메뉴 건너뛰기




Volumn 18, Issue 3, 2000, Pages 300-303

Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal

Author keywords

Anti gene; C myc; Lymphomas; Nuclear localization signal (NLS) peptide; Peptide nucleic acid (PNA)

Indexed keywords

PEPTIDE NUCLEIC ACID;

EID: 0034061532     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/73745     Document Type: Article
Times cited : (225)

References (31)
  • 1
    • 84990238662 scopus 로고
    • Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone
    • Egholm, M., Buchardt, O., Nielsen, P.E. & Berg, R.H. Peptide nucleic acids (PNA). Oligonucleotide analogues with an achiral peptide backbone. J. Am Chem. Soc. 114, 1895-1897 (1992).
    • (1992) J. Am Chem. Soc. , vol.114 , pp. 1895-1897
    • Egholm, M.1    Buchardt, O.2    Nielsen, P.E.3    Berg, R.H.4
  • 2
    • 0027364174 scopus 로고
    • PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules
    • Egholm, M. et al. PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature 365, 566-563 (1993).
    • (1993) Nature , vol.365 , pp. 566-1563
    • Egholm, M.1
  • 3
    • 0028129843 scopus 로고
    • Stability of peptide nucleic acids in human serum and cellular extracts
    • Demidov, V.V. et al. Stability of peptide nucleic acids in human serum and cellular extracts. Biochem. Pharmacol. 48, 1310-1313 (1994).
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1310-1313
    • Demidov, V.V.1
  • 4
    • 0030006487 scopus 로고    scopus 로고
    • Invasion of the CAG triplet repeats by a complementary Peptide Nucleic Acids inhibits transcription of the Androgen Receptor and TATA-Binding Protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
    • Boffa, L.C., Morris, R.L., Carpaneto, E.M., Louissant, M. & Allfrey, V.G. Invasion of the CAG triplet repeats by a complementary Peptide Nucleic Acids inhibits transcription of the Androgen Receptor and TATA-Binding Protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence. J. Biol. Chem. 271, 13228-13233 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 13228-13233
    • Boffa, L.C.1    Morris, R.L.2    Carpaneto, E.M.3    Louissant, M.4    Allfrey, V.G.5
  • 5
    • 0030623838 scopus 로고    scopus 로고
    • Contrasting effects of PNA invasion on chimeric DMMYC gene on transcription of its myc and PVT domains
    • Boffa, L.C., Carpaneto, E.M., Mariani, M.R., Louissant, M. & Allfrey, V.G. Contrasting effects of PNA invasion on chimeric DMMYC gene on transcription of its myc and PVT domains. Oncology Res. 9, 41-51 (1997).
    • (1997) Oncology Res. , vol.9 , pp. 41-51
    • Boffa, L.C.1    Carpaneto, E.M.2    Mariani, M.R.3    Louissant, M.4    Allfrey, V.G.5
  • 6
    • 0027104702 scopus 로고
    • Antisense and antigene properties of Peptide Nucleic Acids
    • Hanvey, C.J. et al. Antisense and antigene properties of Peptide Nucleic Acids. Science 258, 1481-1485 (1992).
    • (1992) Science , vol.258 , pp. 1481-1485
    • Hanvey, C.J.1
  • 7
    • 0030841714 scopus 로고    scopus 로고
    • Transformed and immortalized cellular uptake of oligodeoxynucleoside phosphorothioates, 3′-alkylamino oligodeoxynucleotides, 2′-O-methyl oligoribonucleotides, oligodeoxynucleosides methylphosphonates, and Peptides Nucleic Acids
    • Gray, D.G, Basu, S. & Wickstrom E. Transformed and immortalized cellular uptake of oligodeoxynucleoside phosphorothioates, 3′-alkylamino oligodeoxynucleotides, 2′-O-methyl oligoribonucleotides, oligodeoxynucleosides methylphosphonates, and Peptides Nucleic Acids. Biochem. Pharmacol. 53, 1465-1476 (1997).
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1465-1476
    • Gray, D.G.1    Basu, S.2    Wickstrom, E.3
  • 8
    • 0025081901 scopus 로고
    • The pathogenesis of Burkitt's lymphoma
    • Magrath, I. The pathogenesis of Burkitt's lymphoma. Adv. Cancer Res. 55, 133-270 (1990).
    • (1990) Adv. Cancer Res. , vol.55 , pp. 133-270
    • Magrath, I.1
  • 9
    • 0028897446 scopus 로고
    • Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt Lymphoma cells and normal centroblasts
    • Cutrona, G., Ulivi, M., Fais, F., Roncella, S. & Ferrarini, M. Transfection of the c-myc oncogene into normal Epstein-Barr virus-harboring B cells results in new phenotypic and functional features resembling those of Burkitt Lymphoma cells and normal centroblasts. J. Exp. Med. 181, 699-711 (1995).
    • (1995) J. Exp. Med. , vol.181 , pp. 699-711
    • Cutrona, G.1    Ulivi, M.2    Fais, F.3    Roncella, S.4    Ferrarini, M.5
  • 10
    • 0026096540 scopus 로고
    • Control of c-myc regulation in normal and neoplastic cells
    • Spencer, C.A. & Groudine, M. Control of c-myc regulation in normal and neoplastic cells. Adv. Cancer Res. 56, 1-48 (1991).
    • (1991) Adv. Cancer Res. , vol.56 , pp. 1-48
    • Spencer, C.A.1    Groudine, M.2
  • 11
    • 0021716406 scopus 로고
    • Short amino acid sequence able to specify nuclear localization
    • Kalderon, D., Roberts, B.L., Richardson, W.O. & Smith, E.A. Short amino acid sequence able to specify nuclear localization. Cell 39, 499-509 (1984).
    • (1984) Cell , vol.39 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.O.3    Smith, E.A.4
  • 12
    • 0029984570 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport
    • Gorlich, D. & Mattaj, I.W. Nucleocytoplasmic transport. Science 271, 1513-1518 (1996).
    • (1996) Science , vol.271 , pp. 1513-1518
    • Gorlich, D.1    Mattaj, I.W.2
  • 13
    • 0032859928 scopus 로고    scopus 로고
    • A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA
    • Branden, L.J., Mohamed, A.J. & Edvard Smith, C.I. A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat. Biotechnol. 17, 784-787 (1999).
    • (1999) Nat. Biotechnol. , vol.17 , pp. 784-787
    • Branden, L.J.1    Mohamed, A.J.2    Edvard Smith, C.I.3
  • 14
    • 0021378551 scopus 로고
    • Nucleotide sequence of the human c-myc locus: Provocative open reading frame within the first exon
    • Grazin, C et al. Nucleotide sequence of the human c-myc locus: provocative open reading frame within the first exon. EMBO J. 3, 383-387 (1984).
    • (1984) EMBO J. , vol.3 , pp. 383-387
    • Grazin, C.1
  • 15
    • 0031587384 scopus 로고    scopus 로고
    • Spermine conjugated peptide nucleic acids (spPNA): UV and fluorescence studies of PNA-DNA hybrids with improved stability
    • Gangamani, B.P., Kumar, V.A. & Ganesh, N.K. Spermine conjugated peptide nucleic acids (spPNA): UV and fluorescence studies of PNA-DNA hybrids with improved stability. Biochem. Biopbys. Res. Commun. 240, 778-782 (1997).
    • (1997) Biochem. Biopbys. Res. Commun. , vol.240 , pp. 778-782
    • Gangamani, B.P.1    Kumar, V.A.2    Ganesh, N.K.3
  • 16
    • 0022814978 scopus 로고
    • Extensive mutagenesis of the nuclear localization signal of simian virus 40 large T antigen
    • Colledge, W.H., Richardson, W.D., Edge, M.D. & Smith, A.E. Extensive mutagenesis of the nuclear localization signal of simian virus 40 large T antigen. Mol. Cell. Biol. 6, 4136-4138 (1986).
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4136-4138
    • Colledge, W.H.1    Richardson, W.D.2    Edge, M.D.3    Smith, A.E.4
  • 17
    • 0032491594 scopus 로고    scopus 로고
    • All four homochiral enantiomers of a nuclear localization sequence derived from c-myc serve as functional import signals
    • Saphire A.C., Bark S.J. & Gerace, L. All four homochiral enantiomers of a nuclear localization sequence derived from c-myc serve as functional import signals J. Biol. Chem. 273, 29764-29769 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 29764-29769
    • Saphire, A.C.1    Bark, S.J.2    Gerace, L.3
  • 18
    • 0023406843 scopus 로고
    • Calculating thermodinamics data for transition of any molecularity from equilibrium melting curves
    • Maky, L.A. & Bresslawer, K.Y. Calculating thermodinamics data for transition of any molecularity from equilibrium melting curves. Biopolymers 26, 1601-1620 (1987)
    • (1987) Biopolymers , vol.26 , pp. 1601-1620
    • Maky, L.A.1    Bresslawer, K.Y.2
  • 19
    • 0030018227 scopus 로고    scopus 로고
    • Ionic effects on the stability and conformation of Peptide Nucleic Acid complexes
    • Tomac, S. et al. Ionic effects on the stability and conformation of Peptide Nucleic Acid complexes. J. Am. Chem. Soc. 118, 5544-5552 (1996).
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 5544-5552
    • Tomac, S.1
  • 20
    • 0030035244 scopus 로고    scopus 로고
    • Enhanced peptide nucleic acid binding to supercoiled DNA: Possible implications for DNA "breathing" dynamics
    • Bentin, T. & Nielsen, P.E. Enhanced peptide nucleic acid binding to supercoiled DNA: possible implications for DNA "breathing" dynamics. Biochemistry 35, 8863-8869 (1996).
    • (1996) Biochemistry , vol.35 , pp. 8863-8869
    • Bentin, T.1    Nielsen, P.E.2
  • 21
    • 13044266375 scopus 로고    scopus 로고
    • Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood barrier and specifically reduce gene expression
    • Tyler, B.M. et al. Peptide nucleic acids targeted to the neurotensin receptor and administered i.p. cross the blood barrier and specifically reduce gene expression. Proc. Natl. Acad. Sci. USA 96, 7053-7058 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7053-7058
    • Tyler, B.M.1
  • 22
    • 0028960198 scopus 로고
    • Isolation of active genes containing CAG repeats after DNA strand invasion by Peptide Nucleic Acid
    • Boffa, L.C., Carpaneto, E.M. & Allfrey, V.G. Isolation of active genes containing CAG repeats after DNA strand invasion by Peptide Nucleic Acid. Proc. Natl. Acad. Sci. USA 92, 1901-1905 (1995).
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1901-1905
    • Boffa, L.C.1    Carpaneto, E.M.2    Allfrey, V.G.3
  • 23
    • 0029986009 scopus 로고    scopus 로고
    • Peptide Nucleic Acids (PNA): Synthesis, properties and potential applications
    • Hyrup, B. & Nielsen, P.E. Peptide Nucleic Acids (PNA): synthesis, properties and potential applications. Bioorg. Med. Chem. 4, 5-23 (1996).
    • (1996) Bioorg. Med. Chem. , vol.4 , pp. 5-23
    • Hyrup, B.1    Nielsen, P.E.2
  • 24
    • 0029978545 scopus 로고    scopus 로고
    • Apoptosis of Burkitt's Lymphoma cells induced by specific interaction surface IgM with a self-antigen: Implications for lymphomagenesis in acquired immunodeficiency syndrome
    • Roncella, S. et al. Apoptosis of Burkitt's Lymphoma cells induced by specific interaction surface IgM with a self-antigen: implications for lymphomagenesis in acquired immunodeficiency syndrome. Blood 88, 599-608 (1996).
    • (1996) Blood , vol.88 , pp. 599-608
    • Roncella, S.1
  • 25
    • 0343919897 scopus 로고    scopus 로고
    • Requirement for the CD95 receptor-ligand pathway in c-myc-induced apoptosis
    • Hueber, A.O. et al. Requirement for the CD95 receptor-ligand pathway in c-myc-induced apoptosis Science 278, 1205-1209 (1998).
    • (1998) Science , vol.278 , pp. 1205-1209
    • Hueber, A.O.1
  • 26
    • 0031754150 scopus 로고    scopus 로고
    • Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo
    • Pooga, M. et al. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol. 16, 856-861 (1998).
    • (1998) Nat. Biotechnol. , vol.16 , pp. 856-861
    • Pooga, M.1
  • 27
    • 0016822238 scopus 로고
    • Production by EBV infection of an EBNA-positive subline from an EBNA-negative human lymphoma cell line without detectable EBV DNA
    • Clemens, G.B., Klein, G. & Povery, S. Production by EBV infection of an EBNA-positive subline from an EBNA-negative human lymphoma cell line without detectable EBV DNA. Int. J. Cancer. 16, 125-133 (1975).
    • (1975) Int. J. Cancer , vol.16 , pp. 125-133
    • Clemens, G.B.1    Klein, G.2    Povery, S.3
  • 28
    • 0023852667 scopus 로고
    • Characterization and comparison of two newly established Epstein-Barr virus-negative lymphoma B-cell lines
    • H.
    • Abe, M., Nozawa, Y., Wakasa, H., Ohno & H., Fukuhara, S. Characterization and comparison of two newly established Epstein-Barr virus-negative lymphoma B-cell lines. Cancer 61, 483-490 (1988).
    • (1988) Cancer , vol.61 , pp. 483-490
    • Abe, M.1    Nozawa, Y.2    Wakasa, H.3    Ohno4    Fukuhara, S.5
  • 30
    • 0018252771 scopus 로고
    • Rapid hypotonic method for flow cytofluorometry of monolayer cell cultures
    • Freid, J., Perez, A.G. & Clarkson, B.D. Rapid hypotonic method for flow cytofluorometry of monolayer cell cultures. J. Histochem. Cytochem. 26, 921-933 (1978).
    • (1978) J. Histochem. Cytochem. , vol.26 , pp. 921-933
    • Freid, J.1    Perez, A.G.2    Clarkson, B.D.3
  • 31
    • 0004270170 scopus 로고
    • eds. Ausubel, F.M. et al. John Wiley & Sons, Boston, MA
    • Ausubel, F.M. et al. in Current protocols in molecular biology (eds. Ausubel, F.M. et al.) 1, 492-498 (John Wiley & Sons, Boston, MA, 1994).
    • (1994) Current Protocols in Molecular Biology , vol.1 , pp. 492-498
    • Ausubel, F.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.