A porous silicon-based optical interferometric biosensor

Science

Volumn 278, Issue 5339, 1997, Pages 840-843

  Lin, Victor S Y ^a   Motesharei, Kianoush ^a   Dancil, Keiki Pua S ^b   Sailor, Michael J ^b   Ghadiri, M Reza ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; DNA; FABRY-PEROT INTERFEROMETERS; MOLECULAR ORIENTATION; OLIGOMERS; OPTICAL SENSORS; ORGANIC COMPOUNDS; POROUS SILICON; PROTEINS; REFRACTIVE INDEX; SEMICONDUCTOR MATERIALS;

BIOTIN; DIGOXIGENIN; STREPTAVIDIN;

BIOSENSORS;

ANTIBODY; BIOTIN; DIGOXIGENIN; DNA; OLIGOMER; SILICON DERIVATIVE; STREPTAVIDIN;

ARTICLE; BIOSENSOR; DERIVATIZATION; DNA SEQUENCE; INTERFEROMETRY; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; REFRACTION INDEX; SEMICONDUCTOR;

ANIMALS; BIOSENSING TECHNIQUES; BIOTINYLATION; DIGOXIGENIN; DNA, COMPLEMENTARY; INTERFEROMETRY; MICE; SENSITIVITY AND SPECIFICITY; SILICON; STREPTAVIDIN;

EID: 1842376840     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.278.5339.840     Document Type: Article

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29. Financial support was provided by the Office of Naval Research (N000149511293) through the Multi-Disciplinary University Research Initiative of the Department of Defense. We thank J. E. Kyte and R. C. Dynes for helpful discussions. M.R.G. thanks the Scripps Research Institute for matching equipment funds. V.S.-Y.L. was supported under a Skaggs Institute post-doctoral fellowship, K.M. under an NIH postdoctoral fellowship (GM18309), and K.S.D. under an NIH predoctoral fellowship (2SO6 GM47165-06).