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Volumn 134, Issue 7, 2011, Pages 1882-1900

Enhancing remyelination in disease - Can we wrap it up?

Author keywords

multiple sclerosis; myelin; Neural stem cells; oligodendrocyte precursor cell; remyelination

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; HYALURONIC ACID; JAGGED1; MEMBRANE PROTEIN; NERVE CELL ADHESION MOLECULE; NOGGIN; NOTCH1 RECEPTOR; OSTEOGENIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; POLYSIALYLATED NERVE CELL ADHESION MOLECULE; PROTEIN LINGO 1; SEMAPHORIN 3A; SEMAPHORIN 3F; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 2; TRANSCRIPTION FACTOR NKX2.2; UNCLASSIFIED DRUG; WNT2 PROTEIN; WNT3A PROTEIN; WNT7A PROTEIN;

EID: 79959744924     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr014     Document Type: Review
Times cited : (147)

References (164)
  • 1
    • 0031911494 scopus 로고    scopus 로고
    • Intravenous immunoglobulin treatment in multiple sclerosis. Effect on relapses
    • Achiron A, Gabbay U, Gilad R, Hassin-Baer S, Barak Y, Gornish M, et al. Intravenous immunoglobulin treatment in multiple sclerosis. Effect on relapses. Neurology 1998; 50: 398-402.
    • (1998) Neurology , vol.50 , pp. 398-402
    • Achiron, A.1    Gabbay, U.2    Gilad, R.3    Hassin-Baer, S.4    Barak, Y.5    Gornish, M.6
  • 2
    • 78149481589 scopus 로고    scopus 로고
    • Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords
    • Androdias G, Reynolds R, Chanal M, Ritleng C, Confavreux C, Nataf S. Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords. Ann Neurol 2010; 68: 465-76.
    • (2010) Ann Neurol , vol.68 , pp. 465-476
    • Androdias, G.1    Reynolds, R.2    Chanal, M.3    Ritleng, C.4    Confavreux, C.5    Nataf, S.6
  • 3
    • 38049087759 scopus 로고    scopus 로고
    • Bone morphogenetic proteins 4, 6, and 7 are up-regulated in mouse spinal cord during experimental autoimmune encephalomyelitis
    • Ara J, See J, Mamontov P, Hahn A, Bannerman P, Pleasure D, et al. Bone morphogenetic proteins 4, 6, and 7 are up-regulated in mouse spinal cord during experimental autoimmune encephalomyelitis. J Neurosci Res 2008; 86: 125-35.
    • (2008) J Neurosci Res , vol.86 , pp. 125-135
    • Ara, J.1    See, J.2    Mamontov, P.3    Hahn, A.4    Bannerman, P.5    Pleasure, D.6
  • 5
    • 0242524481 scopus 로고    scopus 로고
    • Functional gen-omic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration
    • Arnett HA, Wang Y, Matsushima GK, Suzuki K, Ting JP. Functional gen-omic analysis of remyelination reveals importance of inflammation in oligodendrocyte regeneration. J Neurosci 2003; 23: 9824-32. (Pubitemid 37371596)
    • (2003) Journal of Neuroscience , vol.23 , Issue.30 , pp. 9824-9832
    • Arnett, H.A.1    Wang, Y.2    Matsushima, G.K.3    Suzuki, K.4    Ting, J.P.-Y.5
  • 7
    • 60149094000 scopus 로고    scopus 로고
    • Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling
    • Baer AS, Syed YA, Kang SU, Mitteregger D, Vig R, ffrench-Constant C, et al. Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain 2009; 132(Pt 2): 465-81.
    • (2009) Brain , vol.132 , Issue.PART 2 , pp. 465-481
    • Baer, A.S.1    Syed, Y.A.2    Kang, S.U.3    Mitteregger, D.4    Vig, R.5    Ffrench-Constant, C.6
  • 8
    • 0024841022 scopus 로고
    • Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development
    • DOI 10.1002/jnr.490240413
    • Bansal R, Warrington AE, Gard AL, Ranscht B, Pfeiffer SE. Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development. J Neurosci Res 1989; 24: 548-57. (Pubitemid 20015347)
    • (1989) Journal of Neuroscience Research , vol.24 , Issue.4 , pp. 548-557
    • Bansal, R.1    Warrington, A.E.2    Gard, A.L.3    Ranscht, B.4    Pfeiffer, S.E.5
  • 10
    • 0037437148 scopus 로고    scopus 로고
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    • DOI 10.1083/jcb.200210110
    • Belachew S, Chittajallu R, Aguirre AA, Yuan X, Kirby M, Anderson S, et al. Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons. J Cell Biol 2003; 161: 169-86. (Pubitemid 36459089)
    • (2003) Journal of Cell Biology , vol.161 , Issue.1 , pp. 169-186
    • Belachew, S.1    Chittajallu, R.2    Aguirre, A.A.3    Yuan, X.4    Kirby, M.5    Anderson, S.6    Gallo, V.7
  • 11
    • 0038077547 scopus 로고    scopus 로고
    • Efficient central nervous system remyelination requires T cells
    • DOI 10.1002/ana.10578
    • Bieber AJ, Kerr S, Rodriguez M. Efficient central nervous system remye-lination requires T cells. Ann Neurol 2003; 53: 680-4. (Pubitemid 36529446)
    • (2003) Annals of Neurology , vol.53 , Issue.5 , pp. 680-684
    • Bieber, A.J.1    Kerr, S.2    Rodriguez, M.3
  • 12
    • 0034070935 scopus 로고    scopus 로고
    • The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by αv integrins
    • Blaschuk KL, Frost EE, Ffrench-Constant C. The regulation of proliferation and differentiation in oligodendrocyte progenitor cells by alphaV in-tegrins. Development 2000; 127: 1961-9. (Pubitemid 30311799)
    • (2000) Development , vol.127 , Issue.9 , pp. 1961-1969
    • Blaschuk, K.L.1    Frost, E.E.2    Ffrench-Constant, C.3
  • 13
    • 0026582993 scopus 로고
    • TNF-alpha suppresses CR3-mediated myelin removal by macrophages
    • Bruck W, Bruck Y, Friede RL. TNF-alpha suppresses CR3-mediated myelin removal by macrophages. J Neuroimmunol 1992; 38: 9-17.
    • (1992) J Neuroimmunol , vol.38 , pp. 9-17
    • Bruck, W.1    Bruck, Y.2    Friede, R.L.3
  • 15
    • 0032861273 scopus 로고    scopus 로고
    • Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes
    • DOI 10.1006/mcne.1999.0781
    • Buttery PC, Ffrench-Constant C. Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes. Mol Cell Neurosci 1999; 14: 199-212. (Pubitemid 29449223)
    • (1999) Molecular and Cellular Neurosciences , vol.14 , Issue.3 , pp. 199-212
    • Buttery, P.C.1    Ffrench-Constant, C.2
  • 16
    • 33748432958 scopus 로고    scopus 로고
    • Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation
    • DOI 10.1016/j.expneurol.2006.04.030, PII S001448860600272X
    • Cassiani-Ingoni R, Coksaygan T, Xue H, Reichert-Scrivner SA, Wiendl H, Rao MS, et al. Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation. Exp Neurol 2006; 201: 349-58. (Pubitemid 44344228)
    • (2006) Experimental Neurology , vol.201 , Issue.2 , pp. 349-358
    • Cassiani-Ingoni, R.1    Coksaygan, T.2    Xue, H.3    Reichert-Scrivner, S.A.4    Wiendl, H.5    Rao, M.S.6    Magnus, T.7
  • 17
    • 0034281366 scopus 로고    scopus 로고
    • NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions
    • Chang A, Nishiyama A, Peterson J, Prineas J, Trapp BD. NG2-positive oligodendrocyte progenitor cells in adult human brain and multiple sclerosis lesions. J Neurosci 2000; 20: 6404-12.
    • (2000) J Neurosci , vol.20 , pp. 6404-6412
    • Chang, A.1    Nishiyama, A.2    Peterson, J.3    Prineas, J.4    Trapp, B.D.5
  • 18
    • 0037122960 scopus 로고    scopus 로고
    • Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis
    • DOI 10.1056/NEJMoa010994
    • Chang A, Tourtellotte WW, Rudick R, Trapp BD. Premyelinating oligo-dendrocytes in chronic lesions of multiple sclerosis. N Engl J Med 2002; 346: 165-73. (Pubitemid 34438882)
    • (2002) New England Journal of Medicine , vol.346 , Issue.3 , pp. 165-173
    • Chang, A.1    Tourtellotte, W.W.2    Rudick, R.3    Trapp, B.D.4
  • 19
    • 33644931322 scopus 로고    scopus 로고
    • Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system
    • DOI 10.1002/jnr.20763
    • Chari DM, Zhao C, Kotter MR, Blakemore WF, Franklin RJ. Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. J Neurosci Res 2006; 83: 594-605. (Pubitemid 43384853)
    • (2006) Journal of Neuroscience Research , vol.83 , Issue.4 , pp. 594-605
    • Chari, D.M.1    Zhao, C.2    Kotter, M.R.3    Blakemore, W.F.4    Franklin, R.J.M.5
  • 21
    • 0036723599 scopus 로고    scopus 로고
    • Re-expression of PSA-NCAM by demyelinated axons: An inhibitor of remyelination in multiple sclerosis?
    • Charles P, Reynolds R, Seilhean D, Rougon G, Aigrot MS, Niezgoda A, et al. Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis? Brain 2002; 125 (Pt 9): 1972-9.
    • (2002) Brain , vol.125 , Issue.PART 9 , pp. 1972-1979
    • Charles, P.1    Reynolds, R.2    Seilhean, D.3    Rougon, G.4    Aigrot, M.S.5    Niezgoda, A.6
  • 22
    • 58149165234 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor olig2 is critical for reactive astro-cyte proliferation after cortical injury
    • Chen Y, Miles DK, Hoang T, Shi J, Hurlock E, Kernie SG, et al. The basic helix-loop-helix transcription factor olig2 is critical for reactive astro-cyte proliferation after cortical injury. J Neurosci 2008; 28: 10983-9.
    • (2008) J Neurosci , vol.28 , pp. 10983-10989
    • Chen, Y.1    Miles, D.K.2    Hoang, T.3    Shi, J.4    Hurlock, E.5    Kernie, S.G.6
  • 23
    • 37349055151 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells
    • DOI 10.1634/stemcells.2007-0284
    • Cheng X, Wang Y, He Q, Qiu M, Whittemore SR, Cao Q. Bone mor-phogenetic protein signaling and olig1/2 interact to regulate the differentiation and maturation of adult oligodendrocyte precursor cells. Stem Cells 2007; 25: 3204-14. (Pubitemid 350294446)
    • (2007) Stem Cells , vol.25 , Issue.12 , pp. 3204-3214
    • Cheng, X.1    Wang, Y.2    He, Q.3    Qiu, M.4    Whittemore, S.R.5    Cao, Q.6
  • 24
    • 67449150167 scopus 로고    scopus 로고
    • A Wnt survival guide: From flies to human disease
    • Chien AJ, Conrad WH, Moon RT. A Wnt survival guide: from flies to human disease. J Invest Dermatol 2009; 129: 1614-27.
    • (2009) J Invest Dermatol , vol.129 , pp. 1614-1627
    • Chien, A.J.1    Conrad, W.H.2    Moon, R.T.3
  • 25
    • 0346732384 scopus 로고    scopus 로고
    • Antibody-mediated remyelination operates through mechanism independent of immunomodulation
    • DOI 10.1016/j.jneuroim.2003.11.002
    • Ciric B, Van KV, Paz SM, Rodriguez M, Pease LR. Antibody-mediated remyelination operates through mechanism independent of immuno-modulation. J Neuroimmunol 2004; 146: 153-61. (Pubitemid 38032967)
    • (2004) Journal of Neuroimmunology , vol.146 , Issue.1-2 , pp. 153-161
    • Ciric, B.1    Van Keulen, V.2    Paz Soldan, M.3    Rodriguez, M.4    Pease, L.R.5
  • 26
    • 0038240960 scopus 로고    scopus 로고
    • A role for semaphorins and neuropilins in oligodendrocyte guidance
    • DOI 10.1046/j.1471-4159.2003.01722.x
    • Cohen RI, Rottkamp DM, Maric D, Barker JL, Hudson LD. A role for semaphorins and neuropilins in oligodendrocyte guidance. J Neurochem 2003; 85: 1262-78. (Pubitemid 36613274)
    • (2003) Journal of Neurochemistry , vol.85 , Issue.5 , pp. 1262-1278
    • Cohen, R.I.1    Rottkamp, D.M.2    Maric, D.3    Barker, J.L.4    Hudson, L.D.5
  • 27
    • 7244247059 scopus 로고    scopus 로고
    • Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development
    • DOI 10.1083/jcb.200404076
    • Colognato H, Ramachandrappa S, Olsen IM, Ffrench-Constant C. Integrins direct Src family kinases to regulate distinct phases of oligo-dendrocyte development. J Cell Biol 2004; 167: 365-75. (Pubitemid 39435078)
    • (2004) Journal of Cell Biology , vol.167 , Issue.2 , pp. 365-375
    • Colognato, H.1    Ramachandrappa, S.2    Olsen, I.M.3    Ffrench-Constant, C.4
  • 28
    • 77957681466 scopus 로고    scopus 로고
    • Oestrogen receptor {beta} ligand: A novel treatment to enhance endogenous functional remyelination
    • Crawford DK, Mangiardi M, Song B, Patel R, Du S, Sofroniew MV, et al. Oestrogen receptor {beta} ligand: a novel treatment to enhance endogenous functional remyelination. Brain 2010; 133(Pt 10): 2999-3016.
    • (2010) Brain , vol.133 , Issue.PART 10 , pp. 2999-3016
    • Crawford, D.K.1    Mangiardi, M.2    Song, B.3    Patel, R.4    Du, S.5    Sofroniew, M.V.6
  • 31
    • 34250012532 scopus 로고    scopus 로고
    • Kip2 in the intracellular timer that controls oligodendrocyte differentiation
    • DOI 10.1523/JNEUROSCI.0628-07.2007
    • Dugas JC, Ibrahim A, Barres BA. A crucial role for p57(Kip2) in the intracellular timer that controls oligodendrocyte differentiation. J Neurosci 2007; 27: 6185-96. (Pubitemid 46890015)
    • (2007) Journal of Neuroscience , vol.27 , Issue.23 , pp. 6185-6196
    • Dugas, J.C.1    Ibrahim, A.2    Barres, B.A.3
  • 32
    • 7244226354 scopus 로고    scopus 로고
    • Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS
    • DOI 10.1016/j.mcn.2004.06.015, PII S1044743104001599
    • Fancy SP, Zhao C, Franklin RJM. Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Mol Cell Neurosci 2004; 27: 247-54. (Pubitemid 39433839)
    • (2004) Molecular and Cellular Neuroscience , vol.27 , Issue.3 , pp. 247-254
    • Fancy, S.P.J.1    Zhao, C.2    Franklin, R.J.M.3
  • 33
    • 67649655942 scopus 로고    scopus 로고
    • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
    • Fancy SPJ, Baranzini SE, Zhao C, Yuk D-I, Irvine K-A, Kaing S, et al. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev 2009; 23: 1571-85.
    • (2009) Genes Dev , vol.23 , pp. 1571-1585
    • Spj, F.1    Baranzini, S.E.2    Zhao, C.3    Yuk, D.-I.4    Irvine, K.-A.5    Kaing, S.6
  • 34
    • 0031057970 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of monthly intravenous immunoglobulin therapy in relapsing-remitting multiple sclerosis
    • DOI 10.1016/S0140-6736(96)09377-4
    • Fazekas F, Deisenhammer F, Strasser-Fuchs S, Nahler G, Mamoli B. Randomised placebo-controlled trial of monthly intravenous immuno-globulin therapy in relapsing-remitting multiple sclerosis. Austrian Immunoglobulin in Multiple Sclerosis Study Group. Lancet 1997; 349: 589-93. (Pubitemid 27101884)
    • (1997) Lancet , vol.349 , Issue.9052 , pp. 589-593
    • Fazekas, F.1    Deisenhammer, F.2    Strasser-Fuchs, S.3    Nahler, G.4    Mamoli, B.5
  • 35
    • 50549098795 scopus 로고    scopus 로고
    • Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: A dose-finding trial
    • Fazekas F, Lublin FD, Li D, Freedman MS, Hartung HP, Rieckmann P, et al. Intravenous immunoglobulin in relapsing-remitting multiple sclerosis: a dose-finding trial. Neurology 2008; 71: 265-71.
    • (2008) Neurology , vol.71 , pp. 265-271
    • Fazekas, F.1    Lublin, F.D.2    Li, D.3    Freedman, M.S.4    Hartung, H.P.5    Rieckmann, P.6
  • 36
    • 15044357461 scopus 로고    scopus 로고
    • Inflammation stimulates remyelination in areas of chronic demyelination
    • DOI 10.1093/brain/awh417
    • Foote AK, Blakemore WF. Inflammation stimulates remyelination in areas of chronic demyelination. Brain 2005; 128 (Pt 3): 528-39. (Pubitemid 40380188)
    • (2005) Brain , vol.128 , Issue.3 , pp. 528-539
    • Foote, A.K.1    Blakemore, W.F.2
  • 37
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • DOI 10.1038/nrn917
    • Franklin RJ. Why does remyelination fail in multiple sclerosis? Nat Rev Neurosci 2002; 3: 705-14. (Pubitemid 135706676)
    • (2002) Nature Reviews Neuroscience , vol.3 , Issue.9 , pp. 705-714
    • Franklin, R.J.M.1
  • 38
    • 0029163665 scopus 로고
    • Differentiation of the O-2A progenitor cell line CG-4 into oligodendro-cytes and astrocytes following transplantation into glia-deficient areas of CNS white matter
    • Franklin RJ, Bayley SA, Milner R, Ffrench-Constant C, Blakemore WF. Differentiation of the O-2A progenitor cell line CG-4 into oligodendro-cytes and astrocytes following transplantation into glia-deficient areas of CNS white matter. Glia 1995; 13: 39-44.
    • (1995) Glia , vol.13 , pp. 39-44
    • Franklin, R.J.1    Bayley, S.A.2    Milner, R.3    Ffrench-Constant, C.4    Blakemore, W.F.5
  • 39
    • 54249124952 scopus 로고    scopus 로고
    • Remyelination in the CNS: From biology to therapy
    • Franklin RJ, Ffrench-Constant C. Remyelination in the CNS: from biology to therapy. Nat Rev Neurosci 2008; 9: 839-55.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 839-855
    • Franklin, R.J.1    Ffrench-Constant, C.2
  • 40
    • 66549130329 scopus 로고    scopus 로고
    • The relation between inflammation and neuro-degeneration in multiple sclerosis brains
    • Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, et al. The relation between inflammation and neuro-degeneration in multiple sclerosis brains. Brain 2009; 132 (Pt 5): 1175-89.
    • (2009) Brain , vol.132 , Issue.PART 5 , pp. 1175-1189
    • Frischer, J.M.1    Bramow, S.2    Dal-Bianco, A.3    Lucchinetti, C.F.4    Rauschka, H.5    Schmidbauer, M.6
  • 41
    • 33644607018 scopus 로고    scopus 로고
    • Multiple sclerosis - The plaque and its pathogenesis
    • Frohman EM, Racke MK, Raine CS. Multiple sclerosis-the plaque and its pathogenesis. N Engl J Med 2006; 354: 942-55.
    • (2006) N Engl J Med , vol.354 , pp. 942-955
    • Frohman, E.M.1    Racke, M.K.2    Raine, C.S.3
  • 42
    • 0742272015 scopus 로고    scopus 로고
    • Negative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocytic differentiation pathway
    • DOI 10.1038/sj.cdd.4401332
    • Fukuda S, Kondo T, Takebayashi H, Taga T. Negative regulatory effect of an oligodendrocytic bHLH factor OLIG2 on the astrocytic differentiation pathway. Cell Death Differ 2004; 11: 196-202. (Pubitemid 38159643)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.2 , pp. 196-202
    • Fukuda, S.1    Kondo, T.2    Takebayashi, H.3    Taga, T.4
  • 44
    • 0344256592 scopus 로고    scopus 로고
    • Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro
    • DOI 10.1016/S0896-6273(03)00637-8
    • Gabay L, Lowell S, Rubin LL, Anderson DJ. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 2003; 40: 485-99. (Pubitemid 37494699)
    • (2003) Neuron , vol.40 , Issue.3 , pp. 485-499
    • Gabay, L.1    Lowell, S.2    Rubin, L.L.3    Anderson, D.J.4
  • 45
    • 0029044075 scopus 로고
    • Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein
    • Gard AL, Burrell MR, Pfeiffer SE, Rudge JS, Williams WC. Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein. Development 1995; 121: 2187-97.
    • (1995) Development , vol.121 , pp. 2187-2197
    • Gard, A.L.1    Burrell, M.R.2    Pfeiffer, S.E.3    Rudge, J.S.4    Williams, W.C.5
  • 46
    • 0033002020 scopus 로고    scopus 로고
    • Neurotransmitter receptor activation triggers p27(Kip1) and p21(CIP1) accumulation and G1 cell cycle arrest in oligodendrocyte progenitors
    • Ghiani CA, Eisen AM, Yuan X, DePinho RA, McBain CJ, Gallo V. Neurotransmitter receptor activation triggers p27(Kip1) and p21 (CIP1) accumulation and G1 cell cycle arrest in oligodendrocyte progenitors. Development 1999; 126: 1077-90. (Pubitemid 29142014)
    • (1999) Development , vol.126 , Issue.5 , pp. 1077-1090
    • Ghiani, C.A.1    Eisen, A.M.2    Yuan, X.3    DePinho, R.A.4    McBain, C.J.5    Gallo, V.6
  • 47
    • 0024460325 scopus 로고
    • In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice
    • Godfraind C, Friedrich VL, Holmes KV, Dubois-Dalcq M. In vivo analysis of glial cell phenotypes during a viral demyelinating disease in mice. J Cell Biol 1989; 109: 2405-16. (Pubitemid 19282625)
    • (1989) Journal of Cell Biology , vol.109 , Issue.5 , pp. 2405-2416
    • Godfraind, C.1    Friedrich, V.L.2    Holmes, K.V.3    Dubois-Dalcq, M.4
  • 48
    • 67650079567 scopus 로고    scopus 로고
    • Remyelination capacity of the MS brain decreases with disease chronicity
    • Goldschmidt T, Antel J, Konig FB, Bruck W, Kuhlmann T. Remyelination capacity of the MS brain decreases with disease chronicity. Neurology 2009; 72: 1914-21.
    • (2009) Neurology , vol.72 , pp. 1914-1921
    • Goldschmidt, T.1    Antel, J.2    Konig, F.B.3    Bruck, W.4    Kuhlmann, T.5
  • 49
    • 0037333616 scopus 로고    scopus 로고
    • Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment
    • DOI 10.1016/S0012-1606(02)00037-4
    • Gomes WA, Mehler MF, Kessler JA. Transgenic overexpression of BMP4 increases astroglial and decreases oligodendroglial lineage commitment. Dev Biol 2003; 255: 164-77. (Pubitemid 36287148)
    • (2003) Developmental Biology , vol.255 , Issue.1 , pp. 164-177
    • Gomes, W.A.1    Mehler, M.F.2    Kessler, J.A.3
  • 52
    • 0032968168 scopus 로고    scopus 로고
    • Tenascin-R and C in multiple sclerosis lesions: Relevance to extracellular matrix remodelling
    • DOI 10.1046/j.1365-2990.1999.00176.x
    • Gutowski NJ, Newcombe J, Cuzner ML. Tenascin-R and C in multiple sclerosis lesions: relevance to extracellular matrix remodelling. Neuropathol Appl Neurobiol 1999; 25: 207-14. (Pubitemid 29313225)
    • (1999) Neuropathology and Applied Neurobiology , vol.25 , Issue.3 , pp. 207-214
    • Gutowski, N.J.1    Newcombe, J.2    Cuzner, M.L.3
  • 53
    • 36248963140 scopus 로고    scopus 로고
    • A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo
    • DOI 10.1111/j.1460-9568.2007.05940.x
    • Hampton DW, Asher RA, Kondo T, Steeves JD, Ramer MS, Fawcett JW. A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo. Eur J Neurosci 2007; 26: 3024-35. (Pubitemid 350135185)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.11 , pp. 3024-3035
    • Hampton, D.W.1    Asher, R.A.2    Kondo, T.3    Steeves, J.D.4    Ramer, M.S.5    Fawcett, J.W.6
  • 54
    • 0032830744 scopus 로고    scopus 로고
    • Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-β1 gene expression during remyelination of experimentally-induced spinal cord demyelination
    • DOI 10.1006/mcne.1999.0771
    • Hinks GL, Franklin RJM. Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination. Mol Cell Neurosci 1999; 14: 153-68. (Pubitemid 29444885)
    • (1999) Molecular and Cellular Neurosciences , vol.14 , Issue.2 , pp. 153-168
    • Hinks, G.L.1    Franklin, R.J.M.2
  • 55
    • 0034530520 scopus 로고    scopus 로고
    • Delayed changes in growth factor gene expression during slow remyelination in the CNS of aged rats
    • DOI 10.1006/mcne.2000.0897
    • Hinks GL, Franklin RJM. Delayed changes in growth factor gene expression during slow remyelination in the CNS of aged rats. Mol Cell Neurosci 2000; 16: 542-56. (Pubitemid 32001304)
    • (2000) Molecular and Cellular Neuroscience , vol.16 , Issue.5 , pp. 542-556
    • Hinks, G.L.1    Franklin, R.J.M.2
  • 56
    • 4644250609 scopus 로고    scopus 로고
    • Intravenous immunoglobulin in secondary progressive multiple sclerosis: Randomised placebo-controlled trial
    • DOI 10.1016/S0140-6736(04)17101-8, PII S0140673604171018
    • Hommes OR, Sorensen PS, Fazekas F, Enriquez MM, Koelmel HW, Fernandez O, et al. Intravenous immunoglobulin in secondary progressive multiple sclerosis: randomised placebo-controlled trial. Lancet 2004; 364: 1149-56. (Pubitemid 39296602)
    • (2004) Lancet , vol.364 , Issue.9440 , pp. 1149-1156
    • Hommes, O.R.1    Sorensen, P.S.2    Fazekas, F.3    Enriquez, M.M.4    Koelmel, H.W.5    Fernandez, O.6    Pozzilli, C.7    O'Connor, P.8
  • 57
  • 58
    • 1642578925 scopus 로고    scopus 로고
    • Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody
    • DOI 10.1016/j.nbd.2003.09.002
    • Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimye-lin antibody. Neurobiol Dis 2004; 15: 120-31. (Pubitemid 38134387)
    • (2004) Neurobiology of Disease , vol.15 , Issue.1 , pp. 120-131
    • Howe, C.L.1    Bieber, A.J.2    Warrington, A.E.3    Pease, L.R.4    Rodriguez, M.5
  • 59
    • 0023712730 scopus 로고
    • Ciliary neuro-trophic factor induces type-2 astrocyte differentiation in culture
    • Hughes SM, Lillien LE, Raff MC, Rohrer H, Sendtner M. Ciliary neuro-trophic factor induces type-2 astrocyte differentiation in culture. Nature 1988; 335: 70-3.
    • (1988) Nature , vol.335 , pp. 70-3
    • Hughes, S.M.1    Lillien, L.E.2    Raff, M.C.3    Rohrer, H.4    Sendtner, M.5
  • 60
    • 75549087261 scopus 로고    scopus 로고
    • Emerging roles of Wnts in the adult nervous system
    • Inestrosa NC, Arenas E. Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci 2010; 11: 77-86.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 77-86
    • Inestrosa, N.C.1    Arenas, E.2
  • 61
    • 44949177395 scopus 로고    scopus 로고
    • Remyelination protects axons from demyelination-associated axon degeneration
    • DOI 10.1093/brain/awn080
    • Irvine KA, Blakemore WF. Remyelination protects axons from demyelination-associated axon degeneration. Brain 2008; 131(Pt 6): 1464-77. (Pubitemid 351806463)
    • (2008) Brain , vol.131 , Issue.6 , pp. 1464-1477
    • Irvine, K.A.1    Blakemore, W.F.2
  • 62
    • 62949121736 scopus 로고    scopus 로고
    • Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages
    • Ji JD, Park-Min KH, Ivashkiv LB. Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Hum Immunol 2009; 70: 211-7.
    • (2009) Hum Immunol , vol.70 , pp. 211-7
    • Ji, J.D.1    Park-Min, K.H.2    Ivashkiv, L.B.3
  • 63
    • 0036799650 scopus 로고    scopus 로고
    • Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
    • DOI 10.1038/nm781
    • John GR, Shankar SL, Shafit-Zagardo B, Massimi A, Lee SC, Raine CS, et al. Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat Med 2002; 8: 1115-21. (Pubitemid 35175966)
    • (2002) Nature Medicine , vol.8 , Issue.10 , pp. 1115-1121
    • John, G.R.1    Shankar, S.L.2    Shafit-Zagardo, B.3    Massimi, A.4    Lee, S.C.5    Raine, C.S.6    Brosnan, C.F.7
  • 64
    • 28444492982 scopus 로고    scopus 로고
    • Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis
    • DOI 10.1016/j.jneuroim.2005.10.013, PII S016557280500456X
    • Jurynczyk M, Jurewicz A, Bielecki B, Raine CS, Selmaj K. Inhibition of Notch signaling enhances tissue repair in an animal model of multiple sclerosis. J Neuroimmunol 2005; 170: 3-10. (Pubitemid 41740902)
    • (2005) Journal of Neuroimmunology , vol.170 , Issue.1-2 , pp. 3-10
    • Jurynczyk, M.1    Jurewicz, A.2    Bielecki, B.3    Raine, C.S.4    Selmaj, K.5
  • 65
    • 73349100648 scopus 로고    scopus 로고
    • Notch: A new player in MS mechanisms
    • Juryńczyk M, Selmaj K. Notch: a new player in MS mechanisms. J Neuroimmunol 2010; 218 :3-11.
    • (2010) J Neuroimmunol , vol.218 , pp. 3-11
    • Juryńczyk, M.1    Selmaj, K.2
  • 67
    • 70349769832 scopus 로고    scopus 로고
    • Actomyosin contractility controls cell surface area of oligodendrocytes
    • Kippert A, Fitzner D, Helenius J, Simons M. Actomyosin contractility controls cell surface area of oligodendrocytes. BMC Cell Biol 2009; 10: 71.
    • (2009) BMC Cell Biol , vol.10 , pp. 71
    • Kippert, A.1    Fitzner, D.2    Helenius, J.3    Simons, M.4
  • 68
    • 1242295301 scopus 로고    scopus 로고
    • A role for Noggin in the development of oligodendrocyte precursor cells
    • DOI 10.1016/j.ydbio.2003.11.013
    • Kondo T, Raff MC. A role for Noggin in the development of oligo-dendrocyte precursor cells. Dev Biol 2004; 267: 242-51. (Pubitemid 38234747)
    • (2004) Developmental Biology , vol.267 , Issue.1 , pp. 242-251
    • Kondo, T.1    Raff, M.C.2
  • 69
    • 30644476095 scopus 로고    scopus 로고
    • Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
    • DOI 10.1523/JNEUROSCI.2615-05.2006
    • Kotter MR, Li WW, Zhao C, Franklin RJM. Myelin impairs CNS remye-lination by inhibiting oligodendrocyte precursor cell differentiation. J Neurosci 2006; 26: 328-32. (Pubitemid 43089546)
    • (2006) Journal of Neuroscience , vol.26 , Issue.1 , pp. 328-332
    • Kotter, M.R.1    Li, W.-W.2    Zhao, C.3    Franklin, R.J.M.4
  • 70
    • 0034846364 scopus 로고    scopus 로고
    • Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination
    • DOI 10.1002/glia.1085
    • Kotter MR, Setzu A, Sim FJ, Van Rooijen N, Franklin RJM. Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination. Glia 2001; 35: 204-12. (Pubitemid 32827763)
    • (2001) GLIA , vol.35 , Issue.3 , pp. 204-212
    • Kotter, M.R.1    Setzu, A.2    Sim, F.J.3    Van Rooijen, N.4    Franklin, R.J.M.5
  • 71
    • 11844253894 scopus 로고    scopus 로고
    • Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
    • DOI 10.1016/j.nbd.2004.09.019, PII S0969996104002244
    • Kotter MR, Zhao C, Van Rooijen N, Franklin RJM. Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol Dis 2005; 18: 166-75. (Pubitemid 40092906)
    • (2005) Neurobiology of Disease , vol.18 , Issue.1 , pp. 166-175
    • Kotter, M.R.1    Zhao, C.2    Van Rooijen, N.3    Franklin, R.J.M.4
  • 72
    • 77957878657 scopus 로고    scopus 로고
    • Remyelination after cuprizone induced demyelination is accelerated in mice deficient in the polysialic acid synthesizing enzyme St8siaIV
    • Koutsoudaki PN, Hildebrandt H, Gudi V, Skripuletz T, Skuljec J, Stangel M. Remyelination after cuprizone induced demyelination is accelerated in mice deficient in the polysialic acid synthesizing enzyme St8siaIV. Neuroscience 2010.
    • (2010) Neuroscience
    • Koutsoudaki, P.N.1    Hildebrandt, H.2    Gudi, V.3    Skripuletz, T.4    Skuljec, J.5    Stangel, M.6
  • 73
    • 67049095584 scopus 로고    scopus 로고
    • P57kip2 is dynamically regulated in experimental autoimmune enceph-alomyelitis and interferes with oligodendroglial maturation
    • Kremer D, Heinen A, Jadasz J, Gottle P, Zimmermann K, Zickler P, et al. p57kip2 is dynamically regulated in experimental autoimmune enceph-alomyelitis and interferes with oligodendroglial maturation. Proc Natl Acad Sci USA 2009; 106: 9087-92.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9087-9092
    • Kremer, D.1    Heinen, A.2    Jadasz, J.3    Gottle, P.4    Zimmermann, K.5    Zickler, P.6
  • 74
    • 46849098585 scopus 로고    scopus 로고
    • Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis
    • DOI 10.1093/brain/awn096
    • Kuhlmann T, Miron V, Cuo Q, Wegner C, Antel J, Bruck W. Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis. Brain 2008; 131(Pt 7): 1749-58. (Pubitemid 351957453)
    • (2008) Brain , vol.131 , Issue.7 , pp. 1749-1758
    • Kuhlmann, T.1    Miron, V.2    Cuo, Q.3    Wegner, C.4    Antel, J.5    Bruck, W.6
  • 76
    • 0035096330 scopus 로고    scopus 로고
    • Heterogeneity of multiple sclerosis pathogenesis: Implications for diagnosis and therapy
    • DOI 10.1016/S1471-4914(00)01909-2, PII S1471491400019092
    • Lassmann H, Bruck W, Lucchinetti C. Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy. Trends Mol Med 2001; 7: 115-21. (Pubitemid 32201673)
    • (2001) Trends in Molecular Medicine , vol.7 , Issue.3 , pp. 115-121
    • Lassmann, H.1    Bruck, W.2    Lucchinetti, C.3
  • 77
    • 0032210917 scopus 로고    scopus 로고
    • Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve
    • DOI 10.1002/(SICI)1098-1136(199811) 24:3<329::AID-GLIA7>3.0.CO;2-X
    • Lazarov-Spiegler O, Solomon AS, Schwartz M. Peripheral nerve-stimulated macrophages simulate a peripheral nerve-like regenerative response in rat transected optic nerve. Glia 1998; 24: 329-37. (Pubitemid 28465980)
    • (1998) GLIA , vol.24 , Issue.3 , pp. 329-337
    • Lazarov-Spiegler, O.1    Solomon, A.S.2    Schwartz, M.3
  • 79
    • 0025351631 scopus 로고
    • Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development
    • Lillien LE, Sendtner M, Raff MC. Extracellular matrix-associated molecules collaborate with ciliary neurotrophic factor to induce type-2 astrocyte development. J Cell Biol 1990; 111: 635-44.
    • (1990) J Cell Biol , vol.111 , pp. 635-644
    • Lillien, L.E.1    Sendtner, M.2    Raff, M.C.3
  • 80
    • 34548638861 scopus 로고    scopus 로고
    • Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo
    • DOI 10.1111/j.1471-4159.2007.04756.x
    • Lingor P, Teusch N, Schwarz K, Mueller R, Mack H, Bahr M, et al. Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chon-droitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo. J Neurochem 2007; 103: 181-9. (Pubitemid 47404219)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.1 , pp. 181-189
    • Lingor, P.1    Teusch, N.2    Schwarz, K.3    Mueller, R.4    Mack, H.5    Bahr, M.6    Mueller, B.K.7
  • 81
    • 64949122507 scopus 로고    scopus 로고
    • Function of neurotrophic factors beyond the nervous system: Inflammation and autoimmune demyelination
    • Linker R, Gold R, Luhder F. Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination. Crit Rev Immunol 2009; 29: 43-68.
    • (2009) Crit Rev Immunol , vol.29 , pp. 43-68
    • Linker, R.1    Gold, R.2    Luhder, F.3
  • 83
    • 78049235500 scopus 로고    scopus 로고
    • Differentiation of neural precursor cell-derived oligodendrocyte progenitor cells following transplantation into normal and injured spinal cords
    • Lu HZ, Wang YX, Zou J, Li Y, Fu SL, Jin JQ, et al. Differentiation of neural precursor cell-derived oligodendrocyte progenitor cells following transplantation into normal and injured spinal cords. Differentiation 2010; 80: 228-40.
    • (2010) Differentiation , vol.80 , pp. 228-240
    • Lu, H.Z.1    Wang, Y.X.2    Zou, J.3    Li, Y.4    Fu, S.L.5    Jin, J.Q.6
  • 84
    • 0027027097 scopus 로고
    • Clonal segregation of oligodendrocytes and astrocytes during in vitro differentiation of glial progenitor cells
    • Lubetzki C, Goujet-Zalc C, Demerens C, Danos O, Zalc B. Clonal segregation of oligodendrocytes and astrocytes during in vitro differentiation of glial progenitor cells. Glia 1992; 6: 289-300.
    • (1992) Glia , vol.6 , pp. 289-300
    • Lubetzki, C.1    Goujet-Zalc, C.2    Demerens, C.3    Danos, O.4    Zalc, B.5
  • 85
    • 0345633543 scopus 로고    scopus 로고
    • A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases
    • Lucchinetti C, Bruck W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 113 cases. Brain 1999; 122 (Pt 12): 2279-95.
    • (1999) Brain , vol.122 , Issue.PART 12 , pp. 2279-2295
    • Lucchinetti, C.1    Bruck, W.2    Parisi, J.3    Scheithauer, B.4    Rodriguez, M.5    Lassmann, H.6
  • 86
    • 0030916680 scopus 로고    scopus 로고
    • Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial-astroglial progenitor cells
    • Mabie PC, Mehler MF, Marmur R, Papavasiliou A, Song Q, Kessler JA. Bone morphogenetic proteins induce astroglial differentiation of oligodendroglial- astroglial progenitor cells. J Neurosci 1997; 17: 4112-20. (Pubitemid 27220602)
    • (1997) Journal of Neuroscience , vol.17 , Issue.11 , pp. 4112-4120
    • Mabie, P.C.1    Mehler, M.F.2    Marmur, R.3    Papavasiliou, A.4    Song, Q.5    Kessler, J.A.6
  • 88
    • 0036897351 scopus 로고    scopus 로고
    • Histone deacetylase activity is necessary for oligodendrocyte lineage progression
    • Marin-Husstege M, Muggironi M, Liu A, Casaccia-Bonnefil P. Histone deacetylase activity is necessary for oligodendrocyte lineage progression. J Neurosci 2002; 22: 10333-45. (Pubitemid 35416871)
    • (2002) Journal of Neuroscience , vol.22 , Issue.23 , pp. 10333-10345
    • Marin-Husstege, M.1    Muggironi, M.2    Liu, A.3    Casaccia-Bonnefil, P.4
  • 89
    • 17444374900 scopus 로고    scopus 로고
    • Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones
    • DOI 10.1159/000082141
    • Marin-Husstege M, Muggironi M, Raban D, Skoff RP, Casaccia-Bonnefil P. Oligodendrocyte progenitor proliferation and maturation is differentially regulated by male and female sex steroid hormones. Dev Neurosci 2004; 26: 245-54. (Pubitemid 40867979)
    • (2004) Developmental Neuroscience , vol.26 , Issue.2-4 , pp. 245-254
    • Marin-Husstege, M.1    Muggironi, M.2    Raban, D.3    Skoff, R.P.4    Casaccia-Bonnefil, P.5
  • 91
    • 0042922772 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination
    • Mason JL, Xuan S, Dragatsis I, Efstratiadis A, Goldman JE. Insulin-like growth factor (IGF) signaling through type 1 IGF receptor plays an important role in remyelination. J Neurosci 2003; 23: 7710-8. (Pubitemid 37034089)
    • (2003) Journal of Neuroscience , vol.23 , Issue.20 , pp. 7710-7718
    • Mason, J.L.1    Xuan, S.2    Dragatsis, I.3    Efstratiadis, A.4    Goldman, J.E.5
  • 92
    • 0034255494 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination
    • Mason JL, Ye P, Suzuki K, D'Ercole AJ, Matsushima GK. Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination. J Neurosci 2000; 20: 5703-8. (Pubitemid 30636897)
    • (2000) Journal of Neuroscience , vol.20 , Issue.15 , pp. 5703-5708
    • Mason, J.L.1    Ye, P.2    Suzuki, K.3    D'Ercole, A.J.4    Matsushima, G.K.5
  • 93
    • 0025818938 scopus 로고
    • Insulin-like growth factor i (IGF-I) receptors and IGF-I action in oligodendrocytes from rat brains
    • Masters BA, Werner H, Roberts CT Jr, LeRoith D, Raizada MK. Insulin-like growth factor I (IGF-I) receptors and IGF-I action in oligodendrocytes from rat brains. Regul Pept 1991; 33: 117-31.
    • (1991) Regul Pept , vol.33 , pp. 117-131
    • Masters, B.A.1    Werner, H.2    Roberts Jr., C.T.3    Leroith, D.4    Raizada, M.K.5
  • 94
    • 0019313317 scopus 로고
    • Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue
    • DOI 10.1083/jcb.85.3.890
    • McCarthy KD, de Vellis J. Preparation of separate astroglial and oligo-dendroglial cell cultures from rat cerebral tissue. J Cell Biol 1980; 85: 890-902. (Pubitemid 10007455)
    • (1980) Journal of Cell Biology , vol.85 , Issue.3 , pp. 890-902
    • McCarthy, K.D.1    De Vellis, J.2
  • 95
    • 0036861534 scopus 로고    scopus 로고
    • Bone morphogenetic proteins negatively control oligodendrocyte precursor specification in the chick spinal cord
    • Mekki-Dauriac S, Agius E, Kan P, Cochard P. Bone morphogenetic proteins negatively control oligodendrocyte precursor specification in the chick spinal cord. Development 2002; 129: 5117-30. (Pubitemid 35460676)
    • (2002) Development , vol.129 , Issue.22 , pp. 5117-5130
    • Mekki-Dauriac, S.1    Agius, E.2    Kan, P.3    Cochard, P.4
  • 99
    • 65249142739 scopus 로고    scopus 로고
    • Promotion of central nervous system remyelination by induced differentiation of oligo-dendrocyte precursor cells
    • Mi S, Miller RH, Tang W, Lee X, Hu B, Wu W, et al. Promotion of central nervous system remyelination by induced differentiation of oligo-dendrocyte precursor cells. Ann Neurol 2009; 65: 304-15.
    • (2009) Ann Neurol , vol.65 , pp. 304-315
    • Mi, S.1    Miller, R.H.2    Tang, W.3    Lee, X.4    Hu, B.5    Wu, W.6
  • 100
    • 0030037331 scopus 로고    scopus 로고
    • Central nervous system remyelination clinical application of basic neuroscience principles
    • Miller DJ, Asakura K, Rodriguez M. Central nervous system remyelination clinical application of basic neuroscience principles. Brain Pathol 1996; 6: 331-44. (Pubitemid 26246387)
    • (1996) Brain Pathology , vol.6 , Issue.3 , pp. 331-344
    • Miller, D.J.1    Asakura, K.2    Rodriguez, M.3
  • 101
    • 35548986727 scopus 로고    scopus 로고
    • Dissecting demyelination
    • DOI 10.1038/nn1995, PII NN1995
    • Miller RH, Mi S. Dissecting demyelination. Nat Neurosci 2007; 10: 1351-4. (Pubitemid 350014684)
    • (2007) Nature Neuroscience , vol.10 , Issue.11 , pp. 1351-1354
    • Miller, R.H.1    Mi, S.2
  • 103
    • 2642539885 scopus 로고    scopus 로고
    • Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis
    • DOI 10.1016/j.clineuro.2004.02.019, PII S0303846704000459
    • Mycko MP, Papoian R, Boschert U, Raine CS, Selmaj KW. Microarray gene expression profiling of chronic active and inactive lesions in multiple sclerosis. Clin Neurol Neurosurg 2004; 106: 223-9. (Pubitemid 38716150)
    • (2004) Clinical Neurology and Neurosurgery , vol.106 , Issue.3 , pp. 223-229
    • Mycko, M.P.1    Papoian, R.2    Boschert, U.3    Raine, C.S.4    Selmaj, K.W.5
  • 104
    • 61749099508 scopus 로고    scopus 로고
    • Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligo-dendrocyte precursor cells in multiple sclerosis
    • Nakahara J, Kanekura K, Nawa M, Aiso S, Suzuki N. Abnormal expression of TIP30 and arrested nucleocytoplasmic transport within oligo-dendrocyte precursor cells in multiple sclerosis. J Clin Invest 2009; 119: 169-81.
    • (2009) J Clin Invest , vol.119 , pp. 169-181
    • Nakahara, J.1    Kanekura, K.2    Nawa, M.3    Aiso, S.4    Suzuki, N.5
  • 106
    • 60149098421 scopus 로고    scopus 로고
    • Debris clearance by microglia: An essential link between degeneration and regeneration
    • Neumann H, Kotter MR, Franklin RJM. Debris clearance by microglia: an essential link between degeneration and regeneration. Brain 2009; 132(Pt 2): 288-95.
    • (2009) Brain , vol.132 , Issue.PART 2 , pp. 288-295
    • Neumann, H.1    Kotter, M.R.2    Franklin, R.J.M.3
  • 108
    • 0036154986 scopus 로고    scopus 로고
    • Increasing local levels of IGF-I mRNA expression using adenoviral vectors does not alter oligodendrocyte remyelination in the CNS of aged rats
    • DOI 10.1006/mcne.2001.1062
    • O'Leary MT, Hinks GL, Franklin RJM. Increasing local levels of IGF-1 mRNA expression using adenoviral vectors does not alter oligodendro-cyte remyelination in the CNS of aged rats Charlton. Mol Cell Neurosci 2002; 19: 32-42. (Pubitemid 34113695)
    • (2002) Molecular and Cellular Neuroscience , vol.19 , Issue.1 , pp. 32-42
    • O'Leary, M.T.1    Hinks, G.L.2    Charlton, H.M.3    Franklin, R.J.M.4
  • 109
    • 0028578038 scopus 로고
    • Patterns of oligodendroglia pathology in multiple sclerosis
    • Ozawa K, Suchanek G, Breitschopf H, Bruck W, Budka H, Jellinger K, et al. Patterns of oligodendroglia pathology in multiple sclerosis. Brain 1994; 117 (Pt 6): 1311-22.
    • (1994) Brain , vol.117 , Issue.PART 6 , pp. 1311-1322
    • Ozawa, K.1    Suchanek, G.2    Breitschopf, H.3    Bruck, W.4    Budka, H.5    Jellinger, K.6
  • 110
    • 0023126661 scopus 로고
    • Exacerbations of multiple sclerosis in patients treated with gamma interferon
    • Panitch HS, Hirsch RL, Haley AS, Johnson KP. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1987; 1: 893-5.
    • (1987) Lancet , vol.1 , pp. 893-895
    • Panitch, H.S.1    Hirsch, R.L.2    Haley, A.S.3    Johnson, K.P.4
  • 111
    • 0032402062 scopus 로고    scopus 로고
    • Evidence for a role of the chemorepellent semaphorin III and its receptor neuropilin-1 in the regeneration of primary olfactory axons
    • Pasterkamp RJ, De Winter F, Holtmaat AJ, Verhaagen J. Evidence for a role of the chemorepellent semaphorin III and its receptor neuropilin-1 in the regeneration of primary olfactory axons. J Neurosci 1998; 18: 9962-76. (Pubitemid 28543772)
    • (1998) Journal of Neuroscience , vol.18 , Issue.23 , pp. 9962-9976
    • Pasterkamp, R.J.1    De Winter, F.2    Holtmaat, A.J.G.D.3    Verhaagen, J.4
  • 112
    • 34247862406 scopus 로고    scopus 로고
    • Remyelination can be extensive in multiple sclerosis despite a long disease course
    • DOI 10.1111/j.1365-2990.2007.00805.x
    • Patani R, Balaratnam M, Vora A, Reynolds R. Remyelination can be extensive in multiple sclerosis despite a long disease course. Neuropathol Appl Neurobiol 2007; 33: 277-87. (Pubitemid 46701044)
    • (2007) Neuropathology and Applied Neurobiology , vol.33 , Issue.3 , pp. 277-287
    • Patani, R.1    Balaratnam, M.2    Vora, A.3    Reynolds, R.4
  • 115
    • 0038692009 scopus 로고    scopus 로고
    • Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system
    • DOI 10.1093/brain/awg126
    • Penderis J, Shields SA, Franklin RJM. Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system. Brain 2003; 126(Pt 6): 1382-91. (Pubitemid 36644383)
    • (2003) Brain , vol.126 , Issue.6 , pp. 1382-1391
    • Penderis, J.1    Shields, S.A.2    Franklin, R.J.M.3
  • 116
    • 0027193569 scopus 로고
    • The oligodendrocyte and its many cellular processes
    • DOI 10.1016/0962-8924(93)90213-K
    • Pfeiffer SE, Warrington AE, Bansal R. The oligodendrocyte and its many cellular processes. Trends Cell Biol 1993; 3: 191-7. (Pubitemid 23156606)
    • (1993) Trends in Cell Biology , vol.3 , Issue.6 , pp. 191-197
    • Pfeiffer, S.E.1    Warrington, A.E.2    Bansal, R.3
  • 117
    • 0242468855 scopus 로고    scopus 로고
    • Notch signaling: A rheostat regulating oligodendrocyte differentiation?
    • DOI 10.1016/S1534-5807(03)00331-9, PII S1534580703003319
    • Popko B. Notch signaling: a rheostat regulating oligodendrocyte differentiation? Dev Cell 2003; 5: 668-9. (Pubitemid 37368853)
    • (2003) Developmental Cell , vol.5 , Issue.5 , pp. 668-669
    • Popko, B.1
  • 119
    • 0018410045 scopus 로고
    • Remyelination in multiple sclerosis
    • Prineas JW, Connell F. Remyelination in multiple sclerosis. Ann Neurol 1979; 5: 22-31. (Pubitemid 9083248)
    • (1979) Annals of Neurology , vol.5 , Issue.1 , pp. 22-31
    • Prineas, J.W.1    Connell, F.2
  • 122
    • 0035838420 scopus 로고    scopus 로고
    • Expression of dominant-negative and chimeric subunits reveals an essential role for β1 integrin during myelination
    • DOI 10.1016/S0960-9822(01)00292-5
    • Relvas JB, Setzu A, Baron W, Buttery PC, LaFlamme SE, Franklin RJM, et al. Expression of dominant-negative and chimeric subunits reveals an essential role for beta1 integrin during myelination. Curr Biol 2001; 11: 1039-43. (Pubitemid 32632718)
    • (2001) Current Biology , vol.11 , Issue.13 , pp. 1039-1043
    • Relvas, J.B.1    Setzu, A.2    Baron, W.3    Buttery, P.C.4    LaFlamme, S.E.5    Franklin, R.J.M.6    Ffrench-Constant, C.7
  • 123
    • 0035884808 scopus 로고    scopus 로고
    • Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): Coexistence with Ulip2/CRMP2 in Sema3A-sensitive oligodendrocytes
    • Ricard D, Rogemond V, Charrier E, Aguera M, Bagnard D, Belin MF, et al. Isolation and expression pattern of human Unc-33-like phospho-protein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes. J Neurosci 2001; 21: 7203-14. (Pubitemid 32846968)
    • (2001) Journal of Neuroscience , vol.21 , Issue.18 , pp. 7203-7214
    • Ricard, D.1    Rogemond, V.2    Charrier, E.3    Aguera, M.4    Bagnard, D.5    Belin, M.-F.6    Thomasset, N.7    Honnorat, J.8
  • 124
    • 56749156453 scopus 로고    scopus 로고
    • PDGFRA/NG2 glia generate myelinating oligodendrocytes and piri-form projection neurons in adult mice
    • Rivers LE, Young KM, Rizzi M, Jamen F, Psachoulia K, Wade A, et al. PDGFRA/NG2 glia generate myelinating oligodendrocytes and piri-form projection neurons in adult mice. Nat Neurosci 2008; 11: 1392-401.
    • (2008) Nat Neurosci , vol.11 , pp. 1392-401
    • Rivers, L.E.1    Young, K.M.2    Rizzi, M.3    Jamen, F.4    Psachoulia, K.5    Wade, A.6
  • 125
    • 0032713353 scopus 로고    scopus 로고
    • Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation
    • Robinson S, Miller RH. Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation. Dev Biol 1999; 216: 359-68.
    • (1999) Dev Biol , vol.216 , pp. 359-368
    • Robinson, S.1    Miller, R.H.2
  • 126
    • 70350763859 scopus 로고    scopus 로고
    • Effects of bone morphogenic proteins on neural precursor cells and regulation during central nervous system injury
    • Sabo JK, Kilpatrick TJ, Cate HS. Effects of bone morphogenic proteins on neural precursor cells and regulation during central nervous system injury. Neurosignals 2009; 17: 255-64.
    • (2009) Neurosignals , vol.17 , pp. 255-264
    • Sabo, J.K.1    Kilpatrick, T.J.2    Cate, H.S.3
  • 127
    • 4644223417 scopus 로고    scopus 로고
    • Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation
    • DOI 10.1242/dev.01273
    • Samanta J, Kessler JA. Interactions between ID and OLIG proteins mediate the inhibitory effects of BMP4 on oligodendroglial differentiation. Development 2004; 131: 4131-42. (Pubitemid 39276185)
    • (2004) Development , vol.131 , Issue.17 , pp. 4131-4142
    • Samanta, J.1    Kessler, J.A.2
  • 129
    • 33846510430 scopus 로고    scopus 로고
    • Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination
    • DOI 10.1007/s00401-006-0170-9
    • Seifert T, Bauer J, Weissert R, Fazekas F, Storch MK. Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination. Acta Neuropathol 2007; 113: 195-203. (Pubitemid 46158152)
    • (2007) Acta Neuropathologica , vol.113 , Issue.2 , pp. 195-203
    • Seifert, T.1    Bauer, J.2    Weissert, R.3    Fazekas, F.4    Storch, M.K.5
  • 130
    • 4644244652 scopus 로고    scopus 로고
    • Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation
    • DOI 10.1083/jcb.200404104
    • Setoguchi T, Kondo T. Nuclear export of OLIG2 in neural stem cells is essential for ciliary neurotrophic factor-induced astrocyte differentiation. J Cell Biol 2004; 166: 963-8. (Pubitemid 39304759)
    • (2004) Journal of Cell Biology , vol.166 , Issue.7 , pp. 963-968
    • Setoguchi, T.1    Kondo, T.2
  • 131
    • 22344446199 scopus 로고    scopus 로고
    • Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain
    • DOI 10.1083/jcb.200412101
    • Shen S, Li J, Casaccia-Bonnefil P. Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain. J Cell Biol 2005; 169: 577-89. (Pubitemid 41002851)
    • (2005) Journal of Cell Biology , vol.169 , Issue.4 , pp. 577-589
    • Shen, S.1    Li, J.2    Casaccia-Bonnefil, P.3
  • 132
    • 0033215282 scopus 로고    scopus 로고
    • Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination
    • DOI 10.1002/(SICI)1098-1136(199910) 28:1<77::AID-GLIA9>3.0.CO;2-F
    • Shields SA, Gilson JM, Blakemore WF, Franklin RJM. Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination. Glia 1999; 28: 77-83. (Pubitemid 29475582)
    • (1999) GLIA , vol.28 , Issue.1 , pp. 77-83
    • Shields, S.A.1    Gilson, J.M.2    Blakemore, W.F.3    Franklin, R.J.M.4
  • 133
    • 0036549138 scopus 로고    scopus 로고
    • The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation
    • Sim FJ, Zhao C, Penderis J, Franklin RJM. The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. J Neurosci 2002; 22: 2451-9. (Pubitemid 37465793)
    • (2002) Journal of Neuroscience , vol.22 , Issue.7 , pp. 2451-2459
    • Sim, F.J.1    Zhao, C.2    Penderis, J.3    Franklin, R.J.M.4
  • 134
    • 0028938139 scopus 로고
    • Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions
    • Sobel RA, Chen M, Maeda A, Hinojoza JR. Vitronectin and integrin vitronectin receptor localization in multiple sclerosis lesions. J Neuropathol Exp Neurol 1995; 54: 202-13.
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 202-213
    • Sobel, R.A.1    Chen, M.2    Maeda, A.3    Hinojoza, J.R.4
  • 137
    • 0036935588 scopus 로고    scopus 로고
    • Remyelinating strategies for the treatment of multiple sclerosis
    • DOI 10.1016/S0301-0082(02)00105-3, PII S0301008202001053
    • Stangel M, Hartung HP. Remyelinating strategies for the treatment of multiple sclerosis. Prog Neurobiol 2002; 68: 361-76. (Pubitemid 36071512)
    • (2002) Progress in Neurobiology , vol.68 , Issue.5 , pp. 361-376
    • Stangel, M.1    Hartung, H.-P.2
  • 138
    • 0030221564 scopus 로고    scopus 로고
    • News on glutamate receptors in glial cells
    • DOI 10.1016/0166-2236(96)10043-6
    • Steinhauser C, Gallo V. News on glutamate receptors in glial cells. Trends Neurosci 1996; 19: 339-45. (Pubitemid 26349063)
    • (1996) Trends in Neurosciences , vol.19 , Issue.8 , pp. 339-345
    • Steinhauser, C.1    Gallo, V.2
  • 139
    • 4344625746 scopus 로고    scopus 로고
    • Notch1 and jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination
    • DOI 10.1093/brain/awh217
    • Stidworthy MF, Genoud S, Li WW, Leone DP, Mantei N, Suter U, et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 2004; 127(Pt 9): 1928-41. (Pubitemid 39150252)
    • (2004) Brain , vol.127 , Issue.9 , pp. 1928-1941
    • Stidworthy, M.F.1    Genoud, S.2    Li, W.-W.3    Leone, D.P.4    Mantei, N.5    Suter, U.6    Franklin, R.J.M.7
  • 140
    • 0036794946 scopus 로고    scopus 로고
    • Extracellular and intracellular regulation of oligodendrocyte development: Roles of Sonic hedgehog and expression of E proteins
    • DOI 10.1002/glia.10114
    • Sussman CR, Davies JE, Miller RH. Extracellular and intracellular regulation of oligodendrocyte development: roles of Sonic hedgehog and expression of E proteins. Glia 2002; 40: 55-64. (Pubitemid 35181343)
    • (2002) GLIA , vol.40 , Issue.1 , pp. 55-64
    • Sussman, C.R.1    Davies, J.E.2    Miller, R.H.3
  • 141
  • 144
    • 33747186391 scopus 로고    scopus 로고
    • Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent
    • DOI 10.1002/glia.20369
    • Talbott JF, Cao Q, Enzmann GU, Benton RL, Achim V, Cheng XX, et al. Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent. Glia 2006; 54: 147-59. (Pubitemid 44230852)
    • (2006) GLIA , vol.54 , Issue.3 , pp. 147-159
    • Talbott, J.F.1    Cao, Q.2    Enzmann, G.U.3    Benton, R.L.4    Achim, V.5    Cheng, X.X.6    Mills, M.D.7    Rao, M.S.8    Whittemore, S.R.9
  • 148
    • 39549105606 scopus 로고    scopus 로고
    • Remyelination-promoting human IgMs: Developing a therapeutic reagent for demyelinating disease
    • Warrington AE, Rodriguez M. Remyelination-promoting human IgMs: developing a therapeutic reagent for demyelinating disease. Curr Top Microbiol Immunol 2008; 318: 213-39.
    • (2008) Curr Top Microbiol Immunol , vol.318 , pp. 213-239
    • Warrington, A.E.1    Rodriguez, M.2
  • 150
    • 0031962240 scopus 로고    scopus 로고
    • Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells
    • Wolswijk G. Chronic stage multiple sclerosis lesions contain a relatively quiescent population of oligodendrocyte precursor cells. J Neurosci 1998; 18: 601-9. (Pubitemid 28041896)
    • (1998) Journal of Neuroscience , vol.18 , Issue.2 , pp. 601-609
    • Wolswijk, G.1
  • 151
    • 0033962548 scopus 로고    scopus 로고
    • Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis
    • Wolswijk G. Oligodendrocyte survival, loss and birth in lesions of chronic-stage multiple sclerosis. Brain 2000; 123(Pt 1): 105-15. (Pubitemid 30037973)
    • (2000) Brain , vol.123 , Issue.1 , pp. 105-115
    • Wolswijk, G.1
  • 152
    • 0036158610 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord
    • Wolswijk G. Oligodendrocyte precursor cells in the demyelinated multiple sclerosis spinal cord. Brain 2002; 125(Pt 2): 338-49. (Pubitemid 34127436)
    • (2002) Brain , vol.125 , Issue.2 , pp. 338-349
    • Wolswijk, G.1
  • 153
    • 0036897583 scopus 로고    scopus 로고
    • NTR and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein
    • DOI 10.1038/nn975
    • Wong ST, Henley JR, Kanning KC, Huang KH, Bothwell M, Poo MM. A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein. Nat Neurosci 2002; 5: 1302-8. (Pubitemid 35417765)
    • (2002) Nature Neuroscience , vol.5 , Issue.12 , pp. 1302-1308
    • Wong, S.T.1    Henley, J.R.2    Kanning, K.C.3    Huang, K.-H.4    Bothwell, M.5    Poo, M.-M.6
  • 154
    • 0032967144 scopus 로고    scopus 로고
    • The expression of myelin protein mRNAs during remyelination of lysolecithin-induced demyelination
    • DOI 10.1046/j.1365-2990.1999.00172.x
    • Woodruff RH, Franklin RJM. The expression of myelin protein mRNAs during remyelination of lysolecithin-induced demyelination. Neuropathol Appl Neurobiol 1999; 25: 226-35. (Pubitemid 29313227)
    • (1999) Neuropathology and Applied Neurobiology , vol.25 , Issue.3 , pp. 226-235
    • Woodruff, R.H.1    Franklin, R.J.M.2
  • 155
    • 1542425338 scopus 로고    scopus 로고
    • Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelination
    • DOI 10.1016/j.mcn.2003.10.014, PII S1044743103003361
    • Woodruff RA, Fruttiger M, Richardson WD, Franklin RJM. Platelet-derived growth factor regulates oligodendrocyte progenitor numbers in adult CNS and their response following CNS demyelin-ation. Mol Cell Neurosci 2004; 25: 252-62. (Pubitemid 38344108)
    • (2004) Molecular and Cellular Neuroscience , vol.25 , Issue.2 , pp. 252-262
    • Woodruff, R.H.1    Fruttiger, M.2    Richardson, W.D.3    Franklin, R.J.M.4
  • 156
    • 73549115379 scopus 로고    scopus 로고
    • Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies
    • Wright BR, Warrington AE, Edberg DD, Rodriguez M. Cellular mechanisms of central nervous system repair by natural autoreactive monoclonal antibodies. Arch Neurol 2009; 66: 1456-9.
    • (2009) Arch Neurol , vol.66 , pp. 1456-1459
    • Wright, B.R.1    Warrington, A.E.2    Edberg, D.D.3    Rodriguez, M.4
  • 157
    • 0033305581 scopus 로고    scopus 로고
    • Insulin-like growth factor I protects oligodendrocytes from tumor necrosis factor-α-induced injury
    • Ye P, D'Ercole AJ. Insulin-like growth factor I protects oligodendrocytes from tumor necrosis factor-alpha-induced injury. Endocrinology 1999; 140: 3063-72. (Pubitemid 30650620)
    • (1999) Endocrinology , vol.140 , Issue.7 , pp. 3063-3072
    • Ye, P.1    D'Ercole, A.J.2
  • 158
    • 77952571743 scopus 로고    scopus 로고
    • An Fgfr3-iCreER(T2) transgenic mouse line for studies of neural stem cells and astrocytes
    • Young KM, Mitsumori T, Pringle N, Grist M, Kessaris N, Richardson WD. An Fgfr3-iCreER(T2) transgenic mouse line for studies of neural stem cells and astrocytes. Glia 2010; 58: 943-53.
    • (2010) Glia , vol.58 , pp. 943-953
    • Young, K.M.1    Mitsumori, T.2    Pringle, N.3    Grist, M.4    Kessaris, N.5    Richardson, W.D.6
  • 159
    • 77956633377 scopus 로고    scopus 로고
    • CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination
    • Zawadzka M, Rivers LE, Fancy SP, Zhao C, Tripathi R, Jamen F, et al. CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell 2009; 6: 578-90.
    • (2009) Cell Stem Cell , vol.6 , pp. 578-590
    • Zawadzka, M.1    Rivers, L.E.2    Fancy, S.P.3    Zhao, C.4    Tripathi, R.5    Jamen, F.6
  • 160
    • 73149124029 scopus 로고    scopus 로고
    • Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination
    • Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, et al. Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci USA 2009; 106: 19162-7.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 19162-19167
    • Zhang, Y.1    Argaw, A.T.2    Gurfein, B.T.3    Zameer, A.4    Snyder, B.J.5    Ge, C.6
  • 161
    • 2042463364 scopus 로고    scopus 로고
    • Comparison of in vivo and in vitro subcellular localization of estrogen receptors α and β in oligodendrocytes
    • Zhang Z, Cerghet M, Mullins C, Williamson M, Bessert D, Skoff R. Comparison of in vivo and in vitro subcellular localization of estrogen receptors alpha and beta in oligodendrocytes. J Neurochem 2004; 89: 674-84. (Pubitemid 38534153)
    • (2004) Journal of Neurochemistry , vol.89 , Issue.3 , pp. 674-684
    • Zhang, Z.1    Cerghet, M.2    Mullins, C.3    Williamson, M.4    Bessert, D.5    Skoff, R.6
  • 162
    • 41549099965 scopus 로고    scopus 로고
    • Semaphorin signaling: Progress made and promises ahead
    • Zhou Y, Gunput RA, Pasterkamp RJ. Semaphorin signaling: progress made and promises ahead. Trends Biochem Sci 2008; 33: 161-70.
    • (2008) Trends Biochem Sci , vol.33 , pp. 161-170
    • Zhou, Y.1    Gunput, R.A.2    Pasterkamp, R.J.3
  • 163
    • 38849095193 scopus 로고    scopus 로고
    • NG2 cells generate both oligodendrocytes and gray matter astrocytes
    • DOI 10.1242/dev.004895
    • Zhu X, Bergles DE, Nishiyama A. NG2 cells generate both oligo-dendrocytes and gray matter astrocytes. Development 2008a; 135: 145-57. (Pubitemid 351201488)
    • (2008) Development , vol.135 , Issue.1 , pp. 145-157
    • Zhu, X.1    Bergles, D.E.2    Nishiyama, A.3
  • 164
    • 64549125545 scopus 로고    scopus 로고
    • NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord
    • Zhu X, Hill RA, Nishiyama A. NG2 cells generate oligodendrocytes and gray matter astrocytes in the spinal cord. Neuron Glia Biol 2008b; 4: 19-26.
    • (2008) Neuron Glia Biol , vol.4 , pp. 19-26
    • Zhu, X.1    Hill, R.A.2    Nishiyama, A.3


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