A simple cytosine to G-clamp nucleobase substitution enables chiral γ-PNAs to invade mixed-sequence double-helical B-form DNA

ChemBioChem

Volumn 9, Issue 15, 2008, Pages 2388-2391

  Chenna, Venugopal ^a,b   Rapireddy, Srinivas ^a   Sahu, Bichismita ^a   Ausin, Cristina ^c   Pedroso, Enrique ^c   Ly, Danith H ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b DEPARTMENT OF PATHOLOGY   (United States)

^c UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Chiral gamma PNA; DNA recognition; DNA strand invasion; Helical PNA; Nucleic acids

Indexed keywords

ADENINE; CYTOSINE; DOUBLE STRANDED DNA; GUANINE; NUCLEIC ACID BASE; THYMIDINE;

ARTICLE; CHIRALITY; CONCENTRATION (PARAMETERS); DNA BINDING; DNA CONFORMATION; DNA DENATURATION; DNA SEQUENCE; GEL MOBILITY SHIFT ASSAY; IONIC STRENGTH; MOLECULAR INTERACTION; MOLECULAR STABILITY; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; THERMODYNAMICS;

BASE SEQUENCE; CIRCULAR DICHROISM; CYTOSINE; DNA; GUANOSINE; NUCLEIC ACID CONFORMATION; PEPTIDE NUCLEIC ACIDS; STEREOISOMERISM;

EID: 54349087593     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800441     Document Type: Article

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