Enforced expression of wild-type p53 curtails the transcription of the O6-methylguanine-DNA methyltransferase gene in human tumor cells and enhances their sensitivity to alkylating agents

Clinical Cancer Research

Volumn 7, Issue 5, 2001, Pages 1398-1409

  Srivenugopal, K S ^a   Shou, J ^a   Mullapudi, S R S ^a   Lang F F , Jr ^a   Rao, J S ^a   Ali Osman, F ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CARMUSTINE; DEXAMETHASONE; MESSENGER RNA; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN P53; TEMOZOLOMIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER RESISTANCE; COLON CANCER; CONTROLLED STUDY; DNA REPAIR; GLIOBLASTOMA; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; CELL DIVISION; CELL LINE; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; HUMANS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PEPTIDE HYDROLASES; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

EID: 0034901404     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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