O6-Methylguanine-DNA methyltransferase (MGMT) in normal tissues and tumors: Enzyme activity, promoter methylation and immunohistochemistry

Biochimica et Biophysica Acta - Reviews on Cancer

Volumn 1816, Issue 2, 2011, Pages 179-190

  Christmann, Markus ^a   Verbeek, Barbara ^a   Roos, Wynand P ^a   Kaina, Bernd ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Alkyltransferase; DNA repair; Drug resistance; MGMT; O6 methylguanine DNA methyltransferase; Promoter methylation

Indexed keywords

6 O BENZYLGUANINE; ALKYLATING AGENT; CARMUSTINE; CORTICOSTEROID; DACARBAZINE; FOTEMUSTINE; LOMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NIMUSTINE; STREPTOZOCIN; TEMOZOLOMIDE;

BRAIN EDEMA; BRAIN METASTASIS; BRAIN TUMOR; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STEM CELL; CANCER SUSCEPTIBILITY; CANCER TISSUE; CHILDHOOD CANCER; CPG ISLAND; DEVELOPMENTAL STAGE; DNA METHYLATION; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME ASSAY; EPIGENETICS; GLIOBLASTOMA; GLIOMA; HUMAN; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MELANOMA; METASTASIS; METASTATIC MELANOMA; NEOPLASM; NONHUMAN; PANCREAS CANCER; PHASE 2 CLINICAL TRIAL (TOPIC); POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVIEW; TRANSCRIPTION REGULATION; TREATMENT RESPONSE; UPREGULATION;

ANIMALS; DNA METHYLATION; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASMS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PROGNOSIS; PROMOTER REGIONS, GENETIC;

NICOTIANA TABACUM;

EID: 79960656490     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2011.06.002     Document Type: Review

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