-
1
-
-
11144356131
-
The use of cell-penetrating peptides as a tool for gene regulation
-
Jarver, P., Langel, U. (2004) The use of cell-penetrating peptides as a tool for gene regulation. Drug Discov Today 9, 395-402.
-
(2004)
Drug Discov Today
, vol.9
, pp. 395-402
-
-
Jarver, P.1
Langel, U.2
-
2
-
-
1642321105
-
Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides
-
Moulton, H. M., Nelson, M. H., Hatlevig, S. A., Reddy, M. T., and Iversen, P. L. (2004) Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides. Bioconjugate Chem. 15, 290-299.
-
(2004)
Bioconjugate Chem.
, vol.15
, pp. 290-299
-
-
Moulton, H.M.1
Nelson, M.H.2
Hatlevig, S.A.3
Reddy, M.T.4
Iversen, P.L.5
-
3
-
-
0035374402
-
Cellular translocation of proteins by transportan
-
Pooga, M., Kut, C., Kihlmark, M., Hallbrink, M., Fernaeus, S., Raid, R., Land, T., Hallberg, E., Bartfai, T., and Langel, U. (2001) Cellular translocation of proteins by transportan. FASEB J. 15, 1451-1453.
-
(2001)
FASEB J.
, vol.15
, pp. 1451-1453
-
-
Pooga, M.1
Kut, C.2
Kihlmark, M.3
Hallbrink, M.4
Fernaeus, S.5
Raid, R.6
Land, T.7
Hallberg, E.8
Bartfai, T.9
Langel, U.10
-
4
-
-
0345275894
-
Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential
-
Terrone, D., Sang, S. L., Roudaia, L., and Silvius, J. R. (2003) Penetratin and related cell-penetrating cationic peptides can translocate across lipid bilayers in the presence of a transbilayer potential. Biochemistry 42, 13787-13799.
-
(2003)
Biochemistry
, vol.42
, pp. 13787-13799
-
-
Terrone, D.1
Sang, S.L.2
Roudaia, L.3
Silvius, J.R.4
-
5
-
-
0038726020
-
Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells
-
Thoren, P. E., Persson, D., Isakson, P., Goksor, M., Onfelt, A., and Norden, B. (2003) Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells. Biochem. Biophys. Res. Commun. 307, 100-107.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 100-107
-
-
Thoren, P.E.1
Persson, D.2
Isakson, P.3
Goksor, M.4
Onfelt, A.5
Norden, B.6
-
6
-
-
3843092828
-
Chances and pitfalls of cell penetrating peptides for cellular drug delivery
-
Trehin, R., and Merkle, H. P. (2004) Chances and pitfalls of cell penetrating peptides for cellular drug delivery. Eur. J. Pharm. Biopharm. 58, 209-223.
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 209-223
-
-
Trehin, R.1
Merkle, H.P.2
-
7
-
-
0141907727
-
Cellular uptake [correction of utake] of the Tat peptide: An endocytosis mechanism following ionic interactions
-
Vives, E. (2003) Cellular uptake [correction of utake] of the Tat peptide: an endocytosis mechanism following ionic interactions. J. Mol. Recognit. 16, 265-271.
-
(2003)
J. Mol. Recognit.
, vol.16
, pp. 265-271
-
-
Vives, E.1
-
8
-
-
0033427790
-
Homeodomain-derived peptides. In and out of the cells
-
Prochiantz, A. (1999) Homeodomain-derived peptides. In and out of the cells. Ann. N. Y. Acad. Sci. 886, 172-179.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.886
, pp. 172-179
-
-
Prochiantz, A.1
-
9
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
Derossi, D., Chassaing, G., and Prochiantz, A. (1998) Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol. 8, 84-87.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
10
-
-
0032508926
-
Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically
-
Oehlke, J., Scheller, A., Wiesner, B., Krause, E., Beyermann, M., Klauschenz, E., Melzig, M., and Bienert, M. (1998) Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically. Biochim. Biophys. Acta 1414, 127-139.
-
(1998)
Biochim. Biophys. Acta
, vol.1414
, pp. 127-139
-
-
Oehlke, J.1
Scheller, A.2
Wiesner, B.3
Krause, E.4
Beyermann, M.5
Klauschenz, E.6
Melzig, M.7
Bienert, M.8
-
11
-
-
0035989846
-
Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates
-
Koppelhus, U., Awasthi, S. K., Zachar, V., Holst, H. U., Ebbesen, P., and Nielsen, P. E. (2002) Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates. Antisense Nucleic Acid Drug Dev. 12, 51-63.
-
(2002)
Antisense Nucleic Acid Drug Dev.
, vol.12
, pp. 51-63
-
-
Koppelhus, U.1
Awasthi, S.K.2
Zachar, V.3
Holst, H.U.4
Ebbesen, P.5
Nielsen, P.E.6
-
12
-
-
9144230176
-
Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: Evidence against direct passage through phospholipid bilayers
-
Ross, M. F., Filipovska, A., Smith, R. A., Gait, M. J., and Murphy, M. P. (2004) Cell-penetrating peptides do not cross mitochondrial membranes even when conjugated to a lipophilic cation: evidence against direct passage through phospholipid bilayers. Biochem. J. 383, 457-468.
-
(2004)
Biochem. J.
, vol.383
, pp. 457-468
-
-
Ross, M.F.1
Filipovska, A.2
Smith, R.A.3
Gait, M.J.4
Murphy, M.P.5
-
13
-
-
0346460957
-
Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake
-
Richard, J. P., Melikov, K., Vives, E., Ramos, C., Verbeure, B., Gait, M. J., Chernomordik, L. V., and Lebleu, B. (2003) Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J. Biol. Chem. 278, 585-590.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 585-590
-
-
Richard, J.P.1
Melikov, K.2
Vives, E.3
Ramos, C.4
Verbeure, B.5
Gait, M.J.6
Chernomordik, L.V.7
Lebleu, B.8
-
14
-
-
11844293998
-
The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblasts: Optical, biophysical, and metabolic evidence
-
Ziegler, A., Nervi, P., Durrenberger, M., and Seelig, J. (2005) The cationic cell-penetrating peptide CPP(TAT) derived from the HIV-1 protein TAT is rapidly transported into living fibroblasts: optical, biophysical, and metabolic evidence. Biochemistry 44, 138-148.
-
(2005)
Biochemistry
, vol.44
, pp. 138-148
-
-
Ziegler, A.1
Nervi, P.2
Durrenberger, M.3
Seelig, J.4
-
15
-
-
1642304434
-
Membrane binding and translocation of cell-penetrating peptides
-
Thoren, P. E., Persson, D., Esbjorner, E. K., Goksor, M., Lincoln, P., and Norden, B. (2004) Membrane binding and translocation of cell-penetrating peptides. Biochemistry 43, 3471-3489.
-
(2004)
Biochemistry
, vol.43
, pp. 3471-3489
-
-
Thoren, P.E.1
Persson, D.2
Esbjorner, E.K.3
Goksor, M.4
Lincoln, P.5
Norden, B.6
-
16
-
-
0035575843
-
Cargo delivery kinetics of cell-penetrating peptides
-
Hallbrink, M., Floren, A., Elmquist, A., Pooga, M., Bartfai, T., and Langel, U. (2001) Cargo delivery kinetics of cell-penetrating peptides. Biochim. Biophys. Acta 1515, 101-109.
-
(2001)
Biochim. Biophys. Acta
, vol.1515
, pp. 101-109
-
-
Hallbrink, M.1
Floren, A.2
Elmquist, A.3
Pooga, M.4
Bartfai, T.5
Langel, U.6
-
17
-
-
9244255342
-
Protein cargo delivery properties of cell-penetrating peptides. A comparative study
-
Saalik, P., Elmquist, A., Hansen, M., Padari, K., Saar, K., Viht, K., Langel, U., and Pooga, M. (2004) Protein cargo delivery properties of cell-penetrating peptides. A comparative study. Bioconjugate Chem. 15, 1246-1253.
-
(2004)
Bioconjugate Chem.
, vol.15
, pp. 1246-1253
-
-
Saalik, P.1
Elmquist, A.2
Hansen, M.3
Padari, K.4
Saar, K.5
Viht, K.6
Langel, U.7
Pooga, M.8
-
18
-
-
0036298282
-
Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
-
Astriab-Fisher, A., Sergueev, D., Fisher, M., Shaw, B. R., and Juliano, R. L. (2002) Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: effects on cellular uptake, binding to target sequences, and biologic actions. Pharm. Res. 19, 744-754.
-
(2002)
Pharm. Res.
, vol.19
, pp. 744-754
-
-
Astriab-Fisher, A.1
Sergueev, D.2
Fisher, M.3
Shaw, B.R.4
Juliano, R.L.5
-
19
-
-
4744348164
-
Arginine-rich cell-penetrating peptides with uncharged antisense oligomers
-
Moulton, H. M., and Moulton, J. D. (2004) Arginine-rich cell-penetrating peptides with uncharged antisense oligomers. Drug Discov. Today 9, 870.
-
(2004)
Drug Discov. Today
, vol.9
, pp. 870
-
-
Moulton, H.M.1
Moulton, J.D.2
-
20
-
-
0032485884
-
Up-regulation of luciferase gene expression with antisense oligonucleotides: Implications and applications in functional assay development
-
Kang, S. H., Cho, M. J., and Kole, R. (1998) Up-regulation of luciferase gene expression with antisense oligonucleotides: implications and applications in functional assay development. Biochemistry 37, 6235-6239.
-
(1998)
Biochemistry
, vol.37
, pp. 6235-6239
-
-
Kang, S.H.1
Cho, M.J.2
Kole, R.3
-
21
-
-
4544379668
-
Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates
-
Shiraishi, T., and Nielsen, P. E. (2004) Down-regulation of MDM2 and activation of p53 in human cancer cells by antisense 9-aminoacridine-PNA (peptide nucleic acid) conjugates. Nucleic Acids Res. 32, 4893-4902.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 4893-4902
-
-
Shiraishi, T.1
Nielsen, P.E.2
-
22
-
-
0031754150
-
Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
-
Pooga, M., Soomets, U., Hallbrink, M., Valkna, A., Saar, K., Rezaei, K., Kahl, U., Hao, J. X., Xu, X. J., Wiesenfeld-Hallin, Z., Hokfelt, T., Bartfai, T., and Langel, U. (1998) Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol. 16, 857-861.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 857-861
-
-
Pooga, M.1
Soomets, U.2
Hallbrink, M.3
Valkna, A.4
Saar, K.5
Rezaei, K.6
Kahl, U.7
Hao, J.X.8
Xu, X.J.9
Wiesenfeld-Hallin, Z.10
Hokfelt, T.11
Bartfai, T.12
Langel, U.13
-
23
-
-
0037428953
-
Cellular delivery of peptide nucleic acid (PNA)
-
Koppelhus, U., and Nielsen, P. E. (2003) Cellular delivery of peptide nucleic acid (PNA). Adv Drug Deliv. Rev. 55, 267-280.
-
(2003)
Adv Drug Deliv. Rev.
, vol.55
, pp. 267-280
-
-
Koppelhus, U.1
Nielsen, P.E.2
-
24
-
-
0035075441
-
Bactericidal antisense effects of peptide-PNA conjugates
-
Good, L., Awasthi, S. K., Dryselius, R., Larsson, O., and Nielsen, P. E. (2001) Bactericidal antisense effects of peptide-PNA conjugates. Nat. Biotechnol. 19, 360-364.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 360-364
-
-
Good, L.1
Awasthi, S.K.2
Dryselius, R.3
Larsson, O.4
Nielsen, P.E.5
-
25
-
-
0036510769
-
Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli
-
Eriksson, M., Nielsen, P. E., and Good, L. (2002) Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli. J. Biol. Chem. 277, 7144-7147.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7144-7147
-
-
Eriksson, M.1
Nielsen, P.E.2
Good, L.3
-
26
-
-
0035196836
-
Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: Saturation kinetics and specificity
-
Rousselle, C., Smirnova, M., Clair, P., Lefauconnier, J. M., Chavanieu, A., Calas, B., Scherrmann, J. M., and Temsamani, J. (2001) Enhanced delivery of doxorubicin into the brain via a peptide-vector-mediated strategy: saturation kinetics and specificity. J. Pharmacol. Exp. Ther. 296, 124-131.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 124-131
-
-
Rousselle, C.1
Smirnova, M.2
Clair, P.3
Lefauconnier, J.M.4
Chavanieu, A.5
Calas, B.6
Scherrmann, J.M.7
Temsamani, J.8
-
27
-
-
18044374814
-
Improved brain uptake and pharmacological activity profile of morphine-6-glucuronide using a peptide-vector-mediated strategy
-
Temsamani, J., Bonnafous, C., Rousselle, C., Fraisse, Y., Clair, P., Granier, L. A., Rees, A. R., Kaczorek, M., Scherrmann, J. M. (2005) Improved brain uptake and pharmacological activity profile of morphine-6-glucuronide using a peptide-vector-mediated strategy. J. Pharmacol. Exp. Ther. 313, 712-719.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.313
, pp. 712-719
-
-
Temsamani, J.1
Bonnafous, C.2
Rousselle, C.3
Fraisse, Y.4
Clair, P.5
Granier, L.A.6
Rees, A.R.7
Kaczorek, M.8
Scherrmann, J.M.9
-
28
-
-
0034061532
-
Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal
-
Cutrona, G., Carpaneto, E. M., Ulivi, M., Roncella, S., Landt, O., Ferrarini, M., and Boffa, L. C. (2000) Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal. Nat. Biotechnol. 18, 300-303.
-
(2000)
Nat. Biotechnol.
, vol.18
, pp. 300-303
-
-
Cutrona, G.1
Carpaneto, E.M.2
Ulivi, M.3
Roncella, S.4
Landt, O.5
Ferrarini, M.6
Boffa, L.C.7
-
29
-
-
0033374355
-
Peptide nucleic acid delivery to human mitochondria
-
Chinnery, P. F., Taylor, R. W., Diekert, K., Lill, R., Turnbull, D. M., and Lightowlers, R. N. (1999) Peptide nucleic acid delivery to human mitochondria. Gene Ther. 6, 1919-1928.
-
(1999)
Gene Ther.
, vol.6
, pp. 1919-1928
-
-
Chinnery, P.F.1
Taylor, R.W.2
Diekert, K.3
Lill, R.4
Turnbull, D.M.5
Lightowlers, R.N.6
-
30
-
-
0036357672
-
Synthesis of PNA-peptide conjugates
-
Awasthi, S. K., and Nielsen, P. E. (2002) Synthesis of PNA-peptide conjugates. Methods Mol. Biol. 208, 43-52.
-
(2002)
Methods Mol. Biol.
, vol.208
, pp. 43-52
-
-
Awasthi, S.K.1
Nielsen, P.E.2
-
31
-
-
0038246490
-
Synthesis and properties of ester-linked peptide nucleic acid prodrug conjugates
-
Bendifallah, N., Kristensen, E., Dahl, O., Koppelhus, U., and Nielsen, P. E. (2003) Synthesis and properties of ester-linked peptide nucleic acid prodrug conjugates. Bioconjugate Chem. 14, 588-592.
-
(2003)
Bioconjugate Chem.
, vol.14
, pp. 588-592
-
-
Bendifallah, N.1
Kristensen, E.2
Dahl, O.3
Koppelhus, U.4
Nielsen, P.E.5
-
32
-
-
33645825629
-
Evaluation of transfection protocols for unmodified and modified peptide nucleic acid (PNA) oligomers
-
Rasmussen, F. W., Bendifallah, N., Zachar, V., Shiraishi, T., Fink, T., Ebbesen, P., Nielsen, P. E., and Koppelhus, U. (2006) Evaluation of transfection protocols for unmodified and modified peptide nucleic acid (PNA) oligomers. Oligonucleotides 16, 42-56.
-
(2006)
Oligonucleotides
, vol.16
, pp. 42-56
-
-
Rasmussen, F.W.1
Bendifallah, N.2
Zachar, V.3
Shiraishi, T.4
Fink, T.5
Ebbesen, P.6
Nielsen, P.E.7
Koppelhus, U.8
-
33
-
-
0033040441
-
Intracellular localization of oligonucleotides: Influence of fixative protocols
-
Pichon, C., Monsigny, M., and Roche, A. C. (1999) Intracellular localization of oligonucleotides: influence of fixative protocols. Antisense Nucleic Acid Drug Dev. 9, 89-93.
-
(1999)
Antisense Nucleic Acid Drug Dev.
, vol.9
, pp. 89-93
-
-
Pichon, C.1
Monsigny, M.2
Roche, A.C.3
-
34
-
-
0029980721
-
Antisense properties of duplex- and triplex-forming PNAs
-
Knudsen, H., and Nielsen, P. E. (1996) Antisense properties of duplex- and triplex-forming PNAs. Nucleic Acids Res. 24, 494-500.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 494-500
-
-
Knudsen, H.1
Nielsen, P.E.2
-
35
-
-
0030842070
-
Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA
-
Koppelhus, U., Zachar, V., Nielsen, P. E., Liu, X., Eugen-Olsen, J., and Ebbesen, P. (1997) Efficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA. Nucleic Acids Res. 25, 2167-2173.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2167-2173
-
-
Koppelhus, U.1
Zachar, V.2
Nielsen, P.E.3
Liu, X.4
Eugen-Olsen, J.5
Ebbesen, P.6
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