.J.3
Linder, M.E.4
-
54
-
-
0027991228
-
Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module
-
Marcus S, Polverino A, Barr M, Wigler M. 1994. Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci USA 91: 7762-7766.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7762-7766
-
-
Marcus, S.1
Polverino, A.2
Barr, M.3
Wigler, M.4
-
55
-
-
0037165954
-
Regulation of MAPK function by direct interaction with the mating-specific Gα in yeast
-
Metodiev MV, Matheos D, Rose MD, Stone DE. 2002. Regulation of MAPK function by direct interaction with the mating-specific Gα in yeast. Science 296: 1483-1486.
-
(2002)
Science
, vol.296
, pp. 1483-1486
-
-
Metodiev, M.V.1
Matheos, D.2
Rose, M.D.3
Stone, D.E.4
-
56
-
-
0033578385
-
Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins
-
Mukhopadhyay S, Ross EM. 1999. Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. Proc Natl Acad Sci USA 96: 9539-9544.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9539-9544
-
-
Mukhopadhyay, S.1
Ross, E.M.2
-
57
-
-
0028261404
-
Reconstitution of a yeast protein kinase cascade in vitro: Activation of the yeast MEK homologue STE7 by STE11
-
Neiman AM, Herskowitz I. 1994. Reconstitution of a yeast protein kinase cascade in vitro: activation of the yeast MEK homologue STE7 by STE11. Proc Natl Acad Sci USA 91: 3398-3402.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3398-3402
-
-
Neiman, A.M.1
Herskowitz, I.2
-
58
-
-
0033593974
-
A Cdc24p-Far1p-G βγ protein complex required for yeast orientation during mating
-
Nern A, Arkowitz RA. 1999. A Cdc24p-Far1p-G βγ protein complex required for yeast orientation during mating. J Cell Biol 144: 1187-1202.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 1187-1202
-
-
Nern, A.1
Arkowitz, R.A.2
-
59
-
-
0029982344
-
Ste12 and Mcm1 regulate cell cycle-dependent transcription of FAR1
-
Oehlen LJ, McKinney JD, Cross FR. 1996. Ste12 and Mcm1 regulate cell cycle-dependent transcription of FAR1. Mol Cell Biol 16: 2830-2837.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 2830-2837
-
-
Oehlen, L.J.1
McKinney, J.D.2
Cross, F.R.3
-
60
-
-
0027191189
-
FARI links the signal transduction pathway to the cell cycle machinery in yeast
-
Peter M, Gartner A, Horecka J, Ammeter G, Herskowitz I. 1993. FARI links the signal transduction pathway to the cell cycle machinery in yeast. Cell 73: 747-760.
-
(1993)
Cell
, vol.73
, pp. 747-760
-
-
Peter, M.1
Gartner, A.2
Horecka, J.3
Ammeter, G.4
Herskowitz, I.5
-
61
-
-
0030832043
-
Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p
-
Pi H, Chien CT, Fields S. 1997. Transcriptional activation upon pheromone stimulation mediated by a small domain of Saccharomyces cerevisiae Ste12p. Mol Cell Biol 17: 6410-6418.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 6410-6418
-
-
Pi, H.1
Chien, C.T.2
Fields, S.3
-
62
-
-
0028046412
-
Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
-
Printen JA, Sprague GF Jr. 1994. Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138: 609-619.
-
(1994)
Genetics
, vol.138
, pp. 609-619
-
-
Printen, J.A.1
Sprague Jr., G.F.2
-
63
-
-
0035798540
-
The complete pathway for catalytic activation of the mitogen-activated protein kinase, ERK2
-
Prowse CN, Deal MS, Lew J. 2001. The complete pathway for catalytic activation of the mitogen-activated protein kinase, ERK2. J Biol Chem 276: 40 817-40 823.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40817-40823
-
-
Prowse, C.N.1
Deal, M.S.2
Lew, J.3
-
64
-
-
0032168881
-
Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway
-
Pryciak PM, Huntress FA. 1998. Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway. Genes Dev 12: 2684-2697.
-
(1998)
Genes Dev.
, vol.12
, pp. 2684-2697
-
-
Pryciak, P.M.1
Huntress, F.A.2
-
65
-
-
0017730006
-
Regulation of mating in the cell cycle of Saccharomyces cerevisiae
-
Reid BI, Hartwell LH. 1977. Regulation of mating in the cell cycle of Saccharomyces cerevisiae. J Cell Biol 75: 355-365.
-
(1977)
J. Cell Biol.
, vol.75
, pp. 355-365
-
-
Reid, B.I.1
Hartwell, L.H.2
-
66
-
-
0033739255
-
Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein
-
Sette C, Inouye CJ, Stroschein SL, Iaquinta PI, Thorner J. 2000. Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol Biol Cell 11: 4033-4049.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 4033-4049
-
-
Sette, C.1
Inouye, C.J.2
Stroschein, S.L.3
Iaquinta, P.I.4
Thorner, J.5
-
67
-
-
0035798633
-
Molecular interactions of the Gβ binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gβ binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy
-
Song J, Chen Z, Xu P, et al. 2001. Molecular interactions of the Gβ binding domain of the Ste20p/PAK family of protein kinases. An isolated but fully functional Gβ binding domain from Ste20p is only partially folded as shown by heteronuclear NMR spectroscopy. J Biol Chem 276: 41 205-41212.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41205-41212
-
-
Song, J.1
Chen, Z.2
Xu, P.3
-
68
-
-
0031128205
-
Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates
-
Tedford K, Kim S, Sa D, Stevens K, Tyers M. 1997. Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr Biol 7: 228-238.
-
(1997)
Curr. Biol.
, vol.7
, pp. 228-238
-
-
Tedford, K.1
Kim, S.2
Sa, D.3
Stevens, K.4
Tyers, M.5
-
70
-
-
0034213955
-
Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo
-
van Drogen F, O'Rourke SM, Stucke VM, et al. 2000. Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signaling in vivo. Curr Biol 10: 630-639.
-
(2000)
Curr. Biol.
, vol.10
, pp. 630-639
-
-
van Drogen, F.1
O'Rourke, S.M.2
Stucke, V.M.3
-
71
-
-
0034752723
-
MAP kinase dynamics in yeast
-
van Drogen F, Peter M. 2001. MAP kinase dynamics in yeast. Biol Cell 93: 63-70.
-
(2001)
Biol. Cell
, vol.93
, pp. 63-70
-
-
van Drogen, F.1
Peter, M.2
-
73
-
-
0033928677
-
Response of Saccharomyces cerevisiae to severe osmotic stress: Evidence for a novel activation mechanism of the HOG MAP kinase pathway
-
Van Wuytswinkel O, Reiser V, Siderius M, et al. 2000. Response of Saccharomyces cerevisiae to severe osmotic stress: evidence for a novel activation mechanism of the HOG MAP kinase pathway. Mol Microbiol 37: 382-397.
-
(2000)
Mol. Microbiol.
, vol.37
, pp. 382-397
-
-
Van Wuytswinkel, O.1
Reiser, V.2
Siderius, M.3
-
74
-
-
0037013202
-
Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7
-
Wang Y, Dohlman HG. 2002. Pheromone-dependent ubiquitination of the mitogen-activated protein kinase kinase Ste7. J Biol Chem 277: 15 766-15 772.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15766-15772
-
-
Wang, Y.1
Dohlman, H.G.2
-
75
-
-
0029146796
-
Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p
-
Whiteway MS, Wu C, Leeuw T, et al. 1995. Association of the yeast pheromone response G protein βγ subunits with the MAP kinase scaffold Ste5p. Science 269: 1572-1575.
-
(1995)
Science
, vol.269
, pp. 1572-1575
-
-
Whiteway, M.S.1
Wu, C.2
Leeuw, T.3
-
76
-
-
0029999863
-
Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae
-
Xu G, Jansen G, Thomas DY, Hollenberg CP, Ramezani Rad M. 1996. Ste50p sustains mating pheromone-induced signal transduction in the yeast Saccharomyces cerevisiae. Mol Microbiol 20: 773-783.
-
(1996)
Mol. Microbiol.
, vol.20
, pp. 773-783
-
-
Xu, G.1
Jansen, G.2
Thomas, D.Y.3
Hollenberg, C.P.4
Ramezani Rad, M.5
-
77
-
-
0030450397
-
Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction
-
Yablonski D, Marbach I, Levitzki A. 1996. Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction. Proc Natl Acad Sci USA 93: 13 864-13 869.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13864-13869
-
-
Yablonski, D.1
Marbach, I.2
Levitzki, A.3
-
78
-
-
0141703270
-
A quantitative characterization of the yeast heterotrimeric G protein cycle
-
Yi TM, Kitano H, Simon MI. 2003. A quantitative characterization of the yeast heterotrimeric G protein cycle. Proc Natl Acad Sci USA 100: 10 764-10 769.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 10764-10769
-
-
Yi, T.M.1
Kitano, H.2
Simon, M.I.3
-
79
-
-
0032748298
-
Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity
-
Zenke FT, King CC, Bohl BP, Bokoch GM. 1999. Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. J Biol Chem 274: 32 565-32 573.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32565-32573
-
-
Zenke, F.T.1
King, C.C.2
Bohl, B.P.3
Bokoch, G.M.4
-
80
-
-
0030820725
-
Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae
-
Zhan XL, Deschenes RI, Guan KL. 1997. Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes Dev 11: 1690-1702.
-
(1997)
Genes Dev.
, vol.11
, pp. 1690-1702
-
-
Zhan, X.L.1
Deschenes, R.I.2
Guan, K.L.3
-
81
-
-
0029118202
-
Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24
-
Zhao ZS, Leung T, Manser E, Lim L. 1995. Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24. Mol Cell Biol 15: 5246-5257.
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 5246-5257
-
-
Zhao, Z.S.1
Leung, T.2
Manser, E.3
Lim, L.4
|