Peptide nucleic acids with a structurally biased backbone. Updated review and emerging challenges

Current Topics in Medicinal Chemistry

Volumn 11, Issue 12, 2011, Pages 1535-1554

  Corradini, Roberto ^a   Sforza, Stefano ^a   Tedeschi, Tullia ^a   Totsingan, Filbert ^a,b   Manicardi, Alex ^a   Marchelli, Rosangela ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

Antigene; Antisense; Cellular uptake; Cyclic PNA,chirality; Modified PNAs

Indexed keywords

2,6 DIAMINOPURINE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; DOUBLE STRANDED DNA; MESSENGER RNA PRECURSOR; MICRORNA; PEPTIDE NUCLEIC ACID; RNA POLYMERASE; THIOURACIL;

BINDING AFFINITY; BIOAVAILABILITY; CANCER CELL CULTURE; CHEMICAL MODIFICATION; CHIRALITY; DNA SPLICING; GENE TARGETING; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DNA BINDING; PROTEIN STRUCTURE; REVIEW; RNA DEGRADATION; RNA SPLICING; RNA TRANSCRIPTION; RNA TRANSLATION; STEREOCHEMISTRY; TARGETED GENE REPAIR;

ANIMALS; GENE EXPRESSION REGULATION; HUMANS; NUCLEIC ACID CONFORMATION; PEPTIDE NUCLEIC ACIDS; RNA;

EID: 79960030494     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802611795860979     Document Type: Review

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