Gene conversion tracts from double-strand break repair in mammalian cells

Molecular and Cellular Biology

Volumn 18, Issue 1, 1998, Pages 93-101

  Elliott, Beth ^a   Richardson, Christine ^a   Winderbaum, Jamie ^a   Nickoloff, Jac A ^b   Jasin, Maria ^a,c  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; EMBRYO; GENE CONVERSION; GENE TARGETING; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

ANIMALIA; MAMMALIA;

EID: 0031962185     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.18.1.93     Document Type: Article

References (45)

1. Ahn, B.-Y., K. J. Dornfeld, T. J. Fagrelius, and D. M. Livingston. 1988. Effect of limited homology on gene conversion in a Saccharomyces cerevisiae plasmid recombination system. Mol. Cell. Biol. 8:2442-2448.
2. Bailis, A. M., L. Arthur, and R. Rothstein. 1990. A defect in mismatch repair in Saccharomyces cerevisiae stimulates ectopic recombination between homeologous genes by an excision repair dependent process. Genetics 126: 535-547.
3. Brown, T. C., and J. Jiricny. 1988. Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells. Cell 54: 705-711.
4. Cao, L., E. Alani, and N. Kleckner. 1990. A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61:1089-1101.
5. Chambers, S. R., N. Hunter, E. J. Louis, and R. H. Borts. 1996. The mismatch repair system reduces meiotic homeologous recombination and stimulates recombination-dependent chromosome loss. Mol. Cell. Biol. 16:6110-6120.
6. Choulika, A., A. Perrin, B. Dujon, and J.-F. Nicolas. 1995. Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol. Cell. Biol. 15:1968-1973.
7. de Wind, N., M. Dekker, A. Berns, M. Radman, and H. te Riele. 1995. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 82:321-330.
8. Donoho, G., M. Jasin, and P. Berg. Unpublished results.
9. Ferguson, D. O., and W. K. Holloman. 1996. Recombinational repair of gaps in DNA is asymmetric in Ustilago maydis and can be explained by a migrating D-loop model. Proc. Natl. Acad. Sci. USA 93:5419-5424.
10. Godwin, A. R., R. J. Bollag, D.-M. Christie, and R. M. Liskay. 1994. Spontaneous and restriction enzyme-induced chromosomal recombination in mammalian cells. Proc. Natl. Acad. Sci. USA 91:12554-12558.
11. Haber, J. E. 1995. In rivo biochemistry: physical monitoring of recombination induced by site-specific endonucleases. BioEssays 17:609-620.
12. Jackson, S. P., and P. A. Jeggo. 1995. DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci. 20: 412-415.
13. Jasin, M. 1996. Genetic manipulation of genomes with rare-cutting endonucleases. Trends Genet. 12:224-228.
14. Kogoma, T. 1996. Recombination by replication. Cell 85:625-627.
15. Liang, F., P. J. Romanienko, D. T. Weaver, P. A. Jeggo, and M. Jasin. 1996. Chromosomal double-strand break repair in Ku80 deficient cells. Proc. Natl. Acad. Sci. USA 93:8929-8933.
16. Lin, F.-L., K. Sperle, and N. Sternberg. 1990. Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a nonconservative pathway that leads to crossover products. Mol. Cell. Biol. 10:103-112.
17. Lukacsovich, T., D. Yang, and A. S. Waldman. 1994. Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI. Nucleic Acids Res. 22:5649-5657.
18. Malkova, A., E. L. Ivanov, and J. E. Haber. 1996. Double-strand break repair in the absence of RAD51 in yeast: a possible role for break-induced replication. Proc. Natl. Acad. Sci. USA 93:7131-7136.
19. Modrich, P. 1991. Mechanisms and biological effects of mismatch repair. Annu. Rev. Genet. 25:229-253.
20. Moynahan, M. E., and M. Jasin. 1997. Loss of heterozygosity induced by a chromosomal double-strand break. Proc. Natl. Acad. Sci. USA 94:8988-8993.
21. Petes, T. D., R. E. Malone, and L. S. Symington. 1991. Recombination in yeast, p. 407-521. In J. R. Broach, J. R. Pringle, and E. W. Jones (ed.), The molecular and cellular biology of the yeast Saccharomyces: genome dynamics, protein synthesis, and energetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
22. Phillips, J. W., and W. F. Morgan. 1994. Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome. Mol. Cell. Biol. 14:5794-5803.
23. Priebe, S. D., J. Westmoreland, T. Nilsson-Tillgren, and M. A. Resnick. 1994. Induction of recombination between homologous diverged DNAs by double-strand caps and breaks and role of mismatch repair. Mol. Cell. Biol. 14:48024814.
24. Ray, B. L., C. I. White, and J. E. Haber. 1991. Heteroduplex formation and mismatch repair of the "stuck" mutation during mating-type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 11:5372-5380.
25. Rayssiguier, C., D. S. Thaler, and M. Radman. 1989. The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature 342:396-401.
26. Resnick, M. 1976. The repair of double-strand breaks in DNA; a model involving recombination. J. Theor. Biol. 59:97-109.
27. Robertson, E. J. 1987. Embryo-derived stem cell lines, p. 71-112. In E. J. Robertson (ed.), Teratocarcinomas and embryonic stem cells: a practical approach. IRL Press, Washington, D.C.
28. Rouet, P., F. Smih, and M. Jasin. 1994. Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Mol. Cell. Biol. 14:8096-8106.
29. Rouet, P., F. Smih, and M. Jasin. 1994. Expression of site-specific endonuclease stimulates recombination in mammalian cells. Proc. Natl. Acad. Sci. USA 91:6064-6068.
30. Sargent, R. G., M. A. Brenneman, and J. H. Wilson. 1997. Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination. Mol. Cell. Biol. 17:267-277.
31. Schneider, W. P., B. P. Nichols, and C. Yanofsky. 1981. Procedure for production of hybrid genes and proteins and its use in assessing significance of amino acid differences in homologous tryptophan synthetase α polypeptides. Proc. Natl. Acad. Sci. USA 78:2169-2173.
32. Schwacha, A., and N. Kleckner. 1995. Identification of double Holliday junctions as intermediates in meiotic recombination. Cell 83:783-791.
33. Shen, P., and H. V. Huang. 1986. Homologous recombination in Escherichia coli: dependence on substrate length and homology. Genetics 112:441-457.
34. Shinohara, A., and T. Ogawa. 1995. Homologous recombination and the role of double-strand breaks. Trends Biochem. 20:387-391.
35. Smih, F., P. Rouet, P. J. Romanienko, and M. Jasin. 1995. Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells. Nucleic Acids Res. 23:5012-5019.
36. Stahl, F. 1996. Meiotic recombination in yeast: coronation of the double-strand-break repair model. Cell 87:965-968.
37. Sugawara, N., and J. E. Haber. 1992. Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol. 12:563-575.
38. Sun, H., D. Treco, N. P. Schultes, and J. W. Szostak. 1989. Double-strand breaks at an initiation site for meiotic gene conversion. Nature 338:87-90.
39. Sweetser, D. B., H. Hough, J. F. Whelden, M. Arbuckle, and J. A. Nickoloff. 1994. Fine-resolution mapping of spontaneous and double-strand break-induced gene conversion tracts in Saccharomyces cerevisiae reveals reversible mitotic conversion polarity. Mol. Cell. Biol. 14:3863-3875.
40. Szostak, J. W., T. L. Orr-Weaver, R. J. Rothstein, and F. W. Stahl. 1983. The double-strand-break repair model for recombination. Cell 33:25-35.
41. Taghian, D. G., and J. A. Nickoloff. Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells. Mol. Cell. Biol. 17:6386-6393.
42. te Riele, H., E. R. Maandag, and A. Berns. 1992. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. USA 89:5128-5132.
43. Thomas, K. R., and M. R. Capecchi. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503-512.
44. Waldman, A. S., and R. M. Liskay. 1987. Differential effects of base-pair mismatch on intrachromsomal versus extrachromsomal recombination in mouse cells. Proc. Natl. Acad. Sci. USA 84:5340-5344.
45. Waldman, A. S., and R. M. Liskay. 1988. Dependence of intrachromosomal recombination in mammalian cells on uninterrupted homology. Mol. Cell. Biol. 8:5350-5357.