Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU

Blood

Volumn 88, Issue 5, 1996, Pages 1649-1655

  Gerson, Stanton L ^a   Phillips, Weldon ^b   Kastan, Michael ^b   Dumenco, Luba L ^b   Donovan, Cheryl ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

6 O ALKYLGUANINE DNA ALKYLTRANSFERASE; 6 O ALKYLGUANINE DNA ALKYLTRANSFERASE INHIBITOR; 6 O BENZYLGUANINE; CARMUSTINE; CD34 ANTIGEN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; NITROSOUREA DERIVATIVE; STEM CELL FACTOR;

ARTICLE; BONE MARROW CELL; BONE MARROW SUPPRESSION; CELL TYPE; COLONY FORMING CELL; CONTROLLED STUDY; CYTOTOXICITY; DNA REPAIR; DOSE RESPONSE; DRUG MIXTURE; ENZYME ACTIVITY; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA; MONONUCLEAR CELL; PRIORITY JOURNAL;

EID: 0029794643     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.5.1649.bloodjournal8851649     Document Type: Article

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