Gabapentin in naive childhood absence epilepsy: Results from two double- blind, placebo-controlled, multicenter studies

Journal of Child Neurology

Volumn 11, Issue 6, 1996, Pages 470-475

  Trudeau, Virginia ^a,d   Myers, Sharie ^a   LaMoreaux, Linda ^a   Anhut, Henning ^b   Garofalo, Elizabeth ^a   Ebersole, John ^c  

^a PFIZER INC   (United States)

^b Division of Warner Lambert Company   (Germany)

^c VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^d Central Nervous System   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; GABAPENTIN;

ABSENCE; ADOLESCENT; ANTICONVULSANT THERAPY; ARTICLE; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; EPILEPSY; FEMALE; HUMAN; MALE; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEIZURE; SOMNOLENCE; TREATMENT OUTCOME; VERTIGO;

EID: 0029803259     PISSN: 08830738     EISSN: None     Source Type: Journal    
DOI: 10.1177/088307389601100611     Document Type: Article

References (11)

1. Pearl PL, Holmes GL: Absence seizures, in Dodson WE, Pellock JM (eds): Pediatric Epilepsy: Diagnosis and Therapy. New York, Demos Publications, 1993, pp 157-169.
2. Voltmer K-O, von Hodenberg A, Kolle EU: Pharmacokinetics and metabolism of gabapentin in rat, dog and man. Arzneimittelforschung 1986;36:830-839.
3. Ojemann LM, Friel PN, Ojemann GA: Gabapentin concentrations in human brain, abstract. Epilepsia 1988;29:694.
4. 3H] Gabapentin may label a system-L-like neutral amino acid carrier in brain. Eur J Pharmacol 1993;247:341-345.
5. Richens A: Clinical pharmacokinetics of gabapentin, in Chadwick D (ed): New Trends in Epilepsy Management: The Role of Gabapentin. International Congress and Symposium Series, London, Royal Society of Medicine Services Ltd, 1993, pp 41-46. Presented at Satellite Symposium during Epilepsy Europe; September 3, 1992, Glasgow.
6. Anhut H, Ashman P, Feuerstein TJ, et al: Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: A double-blind, placebo-controlled study. Epilepsia 1994;35:795-801.
7. Dreifuss FE, Martinez-Lage M, Roger J, et al: Proposal for classification of epilepsies and epileptic syndromes. Commission on classification and terminology of the International League Against Epilepsy. Epilepsia 1985;26:268-278.
8. Browne TR, Dreifuss FE, Penry JK, et al: Clinical and EEG estimates of absence seizure frequency. Arch Neurol 1983; 40:469-472.
9. Ebersole JS, Bridgers SL: Direct comparison of 3- and 8-channel ambulatory cassette EEG with intensive inpatient monitoring. Neurology 1985;35:846-854.
10. COSTART Coding Symbols for a Thesaurus of Adverse Reaction Terms, 2nd ed. Washington, DC, Department of Health and Human Services, FDA, 1985.
11. Braathen G, Theorell K, Persson A, Rane A: Valproate in the treatment of absence epilepsy in children: A study of dose-response relationships. Epilepsia 1988;29:548-552.