Chitosan-alginate 3D scaffolds as a mimic of the glioma tumor microenvironment

Biomaterials

Volumn 31, Issue 22, 2010, Pages 5903-5910

  Kievit, Forrest M ^a   Florczyk, Stephen J ^a   Leung, Matthew C ^a   Veiseh, Omid ^a   Park, James O ^b   Disis, Mary L ^b   Zhang, Miqin ^a  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Alginate; Chitosan; Glioma; Natural polymer; Scaffold; Tumor microenvironment

Indexed keywords

3D SCAFFOLDS; ANIMAL STUDIES; ANTI-CANCER THERAPEUTICS; C6 CELLS; CANCER CELLS; CELL BIOLOGY; EFFECTIVE THERAPY; EXPERIMENTAL DESIGN; EXTRACELLULAR MATRICES; GLIOMA; GLIOMA CELLS; IN-VITRO; IN-VIVO; LAMININ; MATRIX; MICROENVIRONMENTS; NUDE MICE; SCAFFOLD PLATFORMS; THREE-DIMENSIONAL (3D); TUMOR CELLS; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR MODELS;

ALGINATE; ANIMAL CELL CULTURE; BIOPOLYMERS; BLOOD VESSELS; CELL CULTURE; CELL PROLIFERATION; CHITIN; CHITOSAN; ENZYME ACTIVITY; STANDARDIZATION; THREE DIMENSIONAL; TISSUE CULTURE; TUMORS;

SCAFFOLDS;

ALGINIC ACID; CHITOSAN; FIBRONECTIN; GELATINASE A; LAMININ; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GLIOMA; HUMAN; HUMAN CELL; MATRIX ATTACHMENT REGION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; SCANNING ELECTRON MICROSCOPY; THREE DIMENSIONAL IMAGING; TUMOR GROWTH; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

ALGINATES; ANIMALS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHITOSAN; GLIOMA; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; MALE; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; RATS; TISSUE SCAFFOLDS;

ANIMALIA; MUS MUSCULUS; RATTUS;

EID: 77953081587     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.03.062     Document Type: Article

References (29)

1. Mirimanoff R.O., Gorlia T., Mason W., Van den Bent M.J., Kortmann R.D., Fisher B., et al. Radiotherapy and temozolomide for newly diagnosed glioblastoma: recursive partitioning analysis of the EORTC 26981/22981-NCIC CE3 phase III randomized trial. J Clin Oncol 2006, 24:2563-2569.
2. Mercer R.W., Tyler M.A., Ulasov I.V., Lesniak M.S. Targeted therapies for malignant glioma: progress and potential. BioDrugs 2009, 23:25-35.
3. Hambley T.W., Hait W.N. Is anticancer drug development heading in the right direction?. Cancer Res 2009, 69:1259-1262.
4. Smalley K.S., Lioni M., Herlyn M. Life isn't flat: taking cancer biology to the next dimension. In Vitro Cell Dev Biol Anim 2006, 42:242-247.
5. Petersen O.W., Ronnov-Jessen L., Howlett A.R., Bissell M.J. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci U S A 1992, 89:9064-9068.
6. dit Faute M.A., Laurent L., Ploton D., Poupon M.F., Jardillier J.C., Bobichon H. Distinctive alterations of invasiveness, drug resistance and cell-cell organization in 3D-cultures of MCF-7, a human breast cancer cell line, and its multidrug resistant variant. Clin Exp Metastasis 2002, 19:161-168.
7. Fischbach C., Chen R., Matsumoto T., Schmelzle T., Brugge J.S., Polverini P.J., et al. Engineering tumors with 3D scaffolds. Nat Methods 2007, 4:855-860.
8. Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005, 23:47-55.
9. Weaver V.M., Petersen O.W., Wang F., Larabell C.A., Briand P., Damsky C., et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997, 137:231-245.
10. Kumar S., Weaver V.M. Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Rev 2009.
11. Yang Y., Basu S., Tomasko D.L., Lee L.J., Yang S.T. Fabrication of well-defined PLGA scaffolds using novel microembossing and carbon dioxide bonding. Biomaterials 2005, 26:2585-2594.
12. Orive G., Tam S.K., Pedraz J.L., Halle J.P. Biocompatibility of alginate-poly-l-lysine microcapsules for cell therapy. Biomaterials 2006, 27:3691-3700.
13. Hirano S., Seino H., Akiyama Y., Nonka I. Biocompatibility of chitosan by oral and intravenous administration. Crit Rev Ther Drug Carrier Syst 1988, 15:143-198.
14. Li Z., Ramay H.R., Hauch K.D., Xiao D., Zhang M. Chitosan-alginate hybrid scaffolds for bone tissue engineering. Biomaterials 2005, 26:3919-3928.
15. Li Z., Zhang M. Chitosan-alginate as scaffolding material for cartilage tissue engineering. J Biomed Mater Res A 2005, 75:485-493.
16. Li Z., Leung M., Hopper R., Ellenbogen R., Zhang M. Feeder-free self-renewal of human embryonic stem cells in 3D porous natural polymer scaffolds. Biomaterials 2010, 31:404-412.
17. Zheng X., Shen G., Yang X., Liu W. Most C6 cells are cancer stem cells: evidence from clonal and population analyses. Cancer Res 2007, 67:3691-3697.
18. Shen G., Shen F., Shi Z., Liu W., Hu W., Zheng X., et al. Identification of cancer stem-like cells in the C6 glioma cell line and the limitation of current identification methods. In Vitro Cell Dev Biol Anim 2008, 44:280-289.
19. Kondo T., Setoguchi T., Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci U S A 2004, 101:781-786.
20. Cretu A., Fotos J.S., Little B.W., Galileo D.S. Human and rat glioma growth, invasion, and vascularization in a novel chick embryo brain tumor model. Clin Exp Metastasis 2005, 22:225-236.
21. Chau Y., Padera R.F., Dang N.M., Langer R. Antitumor efficacy of a novel polymer-peptide-drug conjugate in human tumor xenograft models. Int J Cancer 2006, 118:1519-1526.
22. Yamaguchi H., Wyckoff J., Condeelis J. Cell migration in tumors. Curr Opin Cell Biol 2005, 17:559-564.
23. Hoelzinger D.B., Demuth T., Berens M.E. Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J Natl Cancer Inst 2007, 99:1583-1593.
24. Plate K.H., Breier G., Weich H.A., Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 1992, 359:845-848.
25. Ferrara N., Carver-Moore K., Chen H., Dowd M., Lu L., O'Shea K.S., et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 1996, 380:439-442.
26. Jouanneau E. Angiogenesis and gliomas: current issues and development of surrogate markers. Neurosurgery 2008, 62:31-50. [discussion 2].
27. Wang F., Weaver V.M., Petersen O.W., Larabell C.A., Dedhar S., Briand P., et al. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A 1998, 95:14821-14826.
28. O'Brien L.E., Jou T.S., Pollack A.L., Zhang Q., Hansen S.H., Yurchenco P., et al. Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly. Nat Cell Biol 2001, 3:831-838.
29. Croft D.R., Sahai E., Mavria G., Li S., Tsai J., Lee W.M., et al. Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis. Cancer Res 2004, 64:8994-9001.