Cyclohexanyl peptide nucleic acids (chPNAs) for preferential RNA binding: Effective tuning of dihedral angle β in PNAs for DNA/RNA discrimination

Journal of Organic Chemistry

Volumn 71, Issue 1, 2006, Pages 14-21

  Govindaraju, T ^a   Madhuri, V ^a   Kumar, Vaijayanti A ^a   Ganesh, Krishna N ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; DNA; POLYPEPTIDES; RNA; X RAY DIFFRACTION ANALYSIS;

BINDING SELECTIVITY; MELTING TEMPERATURES; PEPTIDE NUCLEIC ACIDS (PNA);

NUCLEIC ACIDS;

CYCLOHEXANE; CYCLOPENTANE; ETHYLENEDIAMINE; PEPTIDE NUCLEIC ACID;

ARTICLE; BETA CHAIN; BINDING AFFINITY; CHEMICAL MODIFICATION; DNA SEQUENCE; MELTING POINT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RNA BINDING; RNA SEQUENCE; ROENTGEN SPECTROSCOPY; STEREOCHEMISTRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DNA; MOLECULAR STRUCTURE; PEPTIDE NUCLEIC ACIDS; RNA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSITION TEMPERATURE;

EID: 31144445041     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo051227l     Document Type: Article

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