Frequent endonuclease cleavage at off-target locations in vivo

Molecular Therapy

Volumn 18, Issue 5, 2010, Pages 983-986

  Petek, Lisa M ^a,b   Russell, David W ^b   Miller, Daniel G ^a,b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; PARVOVIRUS VECTOR; PROTEIN I SCEI; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME; DNA SEQUENCE; DNA STRAND BREAKAGE; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IN VIVO STUDY; PROTEIN CLEAVAGE;

CELL LINE; DEPENDOVIRUS; DNA BREAKS, DOUBLE-STRANDED; ENDONUCLEASES; GENETIC VECTORS; HUMANS;

ADENO-ASSOCIATED VIRUS;

EID: 77952008829     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2010.35     Document Type: Article

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