Synthesis of cell-permeable peptide nucleic acids and characterization of their hybridization and uptake properties

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 18, 2006, Pages 4931-4935

  Zhou, Peng ^a   Dragulescu Andrasi, Anca ^a   Bhattacharya, Birendra ^b   O'Keefe, Heather ^b   Vatta, Paolo ^b   Hyldig Nielsen, Jens J ^b   Ly, Danith H ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b APPLIED BIOSYSTEMS   (United States)

Author keywords

Cell permeable; Endoplasmic reticulum; ER; GPNA; Guanidine based peptide nucleic acid; Monomers; Oligomers; Synthesis

Indexed keywords

2,6 DIAMINOPURINE; ADENINE; CYTOSINE; DNA; GUANIDINE; GUANINE; MONOMER; OLIGOMER; PEPTIDE NUCLEIC ACID; THIOURACIL; THYMINE;

ARTICLE; DRUG DISTRIBUTION; DRUG UPTAKE; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HYBRIDIZATION; MAMMAL CELL;

CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; NUCLEIC ACID HYBRIDIZATION; PEPTIDE NUCLEIC ACIDS; TRANSITION TEMPERATURE;

MAMMALIA;

EID: 33746822930     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.06.052     Document Type: Article

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