메뉴 건너뛰기




Volumn 18, Issue 28, 2011, Pages 4344-4358

Evaluation of anticonvulsants for possible use in neuropathic pain

Author keywords

Allodynia; Analgesic; Anticonvulsant; CCI; Epilepsy; Hyperalgesia; Neuropathic pain; Preclinical; Seizures; SNL

Indexed keywords

1 [3 [2,5 BIS(TRIFLUOROMETHYL)PHENYL]PHENYL] 5 METHYLPYRAZOLE 3 CARBOXAMIDE; 2 [5 (4 DIMETHYLSULFAMOYLPHENYL) 6,7,8,9 TETRAHYDRO 8 METHYL 2 OXO 1H PYRROLO[3,2 H]ISOQUINOLIN 3 YLIMINOXY] 4 HYDROXYBUTYRIC ACID; 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBONYLUREA; 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBOXAMIDE; ANTICONVULSIVE AGENT; BRIVARACETAM; CARBAMAZEPINE; CNS 5161; DIISOPROPYLACETAMIDE; DULOXETINE; FENPROPATHRIN; GABAPENTIN; HARKOSERIDE; INDANTADOL; LAMOTRIGINE; LIDOCAINE; N METHYL 2,2,3,3 TETRAMETHYLCYCLOPROPANECARBOXAMIDE; NGX 426; NS 479; OXCARBAZEPINE; PREGABALIN; PYRAZOLE DERIVATIVE; RETIGABINE; TEZAMPANEL; TIAGABINE; TOPIRAMATE; UCBL 059; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALNOCTAMIDE; VALPROIC ACID; VALPROIC ACID DERIVATIVE; VALPROMIDE; VALROCEMIDE; VIGABATRIN; ZONISAMIDE;

EID: 80052919231     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711797200408     Document Type: Review
Times cited : (52)

References (165)
  • 1
    • 27944467013 scopus 로고    scopus 로고
    • Algorithm for neuropathic pain treatment: An evidence based proposal
    • DOI 10.1016/j.pain.2005.08.013, PII S0304395905004124
    • Finnerup, N. B.; Otto, M.; McQuay, H. J.; Jensen, T. S.; Sindrup, S. H. Algorithm for neuropathic pain treatment: an evidence based proposal. Pain, 2005, 118, 289-305. (Pubitemid 41752987)
    • (2005) Pain , vol.118 , Issue.3 , pp. 289-305
    • Finnerup, N.B.1    Otto, M.2    McQuay, H.J.3    Jensen, T.S.4    Sindrup, S.H.5
  • 2
  • 10
    • 0010009818 scopus 로고    scopus 로고
    • 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E. Eds., Lippincott Williams & Wilkins: Philadelphia
    • White, S. H.; Woodhead, J. H.; Wilcox, K. S.; Kupferberg, H. J.; Wolf, H. H. In: Antiepileptic Drugs, 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E. Eds.; Lippincott Williams & Wilkins: Philadelphia, 2002; pp. 36-48.
    • (2002) Antiepileptic Drugs , pp. 36-48
    • White, S.H.1    Woodhead, J.H.2    Wilcox, K.S.3    Kupferberg, H.J.4    In, H.W.H.5
  • 11
    • 0035840825 scopus 로고    scopus 로고
    • Pathobiology of neuropathic pain
    • DOI 10.1016/S0014-2999(01)01303-6, PII S0014299901013036
    • Zimmermann, M. Pathobiology of neuropathic pain. Eur. J. Pharmacol., 2001, 429, 23-37. (Pubitemid 33043979)
    • (2001) European Journal of Pharmacology , vol.429 , Issue.1-3 , pp. 23-37
    • Zimmermann, M.1
  • 12
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: A maladaptive response of the nervous system to damage
    • Costigan, M.; Scholz, J.; Woolf, C. J. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu. Rev. Neurosci., 2009, 32, 1-32.
    • (2009) Annu. Rev. Neurosci. , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 13
    • 70349845440 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pain
    • Basbaum, A. I.; Bautista, D. M.; Scherrer, G.; Julius, D. Cellular and molecular mechanisms of pain. Cell, 2009, 139, 267-284.
    • (2009) Cell , vol.139 , pp. 267-284
    • Basbaum, A.I.1    Bautista, D.M.2    Scherrer, G.3    Julius, D.4
  • 14
    • 73949096000 scopus 로고    scopus 로고
    • Voltage-gated sodium channels: Therapeutic targets for pain
    • Dib-Hajj, S. D.; Black, J. A.; Waxman, S. G. Voltage-gated sodium channels: therapeutic targets for pain. Pain Med., 2009, 10, 1260-1269.
    • (2009) Pain Med. , vol.10 , pp. 1260-1269
    • Dib-Hajj, S.D.1    Black, J.A.2    Waxman, S.G.3
  • 15
    • 45749155596 scopus 로고    scopus 로고
    • Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine
    • DOI 10.1124/jpet.107.133413
    • Sheets, P. L.; Heers, C.; Stoehr, T.; Cummins, T. R. Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine. J. Pharmacol. Exp. Ther., 2008, 326, 89-99. (Pubitemid 351872141)
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.326 , Issue.1 , pp. 89-99
    • Sheets, P.L.1    Heers, C.2    Stoehr, T.3    Cummins, T.R.4
  • 16
    • 33745159996 scopus 로고    scopus 로고
    • The role of T-type calcium channels in epilepsy and pain
    • DOI 10.2174/138161206777585184
    • Nelson, M. T.; Todorovic, S. M.; Perez-Reyes, E. The role of T-type calcium channels in epilepsy and pain. Curr. Pharm. Des., 2006, 12, 2189-2197. (Pubitemid 43891394)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.18 , pp. 2189-2197
    • Nelson, M.T.1    Todorovic, S.M.2    Perez-Reyes, E.3
  • 17
    • 0036844605 scopus 로고    scopus 로고
    • Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy
    • DOI 10.1097/00002508-200211000-00002
    • Schmader, K. E. Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy. Pain, 2002, 350-354. (Pubitemid 35291575)
    • (2002) Clinical Journal of Pain , vol.18 , Issue.6 , pp. 350-354
    • Schmader, K.E.1
  • 18
    • 33646682816 scopus 로고    scopus 로고
    • Epidemiology of refractory neuropathic pain
    • DOI 10.1111/j.1533-2500.2006.00054.x
    • Taylor, R. S. Epidemiology of refractory neuropathic pain. Pain Pract., 2006, 6, 22-26. (Pubitemid 43732685)
    • (2006) Pain Practice , vol.6 , Issue.1 , pp. 22-26
    • Taylor, R.S.1
  • 19
    • 0031053871 scopus 로고    scopus 로고
    • Comparison of three rodent neuropathic pain models
    • DOI 10.1007/BF02450318
    • Kim, K. J.; Yoon, Y. W.; Chung, J. M. Comparison of three rodent neuropathic pain models. Exp. Brain Res., 1997, 113, 200-206. (Pubitemid 27090842)
    • (1997) Experimental Brain Research , vol.113 , Issue.2 , pp. 200-206
    • Kim, K.J.1    Yoon, Y.W.2    Chung, J.M.3
  • 20
    • 46449122432 scopus 로고    scopus 로고
    • Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy
    • DOI 10.1254/jphs.08032FP
    • Tanabe, M.; Murakami, T.; Ono, H. Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy. J. Pharmacol. Sci., 2008, 107, 213-220. (Pubitemid 351931022)
    • (2008) Journal of Pharmacological Sciences , vol.107 , Issue.2 , pp. 213-220
    • Tanabe, M.1    Murakami, T.2    Ono, H.3
  • 21
    • 0025014877 scopus 로고
    • The rat paw formalin test: Comparison of noxious agents
    • DOI 10.1016/0304-3959(90)90073-M
    • Wheeler-Aceto, H.; Porreca, F. The rat paw formalin test: comparison of noxious agents. Pain, 1990, 40, 229-238. (Pubitemid 20070791)
    • (1990) Pain , vol.40 , Issue.2 , pp. 229-238
    • Wheeler-Aceto, H.1    Porreca, F.2    Cowan, A.3
  • 22
    • 0035817449 scopus 로고    scopus 로고
    • 1A receptor-mediated, behaviorally specific analgesia
    • DOI 10.1016/S0014-2999(01)01029-9, PII S0014299901010299
    • Bardin, L. In the formalin model of tonic nociceptive pain, 8-OH-DPAT produces 5-HT1A receptor-mediated, behaviorally specific analgesia. Eur. J. Pharmacol., 2001, 421, 109-114. (Pubitemid 32524081)
    • (2001) European Journal of Pharmacology , vol.421 , Issue.2 , pp. 109-114
    • Bardin, L.1    Tarayre, J.-P.2    Koek, W.3    Colpaert, F.C.4
  • 23
    • 78149357203 scopus 로고    scopus 로고
    • Central mechanisms of pathological pain
    • Kuner, R. Central mechanisms of pathological pain. Nat. Med., 2010, 16, 1258-1266.
    • (2010) Nat. Med. , vol.16 , pp. 1258-1266
    • Kuner, R.1
  • 24
    • 23844508131 scopus 로고    scopus 로고
    • Antiepileptics and the treatment of neuropathic pain: Evidence from animal models
    • DOI 10.2174/1381612054865000
    • Blackburn-Munro, G.; Erichsen, H. K. Antiepileptics and the treatment of neuropathic pain: evidence from animal models. Curr. Pharm. Des., 2005, 11, 2961-2976. (Pubitemid 41149936)
    • (2005) Current Pharmaceutical Design , vol.11 , Issue.23 , pp. 2961-2976
    • Blackburn-Munro, G.1    Erichsen, H.K.2
  • 25
    • 27744565911 scopus 로고    scopus 로고
    • Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain
    • DOI 10.1016/j.neuropharm.2005.06.008, PII S0028390805002224
    • Winkler, I.; Sobol, E.; Yagen, B.; Steinman, A.; Devor, M.; Bialer, M. Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain. Neuropharmacol, . 2005, 49, 1110-1120. (Pubitemid 41608635)
    • (2005) Neuropharmacology , vol.49 , Issue.8 , pp. 1110-1120
    • Winkler, I.1    Sobol, E.2    Yagen, B.3    Steinman, A.4    Devor, M.5    Bialer, M.6
  • 26
    • 74049163222 scopus 로고    scopus 로고
    • Key factors in the discovery and development of new antiepileptic drugs
    • Bialer, M.; White, H. S. Key factors in the discovery and development of new antiepileptic drugs. Nat. Rev. Drug Discov., 2010, 9, 68-82.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 68-82
    • Bialer, M.1    White, H.S.2
  • 27
    • 80052921009 scopus 로고    scopus 로고
    • Diltiazem enhances the protective activity of oxcarbazepine against maximal electroshock-induced seizures in mice
    • Zadrozniak, A.; Trojnar, M.; Trojnar, M. Diltiazem enhances the protective activity of oxcarbazepine against maximal electroshock-induced seizures in mice. J. Pre-Clin. Clin. Res., 2008, 2, 147-152.
    • (2008) J. Pre-Clin. Clin. Res. , vol.2 , pp. 147-152
    • Zadrozniak, A.1    Trojnar, M.2    Trojnar, M.3
  • 29
    • 79958781995 scopus 로고    scopus 로고
    • Dose-dependent risk of malformations with antiepileptic drugs: An analysis of data from the EURAP epilepsy and pregnancy registry
    • Tomson, T.; Battino, D.; Bonizzoni, E.; Craig, J.; Lindhout, D.; Sabers, A.; Perucca, E.; Vajda, F. Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry. Lancet Neurol., 2011, 10, 609-617.
    • (2011) Lancet Neurol. , vol.10 , pp. 609-617
    • Tomson, T.1    Battino, D.2    Bonizzoni, E.3    Craig, J.4    Lindhout, D.5    Sabers, A.6    Perucca, E.7    Vajda, F.8
  • 30
    • 0031921954 scopus 로고    scopus 로고
    • Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats
    • DOI 10.1016/S0304-3959(98)00004-9, PII S0304395998000049
    • Chapman, V.; Suzuki, R.; Chamarette, H. L.; Rygh, L. J.; Dickenson, A. H. Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats. Pain, 1998, 75, 261-272. (Pubitemid 28160137)
    • (1998) Pain , vol.75 , Issue.2-3 , pp. 261-272
    • Chapman, V.1    Suzuki, R.2    Chamarette, H.L.C.3    Rygh, L.J.4    Dickenson, A.H.5
  • 32
    • 0037056091 scopus 로고    scopus 로고
    • Use of anticonvulsants for treatment of neuropathic pain
    • Backonja, M. M. Use of anticonvulsants for treatment of neuropathic pain. Neurology2002, 59, S14-S17.
    • Neurology2002 , vol.59
    • Backonja, M.M.1
  • 33
    • 0037403147 scopus 로고    scopus 로고
    • Rationale and evidence for the use of oxcarbazepine in neuropathic pain
    • DOI 10.1016/S0885-3924(03)00067-8
    • Carrazana, E. Rationale and evidence for the use of oxcarbazepine in neuropathic pain. J. Pain Symptom Manage., 2003, 25, S31-S35. (Pubitemid 36411839)
    • (2003) Journal of Pain and Symptom Management , vol.25 , Issue.5 SUPPL.
    • Carrazana, E.1    Mikoshiba, I.2
  • 35
    • 23944454409 scopus 로고    scopus 로고
    • The suppressive effects of oxcarbazepine on mechanical and cold allodynia in a rat model of neuropathic pain
    • DOI 10.1213/01.ane.0000167283.80463.d7
    • Jang, Y.; Kim, E S.; Park, S. S.; Lee, J.; Moon, D. E. The suppressive effects of oxcarbazepine on mechanical and cold allodynia in a rat model of neuropathic pain. Anesth. Analg. 2005, 101, 800-806. (Pubitemid 41208514)
    • (2005) Anesthesia and Analgesia , vol.101 , Issue.3 , pp. 800-806
    • Jang, Y.1    Kim, E.S.2    Park, S.S.3    Lee, J.4    Moon, D.E.5
  • 36
    • 0022534337 scopus 로고
    • 2) receptors
    • Fujiwara, Y.; Sato, M.; Otsuki, S. Interaction of carbamazepine and other drugs with adenosine (A1 and A2) receptors. Psychopharmacol., 1986, 90, 332-335. (Pubitemid 16022466)
    • (1986) Psychopharmacology , vol.90 , Issue.3 , pp. 332-335
    • Fujiwara, Y.1    Sato, M.2    Otsuki, S.3
  • 38
    • 24044458603 scopus 로고    scopus 로고
    • Oxcarbazepine in painful diabetic neuropathy: A randomized, placebo-controlled study
    • DOI 10.1016/j.ejpain.2004.11.006, PII S1090380104001533
    • Dogra, S.; Beydoun, S.; Mazzola, J.; Hopwood, M.; Wan, Y. Oxcarbazepine in painful diabetic neuropathy: a randomized, placebo-controlled study. Eur. J. Pain, 2005, 9, 543-554. (Pubitemid 41219786)
    • (2005) European Journal of Pain , vol.9 , Issue.5 , pp. 543-554
    • Dogra, S.1    Beydoun, S.2    Mazzola, J.3    Hopwood, M.4    Wan, Y.5
  • 39
    • 33745911608 scopus 로고    scopus 로고
    • Oxcarbazepine in painful diabetic neuropathy: Results of a dose-ranging study
    • DOI 10.1111/j.1600-0404.2006.00631.x
    • Beydoun, A.; Shaibani, A.; Hopwood, M.; Wan, Y. Oxcarbazepine in painful diabetic neuropathy: results of a dose-ranging study. Acta Neurologica Scandinavica2006, 113, 395-404. (Pubitemid 44046325)
    • (2006) Acta Neurologica Scandinavica , vol.113 , Issue.6 , pp. 395-404
    • Beydoun, A.1    Shaibani, A.2    Hopwood, M.3    Wan, Y.4
  • 40
    • 33746866695 scopus 로고    scopus 로고
    • A randomized, placebo-controlled study of oxcarbazepine in painful diabetic neuropathy
    • DOI 10.1111/j.1600-0404.2005.00559.x
    • Grosskopf, J.; Mazzola, J.; Wan, Y.; Hopwood, M. A randomized, placebocontrolled study of oxcarbazepine in painful diabetic neuropathy. Acta Neurol. Scand., 2006, 114, 177-180. (Pubitemid 44185910)
    • (2006) Acta Neurologica Scandinavica , vol.114 , Issue.3 , pp. 177-180
    • Grosskopf, J.1    Mazzola, J.2    Wan, Y.3    Hopwood, M.4
  • 41
    • 78651277431 scopus 로고    scopus 로고
    • Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models
    • Rowley, N. M.; White, H. S. Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models. Epilepsy Res., 2010, 92, 163-169.
    • (2010) Epilepsy Res. , vol.92 , pp. 163-169
    • Rowley, N.M.1    White, H.S.2
  • 42
    • 9144262953 scopus 로고    scopus 로고
    • Effects of 2-[N-(4-Chlorophenyl)-N-methylamino]-4H-pyrido[3.2-e]-1,3- thiazin-4-one (YM928), an Orally Active α-Amino-3-hydroxy-5-methyl-4- isoxazolepropionic Acid Receptor Antagonist, in Models of Generalized Epileptic Seizure in Mice and Rats
    • DOI 10.1124/jpet.103.058495
    • Yamashita, H.; Ohno, K.; Amada, Y.; Hattori, H.; Ozawa-Funatsu, Y.; Toya, T.; Inami, H.; Shishikura, J.; Sakamoto, S.; Okada, M. Effects of 2-[N-(4-Chlorophenyl)-N-methylamino]-4H-pyrido[3. 2-e]-1, 3-thiazin-4-one (YM928), an orally active a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, in models of generalized epileptic seizure in mice and rats. J. Pharmacol. Exp. Ther., 2004, 308, 127-133. (Pubitemid 38090710)
    • (2004) Journal of Pharmacology and Experimental Therapeutics , vol.308 , Issue.1 , pp. 127-133
    • Yamashita, H.1    Ohno, K.2    Amada, Y.3    Hattori, H.4    Ozawa-Funatsu, Y.5    Toya, T.6    Inami, H.7    Shishikura, J.-I.8    Sakamoto, S.9    Okada, M.10    Yamaguchi, T.11
  • 44
    • 78650823193 scopus 로고    scopus 로고
    • Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsy
    • Lee, S. A.; Lee, H. W.; Heo, K.; Shin, D. J.; Song, H. K.; Kim, O. J.; Lee, S. M.; Kim, S. O.; Lee, B. I. Cognitive and behavioral effects of lamotrigine and carbamazepine monotherapy in patients with newly diagnosed or untreated partial epilepsy. Seizure, 2011, 20, 49-54.
    • (2011) Seizure , vol.20 , pp. 49-54
    • Lee, S.A.1    Lee, H.W.2    Heo, K.3    Shin, D.J.4    Song, H.K.5    Kim, O.J.6    Lee, S.M.7    Kim, S.O.8    Lee, B.I.9
  • 47
    • 79957502800 scopus 로고    scopus 로고
    • Lamotrigine for trigeminal neuralgia: Efficacy and safety in comparison with carbamazepine
    • Shaikh, S.; Yaacob, H. B.; Abd Rahman, R. B. Lamotrigine for trigeminal neuralgia: Efficacy and safety in comparison with carbamazepine. J. Chin. Med. Assoc., 2011, 74, 243-249.
    • (2011) J. Chin. Med. Assoc. , vol.74 , pp. 243-249
    • Shaikh, S.1    Yaacob, H.B.2    Abd Rahman, R.B.3
  • 48
    • 0035859943 scopus 로고    scopus 로고
    • Lamotrigine reduces painful diabetic neuropathy: A randomized, controlled study
    • Eisenberg, E.; Lurie, Y.; Braker, C.; Daoud, D.; Ishay, A. Lamotrigine reduces painful diabetic neuropathy: a randomized, controlled study. Neurology, 2001, 57, 505-509. (Pubitemid 32757601)
    • (2001) Neurology , vol.57 , Issue.3 , pp. 505-509
    • Eisenberg, E.1    Lurie, Y.2    Braker, C.3    Daoud, D.4    Ishay, A.5
  • 49
    • 33947411319 scopus 로고    scopus 로고
    • Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy
    • DOI 10.1111/j.1464-5491.2007.02093.x
    • Jose, V. M.; Bhansali, A.; Hota, D.; Pandhi, P. Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy. Diabet. Med., 2007, 24, 377-383. (Pubitemid 46452398)
    • (2007) Diabetic Medicine , vol.24 , Issue.4 , pp. 377-383
    • Jose, V.M.1    Bhansali, A.2    Hota, D.3    Pandhi, P.4
  • 50
    • 46049110377 scopus 로고    scopus 로고
    • Efficacy of lamotrigine in the management of chemotherapy-induced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled trial, N01C3
    • DOI 10.1002/cncr.23482
    • Rao, R. D.; Flynn, P. J.; Sloan, J. A.; Wong, G. Y.; Novotny, P.; Johnson, D. B.; Gross, H. M.; Renno, S. I.; Nashawaty, M.; Loprinzi, C. L. Efficacy of lamotrigine in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled trial, N01C3. Cancer, 2008, 112, 2802-2808. (Pubitemid 351969227)
    • (2008) Cancer , vol.112 , Issue.12 , pp. 2802-2808
    • Rao, R.D.1    Flynn, P.J.2    Sloan, J.A.3    Wong, G.Y.4    Novotny, P.5    Johnson, D.B.6    Gross, H.M.7    Renno, S.I.8    Nashawaty, M.9    Loprinzi, C.L.10
  • 51
    • 0034643845 scopus 로고    scopus 로고
    • A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy
    • Simpson, D. M.; Olney, R.; McArthur, J. C.; Khan, A.; Godbold, J.; Ebel-Frommer, K. A placebo-controlled trial of lamotrigine for painful HIVassociated neuropath . Neurology, 2000, 54, 2115-2119. (Pubitemid 30397212)
    • (2000) Neurology , vol.54 , Issue.11 , pp. 2115-2119
    • Simpson, D.M.1    Olney, R.2    McArthur, J.C.3    Khan, A.4    Godbold, J.5    Ebel-Frommer, K.6
  • 52
    • 37349071555 scopus 로고    scopus 로고
    • The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels
    • DOI 10.1124/mol.107.039867
    • Errington, A. C.; Sto, T.; Heers, C.; Lees, G. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Mol. Pharmacol., 2008, 73, 157-169. (Pubitemid 350294207)
    • (2008) Molecular Pharmacology , vol.73 , Issue.1 , pp. 157-169
    • Errington, A.C.1    Stohr, T.2    Heers, C.3    Lees, G.4
  • 54
    • 79952449282 scopus 로고    scopus 로고
    • Successful treatment of refractory simple motor status epilepticus with lacosamide and levetiracetam
    • Chen, L. L. K.; Haneef, Z.; Dorsch, A.; Keselman, I.; Stern, J. M. Successful treatment of refractory simple motor status epilepticus with lacosamide and levetiracetam. Seizure, 2011, 20, 263-265.
    • (2011) Seizure , vol.20 , pp. 263-265
    • Chen, L.L.K.1    Haneef, Z.2    Dorsch, A.3    Keselman, I.4    Stern, J.M.5
  • 55
    • 78650783166 scopus 로고    scopus 로고
    • Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus
    • Koubeissi, M. Z.; Mayor, C. L.; Estephan, B.; Rashid, S.; Azar, N. J. Efficacy and safety of intravenous lacosamide in refractory nonconvulsive status epilepticus. Acta Neurol. Scand., 2011, 123, 142-146.
    • (2011) Acta Neurol. Scand. , vol.123 , pp. 142-146
    • Koubeissi, M.Z.1    Mayor, C.L.2    Estephan, B.3    Rashid, S.4    Azar, N.J.5
  • 56
    • 33646911126 scopus 로고    scopus 로고
    • Seeking a mechanism of action for the novel anticonvulsant lacosamide
    • DOI 10.1016/j.neuropharm.2006.02.002, PII S0028390806000293
    • Errington, A. C.; Coyne, L.; Stöhr, T.; Selve, N.; Lees, G. Seeking a mechanism of action for the novel anticonvulsant lacosamide. Neuropharmacol., 2006, 50, 1016-1029. (Pubitemid 43794912)
    • (2006) Neuropharmacology , vol.50 , Issue.8 , pp. 1016-1029
    • Errington, A.C.1    Coyne, L.2    Stohr, T.3    Selve, N.4    Lees, G.5
  • 57
    • 34249035783 scopus 로고    scopus 로고
    • Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain
    • DOI 10.1016/j.ejphar.2007.02.041, PII S0014299907002828
    • Beyreuther, B. K.; Callizot, N.; Brot, M. D.; Feldman, R.; Bain, S. C.; Stöhr, T. Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain. Eur. J. Pharmacol., 2007, 565, 98-104. (Pubitemid 46782774)
    • (2007) European Journal of Pharmacology , vol.565 , Issue.1-3 , pp. 98-104
    • Beyreuther, B.K.1    Callizot, N.2    Brot, M.D.3    Feldman, R.4    Bain, S.C.5    Stohr, T.6
  • 58
    • 68749094130 scopus 로고    scopus 로고
    • Effects of lacosamide, a novel sodium channel modulator, on dorsal horn neuronal responses in a rat model of neuropathy
    • Bee, L. A.; Dickenson, A. H. Effects of lacosamide, a novel sodium channel modulator, on dorsal horn neuronal responses in a rat model of neuropathy. Neuropharmacol., 2009, 57, 472-479.
    • (2009) Neuropharmacol. , vol.57 , pp. 472-479
    • Bee, L.A.1    Dickenson, A.H.2
  • 59
    • 33751170209 scopus 로고    scopus 로고
    • Lacosamide, a new anti-epileptic, alleviates neuropathic pain-like behaviors in rat models of spinal cord or trigeminal nerve injury
    • DOI 10.1016/j.ejphar.2006.09.040, PII S0014299906010673
    • Hao, J. X.; Stöhr, T.; Selve, N.; Wiesenfeld-Hallin, Z.; Xu, X. J. Lacosamide, a new anti-epileptic, alleviates neuropathic pain-like behaviors in rat models of spinal cord or trigeminal nerve injury. Eur. J. Pharmacol., 2006, 553, 135-140. (Pubitemid 44779609)
    • (2006) European Journal of Pharmacology , vol.553 , Issue.1-3 , pp. 135-140
    • Hao, J.-X.1    Stohr, T.2    Selve, N.3    Wiesenfeld-Hallin, Z.4    Xu, X.-J.5
  • 60
    • 33646882590 scopus 로고    scopus 로고
    • Antinociceptive efficacy of lacosamide in a rat model for painful diabetic neuropathy
    • DOI 10.1016/j.ejphar.2006.04.009, PII S0014299906004055
    • Beyreuther, B.; Callizot, N.; Stöhr, T. Antinociceptive efficacy of lacosamide in a rat model for painful diabetic neuropathy. Eur. J. Pharmacol., 2006, 539, 64-70. (Pubitemid 43783512)
    • (2006) European Journal of Pharmacology , vol.539 , Issue.1-2 , pp. 64-70
    • Beyreuther, B.1    Callizot, N.2    Stohr, T.3
  • 61
    • 32844470254 scopus 로고    scopus 로고
    • Lacosamide displays potent antinociceptive effects in animal models for inflammatory pain
    • DOI 10.1016/j.ejpain.2005.04.002, PII S109038010500056X
    • Stöhr, T.; Krause, E.; Selve, N. Lacosamide displays potent antinociceptive effects in animal models for inflammatory pain. Eur. J. Pain, 2006, 10, 241-249. (Pubitemid 43255211)
    • (2006) European Journal of Pain , vol.10 , Issue.3 , pp. 241-249
    • Stohr, T.1    Krause, E.2    Selve, N.3
  • 62
    • 67650809082 scopus 로고    scopus 로고
    • Lacosamide in painful diabetic neuropathy: An 18-week doubleblind placebo-controlled trial
    • Shaibani, A.; Fares, S.; Selam, J. L.; Arslanian, A.; Simpson, J.; Sen, D.; Bongardt, S. Lacosamide in painful diabetic neuropathy: an 18-week doubleblind placebo-controlled trial. J. Pain, 2009, 10, 818-828.
    • (2009) J. Pain , vol.10 , pp. 818-828
    • Shaibani, A.1    Fares, S.2    Selam, J.L.3    Arslanian, A.4    Simpson, J.5    Sen, D.6    Bongardt, S.7
  • 63
    • 33846535387 scopus 로고    scopus 로고
    • Lacosamide in painful diabetic peripheral neuropathy: A phase 2 double-blind placebo-controlled study
    • DOI 10.1097/01.ajp.0000210957.39621.b2, PII 0000250820070200000006
    • Rauck, R. L.; Shaibani, A.; Biton, V.; Simpson, J.; Koch, B. Lacosamide in painful diabetic peripheral neuropathy: a phase 2 double-blind placebocontrolled study. Clin. J. Pain, 2007, 23, 150-158. (Pubitemid 46150939)
    • (2007) Clinical Journal of Pain , vol.23 , Issue.2 , pp. 150-158
    • Rauck, R.L.1    Shaibani, A.2    Biton, V.3    Simpson, J.4    Koch, B.5
  • 66
    • 32644473010 scopus 로고    scopus 로고
    • Introduction to zonisamide
    • DOI 10.1016/j.eplepsyres.2005.11.004, PII S0920121105002962, New Options for Epilepsy - Focus on Zonisamide
    • Baulac, M. Introduction to zonisamide. Epilepsy Res., 2006, 68, S3-S9. (Pubitemid 43247591)
    • (2006) Epilepsy Research , vol.68 , Issue.SUPPL. 2
    • Baulac, M.1
  • 67
    • 15744384103 scopus 로고    scopus 로고
    • Oxcarbazepine, topiramate, zonisamide, and levetiracetam: Potential use in neuropathic pain
    • DOI 10.1016/S1543-5946(03)80013-2
    • Guay, D. Oxcarbazepine, topiramate, zonisamide, and levetiracetam: Potential use in neuropathic pain. Am. J. Geriatr. Pharmacother., 2003, 1, 18-37. (Pubitemid 40410984)
    • (2003) American Journal Geriatric Pharmacotherapy , vol.1 , Issue.1 , pp. 18-37
    • Guay, D.R.P.1
  • 68
    • 1442344104 scopus 로고    scopus 로고
    • 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E., Eds., Lippincott Williams & Wilkins Healthcare: Philadelphia
    • Macdonald, R. In: Antiepileptic Drugs, 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E., Eds.; Lippincott Williams & Wilkins Healthcare: Philadelphia, 2002; pp. 867-872.
    • (2002) Antiepileptic Drugs , pp. 867-872
    • MacDonald, R.1
  • 69
    • 7044224816 scopus 로고    scopus 로고
    • Review of United States and European clinical trials of zonisamide in the treatment of refractory partial-onset seizures
    • Faught, E. Review of United States and European clinical trials of zonisamide in the treatment of refractory partial-onset seizures. Seizure, 13 Suppl 1, S59-S65.
    • Seizure , vol.13 , Issue.SUPPL. 1
    • Faught, E.1
  • 70
    • 0038024328 scopus 로고    scopus 로고
    • The effect of systemic zonisamide (Zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy
    • Hord, A. H.; Denson, D. D.; Chalfoun, A. G.; Azevedo, M. I. The effect of systemic zonisamide (zonegran) on thermal hyperalgesia and mechanical allodynia in rats with an experimental mononeuropathy. Anesth. Analg., 2003, 1700-1706. (Pubitemid 36623130)
    • (2003) Anesthesia and Analgesia , vol.96 , Issue.6 , pp. 1700-1706
    • Hord, A.H.1    Denson, D.D.2    Chalfoun, A.G.3    Azevedo, M.I.4
  • 71
    • 0031126348 scopus 로고    scopus 로고
    • A pharmacological and clinical review on Topiramate, a new antiepileptic drug
    • DOI 10.1006/phrs.1997.0124
    • Perucca, E. A pharmacological and clinical review on topiramate, a new antiepileptic drug. Pharmacol. Res., 1997, 35, 241-256. (Pubitemid 27331181)
    • (1997) Pharmacological Research , vol.35 , Issue.4 , pp. 241-256
    • Perucca, E.1
  • 72
    • 1942436861 scopus 로고    scopus 로고
    • Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist
    • DOI 10.1016/j.neuropharm.2004.02.010, PII S0028390804000486
    • Kaminski, R. M.; Banerjee, M.; Rogawski, M. A. Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist. Neuropharmacol., 2004, 46, 1097-1104. (Pubitemid 38529933)
    • (2004) Neuropharmacology , vol.46 , Issue.8 , pp. 1097-1104
    • Kaminski, R.M.1    Banerjee, M.2    Rogawski, M.A.3
  • 73
    • 2442640189 scopus 로고    scopus 로고
    • Evaluation of topiramate as an anti-hyperalgesic and neuroprotective agent in the peripheral nervous system
    • DOI 10.1111/j.1085-9489.2004.009205.x
    • Bischofs, S.; Zelenka, M.; Sommer, C. Evaluation of topiramate as an antihyperalgesic and neuroprotective agent in the peripheral nervous system. J. Periph. Nerv. Syst., 2004, 9, 70-78. (Pubitemid 38669199)
    • (2004) Journal of the Peripheral Nervous System , vol.9 , Issue.2 , pp. 70-78
    • Bischofs, S.1    Zelenka, M.2    Sommer, C.3
  • 74
    • 0035029683 scopus 로고    scopus 로고
    • Topiramate: A review of its use in childhood epilepsy
    • Ormrod, D.; McClellan, K. Topiramate: a review of its use in childhood epilepsy. Paediatr. Drugs, 2001, 3, 293-319. (Pubitemid 32391810)
    • (2001) Paediatric Drugs , vol.3 , Issue.4 , pp. 293-319
    • Ormrod, D.1    McClellan, K.2
  • 75
    • 33845197528 scopus 로고    scopus 로고
    • Effects of topiramate on the chronic constriction injury model in the rat
    • DOI 10.1016/j.jpain.2006.04.008, PII S1526590006007668
    • Benoliel, R.; Tal, M.; Eliav, E. Effects of topiramate on the chronic constriction injury model in the rat. J. Pain, 2006, 7, 878-883. (Pubitemid 44854736)
    • (2006) Journal of Pain , vol.7 , Issue.12 , pp. 878-883
    • Benoliel, R.1    Tal, M.2    Eliav, E.3
  • 76
    • 4644369311 scopus 로고    scopus 로고
    • Topiramate vs placebo in painful diabetic neuropathy: Analgesic and metabolic effects
    • Raskin, P.; Donofrio, P. D.; Rosenthal, N. R.; Hewitt, D. J.; Jordan, D. M.; Xiang, J.; Vinik, A. I. Topiramate vs placebo in painful diabetic neuropathy: analgesic and metabolic effects. Neurology, 2004, 63, 865-873. (Pubitemid 39297649)
    • (2004) Neurology , vol.63 , Issue.5 , pp. 865-873
    • Raskin, P.1    Donofrio, P.D.2    Rosenthal, N.R.3    Hewitt, D.J.4    Jordan, D.M.5    Xiang, J.6    Vinik, A.I.7
  • 77
    • 4644302209 scopus 로고    scopus 로고
    • Topiramate in painful diabetic polyneuropathy: Findings from three double-blind placebo-controlled trials
    • DOI 10.1111/j.1600-0404.2004.00338.x
    • Thienel, U.; Neto, W.; Schwabe, S. K.; Vijapurkar, U. Topiramate in painful diabetic polyneuropathy: findings from three double-blind placebo-controlled trials. Acta Neurol. Scand., 2004, 110, 221-231. (Pubitemid 39274056)
    • (2004) Acta Neurologica Scandinavica , vol.110 , Issue.4 , pp. 221-231
    • Thienel, U.1    Neto, W.2    Schwabe, S.K.3    Vijapurkar, U.4
  • 80
    • 66249120340 scopus 로고    scopus 로고
    • A mouse model of sural nerve injury-induced neuropathy: Gabapentin inhibits pain-related behaviors and the hyperactivity of wide-dynamic range neurons in the dorsal horn
    • Omori, Y.; Kagaya, K.; Enomoto, R.; Sasaki, A.; Andoh, T.; Nojima, H.; Takahata, H.; Kuraishi, Y. A mouse model of sural nerve injury-induced neuropathy: gabapentin inhibits pain-related behaviors and the hyperactivity of wide-dynamic range neurons in the dorsal horn. J. Pharmacol. Sci., 2009, 109, 532-539.
    • (2009) J. Pharmacol. Sci. , vol.109 , pp. 532-539
    • Omori, Y.1    Kagaya, K.2    Enomoto, R.3    Sasaki, A.4    Andoh, T.5    Nojima, H.6    Takahata, H.7    Kuraishi, Y.8
  • 81
    • 78650178478 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of the Tenth Eilat Conference (EILAT X)
    • Bialer, M.; Johannessen, S. I.; Levy, R. H.; Perucca, E.; Tomson, T.; White, H. S. Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X). Epilepsy Res., 2010, 92, 89-124.
    • (2010) Epilepsy Res. , vol.92 , pp. 89-124
    • Bialer, M.1    Johannessen, S.I.2    Levy, R.H.3    Perucca, E.4    Tomson, T.5    White, H.S.6
  • 82
    • 0038144920 scopus 로고    scopus 로고
    • 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E., Eds., Lippincott Williams & Wilkins: Philadelphia
    • Taylor, C. P. In Antiepileptic Drugs, 5th ed.; Levy, R. H.; Mattson, R. H.; Meldrum, B. S.; Perucca, E., Eds.; Lippincott Williams & Wilkins: Philadelphia, 2002; pp. 321-334.
    • (2002) Antiepileptic Drugs , pp. 321-334
    • Taylor, C.P.1
  • 84
    • 0026095572 scopus 로고
    • Double-blind study of gabapentin in the treatment of partial seizures
    • Sivenius, J.; Kälviäinen, R.; Ylinen, A.; Riekkinen, P. Double-blind study of gabapentin in the treatment of partial seizures. Epilepsia, 1991, 32, 539-542.
    • (1991) Epilepsia , vol.32 , pp. 539-542
    • Sivenius, J.1    Kälviäinen, R.2    Ylinen, A.3    Riekkinen, P.4
  • 85
    • 0032800766 scopus 로고    scopus 로고
    • Gabapentin as add-on therapy in children with refractory partial seizures: A 12-week, multicentre, double-blind, placebo-controlled study
    • DOI 10.1111/j.1528-1157.1999.tb00833.x
    • Appleton, R.; Fichtner, K.; LaMoreaux, L.; Alexander, J.; Halsall, G.; Murray, G.; Garofalo, E. Gabapentin as add-on therapy in children with refractory partial seizures: a 12-week, multicentre, double-blind, placebocontrolled study. Epilepsia, 1999, 40, 1147-1154. (Pubitemid 29372632)
    • (1999) Epilepsia , vol.40 , Issue.8 , pp. 1147-1154
    • Appleton, R.1    Fichtner, K.2    LaMoreaux, L.3    Alexander, J.4    Halsall, G.5    Murray, G.6    Garofalo, E.7
  • 86
    • 0029803259 scopus 로고    scopus 로고
    • Gabapentin in naive childhood absence epilepsy: Results from two double- blind, placebo-controlled, multicenter studies
    • Trudeau, V.; Myers, S.; LaMoreaux, L.; Anhut, H.; Garofalo, E.; Ebersole, J. Gabapentin in naive childhood absence epilepsy: results from two doubleblind, placebo-controlled, multicenter studies. J. Child. Neurol., 1996, 11, 470-475. (Pubitemid 26412201)
    • (1996) Journal of Child Neurology , vol.11 , Issue.6 , pp. 470-475
    • Trudeau, V.1    Myers, S.2    LaMoreaux, L.3    Anhut, H.4    Garofalo, E.5    Ebersole, J.6
  • 87
    • 58149316578 scopus 로고    scopus 로고
    • Gabapentin acts within the locus coeruleus to alleviate neuropathic pain
    • Hayashida, K. I.; Obata, H.; Nakajima, K.; Eisenach, J. C. Gabapentin acts within the locus coeruleus to alleviate neuropathic pain. Anesthesiology, 2008, 109, 1077-1084.
    • (2008) Anesthesiology , vol.109 , pp. 1077-1084
    • Hayashida, K.I.1    Obata, H.2    Nakajima, K.3    Eisenach, J.C.4
  • 88
    • 77952884895 scopus 로고    scopus 로고
    • Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid
    • Kaufmann, D.; Yagen, B.; Minert, A.; Wlodarczyk, B.; Finnell, R. H.; Schurig, V.; Devor, M.; Bialer, M. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacol., 2010, 58, 1228-1236.
    • (2010) Neuropharmacol. , vol.58 , pp. 1228-1236
    • Kaufmann, D.1    Yagen, B.2    Minert, A.3    Wlodarczyk, B.4    Finnell, R.H.5    Schurig, V.6    Devor, M.7    Bialer, M.8
  • 90
    • 0033965974 scopus 로고    scopus 로고
    • +-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin
    • DOI 10.1016/S0304-3940(00)00769-2, PII S0304394000007692
    • Dooley, D. J.; Mieske, C. A.; Borosky, S. A. Inhibition of K(+)-evoked glutamate release from rat neocortical and hippocampal slices by gabapentin. Neurosci. Lett., 2000, 280, 107-110. (Pubitemid 30109144)
    • (2000) Neuroscience Letters , vol.280 , Issue.2 , pp. 107-110
    • Dooley, D.J.1    Mieske, C.A.2    Borosky, S.A.3
  • 92
    • 0034750718 scopus 로고    scopus 로고
    • Gabapentin in postherpetic neuralgia: A randomised, double blind, placebo controlled study
    • DOI 10.1016/S0304-3959(01)00407-9, PII S0304395901004079
    • Rice, A. S. C.; Maton, S. Gabapentin in postherpetic neuralgia: a randomised , double blind, placebo controlled study. Pain, 2001, 94, 215-224. (Pubitemid 33016615)
    • (2001) Pain , vol.94 , Issue.2 , pp. 215-224
    • Rice, A.S.C.1    Maton, S.2
  • 93
    • 0037274135 scopus 로고    scopus 로고
    • Gabapentin dosing for neuropathic pain: Evidence from randomized, placebo-controlled clinical trials
    • DOI 10.1016/S0149-2918(03)90011-7
    • Backonja, M.; Glanzman, R. L. Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials. Clin. Ther., 2003, 25, 81-104. (Pubitemid 36206739)
    • (2003) Clinical Therapeutics , vol.25 , Issue.1 , pp. 81-104
    • Backonja, M.1    Glanzman, R.L.2
  • 95
    • 67649185241 scopus 로고    scopus 로고
    • Efficacy and tolerability of gastric-retentive gabapentin for the treatment of postherpetic neuralgia
    • Irving, G.; Jensen, M.; Cramer, M.; Wu, J.; Chiang, Y. K.; Tark, M.; Wallace, M. Efficacy and tolerability of gastric-retentive gabapentin for the treatment of postherpetic neuralgia. Clin. J. Pain, 2009, 25, 185-192.
    • (2009) Clin. J. Pain , vol.25 , pp. 185-192
    • Irving, G.1    Jensen, M.2    Cramer, M.3    Wu, J.4    Chiang, Y.K.5    Tark, M.6    Wallace, M.7
  • 97
    • 29444449131 scopus 로고    scopus 로고
    • Gabapentin is effective in the treatment of cancer-related neuropathic pain: A prospective, open-label study
    • DOI 10.1089/jpm.2005.8.1118
    • Ross, J. R.; Goller, K.; Hardy, J.; Riley, J.; Broadley, K.; A'Hern, R.; Williams, J. Gabapentin is effective in the treatment of cancer-related neuropathic pain: a prospective, open-label study. J. Palliat. Med., 2005, 8, 1118-1126. (Pubitemid 43010543)
    • (2005) Journal of Palliative Medicine , vol.8 , Issue.6 , pp. 1118-1126
    • Ross, J.R.1    Goller, K.2    Hardy, J.3    Riley, J.4    Broadley, K.5    A'Hern, R.6    Williams, J.7
  • 98
    • 64349124076 scopus 로고    scopus 로고
    • Gabapentin extended release for the treatment of painful diabetic peripheral neuropathy: Efficacy and tolerability in a double-blind, randomized, controlled clinical trial
    • Sandercock, D.; Cramer, M.; Wu, J.; Chiang, Y. K.; Biton, V.; Heritier, M. Gabapentin extended release for the treatment of painful diabetic peripheral neuropathy: efficacy and tolerability in a double-blind, randomized, controlled clinical trial. Diabetes Care2009, 32, e20.
    • (2009) Diabetes Care , vol.32
    • Sandercock, D.1    Cramer, M.2    Wu, J.3    Chiang, Y.K.4    Biton, V.5    Heritier, M.6
  • 99
    • 0030668611 scopus 로고    scopus 로고
    • The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cells
    • Rundfeldt, C. The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cells. Eur. J. Pharmacol., 1997, 336, 24324-24329.
    • (1997) Eur. J. Pharmacol. , vol.336 , pp. 24324-24329
    • Rundfeldt, C.1
  • 100
    • 0034677733 scopus 로고    scopus 로고
    • The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits
    • DOI 10.1016/S0304-3940(00)00866-1, PII S0304394000008661
    • Rundfeldt, C.; Netzer, R. The novel anticonvulsant retigabine activates Mcurrents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits. Neurosci. Lett. 2000, 282, 73-76. (Pubitemid 30129172)
    • (2000) Neuroscience Letters , vol.282 , Issue.1-2 , pp. 73-76
    • Rundfeldt, C.1    Netzer, R.2
  • 101
    • 0033061573 scopus 로고    scopus 로고
    • Progress report on new antiepileptic drugs: A summary of The Fourth Eilat Conference (EILAT IV)
    • DOI 10.1016/S0920-1211(98)00108-9, PII S0920121198001089
    • Bialer, M.; Johannessen, S. I.; Kupferberg, H. J.; Levy, R. H.; Loiseau, P.; Perucca, E. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference (EILAT IV). Epilepsy Res., 1999, 34, 1-41. (Pubitemid 29130316)
    • (1999) Epilepsy Research , vol.34 , Issue.1 , pp. 1-41
    • Bialer, M.1    Johannessen, S.I.2    Kupferberg, H.J.3    Levy, R.H.4    Loiseau, P.5    Perucca, E.6
  • 103
  • 104
    • 79955805815 scopus 로고    scopus 로고
    • Ezogabine: A novel antiepileptic as adjunctive therapy for partial onset seizures
    • Owen, R. T. Ezogabine: a novel antiepileptic as adjunctive therapy for partial onset seizures. Drugs Today, 2010, 46, 815-822.
    • (2010) Drugs Today , vol.46 , pp. 815-822
    • Owen, R.T.1
  • 105
    • 34848923432 scopus 로고    scopus 로고
    • Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety
    • DOI 10.1016/j.neuropharm.2007.07.002, PII S0028390807002110
    • Munro, G.; Erichsen, H. K.; Mirza, N. R. Pharmacological comparison of anticonvulsant drugs in animal models of persistent pain and anxiety. Neuropharmacol., 2007, 53, 609-618. (Pubitemid 47513167)
    • (2007) Neuropharmacology , vol.53 , Issue.5 , pp. 609-618
    • Munro, G.1    Erichsen, H.K.2    Mirza, N.R.3
  • 106
    • 0037462422 scopus 로고    scopus 로고
    • The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain
    • DOI 10.1016/S0014-2999(02)02924-2
    • Blackburn-Munro, G. The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain. Eur. J. Pharmacol., 2003, 460, 109-116. (Pubitemid 36139977)
    • (2003) European Journal of Pharmacology , vol.460 , Issue.2-3 , pp. 109-116
    • Blackburn-Munro, G.1    Jensen, B.S.2
  • 107
    • 79953700565 scopus 로고    scopus 로고
    • The adverse event profile of pregabalin: A systematic review and meta-analysis of randomized controlled trials
    • Zaccara, G.; Gangemi, P.; Perucca, P.; Specchio, L. The adverse event profile of pregabalin: A systematic review and meta-analysis of randomized controlled trials. Epilepsia, 2011, 52, 826-836.
    • (2011) Epilepsia , vol.52 , pp. 826-836
    • Zaccara, G.1    Gangemi, P.2    Perucca, P.3    Specchio, L.4
  • 109
    • 80051669441 scopus 로고    scopus 로고
    • Treatment options in juvenile myoclonic epilepsy
    • Mantoan, L.; Walker, M. Treatment options in juvenile myoclonic epilepsy. Curr. Treat. Options Neurol., 2011, 13, 1-16.
    • (2011) Curr. Treat. Options Neurol. , vol.13 , pp. 1-16
    • Mantoan, L.1    Walker, M.2
  • 110
    • 0032836174 scopus 로고    scopus 로고
    • Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: Are they signalled by distinct primary sensory neurones?
    • DOI 10.1016/S0304-3959(99)00111-6, PII S0304395999001116
    • Field, M. J.; Bramwell, S.; Hughes, J.; Singh, L. Detection of static and dynamic components of mechanical allodynia in rat models of neuropathic pain: are they signalled by distinct primary sensory neurones? Pain, 1999, 83, 303-311. (Pubitemid 29479290)
    • (1999) Pain , vol.83 , Issue.2 , pp. 303-311
    • Field, M.J.1    Bramwell, S.2    Hughes, J.3    Singh, L.4
  • 111
    • 3843088696 scopus 로고    scopus 로고
    • Pregabalin for the treatment of painful diabetic peripheral neuropathy: A double-blind, placebo-controlled trial
    • DOI 10.1016/j.pain.2004.05.001, PII S0304395904002465
    • Rosenstock, J.; Tuchman, M.; Lamoreaux, L.; Sharma, U. Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind , placebocontrolled trial. Pain, 2004, 110, 628-638. (Pubitemid 39036794)
    • (2004) Pain , vol.110 , Issue.3 , pp. 628-638
    • Rosenstock, J.1    Tuchman, M.2    Lamoreaux, L.3    Sharma, U.4
  • 112
    • 33645732694 scopus 로고    scopus 로고
    • Efficacy and tolerability of twice-daily pregabalin for treating pain and related sleep interference in postherpetic neuralgia: A 13-week, randomized trial
    • DOI 10.1185/030079906X80404
    • van Seventer, R.; Feister, H. A.; Young, J. P. J.; Stroker, M.; Versavel, M.; Rigaudy, L. Efficacy and tolerability of twice-daily pregabalin for treating pain and related sleep interference in postherpetic neuralgia: a 13-week, randomized trial. Curr. Med. Res. Opin., 2006, 22, 375-384. (Pubitemid 44296762)
    • (2006) Current Medical Research and Opinion , vol.22 , Issue.2 , pp. 375-384
    • Van Seventer, R.1    Feister, H.A.2    Young Jr., J.P.3    Stoker, M.4    Versavel, M.5    Rigaudy, L.6
  • 113
    • 78650236611 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin for treating neuropathic pain associated with diabetic peripheral neuropathy: A 14 week, randomized, doubleblind, placebo-controlled trial
    • Satoh, J.; Yagihashi, S.; Baba, M.; Suzuki, M.; Arakawa, A.; Yoshiyama, T.; Shoji, S. Efficacy and safety of pregabalin for treating neuropathic pain associated with diabetic peripheral neuropathy: a 14 week, randomized, doubleblind, placebo-controlled trial. Diabet. Med., 2011, 28, 109-116.
    • (2011) Diabet. Med. , vol.28 , pp. 109-116
    • Satoh, J.1    Yagihashi, S.2    Baba, M.3    Suzuki, M.4    Arakawa, A.5    Yoshiyama, T.6    Shoji, S.7
  • 114
    • 36549031246 scopus 로고    scopus 로고
    • Pregabalin for relief of neuropathic pain associated with diabetic neuropathy: A randomized, double-blind study
    • DOI 10.1016/j.ejpain.2007.05.003, PII S1090380107005800
    • Tölle, T.; Freynhagen, R.; Versavel, M.; Trostmann, U.; Young, J. P. Pregabalin for relief of neuropathic pain associated with diabetic neuropathy: a randomized, double-blind study. Eur. J. Pain, 2008, 12, 203-213. (Pubitemid 350180540)
    • (2008) European Journal of Pain , vol.12 , Issue.2 , pp. 203-213
    • Tolle, T.1    Freynhagen, R.2    Versavel, M.3    Trostmann, U.4    Young Jr., J.P.5
  • 115
    • 53949084617 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: A double-blind placebo-controlled trial
    • Arezzo, J. C.; Rosenstock, J.; Lamoreaux, L.; Pauer, L. Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: a double-blind placebo-controlled trial. BMC Neurology, 2008, 8, 33-46.
    • (2008) BMC Neurology , vol.8 , pp. 33-46
    • Arezzo, J.C.1    Rosenstock, J.2    Lamoreaux, L.3    Pauer, L.4
  • 116
    • 79951842505 scopus 로고    scopus 로고
    • Efficacy and tolerability of pregabalin using a flexible, optimized dose schedule in Korean patients with peripheral neuropathic pain: A 10-week, randomized, double-blind, placebocontrolled, multicenter study
    • Moon, D. E.; Lee, D. I.; Lee, S. C.; Song, S. O.; Yoon, D. M.; Yoon, M. H.; Kim, H. K.; Lee, Y. W.; Kim, C.; Lee, P. B. Efficacy and tolerability of pregabalin using a flexible, optimized dose schedule in Korean patients with peripheral neuropathic pain: a 10-week, randomized, double-blind, placebocontrolled, multicenter study. Clin. Ther., 2010, 32, 2370-2385.
    • (2010) Clin. Ther. , vol.32 , pp. 2370-2385
    • Moon, D.E.1    Lee, D.I.2    Lee, S.C.3    Song, S.O.4    Yoon, D.M.5    Yoon, M.H.6    Kim, H.K.7    Lee, Y.W.8    Kim, C.9    Lee, P.B.10
  • 117
    • 79954472100 scopus 로고    scopus 로고
    • Efficacy of pregabalin for peripheral neuropathic pain: Results of an 8-week, flexibledose, double-blind, placebo-controlled study conducted in China
    • Guan, Y.; Ding, X.; Cheng, Y.; Fan, D.; Tan, L.; Wang, Y.; Zhao, Z.; Hong, Z.; Zhou, D.; Pan, X.; Chen, S.; Martin, A.; Tang, H.; Cui, L. Efficacy of pregabalin for peripheral neuropathic pain: results of an 8-week, flexibledose, double-blind, placebo-controlled study conducted in China. Clin. Ther., 2011, 33, 159-166.
    • (2011) Clin. Ther. , vol.33 , pp. 159-166
    • Guan, Y.1    Ding, X.2    Cheng, Y.3    Fan, D.4    Tan, L.5    Wang, Y.6    Zhao, Z.7    Hong, Z.8    Zhou, D.9    Pan, X.10    Chen, S.11    Martin, A.12    Tang, H.13    Cui, L.14
  • 118
    • 78049385777 scopus 로고    scopus 로고
    • Evaluation of the safety and efficacy of pregabalin in older patients with neuropathic pain: Results from a pooled analysis of 11 clinical studies
    • Semel, D.; Murphy, T. K.; Zlateva, G.; Cheung, R.; Emir, B. Evaluation of the safety and efficacy of pregabalin in older patients with neuropathic pain: results from a pooled analysis of 11 clinical studies. BMC Fam. Pract., 2010, 11, 85-97.
    • (2010) BMC Fam. Pract. , vol.11 , pp. 85-97
    • Semel, D.1    Murphy, T.K.2    Zlateva, G.3    Cheung, R.4    Emir, B.5
  • 119
    • 0034257051 scopus 로고    scopus 로고
    • Mechanisms of action of valproate: A commentatory
    • DOI 10.1016/S0197-0186(00)00013-9, PII S0197018600000139
    • Johannessen, C. U. Mechanisms of action of valproate: a commentatory. Neurochem. Int., 2000, 37, 103-110. (Pubitemid 30254142)
    • (2000) Neurochemistry International , vol.37 , Issue.2-3 , pp. 103-110
    • Johannessen, C.U.1
  • 120
    • 0036402177 scopus 로고    scopus 로고
    • Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy
    • Löscher, W. Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy. CNS Drug, s2002, 16, 669-694. (Pubitemid 35176853)
    • (2002) CNS Drugs , vol.16 , Issue.10 , pp. 669-694
    • Loscher, W.1
  • 121
    • 37049031057 scopus 로고    scopus 로고
    • Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid
    • DOI 10.1021/jm7009233
    • Shimshoni, J. A.; Bialer, M.; Wlodarczyk, B.; Finnell, R. H.; Yagen, B. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J. Med. Chem., 2007, 50, 6419-6427. (Pubitemid 350250429)
    • (2007) Journal of Medicinal Chemistry , vol.50 , Issue.25 , pp. 6419-6427
    • Shimshoni, J.A.1    Bialer, M.2    Wlodarczyk, B.3    Finnell, R.H.4    Yagen, B.5
  • 123
    • 0036838156 scopus 로고    scopus 로고
    • Sodium valproate in the management of painful neuropathy in type 2 diabetes - A randomized placebo controlled study
    • DOI 10.1034/j.1600-0404.2002.01229.x
    • Kochar, D. K.; Jain, N.; Agarwal, R. P.; Srivastava, T.; Agarwal, P.; Gupta, S. Sodium valproate in the management of painful neuropathy in type 2 diabetes - a randomized placebo controlled study. Acta Neurol. Scand., 2002, 106, 248-252. (Pubitemid 35177990)
    • (2002) Acta Neurologica Scandinavica , vol.106 , Issue.5 , pp. 248-252
    • Kochar, D.K.1    Jain, N.2    Agarwal, R.P.3    Srivastava, T.4    Agarwal, P.5    Gupta, S.6
  • 124
    • 0842325640 scopus 로고    scopus 로고
    • Valproic acid has no effect on pain in polyneuropathy: A randomized, controlled trial
    • Otto, M.; Bach, F. W.; Jensen, T. S.; Sindrup, S. H. Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trial. Neurology, 2004, 62, 285-288. (Pubitemid 38167141)
    • (2004) Neurology , vol.62 , Issue.2 , pp. 285-288
    • Otto, M.1    Bach, F.W.2    Jensen, T.S.3    Sindrup, S.H.4
  • 125
    • 30544438144 scopus 로고    scopus 로고
    • Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain
    • DOI 10.1038/sj.bjp.0706310
    • Winkler, I.; Blotnik, S.; Shimshoni, J.; Yagen, B.; Devor, M.; Bialer, M. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain. Br. J. Pharmacol., 2005, 146, 198-208. (Pubitemid 43079959)
    • (2005) British Journal of Pharmacology , vol.146 , Issue.2 , pp. 198-208
    • Winkler, I.1    Blotnik, S.2    Shimshoni, J.3    Yagen, B.4    Devor, M.5    Bialer, M.6
  • 126
    • 0034844676 scopus 로고    scopus 로고
    • Anticonvulsant profile of valrocemide (TV1901): A new antiepileptic drug
    • DOI 10.1046/j.1528-1157.2001.042007831.x
    • Isoherranen, N.; Woodhead, J. H.; White, H. S.; Bialer, M. Anticonvulsant profile of valrocemide (TV1901): a new antiepileptic drug. Epilepsia, 2001, 42, 831-836. (Pubitemid 32783089)
    • (2001) Epilepsia , vol.42 , Issue.7 , pp. 831-836
    • Isherranen, N.1    Woodhead, J.H.2    Steve White, H.3    Bialer, M.4
  • 127
    • 39049159090 scopus 로고    scopus 로고
    • Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide
    • Kaufmann, D.; Yagen, B.; Minert, A.; Tal, M.; Devor, M.; Bialer, M. Evaluation of the enantioselective antiallodynic and pharmacokinetic profile of propylisopropylacetamide, a chiral isomer of valproic acid amide. Neuropharmacol., 2008, 54, 699-707.
    • (2008) Neuropharmacol. , vol.54 , pp. 699-707
    • Kaufmann, D.1    Yagen, B.2    Minert, A.3    Tal, M.4    Devor, M.5    Bialer, M.6
  • 128
    • 0012677096 scopus 로고    scopus 로고
    • Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid
    • DOI 10.1023/A:1018960722284
    • Spiegelstein, O.; Yagen, B.; Levy, R. H.; Finnell, R. H.; Bennett, G. D.; Roeder, M.; Schurig, V.; Bialer, M. Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid. Pharm. Res., 1999, 16, 1582-1588. (Pubitemid 29510556)
    • (1999) Pharmaceutical Research , vol.16 , Issue.10 , pp. 1582-1588
    • Spiegelstein, O.1    Yagen, B.2    Levy, R.H.3    Finnell, R.H.4    Bennett, G.D.5    Roeder, M.6    Schurig, V.7    Bialer, M.8
  • 129
    • 70949087351 scopus 로고    scopus 로고
    • Synthesisand evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues
    • Kaufmann, D.; Bialer, M.; Shimshoni, J. A.; Devor, M.; Yagen, B. Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues. J. Med. Chem., 2009, 52, 7236-7248.
    • (2009) J. Med. Chem. , vol.52 , pp. 7236-7248
    • Kaufmann, D.1    Bialer, M.2    Shimshoni, J.A.3    Devor, M.4    Yagen, B.5
  • 130
    • 0026709603 scopus 로고
    • The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats
    • Fink-Jensen, A.; Suzdak, P. D.; Swedberg, M. D.; Judge, M. E.; Hansen, L.; Nielsen, P. G. The gamma-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. Eur. J. Pharmacol., 1992, 220, 197-201.
    • (1992) Eur. J. Pharmacol. , vol.220 , pp. 197-201
    • Fink-Jensen, A.1    Suzdak, P.D.2    Swedberg, M.D.3    Judge, M.E.4    Hansen, L.5    Nielsen, P.G.6
  • 131
    • 14044275666 scopus 로고    scopus 로고
    • Tiagabine as add-on therapy may be more effective with valproic acid - Open label, multicentre study of patients with focal epilepsy
    • DOI 10.1111/j.1468-1331.2004.00874.x
    • Jedrzejczak, J. Tiagabine as add-on therapy may be more effective with valproic acid - open label , multicentre study of patients with focal epilepsy. Eur. J. Neurol., 2005, 12, 176-180. (Pubitemid 40278523)
    • (2005) European Journal of Neurology , vol.12 , Issue.3 , pp. 176-180
    • Jedrzejczak, J.1
  • 132
    • 4344634460 scopus 로고    scopus 로고
    • Treating refractory epilepsy with tiagabine: Clinical experience
    • McKee, P. Treating refractory epilepsy with tiagabine: clinical experience. Seizure, 2004, 13, 478-480.
    • (2004) Seizure , vol.13 , pp. 478-480
    • McKee, P.1
  • 133
    • 0031710115 scopus 로고    scopus 로고
    • An evaluation of the GABA uptake blocker tiagabine in animal models of neuropathic and nociceptive pain
    • DOI 10.1002/(SICI)1098-2299(199806/07)44:2/3<106::AID-DDR8>3.0. CO;2-Q
    • Giardina, W. J.; Decker, M. W.; Porsolt, R. D.; Roux, S.; Collins, S. D.; Kim, D. J. B.; Bannon, A. W. An evaluation of the GABA uptake blocker tiagabine in animal models of neuropathic and nociceptive pain. Drug Dev. Res., 1998, 44, 106-113. (Pubitemid 28452882)
    • (1998) Drug Development Research , vol.44 , Issue.2-3 , pp. 106-113
    • Giardina, W.J.1    Decker, M.W.2    Porsolt, R.D.3    Roux, S.4    Collins, S.D.5    Kim, D.J.B.6    Bannon, A.W.7
  • 136
    • 49349088533 scopus 로고    scopus 로고
    • Dose-response relationship analysis of vigabatrin doses and their antinociceptive effects in the hot-plate test in mice
    • Luszczki, J. J.; Czuczwar, S. J. Dose-response relationship analysis of vigabatrin doses and their antinociceptive effects in the hot-plate test in mice. Pharmacol. Rep., 2008, 60, 409-414.
    • (2008) Pharmacol. Rep. , vol.60 , pp. 409-414
    • Luszczki, J.J.1    Czuczwar, S.J.2
  • 137
    • 1642355074 scopus 로고    scopus 로고
    • Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines
    • DOI 10.1016/j.ejphar.2003.08.033, PII S0014299903022453
    • Fuks, B.; Gillard, M.; Michel, P.; Lynch, B.; Vertongen, P.; Leprince, P.; Klitgaard, H.; Chatelain, P. Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines. Eur. J. Pharmacol., 2003, 478, 11-19. (Pubitemid 38366069)
    • (2003) European Journal of Pharmacology , vol.478 , Issue.1 , pp. 11-19
    • Fuks, B.1    Gillard, M.2    Michel, P.3    Lynch, B.4    Vertongen, P.5    Leprince, P.6    Klitgaard, H.7    Chatelain, P.8
  • 138
    • 25444446397 scopus 로고    scopus 로고
    • 3H]ucb 30889 binding to synaptic vesicle protein 2A in the rat spinal cord
    • DOI 10.1016/j.ejphar.2005.07.029, PII S0014299905007636
    • Lambeng, N.; Gillard, M.; Vertongen, P.; Fuks, B.; Chatelain, P. Characterization of [(3)H]ucb 30889 binding to synaptic vesicle protein 2A in the rat spinal cord. Eur. J. Pharmacol., 2005, 520, 70-76. (Pubitemid 41375813)
    • (2005) European Journal of Pharmacology , vol.520 , Issue.1-3 , pp. 70-76
    • Lambeng, N.1    Gillard, M.2    Vertongen, P.3    Fuks, B.4    Chatelain, P.5
  • 139
    • 0032563178 scopus 로고    scopus 로고
    • Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
    • DOI 10.1016/S0014-2999(98)00410-5, PII S0014299998004105
    • Klitgaard, H.; Matagne, A.; Gobert, J.; Wülfert, E. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur. J. Pharmacol., 1998, 353, 191-206. (Pubitemid 28352266)
    • (1998) European Journal of Pharmacology , vol.353 , Issue.2-3 , pp. 191-206
    • Klitgaard, H.1    Matagne, A.2    Gobert, J.3    Wulfert, E.4
  • 141
    • 54549099083 scopus 로고    scopus 로고
    • Effect of levetiracetam on the postmastectomy pain syndrome
    • Vilholm, O. J.; Cold, S.; Rasmussen, L.; Sindrup, S. H. Effect of levetiracetam on the postmastectomy pain syndrome. Eur. J. Neurol., 2008, 15, 851-857.
    • (2008) Eur. J. Neurol. , vol.15 , pp. 851-857
    • Vilholm, O.J.1    Cold, S.2    Rasmussen, L.3    Sindrup, S.H.4
  • 142
    • 79959376036 scopus 로고    scopus 로고
    • The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: A randomized, placebo-controlled, cross-over trial
    • Holbech, J. V.; Otto, M.; Bach, F. W.; Jensen, T. S.; Sindrup, S. H. The anticonvulsant levetiracetam for the treatment of pain in polyneuropathy: a randomized, placebo-controlled, cross-over trial. Eur. J. Pain, 2011, 15, 608-614.
    • (2011) Eur. J. Pain , vol.15 , pp. 608-614
    • Holbech, J.V.1    Otto, M.2    Bach, F.W.3    Jensen, T.S.4    Sindrup, S.H.5
  • 144
    • 53449102055 scopus 로고    scopus 로고
    • New molecular targets for antiepileptic drugs: α2δ, SV2A, and Kv7/KCNQ/M potassium channels
    • Rogawski, M. A.; Bazil, C. W. New molecular targets for antiepileptic drugs: α2δ, SV2A, and Kv7/KCNQ/M potassium channels. Curr. Neurol. Neurosci. Rep., 2008, 8, 345-352.
    • (2008) Curr. Neurol. Neurosci. Rep. , vol.8 , pp. 345-352
    • Rogawski, M.A.1    Bazil, C.W.2
  • 145
    • 79960445898 scopus 로고    scopus 로고
    • Brivaracetam for the treatment of epilepsy
    • Epub ahead of print
    • Schulze-Bonhage, A. Brivaracetam for the treatment of epilepsy. Expert Opin. on Pharmacother., 2011, [Epub ahead of print].
    • (2011) Expert Opin. on Pharmacother.
    • Schulze-Bonhage, A.1
  • 147
    • 0035840856 scopus 로고    scopus 로고
    • NMDA receptors as targets for drug action in neuropathic pain
    • DOI 10.1016/S0014-2999(01)01307-3, PII S0014299901013073
    • Parsons, C. G. NMDA receptors as targets for drug action in neuropathic pain. Eur. J. Pharmacol., 2001, 429, 71-78. (Pubitemid 33043983)
    • (2001) European Journal of Pharmacology , vol.429 , Issue.1-3 , pp. 71-78
    • Parsons, C.G.1
  • 149
    • 0036119716 scopus 로고    scopus 로고
    • Early clinical experience with the novel NMDA receptor antagonist CNS 5161
    • DOI 10.1046/j.0306-5251.2001.01541.x
    • Walters, M. R.; Bradford, A. P. J.; Fischer, J.; Lees, K. R. Early clinical experience with the novel NMDA receptor antagonist CNS 5161. Br. J. Clin. Pharmacol., 2002, 53, 305-311. (Pubitemid 34226973)
    • (2002) British Journal of Clinical Pharmacology , vol.53 , Issue.3 , pp. 305-311
    • Walters, M.R.1    Bradford, A.P.J.2    Fischer, J.3    Lees, K.R.4
  • 150
    • 6844257516 scopus 로고    scopus 로고
    • Synthesis and pharmacological evaluation of N-(2,5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-D-aspartate receptor ion-channel blockers
    • DOI 10.1021/jm970459c
    • Hu, L. Y.; Guo, J.; Magar, S. S.; Fischer, J. B.; Burke-Howie, K. J.; Durant, G. J. Synthesis and pharmacological evaluation of N-(2, 5-disubstituted phenyl)-N'-(3-substituted phenyl)-N'-methylguanidines as N-methyl-Daspartate receptor ion-channel blockers. J. Med. Chem., 1997, 40, 4281-4289. (Pubitemid 28042307)
    • (1997) Journal of Medicinal Chemistry , vol.40 , Issue.26 , pp. 4281-4289
    • Hu, L.-Y.1    Quo, J.2    Magar, S.S.3    Fischer, J.B.4    Burke-Howie, K.J.5    Durant, G.J.6
  • 151
    • 34250664524 scopus 로고    scopus 로고
    • Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain
    • DOI 10.1111/j.1365-2125.2007.02880.x
    • Forst, T.; Smith, T.; Schütte, K.; Marcus, P.; Pfützner, A. Dose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic pain. Br. J. Clin. Pharmacol., 2007, 64, 75-82. (Pubitemid 46934426)
    • (2007) British Journal of Clinical Pharmacology , vol.64 , Issue.1 , pp. 75-82
    • Forst, T.1    Smith, T.2    Schutte, K.3    Marcus, P.4    Pfutzner, A.5
  • 152
    • 0036203057 scopus 로고    scopus 로고
    • Neuroprotective potential of ionotropic glutamate receptor antagonists
    • DOI 10.1080/10298420290015872
    • Danysz, W.; Parsons, C. G. Neuroprotective potential of ionotropic glutamate receptor antagonists. Neurotox. Res., 2002, 4, 119-126. (Pubitemid 34285054)
    • (2002) Neurotoxicity Research , vol.4 , Issue.2 , pp. 119-126
    • Danysz, W.1    Parsons, C.G.2
  • 154
    • 33947188651 scopus 로고    scopus 로고
    • Effect of novel AMPA antagonist, NS1209, on status epilepticus. An experimental study in rat
    • DOI 10.1016/j.eplepsyres.2006.12.004, PII S0920121107000034
    • Pitkänen, A.; Mathiesen, C.; Rønn, L. C. B.; Møller, A.; Nissinen, J. Effect of novel AMPA antagonist, NS1209, on status epilepticus. An experimental study in rat. Epilepsy Res., 2007, 74, 45-54. (Pubitemid 46413707)
    • (2007) Epilepsy Research , vol.74 , Issue.1 , pp. 45-54
    • Pitkanen, A.1    Mathiesen, C.2    Ronn, L.C.B.3    Moller, A.4    Nissinen, J.5
  • 155
    • 3242740258 scopus 로고    scopus 로고
    • Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain
    • DOI 10.1016/j.neuropharm.2004.04.007, PII S0028390804001133
    • Blackburn-Munro, G.; Bomholt, S. F.; Erichsen, H. K. Behavioural effects of the novel AMPA/GluR5 selective receptor antagonist NS1209 after systemic administration in animal models of experimental pain. Neuropharmacol., 2004, 47, 351-362. (Pubitemid 38953226)
    • (2004) Neuropharmacology , vol.47 , Issue.3 , pp. 351-362
    • Blackburn-Munro, G.1    Bomholt, S.F.2    Erichsen, H.K.3
  • 156
    • 63849275646 scopus 로고    scopus 로고
    • The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: A randomized, double-blind, placebo-controlled, three-way crossover study
    • Gormsen, L.; Finnerup, N. B.; Almqvist, P. M.; Jensen, T S. The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study. Anesth. Analg., 2009, 108, 1311-1319.
    • (2009) Anesth. Analg. , vol.108 , pp. 1311-1319
    • Gormsen, L.1    Finnerup, N.B.2    Almqvist, P.M.3    Jensen, T.S.4
  • 157
    • 34548383403 scopus 로고    scopus 로고
    • Drug profile: Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain
    • Mattia, C.; Coluzzi, F. Indantadol, a novel NMDA antagonist and nonselective MAO inhibitor for the potential treatment of neuropathic pain. IDrugs, 2007, 10, 636-644. (Pubitemid 47360927)
    • (2007) IDrugs , vol.10 , Issue.9 , pp. 636-644
    • Mattia, C.1    Coluzzi, F.2
  • 158
    • 24644475145 scopus 로고    scopus 로고
    • CHF3381, a novel antinociceptive agent, attenuates capsaicin-induced pain in rats
    • DOI 10.1016/j.ejphar.2005.07.004, PII S001429990500734X
    • Bassani, F.; Bergamaschi, M.; Tonino Bolzoni, P.; Villetti, G. CHF3381, a novel antinociceptive agent, attenuates capsaicin-induced pain in rats. Eur. J. Pharmacol., 2005, 519, 231-236. (Pubitemid 41278543)
    • (2005) European Journal of Pharmacology , vol.519 , Issue.3 , pp. 231-236
    • Bassani, F.1    Bergamaschi, M.2    Bolzoni, P.T.3    Villetti, G.4
  • 160
  • 162
    • 0035219751 scopus 로고    scopus 로고
    • Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse
    • PII S002839080000112X
    • Rogawski, M. A.; Kurzman, P. S.; Yamaguchi, S.; Li, H. Role of AMPA and GluR5 kainate receptors in the development and expression of amygdale kindling in the mouse. Neuropharmacol., 2000, 40, 28-35. (Pubitemid 33779797)
    • (2001) Neuropharmacology , vol.40 , Issue.1 , pp. 28-35
    • Rogawski, M.A.1    Kurzman, P.S.2    Yamaguchi, S.-I.3    Li, H.4
  • 163
    • 0031771639 scopus 로고    scopus 로고
    • AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans
    • Sang, C. N.; Hostetter, M. P.; Gracely, R. H.; Chappell, A. S.; Schoepp, D. D.; Lee, G.; Whitcup, S.; Caruso, R.; Max, M. B. AMPA/kainate antagonist LY293558 reduces capsaicin-evoked hyperalgesia but not pain in normal skin in humans. Anesthesiology, 1998, 89, 1060-1067. (Pubitemid 28516529)
    • (1998) Anesthesiology , vol.89 , Issue.5 , pp. 1060-1067
    • Sang, C.N.1    Hostetter, M.P.2    Gracely, R.H.3    Chappell, A.S.4    Schoepp, D.D.5    Lee, G.6    Whitcup, S.7    Caruso, R.8    Max, M.B.9
  • 164
    • 77955682813 scopus 로고    scopus 로고
    • What is the promise of new antiepileptic drugs in status epilepticus? Focus on brivaracetam, carisbamate, lacosamide, NS-1209, and topiramate
    • Perucca, E. What is the promise of new antiepileptic drugs in status epilepticus? Focus on brivaracetam, carisbamate, lacosamide, NS-1209, and topiramate. Epilepsia, 2009, 50 Suppl 1, 49-50.
    • (2009) Epilepsia , vol.50 , Issue.SUPPL. 1 , pp. 49-50
    • Perucca, E.1
  • 165
    • 60649085542 scopus 로고    scopus 로고
    • Oral pregabalin reverses cold allodynia in two distinct models of peripheral neuropathic pain
    • Gustafsson, H.; Sandin, J. Oral pregabalin reverses cold allodynia in two distinct models of peripheral neuropathic pain. Eur. J. Pharmacol., 2009, 605, 103-108.
    • (2009) Eur. J. Pharmacol. , vol.605 , pp. 103-108
    • Gustafsson, H.1    Sandin, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.