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Volumn 13, Issue 7, 2007, Pages 2038-2045

Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CARMUSTINE; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; IRINOTECAN; LOMUSTINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROCARBAZINE; PROTEIN MSH6; TEMOZOLOMIDE; TIOGUANINE; VINCRISTINE;

EID: 34247499001     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-2149     Document Type: Article
Times cited : (360)

References (37)
  • 1
    • 33645732219 scopus 로고    scopus 로고
    • Molecular pathology of malignant gliomas
    • Louis DN. Molecular pathology of malignant gliomas. Annu Rev Pathol Mech Dis 2006;1:97-117.
    • (2006) Annu Rev Pathol Mech Dis , vol.1 , pp. 97-117
    • Louis, D.N.1
  • 2
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-96.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 3
    • 33646256145 scopus 로고    scopus 로고
    • A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy
    • Hunter C, Smith R, Cahill DP, et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Res 2006;66:3987-91.
    • (2006) Cancer Res , vol.66 , pp. 3987-3991
    • Hunter, C.1    Smith, R.2    Cahill, D.P.3
  • 4
    • 3042531072 scopus 로고    scopus 로고
    • Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells
    • Guo G, Wang W, Bradley A. Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells. Nature 2004;429:891-5.
    • (2004) Nature , vol.429 , pp. 891-895
    • Guo, G.1    Wang, W.2    Bradley, A.3
  • 5
    • 0032851842 scopus 로고    scopus 로고
    • Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
    • Hickman MJ, Samson LD. Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents. Proc Natl Acad Sci U S A 1999;96: 10764-9.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10764-10769
    • Hickman, M.J.1    Samson, L.D.2
  • 6
  • 8
    • 19644386509 scopus 로고    scopus 로고
    • Characterization of the mismatch repair defect in the human lymphoblastold MT1 cells
    • Szadkowski M, Iaccarino I, Heinimann K, Marra G, Jiricny J. Characterization of the mismatch repair defect in the human lymphoblastold MT1 cells. Cancer Res 2005;65:4525-9.
    • (2005) Cancer Res , vol.65 , pp. 4525-4529
    • Szadkowski, M.1    Iaccarino, I.2    Heinimann, K.3    Marra, G.4    Jiricny, J.5
  • 9
    • 0030776227 scopus 로고    scopus 로고
    • Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
    • Umar A, Koi M, Risinger JI, et al. Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res 1997;57:3949-55.
    • (1997) Cancer Res , vol.57 , pp. 3949-3955
    • Umar, A.1    Koi, M.2    Risinger, J.I.3
  • 10
    • 0033065150 scopus 로고    scopus 로고
    • Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15
    • Lettieri T, Marra G, Aquilina G, et al. Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15. Carcinogenesis 1999;20:373-82.
    • (1999) Carcinogenesis , vol.20 , pp. 373-382
    • Lettieri, T.1    Marra, G.2    Aquilina, G.3
  • 11
    • 33646187811 scopus 로고    scopus 로고
    • The multifaceted mismatch-repair system
    • Jiricny J. The multifaceted mismatch-repair system. Nat Rev Mol Cell Biol 2006;7:335-46.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 335-346
    • Jiricny, J.1
  • 12
    • 27644596327 scopus 로고    scopus 로고
    • A homozygous mutation in MSH6 causes Turcot syndrome
    • Hegde MR, Chong B, Blazo ME, et al. A homozygous mutation in MSH6 causes Turcot syndrome. Clin Cancer Res 2005;11:4689-93.
    • (2005) Clin Cancer Res , vol.11 , pp. 4689-4693
    • Hegde, M.R.1    Chong, B.2    Blazo, M.E.3
  • 13
    • 16544395180 scopus 로고    scopus 로고
    • A homozygous MSH6 mutation in a child with cafe-au-lait spots, oligodendroglioma and rectal cancer
    • Menko FH, Kaspers GL, Meijer GA, Claes K, van Hagen JM, Gille JJ. A homozygous MSH6 mutation in a child with cafe-au-lait spots, oligodendroglioma and rectal cancer. Fam Cancer 2004;3:123-7.
    • (2004) Fam Cancer , vol.3 , pp. 123-127
    • Menko, F.H.1    Kaspers, G.L.2    Meijer, G.A.3    Claes, K.4    van Hagen, J.M.5    Gille, J.J.6
  • 14
    • 2442708840 scopus 로고    scopus 로고
    • Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history
    • Buttin BM, Powell MA, Mutch DG, et al. Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history. Am J Hum Genet 2004;74:1262-9.
    • (2004) Am J Hum Genet , vol.74 , pp. 1262-1269
    • Buttin, B.M.1    Powell, M.A.2    Mutch, D.G.3
  • 15
    • 18244380349 scopus 로고    scopus 로고
    • Molecular and clinical characteristics of MSH6 variants: An analysis of 25 index carriers of a germline variant
    • Berends MJ, Wu Y, Sijmons RH, et al. Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant. Am J Hum Genet 2002;70:26-37.
    • (2002) Am J Hum Genet , vol.70 , pp. 26-37
    • Berends, M.J.1    Wu, Y.2    Sijmons, R.H.3
  • 16
    • 0028970197 scopus 로고
    • The molecular basis of Turcots syndrome
    • Hamilton SR, Liu B, Parsons RE, et al. The molecular basis of Turcots syndrome. N Engl J Med 1995;332: 839-47.
    • (1995) N Engl J Med , vol.332 , pp. 839-847
    • Hamilton, S.R.1    Liu, B.2    Parsons, R.E.3
  • 17
    • 20044372154 scopus 로고    scopus 로고
    • MGMT gene silencing and benefit from temozolomide in glioblastoma
    • Hegi ME, Diserens A, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005;352:997-1003.
    • (2005) N Engl J Med , vol.352 , pp. 997-1003
    • Hegi, M.E.1    Diserens, A.2    Gorlia, T.3
  • 18
    • 0032588748 scopus 로고    scopus 로고
    • 6-Methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: Frequency and time to tumor progression after alkylating agent-based chemotherapy
    • 6-Methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clin Cancer Res 1999;5:807-14.
    • (1999) Clin Cancer Res , vol.5 , pp. 807-814
    • Silber, J.R.1    Blank, A.2    Bobola, M.S.3    Ghatan, S.4    Kolstoe, D.D.5    Berger, M.S.6
  • 19
    • 11244327596 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas
    • 6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas. J Neurooncol 2004;70: 333-40.
    • (2004) J Neurooncol , vol.70 , pp. 333-340
    • Nakasu, S.1    Fukami, T.2    Baba, K.3    Matsuda, M.4
  • 20
    • 0034046394 scopus 로고    scopus 로고
    • Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents
    • Bearzatto A, Szadkowski M, Macpherson P, Jiricny J, Karran P. Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents. Cancer Res 2000;60:3262-70.
    • (2000) Cancer Res , vol.60 , pp. 3262-3270
    • Bearzatto, A.1    Szadkowski, M.2    Macpherson, P.3    Jiricny, J.4    Karran, P.5
  • 21
    • 0030479125 scopus 로고    scopus 로고
    • Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea
    • Liu LL, Markowitz S, Gerson SL. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Cancer Res 1996;56: 5375-9.
    • (1996) Cancer Res , vol.56 , pp. 5375-5379
    • Liu, L.L.1    Markowitz, S.2    Gerson, S.L.3
  • 22
    • 0442299319 scopus 로고
    • A semiparametric model for randomly truncated data
    • Wang M-C. A semiparametric model for randomly truncated data. J Am Stat Assoc 1989;84:742-8.
    • (1989) J Am Stat Assoc , vol.84 , pp. 742-748
    • Wang, M.-C.1
  • 23
    • 33745658837 scopus 로고    scopus 로고
    • Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer
    • Barnetson RA, Tenesa A, Farrington SM, et al. Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer. N Engl J Med 2006;354:2751-63.
    • (2006) N Engl J Med , vol.354 , pp. 2751-2763
    • Barnetson, R.A.1    Tenesa, A.2    Farrington, S.M.3
  • 24
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel H, Frankel WL, Martin E, et al. Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N Engl J Med 2005;352:1851-60.
    • (2005) N Engl J Med , vol.352 , pp. 1851-1860
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 25
    • 0032435612 scopus 로고    scopus 로고
    • DNA mismatch repair and O-6-alkylguanine-DNA alkyltransferase analysis and response to temodal in newly diagnosed malignant glioma
    • Friedman HS, McLendon RE, Kerby T, et al. DNA mismatch repair and O-6-alkylguanine-DNA alkyltransferase analysis and response to temodal in newly diagnosed malignant glioma. J Clin Oncol 1998;16: 3851-7.
    • (1998) J Clin Oncol , vol.16 , pp. 3851-3857
    • Friedman, H.S.1    McLendon, R.E.2    Kerby, T.3
  • 26
    • 0027502938 scopus 로고
    • Defective mismatch binding and a mutator phenotype in cells tolerant to DNA Damage
    • Branch P, Aquilina G, Bignami M, Karran P. Defective mismatch binding and a mutator phenotype in cells tolerant to DNA Damage. Nature 1993;362: 652-4.
    • (1993) Nature , vol.362 , pp. 652-654
    • Branch, P.1    Aquilina, G.2    Bignami, M.3    Karran, P.4
  • 28
    • 2442706833 scopus 로고    scopus 로고
    • Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells
    • Papouli E, Cejka P, Jiricny J. Dependence of the cytotoxicity of DNA-damaging agents on the mismatch repair status of human cells. Cancer Res 2004; 64:3391-4.
    • (2004) Cancer Res , vol.64 , pp. 3391-3394
    • Papouli, E.1    Cejka, P.2    Jiricny, J.3
  • 29
    • 0032694518 scopus 로고    scopus 로고
    • Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents
    • Liu L, Taverna P, Whitacre CM, Chatterjee S, Gerson SL. Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents. Clin Cancer Res 1999;5:2908-17.
    • (1999) Clin Cancer Res , vol.5 , pp. 2908-2917
    • Liu, L.1    Taverna, P.2    Whitacre, C.M.3    Chatterjee, S.4    Gerson, S.L.5
  • 30
    • 22244448679 scopus 로고    scopus 로고
    • The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
    • Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res 2005;65:6394-400.
    • (2005) Cancer Res , vol.65 , pp. 6394-6400
    • Trivedi, R.N.1    Almeida, K.H.2    Fornsaglio, J.L.3    Schamus, S.4    Sobol, R.W.5
  • 31
    • 0037310904 scopus 로고    scopus 로고
    • 6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl) 1-nitrosourea, and cisplatin
    • 6-alkylguanine-DNA alkyltransferase and mismatch repair activities on the sensitivity of human melanoma cells to temozolomide, 1,3-bis(2-chloroethyl) 1-nitrosourea, and cisplatin. J Pharmacol Exp Ther 2003;304:661-8.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 661-668
    • Pepponi, R.1    Marra, G.2    Fuggetta, M.P.3
  • 32
    • 9144268289 scopus 로고    scopus 로고
    • Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors
    • Vera K, Djafari L, Faivre S, et al. Dose-dense regimen of temozolomide given every other week in patients with primary central nervous system tumors. Ann Oncol 2004;15:161-71.
    • (2004) Ann Oncol , vol.15 , pp. 161-171
    • Vera, K.1    Djafari, L.2    Faivre, S.3
  • 33
    • 33646503204 scopus 로고    scopus 로고
    • ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O(6)-methylguanine adducts
    • Yoshioka K, Yoshioka Y, Hsieh P. ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O(6)-methylguanine adducts. Mol Cell 2006;22:501-10.
    • (2006) Mol Cell , vol.22 , pp. 501-510
    • Yoshioka, K.1    Yoshioka, Y.2    Hsieh, P.3
  • 34
    • 0036567603 scopus 로고    scopus 로고
    • Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSα mismatch-binding activity
    • Christmann M, Tomicic MT, Kaina B. Phosphorylation of mismatch repair proteins MSH2 and MSH6 affecting MutSα mismatch-binding activity. Nucleic Acids Res 2002;30:1959-66.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1959-1966
    • Christmann, M.1    Tomicic, M.T.2    Kaina, B.3
  • 35
    • 0029143992 scopus 로고
    • Evidence for a connection between the mismatch repair system and the G(2) cell-cycle checkpoint
    • Hawn MT, Umar A, Carethers JM, et al. Evidence for a connection between the mismatch repair system and the G(2) cell-cycle checkpoint. Cancer Res 1995;55:3721-5.
    • (1995) Cancer Res , vol.55 , pp. 3721-3725
    • Hawn, M.T.1    Umar, A.2    Carethers, J.M.3
  • 36
    • 0035266426 scopus 로고    scopus 로고
    • Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors
    • Alonso M, Hamelin R, Kim M, et al. Microsatellite instability occurs in distinct subtypes of pediatric but not adult central nervous system tumors. Cancer Res 2001;61:2124-8.
    • (2001) Cancer Res , vol.61 , pp. 2124-2128
    • Alonso, M.1    Hamelin, R.2    Kim, M.3
  • 37
    • 4444339673 scopus 로고    scopus 로고
    • Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme
    • Martinez R, Schackert HK, Plaschke J, Baretton G, Appelt H, Schackert G. Molecular mechanisms associated with chromosomal and microsatellite instability in sporadic glioblastoma multiforme. Oncology 2004; 66:395-403.
    • (2004) Oncology , vol.66 , pp. 395-403
    • Martinez, R.1    Schackert, H.K.2    Plaschke, J.3    Baretton, G.4    Appelt, H.5    Schackert, G.6


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