Crystal structure of chiral γpNA with complementary DNA strand: Insights into the stability and specificity of recognition and conformational preorganization

Journal of the American Chemical Society

Volumn 132, Issue 31, 2010, Pages 10717-10727

  Yeh, Joanne I ^a   Shivachev, Boris ^a   Rapireddy, Srinivas ^b   Crawford, Matthew J ^b   Gil, Roberto R ^b   Du, Shoucheng ^a   Madrid, Marcela ^c   Ly, Danith H ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c PITTSBURGH SUPERCOMPUTING CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMALOUS DIFFRACTION; BEFORE AND AFTER; BUILDING BLOCKES; CONFORMATIONAL FLEXIBILITY; CONFORMATIONAL PREORGANIZATION; CONFORMATIONAL STATE; DNA DUPLEXES; DNA STRANDS; FUTURE DESIGNS; HELICAL CONFORMATION; HIGH RESOLUTION; HYBRID DUPLEX; NEW STRUCTURES; NMR ANALYSIS; RIGHT-HANDED HELIX;

DNA; GENES; ZINC;

CRYSTAL STRUCTURE;

CATION; COMPLEMENTARY DNA; PEPTIDE NUCLEIC ACID; ZINC DERIVATIVE;

ANALYSIS; ARTICLE; BIOTECHNOLOGY; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CHIRALITY; CONFORMATION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIFFRACTION; DNA STRAND; HYBRIDIZATION; HYDRATION; NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

DNA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PEPTIDE NUCLEIC ACIDS; THERMODYNAMICS;

EID: 77955348086     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja907225d     Document Type: Article

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