A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers

Molecular Carcinogenesis

Volumn 24, Issue 2, 1999, Pages 90-98

  Herfarth, Klaus K F ^a   Brent, Thomas P ^b   Danam, Rebecca P ^b   Remack, Joanna S ^b   Kodner, Ira J ^a   Wells Jr , Samuel A ^a   Goodfellow, Paul J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Colorectal neoplasm; DNA methylation; Gene expression; Methylguanine; O6 methylguanine DNA methyltransferase

Indexed keywords

DNA METHYLTRANSFERASE; METHYLGUANIDINE;

ARTICLE; COLON BIOPSY; COLON MUCOSA; COLORECTAL CANCER; DNA METHYLATION; DNA SEQUENCE; DRUG SENSITIVITY; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; PRIORITY JOURNAL; PROMOTER REGION; SOUTHERN BLOTTING;

COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; PROMOTER REGIONS (GENETICS);

EID: 0032969319     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199902)24:2<90::AID-MC3>3.0.CO;2-B     Document Type: Article

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