Peptide nucleic acids (PNAs) with a functional backbone

Tetrahedron Letters

Volumn 39, Issue 26, 1998, Pages 4707-4710

  Püschl, Ask ^a   Sforza, Stefano ^b,c   Haaima, Gerald ^b,d   Dahl, Otto ^b   Nielsen, Peter E ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF PARMA   (Italy)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DNA; MONOMER; OLIGOMER; PEPTIDE NUCLEIC ACID; RNA;

ARTICLE; NUCLEIC ACID HYBRIDIZATION; NUCLEIC ACID STRUCTURE; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; SYNTHESIS; THERMOSTABILITY;

EID: 0032565941     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)00862-4     Document Type: Article

References (12)

1. 1. Nielsen, P. E.; Egholm, M.; Berg, R. H.; Buchardt, O. Science 1991, 254, 1497.
2. 2. Egholm, M.; Buchardt, O.; Nielsen, P. E.; Berg, R. H. J. Am. Chem. Soc. 1992, 114, 1895.
3. 3. Egholm, M.; Buchardt, O.; Nielsen, P. E.; Berg, R. H. J. Am. Chem. Soc. 1992, 114, 9677.
4. 4. Christensen, L.; Fitzpatrick, R.; Gildea, B.; Petersen, K. H.; Hansen, H. F.; Koch, T.; Egholm, M.; Buchardt, O.; Nielsen, P. E.; Coull, J.; Berg, R. H. J. Peptide Sci. 1995, 1, 175.
5. 5. Nielsen, P. E.; Haaima, G. Chem. Soc. Rev. 1997, 73.
6. 6. Dueholm, K. L.; Petersen, K. H.; Jensen, D. K.; Egholm, M.; Nielsen, P. E.; Buchardt, O. Bioorg. Med. Chem. Lett. 1994, 4, 1077.
7. 7. Haaima, G.; Lohse, A.; Buchardt, O.; Nielsen, P. E. Angew. Chem. Int. Ed. Engl. 1996, 35, 1939.
8. 8. Nielsen, P. E. Methods Enzymol. 1996, 267, 426.
9. 1H-NMR (major rotamer only): δ 11.29 (s, 1H), 7.34-7.19 (m, 6H), 6.55 (s, 1H), 4.58-4.45 (m, 2H), 4.16 (m, 1H), 3.40-2.60 (m, 6H), 1.76 (s, 3H), 1.33 (s, 9H).
10. 10. Brown, S. C.; Thomson, S. A.; Veal, J. M.; Davis, D. G. Science 1994, 265, 777.
11. 11. Eriksson, M.; Nielsen, P. E. Nature Struct. Biol. 1996, 3, 410.
12. 12. Rasmussen, H.; Kastrup, J. S.; Nielsen, J. N.; Nielsen, J. M.; Nielsen, P. E. Nature Struct. Biol. 1997, 4, 98.