메뉴 건너뛰기




Volumn 11, Issue 2, 2011, Pages 337-367

Nano/microscale technologies for drug delivery

Author keywords

drug delivery; in vitro test; in vivo test; microtechnology; Nanotechnology

Indexed keywords


EID: 79960354273     PISSN: 02195194     EISSN: None     Source Type: Journal    
DOI: 10.1142/S021951941100406X     Document Type: Review
Times cited : (13)

References (161)
  • 1
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • DOI 10.1126/science.1095833
    • Allen TM, Cullis PR, Drug delivery systems: Entering the mainstream, Science 303:1818-1822, 2004. (Pubitemid 38374867)
    • (2004) Science , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 2
    • 0141765877 scopus 로고    scopus 로고
    • Small-scale systems for in vivo drug delivery
    • DOI 10.1038/nbt876
    • LaVan DA, McGuire T, Langer R, Small-scale systems for in vivo drug delivery, Nat Biotechnol 21:1184-1191, 2003. (Pubitemid 37186175)
    • (2003) Nature Biotechnology , vol.21 , Issue.10 , pp. 1184-1191
    • LaVan, D.A.1    McGuire, T.2    Langer, R.3
  • 3
    • 71549141624 scopus 로고    scopus 로고
    • Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems
    • Caldorera-Moore M, Peppas NA, Micro- and nanotechnologies for intelligent and responsive biomaterial-based medical systems, Adv Drug Deliv Rev 61:1391-1401, 2009.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 1391-1401
    • Caldorera-Moore, M.1    Peppas, N.A.2
  • 5
    • 37649010665 scopus 로고    scopus 로고
    • Microfluidics for drug discovery and development: From target selection to product lifecycle management
    • Kang L, Chung BG, Langer R, Khademhosseini A, Microfluidics for drug discovery and development: From target selection to product lifecycle management, Drug Discov Today 13:1-13, 2008.
    • (2008) Drug Discov Today , vol.13 , pp. 1-13
    • Kang, L.1    Chung, B.G.2    Langer, R.3    Khademhosseini, A.4
  • 6
    • 37349009261 scopus 로고    scopus 로고
    • Micro- and nanoscale technologies for tissue engineering and drug discovery applications
    • DOI 10.1517/17460441.2.12.1653
    • Chung BG, Kang L, Khademhosseini A, Micro- and nanoscale technologies for tissue engineering and drug discovery applications, Expert Opin Drug Discov 2:1653-1668, 2007. (Pubitemid 350285352)
    • (2007) Expert Opinion on Drug Discovery , vol.2 , Issue.12 , pp. 1653-1668
    • Chung, B.G.1    Kang, L.2    Khademhosseini, A.3
  • 7
    • 1142305959 scopus 로고    scopus 로고
    • Development of a Microscale Cell Culture Analog to Probe Naphthalene Toxicity
    • DOI 10.1021/bp0341996
    • Viravaidya K, Sin A, Shuler ML, Development of a microscale cell culture analog to probe naphthalene toxicity, Biotechnol Prog 20:316-323, 2004. (Pubitemid 38204204)
    • (2004) Biotechnology Progress , vol.20 , Issue.1 , pp. 316-323
    • Viravaidya, K.1    Sin, A.2    Shuler, M.L.3
  • 8
    • 72049119863 scopus 로고    scopus 로고
    • Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments
    • Zhang C, Zhao Z, Abdul Rahim NA, van Noort D, Yu H, Towards a human-on-chip: Culturing multiple cell types on a chip with compartmentalized microenvironments, Lab Chip 9:3185-3192, 2009.
    • (2009) Lab Chip , vol.9 , pp. 3185-3192
    • Zhang, C.1    Zhao, Z.2    Abdul Rahim, N.A.3    Van Noort, D.4    Yu, H.5
  • 9
    • 20444375525 scopus 로고    scopus 로고
    • The human epidermis models EpiSkin®, SkinEthic® and EpiDerm®: An evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport
    • DOI 10.1016/j.ejpb.2005.03.004, PII S0939641105001116
    • Netzlaff F, Lehr CM, Wertz PW, Schaefer UF, The human epidermis models EpiSkin ®, SkinEthic ® and EpiDerm ®: An evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport, Eur J Pharm Biopharm 60:167-178, 2005. (Pubitemid 40804559)
    • (2005) European Journal of Pharmaceutics and Biopharmaceutics , vol.60 , Issue.2 , pp. 167-178
    • Netzlaff, F.1    Lehr, C.-M.2    Wertz, P.W.3    Schaefer, U.F.4
  • 10
    • 79960382978 scopus 로고    scopus 로고
    • Micro/nano-fabrication technologies for cell biology, to appear in Med Biol Eng Comput. 11. Khamsi R, Labs on a chip: Meet the stripped down rat
    • Qian T, Wang Y, Micro/nano-fabrication technologies for cell biology, to appear in Med Biol Eng Comput.
    • (2005) Nature , vol.435 , pp. 12-13
    • Qian, T.1    Wang, Y.2
  • 11
    • 18344372247 scopus 로고    scopus 로고
    • Labs on a chip: Meet the stripped down rat
    • DOI 10.1038/435012a
    • Khamsi R, Labs on a chip: Meet the stripped down rat, Nature 435:12-13, 2005. (Pubitemid 40655889)
    • (2005) Nature , vol.435 , Issue.7038 , pp. 12-13
    • Khamsi, R.1
  • 12
    • 63749111006 scopus 로고    scopus 로고
    • Micro- and nanobiosensors-state of the art and trends
    • Urban GA, Micro- and nanobiosensors-state of the art and trends, Meas Sci Technol 20:1-18, 2009.
    • (2009) Meas Sci Technol , vol.20 , pp. 1-18
    • Urban, G.A.1
  • 13
    • 34249910894 scopus 로고    scopus 로고
    • Nanotechnology: What it can do for drug delivery
    • DOI 10.1016/j.jconrel.2007.05.003, PII S0168365907002143
    • Park K, Nanotechnology: What it can do for drug delivery, J Control Release 120: 1-3, 2007. (Pubitemid 46874626)
    • (2007) Journal of Controlled Release , vol.120 , Issue.1-2 , pp. 1-3
    • Park, K.1
  • 15
    • 34547178393 scopus 로고    scopus 로고
    • Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers
    • DOI 10.1016/j.jconrel.2007.03.022, PII S0168365907001769
    • Champion JA, Katare YK, Mitragotri S, Particle shape: A new design parameter for micro- and nanoscale drug delivery carriers, J Control Release 121:3-9, 2007. (Pubitemid 47126059)
    • (2007) Journal of Controlled Release , vol.121 , Issue.1-2 , pp. 3-9
    • Champion, J.A.1    Katare, Y.K.2    Mitragotri, S.3
  • 16
    • 34248402413 scopus 로고    scopus 로고
    • Shape effects of filaments versus spherical particles in flow and drug delivery
    • DOI 10.1038/nnano.2007.70, PII NNANO200770
    • Geng Y, Dalhaimer P, Cai S, Tsai R, Tewari M, Minko T, Discher DE, Shape effects of filaments versus spherical particles in flow and drug delivery, Nat Nanotechnol 2:249-255, 2007. (Pubitemid 46739812)
    • (2007) Nature Nanotechnology , vol.2 , Issue.4 , pp. 249-255
    • Geng, Y.1    Dalhaimer, P.2    Cai, S.3    Tsai, R.4    Tewari, M.5    Minko, T.6    Discher, D.E.7
  • 17
    • 34248360301 scopus 로고    scopus 로고
    • Nanomedicine: Nanocarriers shape up for long life
    • DOI 10.1038/nnano.2007.88, PII NNANO200788
    • Nishiyama N, Nanomedicine: Nanocarriers shape up for long life, Nat Nanotechnol 2:203-204, 2007. (Pubitemid 46739817)
    • (2007) Nature Nanotechnology , vol.2 , Issue.4 , pp. 203-204
    • Nishiyama, N.1
  • 18
    • 0037462997 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug and gene delivery to cells and tissue
    • DOI 10.1016/S0169-409X(02)00228-4
    • Panyam J, Labhasetwar V, Biodegradable nanoparticles for drug and gene delivery to cells and tissue, Adv Drug Deliv Rev 55:329-347, 2003. (Pubitemid 36297053)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.3 , pp. 329-347
    • Panyam, J.1    Labhasetwar, V.2
  • 21
    • 42149136753 scopus 로고    scopus 로고
    • Reductively labile PRINT particles for the delivery of doxorubicin to HeLa cells
    • DOI 10.1021/ja801436j
    • Petros RA, Ropp PA, DeSimone JM, Reductively labile PRINT particles for the delivery of doxorubicin to HeLa cells, J Am Chem Soc 130:5008-5009, 2008. (Pubitemid 351537040)
    • (2008) Journal of the American Chemical Society , vol.130 , Issue.15 , pp. 5008-5009
    • Petras, R.A.1    Ropp, P.A.2    DeSimone, J.M.3
  • 22
    • 38349144057 scopus 로고    scopus 로고
    • Nanoimprint lithography based fabrication of shape-specific, enzymatically-triggered smart nanoparticles
    • Glangchai LC, Caldorera-Moore M, Shi L, Roy K, Nanoimprint lithography based fabrication of shape-specific, enzymatically-triggered smart nanoparticles, J Control Release 125:263-272, 2008.
    • (2008) J Control Release , vol.125 , pp. 263-272
    • Glangchai, L.C.1    Caldorera-Moore, M.2    Shi, L.3    Roy, K.4
  • 24
    • 77952374647 scopus 로고    scopus 로고
    • Engineering nanoscopic hydrogels via photo-crosslinking salt-induced polymer assembly for targeted drug delivery
    • Wang YC, Wu J, Li Y, Du JZ, Yuan YY, Wang J, Engineering nanoscopic hydrogels via photo-crosslinking salt-induced polymer assembly for targeted drug delivery, Chem Commun (Camb) 46:3520-3522, 2010.
    • (2010) Chem Commun (Camb) , vol.46 , pp. 3520-3522
    • Wang, Y.C.1    Wu, J.2    Li, Y.3    Du, J.Z.4    Yuan, Y.Y.5    Wang, J.6
  • 25
    • 34548621494 scopus 로고    scopus 로고
    • Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices
    • Betancourt T, Brannon-Peppas L, Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices, Int J Nanomedicine 1:483-495, 2006.
    • (2006) Int J Nanomedicine , vol.1 , pp. 483-495
    • Betancourt, T.1    Brannon-Peppas, L.2
  • 26
    • 1842376840 scopus 로고    scopus 로고
    • A porous silicon-based optical interferometric biosensor
    • DOI 10.1126/science.278.5339.840
    • Lin VS, Motesharei K, Dancil KP, Sailor MJ, Ghadiri MR, A porous silicon-based optical interferometric biosensor, Science 278:840-843, 1997. (Pubitemid 27467917)
    • (1997) Science , vol.278 , Issue.5339 , pp. 840-843
    • Lin, V.S.-Y.1    Motesharei, K.2    Dancil, K.-P.S.3    Sailor, M.J.4    Ghadiri, M.R.5
  • 27
    • 0037470986 scopus 로고    scopus 로고
    • Polymer replicas of photonic porous silicon for sensing and drug delivery applications
    • DOI 10.1126/science.1081298
    • Li YY, Cunin F, Link JR, Gao T, Betts RE, Reiver SH, Chin V, Bhatia SN, Sailor MJ, Polymer replicas of photonic porous silicon for sensing and drug delivery applications, Science 299:2045-2047, 2003. (Pubitemid 36383727)
    • (2003) Science , vol.299 , Issue.5615 , pp. 2045-2047
    • Li, Y.Y.1    Cunin, F.2    Link, J.R.3    Gao, T.4    Betts, R.E.5    Reiver, S.H.6    Chin, V.7    Bhatia, S.N.8    Sailor, M.J.9
  • 28
    • 51849106535 scopus 로고    scopus 로고
    • ZnO-based hollow nanoparticles by selective etching: Elimination and reconstruction of metalsemiconductor interface, improvement of blue emission and photocatalysis
    • Zeng H, Cai W, Liu P, Xu X, Zhou H, Klingshirn C, Kalt H, ZnO-based hollow nanoparticles by selective etching: Elimination and reconstruction of metalsemiconductor interface, improvement of blue emission and photocatalysis, ACS Nano 2:1661-1670, 2008.
    • (2008) ACS Nano , vol.2 , pp. 1661-1670
    • Zeng, H.1    Cai, W.2    Liu, P.3    Xu, X.4    Zhou, H.5    Klingshirn, C.6    Kalt, H.7
  • 31
    • 75749134537 scopus 로고    scopus 로고
    • Hollow/rattletype mesoporous nanostructures by a structural difference-based selective etching strategy
    • Chen Y, Chen H, Guo L, He Q, Chen F, Zhou J, Feng J, Shi J, Hollow/rattletype mesoporous nanostructures by a structural difference-based selective etching strategy, ACS Nano 4:529-539, 2010.
    • (2010) ACS Nano , vol.4 , pp. 529-539
    • Chen, Y.1    Chen, H.2    Guo, L.3    He, Q.4    Chen, F.5    Zhou, J.6    Feng, J.7    Shi, J.8
  • 32
    • 0030848621 scopus 로고    scopus 로고
    • Fuzzy nanoassemblies: Toward layered polymeric multicomposites
    • DOI 10.1126/science.277.5330.1232
    • Decher G, Fuzzy nanoassemblies: Toward layered polymeric multicomposites, Science 277:1232-1237, 1997. (Pubitemid 27449063)
    • (1997) Science , vol.277 , Issue.5330 , pp. 1232-1237
    • Decher, G.1
  • 34
    • 69749093489 scopus 로고    scopus 로고
    • Nanomembrane-driven co-elution and integration of active chemotherapeutic and anti-inflammatory agents
    • Pierstorff E, Ho D, Nanomembrane-driven co-elution and integration of active chemotherapeutic and anti-inflammatory agents, Int J Nanomedicine 3:425-433, 2008.
    • (2008) Int J Nanomedicine , vol.3 , pp. 425-433
    • Pierstorff, E.1    Ho, D.2
  • 35
    • 49749105600 scopus 로고    scopus 로고
    • Layer-by-layer assembled thin films composed of carboxyl-terminated poly(amidoamine) dendrimer as a pH-sensitive nano-device
    • Tomita S, Sato K, Anzai JI, Layer-by-layer assembled thin films composed of carboxyl-terminated poly(amidoamine) dendrimer as a pH-sensitive nano-device, J Colloid Interface Sci 326:35-40, 2008.
    • (2008) J Colloid Interface Sci , vol.326 , pp. 35-40
    • Tomita, S.1    Sato, K.2    Anzai, J.I.3
  • 40
    • 76749103259 scopus 로고    scopus 로고
    • Luttge R Winnubst LAJA Gardeniers HJGE Jansen JA The influence of nanoscale grooved substrates on osteoblast behavior and extracellular matrix deposition
    • Lamers E, Frank Walboomers X, Domanski M, te Riet J, van Delft FCMJM, Luttge R, Winnubst LAJA, Gardeniers HJGE, Jansen JA, The influence of nanoscale grooved substrates on osteoblast behavior and extracellular matrix deposition, Biomaterials 31:3307-3316, 2010.
    • (2010) Biomaterials , vol.31 , pp. 3307-3316
    • Lamers, E.1    Frank Walboomers, X.2    Domanski, M.3    Te Riet, J.4    Van Delft, F.C.M.J.M.5
  • 41
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • DOI 10.1038/nrm2236, PII NRM2236
    • Pampaloni F, Reynaud EG, Stelzer EHK, The third dimension bridges the gap between cell culture and live tissue, Nat Rev Mol Cell Biol 8:839-845, 2007. (Pubitemid 47462131)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.10 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.K.3
  • 42
    • 67650485298 scopus 로고    scopus 로고
    • Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip
    • Lee KH, Kwon GH, Shin SJ, Baek JY, Han DK, Park Y, Lee SH, Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip, J Biomed Mater Res A 90:619-628, 2009.
    • (2009) J Biomed Mater Res A , vol.90 , pp. 619-628
    • Lee, K.H.1    Kwon, G.H.2    Shin, S.J.3    Baek, J.Y.4    Han, D.K.5    Park, Y.6    Lee, S.H.7
  • 45
    • 65249178345 scopus 로고    scopus 로고
    • Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery
    • Liu Z, Tabakman S, Welsher K, Dai H, Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery, Nano Res 2:85-120, 2009.
    • (2009) Nano Res , vol.2 , pp. 85-120
    • Liu, Z.1    Tabakman, S.2    Welsher, K.3    Dai, H.4
  • 47
    • 77953396614 scopus 로고    scopus 로고
    • Single walled carbon nanotubes as reporters for the optical detection of glucose
    • Barone PW, Strano MS, Single walled carbon nanotubes as reporters for the optical detection of glucose, J Diabetes Sci Technol 3:242-252, 2009.
    • (2009) J Diabetes Sci Technol , vol.3 , pp. 242-252
    • Barone, P.W.1    Strano, M.S.2
  • 48
    • 11144314296 scopus 로고    scopus 로고
    • Near-infrared optical sensors based on single-walled carbon nanotubes
    • DOI 10.1038/nmat1276
    • Barone PW, Baik S, Heller DA, Strano MS, Near-infrared optical sensors based on single-walled carbon nanotubes, Nat Mater 4:86-92, 2005. (Pubitemid 40021007)
    • (2005) Nature Materials , vol.4 , Issue.1 , pp. 86-92
    • Barone, P.W.1    Baik, S.2    Heller, D.A.3    Strano, M.S.4
  • 49
    • 33845746385 scopus 로고    scopus 로고
    • Reversible control of carbon nanotube aggregation for a glucose affinity sensor
    • DOI 10.1002/anie.200603138
    • Barone PW, Strano MS, Reversible control of carbon nanotube aggregation for a glucose affinity sensor, Angew Chem Int Ed Engl 45:8138-8141, 2006. (Pubitemid 44974146)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.48 , pp. 8138-8141
    • Barone, P.W.1    Strano, M.S.2
  • 51
    • 33645381269 scopus 로고    scopus 로고
    • Detection of DNA hybridization using the near-infrared band-gap fluorescence of single-walled carbon nanotubes
    • Jeng ES, Moll AE, Roy AC, Gastala JB, Strano MS, Detection of DNA hybridization using the near-infrared band-gap fluorescence of single-walled carbon nanotubes, Nano Lett 6:371-375, 2006.
    • (2006) Nano Lett , vol.6 , pp. 371-375
    • Jeng, E.S.1    Moll, A.E.2    Roy, A.C.3    Gastala, J.B.4    Strano, M.S.5
  • 53
    • 47949124661 scopus 로고    scopus 로고
    • Electrode chemistry yields a nanoparticlebased NMR sensor for calcium
    • Taktak S, Weissleder R, Josephson L, Electrode chemistry yields a nanoparticlebased NMR sensor for calcium, Langmuir 24:7596-7598, 2008.
    • (2008) Langmuir , vol.24 , pp. 7596-7598
    • Taktak, S.1    Weissleder, R.2    Josephson, L.3
  • 55
    • 57749194879 scopus 로고    scopus 로고
    • Gold nanoparticles integrated in a nanotube array for electrochemical detection of glucose
    • Zhou YG, Yang S, Qian QY, Xia XH, Gold nanoparticles integrated in a nanotube array for electrochemical detection of glucose, Electrochem Commun 11:216-219, 2009.
    • (2009) Electrochem Commun , vol.11 , pp. 216-219
    • Zhou, Y.G.1    Yang, S.2    Qian, Q.Y.3    Xia, X.H.4
  • 56
    • 77950389176 scopus 로고    scopus 로고
    • Nanofluidic technology for biomolecule applications: A critical review
    • Napoli M, Eijkel JC, Pennathur S, Nanofluidic technology for biomolecule applications: A critical review, Lab Chip 10:957-985, 2010.
    • (2010) Lab Chip , vol.10 , pp. 957-985
    • Napoli, M.1    Eijkel, J.C.2    Pennathur, S.3
  • 57
    • 77952524607 scopus 로고    scopus 로고
    • Nanopillar, nanoball, and nanofibers for highly efficient analysis of biomolecules
    • Kaji N, Okamoto Y, Tokeshi M, Baba Y, Nanopillar, nanoball, and nanofibers for highly efficient analysis of biomolecules, Chem Soc Rev 39:948-956, 2010.
    • (2010) Chem Soc Rev , vol.39 , pp. 948-956
    • Kaji, N.1    Okamoto, Y.2    Tokeshi, M.3    Baba, Y.4
  • 59
    • 33846862689 scopus 로고    scopus 로고
    • A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins
    • DOI 10.1038/nnano.2006.206
    • Fu J, Schoch RB, Stevens AL, Tannenbaum SR, Han J, A patterned anisotropic nanofluidic sieving structure for continuous-flow separation of DNA and proteins, Nat Nanotechnol 2:121-128, 2007. (Pubitemid 46226372)
    • (2007) Nature Nanotechnology , vol.2 , Issue.2 , pp. 121-128
    • Fu, J.1    Schoch, R.B.2    Stevens, A.L.3    Tannenbaum, S.R.4    Han, J.5
  • 60
    • 33947392596 scopus 로고    scopus 로고
    • Self-assembled colloidal arrays as three-dimensional nanofluidic sieves for separation of biomolecules on microchips
    • DOI 10.1021/ac061931h
    • Zeng Y, Harrison DJ, Self-assembled colloidal arrays as three-dimensional nanofluidic sieves for separation of biomolecules on microchips, Anal Chem 79:2289-2295, 2007. (Pubitemid 46449007)
    • (2007) Analytical Chemistry , vol.79 , Issue.6 , pp. 2289-2295
    • Zeng, Y.1    Harrison, D.J.2
  • 61
    • 47949121194 scopus 로고    scopus 로고
    • Nanofluidic concentration of selectively extracted biomolecule analytes by microtubules
    • Kim T, Meyhofer E, Nanofluidic concentration of selectively extracted biomolecule analytes by microtubules, Anal Chem 80:5383-5390, 2008.
    • (2008) Anal Chem , vol.80 , pp. 5383-5390
    • Kim, T.1    Meyhofer, E.2
  • 62
    • 77951974200 scopus 로고    scopus 로고
    • Surface functionalization of polyketal microparticles with nitrilotriacetic acid-nickel complexes for efficient protein capture and delivery
    • Sy JC, Phelps EA, Garcia AJ, Murthy N, Davis ME, Surface functionalization of polyketal microparticles with nitrilotriacetic acid-nickel complexes for efficient protein capture and delivery, Biomaterials 31:4987-4994, 2010.
    • (2010) Biomaterials , vol.31 , pp. 4987-4994
    • Sy, J.C.1    Phelps, E.A.2    Garcia, A.J.3    Murthy, N.4    Davis, M.E.5
  • 63
    • 77952468428 scopus 로고    scopus 로고
    • One-step fabrication of triple-layered polymeric microparticles with layer localization of drugs as a novel drug-delivery system
    • Lee WL, Widjaja E, Loo SCJ, One-step fabrication of triple-layered polymeric microparticles with layer localization of drugs as a novel drug-delivery system, Small 6:1003-1011, 2010.
    • (2010) Small , vol.6 , pp. 1003-1011
    • Lee, W.L.1    Widjaja, E.2    Loo, S.C.J.3
  • 65
    • 0037124471 scopus 로고    scopus 로고
    • Bioadhesive microdevices with multiple reservoirs: A new platform for oral drug delivery
    • DOI 10.1016/S0168-3659(02)00074-3, PII S0168365902000743
    • Ahmed A, Bonner C, Desai TA, Bioadhesive microdevices with multiple reservoirs: A new platform for oral drug delivery, J Control Release 81:291-306, 2002. (Pubitemid 34607149)
    • (2002) Journal of Controlled Release , vol.81 , Issue.3 , pp. 291-306
    • Ahmed, A.1    Bonner, C.2    Desai, T.A.3
  • 66
    • 0037462995 scopus 로고    scopus 로고
    • Microfabricated drug delivery systems: From particles to pores
    • DOI 10.1016/S0169-409X(02)00227-2
    • Tao SL, Desai TA, Microfabricated drug delivery systems: from particles to pores, Adv Drug Deliv Rev 55:315-328, 2003. (Pubitemid 36293790)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.3 , pp. 315-328
    • Tao, S.L.1    Desai, T.A.2
  • 67
    • 72849125184 scopus 로고    scopus 로고
    • Microfabricated devices for enhanced bioadhesive drug delivery: Attachment to and smallmolecule release through a cell monolayer under flow
    • Ainslie KM, Lowe RD, Beaudette TT, Petty L, Bachelder EM, Desai TA, Microfabricated devices for enhanced bioadhesive drug delivery: Attachment to and smallmolecule release through a cell monolayer under flow, Small 5:2857-2863, 2009.
    • (2009) Small , vol.5 , pp. 2857-2863
    • Ainslie, K.M.1    Lowe, R.D.2    Beaudette, T.T.3    Petty, L.4    Bachelder, E.M.5    Desai, T.A.6
  • 68
    • 0037436923 scopus 로고    scopus 로고
    • Bioadhesive microspheres as a controlled drug delivery system
    • DOI 10.1016/S0378-5173(03)00087-5
    • Vasir JK, Tambwekar K, Garg S, Bioadhesive microspheres as a controlled drug delivery system, Int J Pharm 255:13-32, 2003. (Pubitemid 36369587)
    • (2003) International Journal of Pharmaceutics , vol.255 , Issue.1-2 , pp. 13-32
    • Vasir, J.K.1    Tambwekar, K.2    Garg, S.3
  • 69
    • 70849124071 scopus 로고    scopus 로고
    • Oral delivery of low molecular weight heparin microspheres prepared using biodegradable polymer matrix system
    • Lanke SSS, Gayakwad SG, Strom JG, D'Souza MJ, Oral delivery of low molecular weight heparin microspheres prepared using biodegradable polymer matrix system, J Microencapsul 26:493-500, 2009.
    • (2009) J Microencapsul , vol.26 , pp. 493-500
    • Lanke, S.S.S.1    Gayakwad, S.G.2    Strom, J.G.3    D'Souza, M.J.4
  • 70
    • 77149137068 scopus 로고    scopus 로고
    • Manipulation of process parameters to achieve different ternary phase microparticle configurations
    • LeeWL, FooWL, Widjaja E, Loo SC, Manipulation of process parameters to achieve different ternary phase microparticle configurations, Acta Biomater 6:1342-1352, 2010.
    • (2010) Acta Biomater , vol.6 , pp. 1342-1352
    • Lee, W.L.1    Foo, W.L.2    Widjaja, E.3    Loo, S.C.4
  • 71
  • 72
    • 77952782180 scopus 로고    scopus 로고
    • Preparation of biodegradable liquid core PLLA microcapsules and hollow PLLA microcapsules using microfluidics
    • Lensen D, van Breukelen K, Vriezema DM, van Hest JC, Preparation of biodegradable liquid core PLLA microcapsules and hollow PLLA microcapsules using microfluidics, Macromol Biosci 10:475-480, 2010.
    • (2010) Macromol Biosci , vol.10 , pp. 475-480
    • Lensen, D.1    Van Breukelen, K.2    Vriezema, D.M.3    Van Hest, J.C.4
  • 73
    • 77954561647 scopus 로고    scopus 로고
    • Controlled self-assembly of monodisperse niosomes by microfluidic hydrodynamic focusing
    • Lo CT, Jahn A, Locascio LE, Vreeland WN, Controlled self-assembly of monodisperse niosomes by microfluidic hydrodynamic focusing, Langmuir 26:8559-8566, 2010.
    • (2010) Langmuir , vol.26 , pp. 8559-8566
    • Lo, C.T.1    Jahn, A.2    Locascio, L.E.3    Vreeland, W.N.4
  • 74
    • 77951688243 scopus 로고    scopus 로고
    • Preparation of monodisperse block copolymer vesicles via flow focusing in microfluidics
    • Thiele J, Steinhauser D, Pfohl T, Forster S, Preparation of monodisperse block copolymer vesicles via flow focusing in microfluidics, Langmuir 26:6860-6863, 2010.
    • (2010) Langmuir , vol.26 , pp. 6860-6863
    • Thiele, J.1    Steinhauser, D.2    Pfohl, T.3    Forster, S.4
  • 75
    • 67749133574 scopus 로고    scopus 로고
    • Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery
    • Xu Q, Hashimoto M, Dang TT, Hoare T, Kohane DS, Whitesides GM, Langer R, Anderson DG, Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery, Small 5:1575-1581, 2009.
    • (2009) Small , vol.5 , pp. 1575-1581
    • Xu, Q.1    Hashimoto, M.2    Dang, T.T.3    Hoare, T.4    Kohane, D.S.5    Whitesides, G.M.6    Langer, R.7    Anderson, D.G.8
  • 76
    • 77950152455 scopus 로고    scopus 로고
    • Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing
    • Valencia PM, Basto PA, Zhang L, Rhee M, Langer R, Farokhzad OC, Karnik R, Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing, ACS Nano 4:1671-1679, 2010.
    • (2010) ACS Nano , vol.4 , pp. 1671-1679
    • Valencia, P.M.1    Basto, P.A.2    Zhang, L.3    Rhee, M.4    Langer, R.5    Farokhzad, O.C.6    Karnik, R.7
  • 77
    • 77950133003 scopus 로고    scopus 로고
    • Generation of monodisperse silk microspheres prepared with microfluidics
    • Breslauer DN, Muller SJ, Lee LP, Generation of monodisperse silk microspheres prepared with microfluidics, Biomacromolecules 11:643-647, 2010.
    • (2010) Biomacromolecules , vol.11 , pp. 643-647
    • Breslauer, D.N.1    Muller, S.J.2    Lee, L.P.3
  • 79
    • 1542347972 scopus 로고    scopus 로고
    • Controlled vesicle self-assembly in microfluidic channels with hydrodynamic focusing
    • DOI 10.1021/ja0318030
    • Jahn A, Vreeland WN, Gaitan M, Locascio LE, Controlled vesicle self-assembly in microfluidic channels with hydrodynamic focusing, J Am Chem Soc 126:2674-2675, 2004. (Pubitemid 38314254)
    • (2004) Journal of the American Chemical Society , vol.126 , Issue.9 , pp. 2674-2675
    • Jahn, A.1    Vreeland, W.N.2    Gaitan, M.3    Locascio, L.E.4
  • 80
    • 34249977091 scopus 로고    scopus 로고
    • Microfluidic directed formation of liposomes of controlled size
    • DOI 10.1021/la070051a
    • Jahn A, Vreeland WN, DeVoe DL, Locascio LE, Gaitan M, Microfluidic directed formation of liposomes of controlled size, Langmuir 23:6289-6293, 2007. (Pubitemid 46880969)
    • (2007) Langmuir , vol.23 , Issue.11 , pp. 6289-6293
    • Jahn, A.1    Vreeland, W.N.2    Devoe, D.L.3    Locascio, L.E.4    Gaitan, M.5
  • 84
    • 0032841637 scopus 로고    scopus 로고
    • Microfabricated microneedles: A novel approach to transdermal drug delivery
    • Henry S, McAllister DV, Allen MG, Prausnitz MR, Microfabricated microneedles: A novel approach to transdermal drug delivery, J Pharm Sci 88:948, 1999.
    • (1999) J Pharm Sci , vol.88 , pp. 948
    • Henry, S.1    McAllister, D.V.2    Allen, M.G.3    Prausnitz, M.R.4
  • 86
    • 22144493011 scopus 로고    scopus 로고
    • Process optimization and characterization of silicon microneedles fabricated by wet etch technology
    • DOI 10.1016/j.mejo.2005.04.044, PII S0026269205001825
    • Wilke N, Mulcahy A, Ye SR, Morrissey A, Process optimization and characterization of silicon microneedles fabricated by wet etch technology, Microelectronics J 36:650-656, 2005. (Pubitemid 40973306)
    • (2005) Microelectronics Journal , vol.36 , Issue.7 , pp. 650-656
    • Wilke, N.1    Mulcahy, A.2    Ye, S.-R.3    Morrissey, A.4
  • 87
    • 77349091986 scopus 로고    scopus 로고
    • Super-short solid silicon microneedles for transdermal drug delivery applications
    • Li WZ, Huo MR, Zhou JP, Zhou YQ, Hao BH, Liu T, Zhang Y, Super-short solid silicon microneedles for transdermal drug delivery applications, Int J Pharm 389:122- 129, 2010.
    • (2010) Int J Pharm , vol.389 , pp. 122-129
    • Li, W.Z.1    Huo, M.R.2    Zhou, J.P.3    Zhou, Y.Q.4    Hao, B.H.5    Liu, T.6    Zhang, Y.7
  • 88
    • 4544361572 scopus 로고    scopus 로고
    • Non-photolithographic pattern transfer for fabricating arrayed three-dimensional microstructures by chemical anisotropic etching
    • Shikida M, Odagaki M, Todoroki N, Ando M, Ishihara Y, Ando T, Sato K, Non-photolithographic pattern transfer for fabricating arrayed three-dimensional microstructures by chemical anisotropic etching, Sens Actuators A Phys 116:264-271, 2004.
    • (2004) Sens Actuators A Phys , vol.116 , pp. 264-271
    • Shikida, M.1    Odagaki, M.2    Todoroki, N.3    Ando, M.4    Ishihara, Y.5    Ando, T.6    Sato, K.7
  • 89
    • 33748783815 scopus 로고    scopus 로고
    • Fabrication of a hollow needle structure by dicing, wet etching and metal deposition
    • DOI 10.1088/0960-1317/16/10/041, PII S0960131706223891, 041
    • Shikida M, Hasada T, Sato K, Fabrication of a hollow needle structure by dicing, wet etching and metal deposition, J Micromech Microeng 16:2230-2239, 2006. (Pubitemid 44403676)
    • (2006) Journal of Micromechanics and Microengineering , vol.16 , Issue.10 , pp. 2230-2239
    • Shikida, M.1    Hasada, T.2    Sato, K.3
  • 90
    • 33846492454 scopus 로고    scopus 로고
    • Coated microneedles for transdermal delivery
    • DOI 10.1016/j.jconrel.2006.10.017, PII S0168365906005839
    • Gill HS, Prausnitz MR, Coated microneedles for transdermal delivery, J Control Release 117:227-237, 2007. (Pubitemid 46161873)
    • (2007) Journal of Controlled Release , vol.117 , Issue.2 , pp. 227-237
    • Gill, H.S.1    Prausnitz, M.R.2
  • 94
    • 41149125384 scopus 로고    scopus 로고
    • Nickel microneedles fabricated by sequential copper and nickel electroless plating and copper chemical wet etching
    • Jung PG, Lee TW, Oh DJ, Hwang SJ, Jung ID, Lee SM, Ko JS, Nickel microneedles fabricated by sequential copper and nickel electroless plating and copper chemical wet etching, Sensor Mater 20:45-53, 2008.
    • (2008) Sensor Mater , vol.20 , pp. 45-53
    • Jung, P.G.1    Lee, T.W.2    Oh, D.J.3    Hwang, S.J.4    Jung, I.D.5    Lee, S.M.6    Ko, J.S.7
  • 95
    • 43449101895 scopus 로고    scopus 로고
    • Pocketed microneedles for drug delivery to the skin
    • Gill HS, Prausnitz MR, Pocketed microneedles for drug delivery to the skin, J Phys Chem Solids 69:1537-1541, 2008.
    • (2008) J Phys Chem Solids , vol.69 , pp. 1537-1541
    • Gill, H.S.1    Prausnitz, M.R.2
  • 96
    • 54949120972 scopus 로고    scopus 로고
    • Minimally invasive protein delivery with rapidly dissolving polymer microneedles
    • Sullivan SP, Murthy N, Prausnitz MR, Minimally invasive protein delivery with rapidly dissolving polymer microneedles, Adv Mater 20:933-938, 2008.
    • (2008) Adv Mater , vol.20 , pp. 933-938
    • Sullivan, S.P.1    Murthy, N.2    Prausnitz, M.R.3
  • 97
    • 40049112272 scopus 로고    scopus 로고
    • Dissolving microneedles for transdermal drug delivery
    • Lee JW, Park JH, Prausnitz MR, Dissolving microneedles for transdermal drug delivery, Biomaterials 29:2113-2124, 2008.
    • (2008) Biomaterials , vol.29 , pp. 2113-2124
    • Lee, J.W.1    Park, J.H.2    Prausnitz, M.R.3
  • 98
    • 33646882359 scopus 로고    scopus 로고
    • Polymer microneedles for controlled-release drug delivery
    • DOI 10.1007/s11095-006-0028-9
    • Park JH, Allen MG, Prausnitz MR, Polymer microneedles for controlled-release drug delivery, Pharm Res 23:1008-1019, 2006. (Pubitemid 43781409)
    • (2006) Pharmaceutical Research , vol.23 , Issue.5 , pp. 1008-1019
    • Park, J.-H.1    Allen, M.G.2    Prausnitz, M.R.3
  • 99
    • 37349124148 scopus 로고    scopus 로고
    • Evaluation of self-dissolving needles containing low molecular weight heparin (LMWH) in rats
    • DOI 10.1016/j.ijpharm.2007.07.036, PII S0378517307006485
    • Ito Y, Murakami A, Maeda T, Sugioka N, Takada K, Evaluation of self-dissolving needles containing low molecular weight heparin (LMWH) in rats, Int J Pharm 349:124-129, 2008. (Pubitemid 350299697)
    • (2008) International Journal of Pharmaceutics , vol.349 , Issue.1-2 , pp. 124-129
    • Ito, Y.1    Murakami, A.2    Maeda, T.3    Sugioka, N.4    Takada, K.5
  • 100
    • 58949100880 scopus 로고    scopus 로고
    • In vitro transdermal delivery of therapeutic antibodies using maltose microneedles
    • Li GH, Badkar A, Nema S, Kolli CS, Banga AK, In vitro transdermal delivery of therapeutic antibodies using maltose microneedles, Int J Pharm 368:109-115, 2009.
    • (2009) Int J Pharm , vol.368 , pp. 109-115
    • Li, G.H.1    Badkar, A.2    Nema, S.3    Kolli, C.S.4    Banga, A.K.5
  • 103
    • 38049146196 scopus 로고    scopus 로고
    • Characterization of solid maltose microneedles and their use for transdermal delivery
    • Kolli CS, Banga AK, Characterization of solid maltose microneedles and their use for transdermal delivery, Pharm Res 25:104-113, 2008.
    • (2008) Pharm Res , vol.25 , pp. 104-113
    • Kolli, C.S.1    Banga, A.K.2
  • 104
    • 0033611506 scopus 로고    scopus 로고
    • A controlled-release microchip
    • DOI 10.1038/16898
    • Santini JT, Cima MJ, Langer R, A controlled-release microchip, Nature 397:335-338, 1999. (Pubitemid 29061643)
    • (1999) Nature , vol.397 , Issue.6717 , pp. 335-338
    • Santini Jr., J.T.1    Cima, M.J.2    Langer, R.3
  • 107
    • 70350344569 scopus 로고    scopus 로고
    • Magnetically triggered reversible controlled drug delivery from microfabricated polymeric multireservoir devices
    • Cai KY, Luo Z, Hu Y, Chen XY, Liao YJ, Yang L, Deng LH, Magnetically triggered reversible controlled drug delivery from microfabricated polymeric multireservoir devices, Adv Mater 21:4045-4049, 2009.
    • (2009) Adv Mater , vol.21 , pp. 4045-4049
    • Cai, K.Y.1    Luo, Z.2    Hu, Y.3    Chen, X.Y.4    Liao, Y.J.5    Yang, L.6    Deng, L.H.7
  • 108
    • 33847790928 scopus 로고    scopus 로고
    • The microfabricated electrokinetic pump: A potential promising drug delivery technique
    • DOI 10.1517/17425247.4.2.119
    • Chen L, Choo J, Yan B, The microfabricated electrokinetic pump: A potential promising drug delivery technique, Expert Opin Drug Deliv 4:119-129, 2007. (Pubitemid 46389911)
    • (2007) Expert Opinion on Drug Delivery , vol.4 , Issue.2 , pp. 119-129
    • Chen, L.1    Choo, J.2    Yan, B.3
  • 109
    • 62649153322 scopus 로고    scopus 로고
    • A fritless, EOF microchip pump for high pressure pumping of aqueous and organic solvents
    • Lu Q, Collins GE, A fritless, EOF microchip pump for high pressure pumping of aqueous and organic solvents, Lab Chip 9:954-960, 2009.
    • (2009) Lab Chip , vol.9 , pp. 954-960
    • Lu, Q.1    Collins, G.E.2
  • 113
    • 76849115212 scopus 로고    scopus 로고
    • In vitro microscale systems for systematic drug toxicity study
    • Sung JH, Shuler ML, In vitro microscale systems for systematic drug toxicity study, Bioprocess Biosyst Eng 33:5-19, 2010.
    • (2010) Bioprocess Biosyst Eng , vol.33 , pp. 5-19
    • Sung, J.H.1    Shuler, M.L.2
  • 115
    • 1842814047 scopus 로고    scopus 로고
    • Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies
    • DOI 10.1021/bp034238d
    • Viravaidya K, Shuler ML, Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies, Biotechnol Prog 20:590-597, 2004. (Pubitemid 38459166)
    • (2004) Biotechnology Progress , vol.20 , Issue.2 , pp. 590-597
    • Viravaidya, K.1    Shuler, M.L.2
  • 116
    • 37349027919 scopus 로고    scopus 로고
    • Biomolecular gradients in cell culture systems
    • Keenan TM, Folch A, Biomolecular gradients in cell culture systems, Lab Chip 8: 34-57, 2008.
    • (2008) Lab Chip , vol.8 , pp. 34-57
    • Keenan, T.M.1    Folch, A.2
  • 117
    • 84999274083 scopus 로고    scopus 로고
    • A microfluidic gradient maker for toxicity testing of bupivacaine and lidocaine
    • Tirella A, Marano M, Vozzi F, Ahluwalia A, A microfluidic gradient maker for toxicity testing of bupivacaine and lidocaine, Toxicol In Vitro 22:1957-1964, 2008.
    • (2008) Toxicol In Vitro , vol.22 , pp. 1957-1964
    • Tirella, A.1    Marano, M.2    Vozzi, F.3    Ahluwalia, A.4
  • 118
    • 0034899540 scopus 로고    scopus 로고
    • Finite element modelling and design of a concentration gradient generating bioreactor: Application to biological pattern formation and toxicology, to appear in Toxicol In Vitro. 119. Hodgson J, ADMET - turning chemicals into drugs
    • Vozzi G, Mazzei D, Tirella A, Vozzi F, Ahluwalia A, Finite element modelling and design of a concentration gradient generating bioreactor: Application to biological pattern formation and toxicology, to appear in Toxicol In Vitro.
    • (2001) Nat Biotechnol , vol.19 , pp. 722-726
    • Vozzi, G.1    Mazzei, D.2    Tirella, A.3    Vozzi, F.4    Ahluwalia, A.5
  • 119
    • 0034899540 scopus 로고    scopus 로고
    • ADMET - turning chemicals into drugs
    • Hodgson J, ADMET - turning chemicals into drugs, Nat Biotechnol 19:722-726, 2001.
    • (2001) Nat Biotechnol , vol.19 , pp. 722-726
    • Hodgson, J.1
  • 123
    • 56449113183 scopus 로고    scopus 로고
    • Microvalve-assisted patterning platform for measuring cellular dynamics based on 3D cell culture
    • Kim MS, Lee W, Kim YC, Park JK, Microvalve-assisted patterning platform for measuring cellular dynamics based on 3D cell culture, Biotechnol Bioeng 101:1005-1013, 2008.
    • (2008) Biotechnol Bioeng , vol.101 , pp. 1005-1013
    • Kim, M.S.1    Lee, W.2    Kim, Y.C.3    Park, J.K.4
  • 124
    • 33846032329 scopus 로고    scopus 로고
    • A microfluidic platform for 3-dimensional cell culture and cell-based assays
    • DOI 10.1007/s10544-006-9016-4
    • Kim MS, Yeon JH, Park JK, A microfluidic platform for 3-dimensional cell culture and cell-based assays, Biomed Microdevices 9:25-34, 2007. (Pubitemid 46050126)
    • (2007) Biomedical Microdevices , vol.9 , Issue.1 , pp. 25-34
    • Kim, M.S.1    Yeon, J.H.2    Park, J.-K.3
  • 127
    • 77956116033 scopus 로고    scopus 로고
    • Alginate-based microfluidic system for tumor spheroid formation and anticancer agent screening
    • Chen M, Gupta M, Cheung K, Alginate-based microfluidic system for tumor spheroid formation and anticancer agent screening, Biomed Microdevices 12:647-654, 2010.
    • (2010) Biomed Microdevices , vol.12 , pp. 647-654
    • Chen, M.1    Gupta, M.2    Cheung, K.3
  • 128
    • 67650481611 scopus 로고    scopus 로고
    • A microfluidic 3D hepatocyte chip for drug toxicity testing
    • Toh YC, Lim TC, Tai D, Xiao G, van Noort D, Yu H, A microfluidic 3D hepatocyte chip for drug toxicity testing, Lab Chip 9:2026-2035, 2009.
    • (2009) Lab Chip , vol.9 , pp. 2026-2035
    • Toh, Y.C.1    Lim, T.C.2    Tai, D.3    Xiao, G.4    Van Noort, D.5    Yu, H.6
  • 129
    • 33744947793 scopus 로고    scopus 로고
    • Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap
    • Ho CT, Lin RZ, Chang WY, Chang HY, Liu CH, Rapid heterogeneous liver-cell on-chip patterning via the enhanced field-induced dielectrophoresis trap, Lab Chip 6:724-734, 2006.
    • (2006) Lab Chip , vol.6 , pp. 724-734
    • Ho, C.T.1    Lin, R.Z.2    Chang, W.Y.3    Chang, H.Y.4    Liu, C.H.5
  • 130
    • 77951884924 scopus 로고    scopus 로고
    • A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells
    • Jang KJ, Suh KY, A multi-layer microfluidic device for efficient culture and analysis of renal tubular cells, Lab Chip 10:36-42, 2010.
    • (2010) Lab Chip , vol.10 , pp. 36-42
    • Jang, K.J.1    Suh, K.Y.2
  • 132
    • 54349116517 scopus 로고    scopus 로고
    • Development of a microfluidic device for the maintenance and interrogation of viable tissue biopsies
    • Hattersley SM, Dyer CE, Greenman J, Haswell SJ, Development of a microfluidic device for the maintenance and interrogation of viable tissue biopsies, Lab Chip 8:1842-1846, 2008.
    • (2008) Lab Chip , vol.8 , pp. 1842-1846
    • Hattersley, S.M.1    Dyer, C.E.2    Greenman, J.3    Haswell, S.J.4
  • 133
    • 73949083886 scopus 로고    scopus 로고
    • Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies
    • van Midwoud PM, Groothuis GMM, Merema MT, Verpoorte E, Microfluidic biochip for the perifusion of precision-cut rat liver slices for metabolism and toxicology studies, Biotechnol Bioeng 105:184-194, 2010.
    • (2010) Biotechnol Bioeng , vol.105 , pp. 184-194
    • Van Midwoud, P.M.1    Groothuis, G.M.M.2    Merema, M.T.3    Verpoorte, E.4
  • 135
    • 75649102124 scopus 로고    scopus 로고
    • Mechanical dissociation of swine liver to produce organoid units for tissue engineering and in vitro disease modeling
    • Irani K, Pomerantseva I, Hart AR, Sundback CA, Neville CM, Vacanti JP, Mechanical dissociation of swine liver to produce organoid units for tissue engineering and in vitro disease modeling, Artifi Organs 34:75-78, 2010.
    • (2010) Artifi Organs , vol.34 , pp. 75-78
    • Irani, K.1    Pomerantseva, I.2    Hart, A.R.3    Sundback, C.A.4    Neville, C.M.5    Vacanti, J.P.6
  • 137
    • 64749086511 scopus 로고    scopus 로고
    • A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers
    • Tatosian DA, Shuler ML, A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers, Biotechnol Bioeng 103:187-198, 2009.
    • (2009) Biotechnol Bioeng , vol.103 , pp. 187-198
    • Tatosian, D.A.1    Shuler, M.L.2
  • 138
    • 65649133932 scopus 로고    scopus 로고
    • A micro cell culture analog (microCCA) with 3D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anticancer drugs
    • Sung JH, Shuler ML, A micro cell culture analog (microCCA) with 3D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anticancer drugs, Lab Chip 9:1385-1394, 2009.
    • (2009) Lab Chip , vol.9 , pp. 1385-1394
    • Sung, J.H.1    Shuler, M.L.2
  • 139
    • 69249095795 scopus 로고    scopus 로고
    • Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity
    • Mahler GJ, Esch MB, Glahn RP, Shuler ML, Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity, Biotechnol Bioeng 104:193-205, 2009.
    • (2009) Biotechnol Bioeng , vol.104 , pp. 193-205
    • Mahler, G.J.1    Esch, M.B.2    Glahn, R.P.3    Shuler, M.L.4
  • 140
    • 75749153235 scopus 로고    scopus 로고
    • A microfluidic device for a pharmacokineticpharmacodynamic (PK-PD) model on a chip
    • Sung JH, Kam C, Shuler ML, A microfluidic device for a pharmacokineticpharmacodynamic (PK-PD) model on a chip, Lab Chip 10:446-455, 2010.
    • (2010) Lab Chip , vol.10 , pp. 446-455
    • Sung, J.H.1    Kam, C.2    Shuler, M.L.3
  • 143
    • 72849136484 scopus 로고    scopus 로고
    • A blood sampling microsystem for pharmacokinetic applications: Design, fabrication, and initial results
    • Li T, Barnett A, Rogers KL, Gianchandani YB, A blood sampling microsystem for pharmacokinetic applications: Design, fabrication, and initial results, Lab Chip 9:3495-3503, 2009.
    • (2009) Lab Chip , vol.9 , pp. 3495-3503
    • Li, T.1    Barnett, A.2    Rogers, K.L.3    Gianchandani, Y.B.4
  • 144
    • 33747130046 scopus 로고    scopus 로고
    • A microfluidic fluorous solid-phase extraction chip for purification of amino acids
    • DOI 10.1016/j.jcis.2006.05.019, PII S0021979706004267
    • Hu G, Lee JSH, Li D, A microfluidic fluorous solid-phase extraction chip for purification of amino acids, J Colloid Interface Sci 301:697-702, 2006. (Pubitemid 44218991)
    • (2006) Journal of Colloid and Interface Science , vol.301 , Issue.2 , pp. 697-702
    • Hu, G.1    Lee, J.S.H.2    Li, D.3
  • 145
  • 146
    • 34748901143 scopus 로고    scopus 로고
    • Fully integrated microfluidic separations systems for biochemical analysis
    • DOI 10.1016/j.chroma.2007.06.010, PII S0021967307010217, Editors' Choice I
    • Roman GT, Kennedy RT, Fully integrated microfluidic separations systems for biochemical analysis, J Chromatogr A 1168:170-188; discussion 169, 2007. (Pubitemid 47488325)
    • (2007) Journal of Chromatography A , vol.1168 , Issue.1-2 , pp. 170-188
    • Roman, G.T.1    Kennedy, R.T.2
  • 147
    • 77951156095 scopus 로고    scopus 로고
    • Development of a PDMS-based microchip electrophoresis device for continuous online in vivo monitoring of microdialysis samples
    • Nandi P, Desaias DP, Lunte SM, Development of a PDMS-based microchip electrophoresis device for continuous online in vivo monitoring of microdialysis samples, Electrophoresis 31:1414-1422, 2010.
    • (2010) Electrophoresis , vol.31 , pp. 1414-1422
    • Nandi, P.1    Desaias, D.P.2    Lunte, S.M.3
  • 148
    • 77950998809 scopus 로고    scopus 로고
    • Digital microfluidic chips for chemical and biological applications
    • Fair RB, Digital microfluidic chips for chemical and biological applications, Conf Proc IEEE Eng Med Biol Soc 2009:6560-6564, 2009.
    • (2009) Conf Proc IEEE Eng Med Biol Soc , vol.2009 , pp. 6560-6564
    • Fair, R.B.1
  • 150
    • 77749345719 scopus 로고    scopus 로고
    • Integration of protein processing steps on a droplet microfluidics platform for MALDI-MS analysis
    • Chatterjee D, Ytterberg AJ, Son SU, Loo JA, Garrell RL, Integration of protein processing steps on a droplet microfluidics platform for MALDI-MS analysis, Anal Chem 82:2095-2101, 2010.
    • (2010) Anal Chem , vol.82 , pp. 2095-2101
    • Chatterjee, D.1    Ytterberg, A.J.2    Son, S.U.3    Loo, J.A.4    Garrell, R.L.5
  • 151
    • 65749098398 scopus 로고    scopus 로고
    • A microelectrode biosensor for real time monitoring of L-glutamate release
    • Tian F, Gourine AV, Huckstepp RT, Dale N, A microelectrode biosensor for real time monitoring of L-glutamate release, Anal Chim Acta 645:86-91, 2009.
    • (2009) Anal Chim Acta , vol.645 , pp. 86-91
    • Tian, F.1    Gourine, A.V.2    Huckstepp, R.T.3    Dale, N.4
  • 152
    • 76149086819 scopus 로고    scopus 로고
    • Amperometric detection of dopamine in vivo with an enzyme based carbon fiber microbiosensor
    • Njagi J, Chernov MM, Leiter JC, Andreescu S, Amperometric detection of dopamine in vivo with an enzyme based carbon fiber microbiosensor, Anal Chem 82:989-996, 2010.
    • (2010) Anal Chem , vol.82 , pp. 989-996
    • Njagi, J.1    Chernov, M.M.2    Leiter, J.C.3    Andreescu, S.4
  • 153
    • 40649115664 scopus 로고    scopus 로고
    • A cytochrome C modified-conducting polymer microelectrode for monitoring in vivo changes in nitric oxide
    • Alvin Koh WC, Rahman MA, Choe ES, Lee DK, Shim YB, A cytochrome C modified-conducting polymer microelectrode for monitoring in vivo changes in nitric oxide, Biosens Bioelectron 23:1374-1381, 2008.
    • (2008) Biosens Bioelectron , vol.23 , pp. 1374-1381
    • Alvin Koh, W.C.1    Rahman, M.A.2    Choe, E.S.3    Lee, D.K.4    Shim, Y.B.5
  • 155
    • 50849131951 scopus 로고    scopus 로고
    • Silicon wafer-based platinum microelectrode array biosensor for near real-time measurement of glutamate in vivo
    • Wassum KM, Tolosa VM, Wang J, Walker E, Monbouquette HG, Maidment NT, Silicon wafer-based platinum microelectrode array biosensor for near real-time measurement of glutamate in vivo, Sensors Basel Sensors 8:5023-5036, 2008.
    • (2008) Sensors Basel Sensors , vol.8 , pp. 5023-5036
    • Wassum, K.M.1    Tolosa, V.M.2    Wang, J.3    Walker, E.4    Monbouquette, H.G.5    Maidment, N.T.6
  • 156
    • 77955277475 scopus 로고    scopus 로고
    • Implantable MEMS compressive stress sensors: Design, fabrication and calibration with application to the disc annulus
    • Glos DL, Sauser FE, Papautsky I, Bylski-Austrow DI, Implantable MEMS compressive stress sensors: Design, fabrication and calibration with application to the disc annulus, J Biomech 43:2244-2248, 2010.
    • (2010) J Biomech , vol.43 , pp. 2244-2248
    • Glos, D.L.1    Sauser, F.E.2    Papautsky, I.3    Bylski-Austrow, D.I.4
  • 159
    • 33845969837 scopus 로고    scopus 로고
    • Membrane thickness design of implantable bio-MEMS sensors for the in-situ monitoring of blood flow
    • DOI 10.1007/s10856-006-0659-8, Special Section: Selected Papers from the ASME Winter Annual Meeting: Materials and Interfaces with Medicine and Dentistry
    • Steeves CA, Young YL, Liu Z, Bapat A, Bhalerao K, Soboyejo AB, Soboyejo WO, Membrane thickness design of implantable bio-MEMS sensors for the insitu monitoring of blood flow, J Mater Sci Mater Med 18:25-37, 2007. (Pubitemid 46046714)
    • (2007) Journal of Materials Science: Materials in Medicine , vol.18 , Issue.1 , pp. 25-37
    • Steeves, C.A.1    Young, Y.L.2    Liu, Z.3    Bapat, A.4    Bhalerao, K.5    Soboyejo, A.B.O.6    Soboyejo, W.O.7
  • 160
    • 33745625688 scopus 로고    scopus 로고
    • Development of a new sensor based on micro-electro-mechanical systems for objective in vivo measurement of the cutaneos temperature: Application to foundations
    • DOI 10.1111/j.0909-752X.2006.00156.x
    • Korichi R,Mac-Mary S, Elkhyat A, Sainthillier JM, Ransch P, Humbert P, Viviant E, Gazano G, Mahe C, Development of a new sensor based on micro-electro-mechanical systems for objective in vivo measurement of the cutaneous temperature: Application to foundations, Skin Res Technol 12:206-210, 2006. (Pubitemid 43985015)
    • (2006) Skin Research and Technology , vol.12 , Issue.3 , pp. 206-210
    • Korichi, R.1    Mac-Mary, S.2    Elkhyat, A.3    Sainthillier, J.-M.4    Ransch, P.5    Humbert, P.6    Viviant, E.7    Gazano, G.8    Mahe, C.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.