메뉴 건너뛰기




Volumn 6, Issue 6, 2010, Pages 578-590

CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2;

EID: 77956633377     PISSN: 19345909     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.stem.2010.04.002     Document Type: Article
Times cited : (501)

References (59)
  • 3
    • 0037437148 scopus 로고    scopus 로고
    • Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons
    • S. Belachew, R. Chittajallu, A.A. Aguirre, X. Yuan, M. Kirby, S. Anderson, and V. Gallo Postnatal NG2 proteoglycan-expressing progenitor cells are intrinsically multipotent and generate functional neurons J. Cell Biol. 161 2003 169 186
    • (2003) J. Cell Biol. , vol.161 , pp. 169-186
    • Belachew, S.1    Chittajallu, R.2    Aguirre, A.A.3    Yuan, X.4    Kirby, M.5    Anderson, S.6    Gallo, V.7
  • 4
    • 0016774107 scopus 로고
    • Remyelination by Schwann cells of axons demyelinated by intraspinal injection of 6-aminonicotinamide in the rat
    • W.F. Blakemore Remyelination by Schwann cells of axons demyelinated by intraspinal injection of 6-aminonicotinamide in the rat J. Neurocytol. 4 1975 745 757
    • (1975) J. Neurocytol. , vol.4 , pp. 745-757
    • Blakemore, W.F.1
  • 5
    • 39549095800 scopus 로고    scopus 로고
    • Remyelination in experimental models of toxin-induced demyelination
    • W.F. Blakemore, and R.J.M. Franklin Remyelination in experimental models of toxin-induced demyelination Curr. Top. Microbiol. Immunol. 318 2008 193 212
    • (2008) Curr. Top. Microbiol. Immunol. , vol.318 , pp. 193-212
    • Blakemore, W.F.1    Franklin, R.J.M.2
  • 7
    • 33748432958 scopus 로고    scopus 로고
    • Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation
    • R. Cassiani-Ingoni, T. Coksaygan, H. Xue, S.A. Reichert-Scrivner, H. Wiendl, M.S. Rao, and T. Magnus Cytoplasmic translocation of Olig2 in adult glial progenitors marks the generation of reactive astrocytes following autoimmune inflammation Exp. Neurol. 201 2006 349 358
    • (2006) Exp. Neurol. , vol.201 , pp. 349-358
    • Cassiani-Ingoni, R.1    Coksaygan, T.2    Xue, H.3    Reichert-Scrivner, S.A.4    Wiendl, H.5    Rao, M.S.6    Magnus, T.7
  • 8
    • 0014783392 scopus 로고
    • The proliferation of astrocytes around a needle wound in the rat brain
    • J.B. Cavanagh The proliferation of astrocytes around a needle wound in the rat brain J. Anat. 106 1970 471 487
    • (1970) J. Anat. , vol.106 , pp. 471-487
    • Cavanagh, J.B.1
  • 9
    • 4644305940 scopus 로고    scopus 로고
    • Differential generation of oligodendrocytes from human and rodent embryonic spinal cord neural precursors
    • S. Chandran, A. Compston, E. Jauniaux, J. Gilson, W. Blakemore, and C. Svendsen Differential generation of oligodendrocytes from human and rodent embryonic spinal cord neural precursors Glia 47 2004 314 324
    • (2004) Glia , vol.47 , pp. 314-324
    • Chandran, S.1    Compston, A.2    Jauniaux, E.3    Gilson, J.4    Blakemore, W.5    Svendsen, C.6
  • 10
    • 58149165234 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury
    • Y. Chen, D.K. Miles, T. Hoang, J. Shi, E. Hurlock, S.G. Kernie, and Q.R. Lu The basic helix-loop-helix transcription factor olig2 is critical for reactive astrocyte proliferation after cortical injury J. Neurosci. 28 2008 10983 10989
    • (2008) J. Neurosci. , vol.28 , pp. 10983-10989
    • Chen, Y.1    Miles, D.K.2    Hoang, T.3    Shi, J.4    Hurlock, E.5    Kernie, S.G.6    Lu, Q.R.7
  • 11
    • 4143102903 scopus 로고    scopus 로고
    • The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS
    • A.J. Crang, J.M. Gilson, W.W. Li, and W.F. Blakemore The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS Eur. J. Neurosci. 20 2004 1445 1460
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1445-1460
    • Crang, A.J.1    Gilson, J.M.2    Li, W.W.3    Blakemore, W.F.4
  • 13
    • 55249102238 scopus 로고    scopus 로고
    • Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex
    • L. Dimou, C. Simon, F. Kirchhoff, H. Takebayashi, and M. Götz Progeny of Olig2-expressing progenitors in the gray and white matter of the adult mouse cerebral cortex J. Neurosci. 28 2008 10434 10442
    • (2008) J. Neurosci. , vol.28 , pp. 10434-10442
    • Dimou, L.1    Simon, C.2    Kirchhoff, F.3    Takebayashi, H.4    Götz, M.5
  • 14
    • 0031033590 scopus 로고    scopus 로고
    • Schwann cell invasion of the central nervous system of the myelin mutants
    • I.D. Duncan, and R.L. Hoffman Schwann cell invasion of the central nervous system of the myelin mutants J. Anat. 190 1997 35 49
    • (1997) J. Anat. , vol.190 , pp. 35-49
    • Duncan, I.D.1    Hoffman, R.L.2
  • 15
    • 0026483307 scopus 로고
    • Demyelination and remyelination by Schwann cells and oligodendrocytes after kainate-induced neuronal depletion in the central nervous system
    • I. Dusart, S. Marty, and M. Peschanski Demyelination and remyelination by Schwann cells and oligodendrocytes after kainate-induced neuronal depletion in the central nervous system Neuroscience 5 1992 137 148
    • (1992) Neuroscience , vol.5 , pp. 137-148
    • Dusart, I.1    Marty, S.2    Peschanski, M.3
  • 16
    • 7244226354 scopus 로고    scopus 로고
    • Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS
    • S.P.J. Fancy, C. Zhao, and R.J.M. Franklin Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS Mol. Cell. Neurosci. 27 2004 247 254
    • (2004) Mol. Cell. Neurosci. , vol.27 , pp. 247-254
    • Fancy, S.P.J.1    Zhao, C.2    Franklin, R.J.M.3
  • 17
    • 21944442728 scopus 로고    scopus 로고
    • Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide
    • P.A. Felts, A.M. Woolston, H.B. Fernando, S. Asquith, N.A. Gregson, O.J. Mizzi, and K.J. Smith Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide Brain 128 2005 1649 1666
    • (2005) Brain , vol.128 , pp. 1649-1666
    • Felts, P.A.1    Woolston, A.M.2    Fernando, H.B.3    Asquith, S.4    Gregson, N.A.5    Mizzi, O.J.6    Smith, K.J.7
  • 18
    • 0027495887 scopus 로고
    • Requirements for Schwann cell migration within CNS environments: A viewpoint
    • R.J.M. Franklin, and W.F. Blakemore Requirements for Schwann cell migration within CNS environments: A viewpoint Int. J. Dev. Neurosci. 11 1993 641 649
    • (1993) Int. J. Dev. Neurosci. , vol.11 , pp. 641-649
    • Franklin, R.J.M.1    Blakemore, W.F.2
  • 20
    • 0030861649 scopus 로고    scopus 로고
    • Endogenous progenitors remyelinate demyelinated axons in the adult CNS
    • J.M. Gensert, and J.E. Goldman Endogenous progenitors remyelinate demyelinated axons in the adult CNS Neuron 19 1997 197 203
    • (1997) Neuron , vol.19 , pp. 197-203
    • Gensert, J.M.1    Goldman, J.E.2
  • 21
    • 0028204901 scopus 로고
    • Periaxin, a novel protein of myelinating Schwann cells with a possible role in axonal ensheathment
    • C.S. Gillespie, D.L. Sherman, G.E. Blair, and P.J. Brophy Periaxin, a novel protein of myelinating Schwann cells with a possible role in axonal ensheathment Neuron 12 1994 497 508
    • (1994) Neuron , vol.12 , pp. 497-508
    • Gillespie, C.S.1    Sherman, D.L.2    Blair, G.E.3    Brophy, P.J.4
  • 22
    • 0142109173 scopus 로고    scopus 로고
    • Schwann-like macroglia in adult rat brain
    • G. Gudiño-Cabrera, and M. Nieto-Sampedro Schwann-like macroglia in adult rat brain Glia 30 2000 49 63
    • (2000) Glia , vol.30 , pp. 49-63
    • Gudiño-Cabrera, G.1    Nieto-Sampedro, M.2
  • 23
    • 0020516765 scopus 로고
    • Schwann cell remyelination of demyelinated axons in spinal cord multiple sclerosis lesions
    • Y. Itoyama, H.D. Webster, E.P. Richardson Jr., and B.D. Trapp Schwann cell remyelination of demyelinated axons in spinal cord multiple sclerosis lesions Ann. Neurol. 14 1983 339 346
    • (1983) Ann. Neurol. , vol.14 , pp. 339-346
    • Itoyama, Y.1    Webster, H.D.2    Richardson Jr., E.P.3    Trapp, B.D.4
  • 24
    • 0021968643 scopus 로고
    • Spinal cord multiple sclerosis lesions in Japanese patients: Schwann cell remyelination occurs in areas that lack glial fibrillary acidic protein (GFAP)
    • Y. Itoyama, A. Ohnishi, J. Tateishi, Y. Kuroiwa, and H.D. Webster Spinal cord multiple sclerosis lesions in Japanese patients: Schwann cell remyelination occurs in areas that lack glial fibrillary acidic protein (GFAP) Acta Neuropathol. 65 1985 217 223
    • (1985) Acta Neuropathol. , vol.65 , pp. 217-223
    • Itoyama, Y.1    Ohnishi, A.2    Tateishi, J.3    Kuroiwa, Y.4    Webster, H.D.5
  • 25
    • 0030785547 scopus 로고    scopus 로고
    • Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord
    • H.S. Keirstead, and W.F. Blakemore Identification of post-mitotic oligodendrocytes incapable of remyelination within the demyelinated adult spinal cord J. Neuropathol. Exp. Neurol. 56 1997 1191 1201
    • (1997) J. Neuropathol. Exp. Neurol. , vol.56 , pp. 1191-1201
    • Keirstead, H.S.1    Blakemore, W.F.2
  • 26
    • 0033198197 scopus 로고    scopus 로고
    • Polysialylated neural cell adhesion molecule-positive CNS precursors generate both oligodendrocytes and Schwann cells to remyelinate the CNS after transplantation
    • H.S. Keirstead, T. Ben-Hur, B. Rogister, M.T. O'Leary, M. Dubois-Dalcq, and W.F. Blakemore Polysialylated neural cell adhesion molecule-positive CNS precursors generate both oligodendrocytes and Schwann cells to remyelinate the CNS after transplantation J. Neurosci. 19 1999 7529 7536
    • (1999) J. Neurosci. , vol.19 , pp. 7529-7536
    • Keirstead, H.S.1    Ben-Hur, T.2    Rogister, B.3    O'Leary, M.T.4    Dubois-Dalcq, M.5    Blakemore, W.F.6
  • 27
    • 31544442467 scopus 로고    scopus 로고
    • Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage
    • N. Kessaris, M. Fogarty, P. Iannarelli, M. Grist, M. Wegner, and W.D. Richardson Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage Nat. Neurosci. 9 2006 173 179
    • (2006) Nat. Neurosci. , vol.9 , pp. 173-179
    • Kessaris, N.1    Fogarty, M.2    Iannarelli, P.3    Grist, M.4    Wegner, M.5    Richardson, W.D.6
  • 28
    • 0034622930 scopus 로고    scopus 로고
    • Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells
    • T. Kondo, and M. Raff Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells Science 289 2000 1754 1757
    • (2000) Science , vol.289 , pp. 1754-1757
    • Kondo, T.1    Raff, M.2
  • 29
    • 1242295301 scopus 로고    scopus 로고
    • A role for Noggin in the development of oligodendrocyte precursor cells
    • T. Kondo, and M.C. Raff A role for Noggin in the development of oligodendrocyte precursor cells Dev. Biol. 267 2004 242 251
    • (2004) Dev. Biol. , vol.267 , pp. 242-251
    • Kondo, T.1    Raff, M.C.2
  • 30
    • 0030642178 scopus 로고    scopus 로고
    • P0 is constitutively expressed in the rat neural crest and embryonic nerves and is negatively and positively regulated by axons to generate non-myelin-forming and myelin-forming Schwann cells, respectively
    • M.J. Lee, A. Brennan, A. Blanchard, G. Zoidl, Z. Dong, A. Tabernero, C. Zoidl, M.A.R. Dent, K.R. Jessen, and R. Mirsky P0 is constitutively expressed in the rat neural crest and embryonic nerves and is negatively and positively regulated by axons to generate non-myelin-forming and myelin-forming Schwann cells, respectively Mol. Cell. Neurosci. 8 1997 336 350
    • (1997) Mol. Cell. Neurosci. , vol.8 , pp. 336-350
    • Lee, M.J.1    Brennan, A.2    Blanchard, A.3    Zoidl, G.4    Dong, Z.5    Tabernero, A.6    Zoidl, C.7    Dent, M.A.R.8    Jessen, K.R.9    Mirsky, R.10
  • 32
    • 0027405346 scopus 로고
    • Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain
    • S.W. Levison, and J.E. Goldman Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain Neuron 10 1993 201 212
    • (1993) Neuron , vol.10 , pp. 201-212
    • Levison, S.W.1    Goldman, J.E.2
  • 35
    • 33646198141 scopus 로고    scopus 로고
    • Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
    • N. Masahira, H. Takebayashi, K. Ono, K. Watanabe, L. Ding, M. Furusho, Y. Ogawa, Y. Nabeshima, A. Alvarez-Buylla, K. Shimizu, and K. Ikenaka Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells Dev. Biol. 293 2006 358 369
    • (2006) Dev. Biol. , vol.293 , pp. 358-369
    • Masahira, N.1    Takebayashi, H.2    Ono, K.3    Watanabe, K.4    Ding, L.5    Furusho, M.6    Ogawa, Y.7    Nabeshima, Y.8    Alvarez-Buylla, A.9    Shimizu, K.10    Ikenaka, K.11
  • 36
    • 0032146443 scopus 로고    scopus 로고
    • A common neural progenitor for the CNS and PNS
    • T. Mujtaba, M. Mayer-Proschel, and M.S. Rao A common neural progenitor for the CNS and PNS Dev. Biol. 200 1998 1 15
    • (1998) Dev. Biol. , vol.200 , pp. 1-15
    • Mujtaba, T.1    Mayer-Proschel, M.2    Rao, M.S.3
  • 37
    • 0032053965 scopus 로고    scopus 로고
    • Aquaporin-4 water channel protein in the rat retina and optic nerve: Polarized expression in Müller cells and fibrous astrocytes
    • E.A. Nagelhus, M.L. Veruki, R. Torp, F.M. Haug, J.H. Laake, S. Nielsen, P. Agre, and O.P. Ottersen Aquaporin-4 water channel protein in the rat retina and optic nerve: Polarized expression in Müller cells and fibrous astrocytes J. Neurosci. 18 1998 2506 2519
    • (1998) J. Neurosci. , vol.18 , pp. 2506-2519
    • Nagelhus, E.A.1    Veruki, M.L.2    Torp, R.3    Haug, F.M.4    Laake, J.H.5    Nielsen, S.6    Agre, P.7    Ottersen, O.P.8
  • 38
    • 43249098296 scopus 로고    scopus 로고
    • Axon-glial signaling and the glial support of axon function
    • K.A. Nave, and B.D. Trapp Axon-glial signaling and the glial support of axon function Annu. Rev. Neurosci. 31 2008 535 561
    • (2008) Annu. Rev. Neurosci. , vol.31 , pp. 535-561
    • Nave, K.A.1    Trapp, B.D.2
  • 39
    • 0030063699 scopus 로고    scopus 로고
    • Co-localization of NG2 proteoglycan and PDGF α-receptor on O2A progenitor cells in the developing rat brain
    • DOI 10.1002/(SICI)1097-4547(19960201)43:3<299::AID-JNR5>3.0.CO;2-E
    • A. Nishiyama, X.H. Lin, N. Giese, C.H. Heldin, and W.B. Stallcup Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain J. Neurosci. Res. 43 1996 299 314 (Pubitemid 26054018)
    • (1996) Journal of Neuroscience Research , vol.43 , Issue.3 , pp. 299-314
    • Nishiyama, A.1    Lin, X.-H.2    Giese, N.3    Heldin, C.-H.4    Stallcup, W.B.5
  • 40
    • 0037395114 scopus 로고    scopus 로고
    • Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain
    • M.C. Nunes, N.S. Roy, H.M. Keyoung, R.R. Goodman, G. McKhann 2nd, L. Jiang, J. Kang, M. Nedergaard, and S.A. Goldman Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain Nat. Med. 9 2003 439 447
    • (2003) Nat. Med. , vol.9 , pp. 439-447
    • Nunes, M.C.1    Roy, N.S.2    Keyoung, H.M.3    Goodman, R.R.4    McKhann II, G.5    Jiang, L.6    Kang, J.7    Nedergaard, M.8    Goldman, S.A.9
  • 42
    • 0026689059 scopus 로고
    • PDGF receptors in the rat CNS: During late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage
    • N.P. Pringle, H.S. Mudhar, E.J. Collarini, and W.D. Richardson PDGF receptors in the rat CNS: during late neurogenesis, PDGF alpha-receptor expression appears to be restricted to glial cells of the oligodendrocyte lineage Development 115 1992 535 551
    • (1992) Development , vol.115 , pp. 535-551
    • Pringle, N.P.1    Mudhar, H.S.2    Collarini, E.J.3    Richardson, W.D.4
  • 43
    • 0020538298 scopus 로고
    • A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium
    • M.C. Raff, R.H. Miller, and M. Noble A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium Nature 303 1983 390 396
    • (1983) Nature , vol.303 , pp. 390-396
    • Raff, M.C.1    Miller, R.H.2    Noble, M.3
  • 44
    • 0023620013 scopus 로고
    • Expression of growth factor receptors in injured nervous tissue. II. Induction of specific platelet-derived growth factor binding in the injured PNS is associated with a breakdown in the blood-nerve barrier and endoneurial interstitial oedema
    • G. Raivich, and G.W. Kreutzberg Expression of growth factor receptors in injured nervous tissue. II. Induction of specific platelet-derived growth factor binding in the injured PNS is associated with a breakdown in the blood-nerve barrier and endoneurial interstitial oedema J. Neurocytol. 16 1987 701 711
    • (1987) J. Neurocytol. , vol.16 , pp. 701-711
    • Raivich, G.1    Kreutzberg, G.W.2
  • 46
    • 0033215282 scopus 로고    scopus 로고
    • Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination
    • S.A. Shields, J.M. Gilson, W.F. Blakemore, and R.J.M. Franklin Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination Glia 28 1999 77 83
    • (1999) Glia , vol.28 , pp. 77-83
    • Shields, S.A.1    Gilson, J.M.2    Blakemore, W.F.3    Franklin, R.J.M.4
  • 47
    • 0036382851 scopus 로고    scopus 로고
    • Expression of the POU-domain transcription factors SCIP/Oct-6 and Brn-2 is associated with Schwann cell but not oligodendrocyte remyelination of the CNS
    • F.J. Sim, C. Zhao, W.W. Li, A. Lakatos, and R.J.M. Franklin Expression of the POU-domain transcription factors SCIP/Oct-6 and Brn-2 is associated with Schwann cell but not oligodendrocyte remyelination of the CNS Mol. Cell. Neurosci. 20 2002 669 682
    • (2002) Mol. Cell. Neurosci. , vol.20 , pp. 669-682
    • Sim, F.J.1    Zhao, C.2    Li, W.W.3    Lakatos, A.4    Franklin, R.J.M.5
  • 48
    • 0036549138 scopus 로고    scopus 로고
    • The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation
    • F.J. Sim, C. Zhao, J. Penderis, and R.J.M. Franklin The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation J. Neurosci. 22 2002 2451 2459
    • (2002) J. Neurosci. , vol.22 , pp. 2451-2459
    • Sim, F.J.1    Zhao, C.2    Penderis, J.3    Franklin, R.J.M.4
  • 49
    • 0018774226 scopus 로고
    • Central remyelination restores secure conduction
    • E.J. Smith, W.F. Blakemore, and W.I. McDonald Central remyelination restores secure conduction Nature 280 1979 395 396
    • (1979) Nature , vol.280 , pp. 395-396
    • Smith, E.J.1    Blakemore, W.F.2    McDonald, W.I.3
  • 50
    • 0016598060 scopus 로고
    • Progressive demyelination and reparative phenomena in chronic experimental allergic encephalomyelitis
    • D.H. Snyder, M.P. Valsamis, S.H. Stone, and C.S. Raine Progressive demyelination and reparative phenomena in chronic experimental allergic encephalomyelitis J. Neuropathol. Exp. Neurol. 34 1975 209 221
    • (1975) J. Neuropathol. Exp. Neurol. , vol.34 , pp. 209-221
    • Snyder, D.H.1    Valsamis, M.P.2    Stone, S.H.3    Raine, C.S.4
  • 51
    • 0038643444 scopus 로고    scopus 로고
    • Astrocytes as stem cells: Nomenclature, phenotype, and translation
    • D.A. Steindler, and E.D. Laywell Astrocytes as stem cells: Nomenclature, phenotype, and translation Glia 43 2003 62 69
    • (2003) Glia , vol.43 , pp. 62-69
    • Steindler, D.A.1    Laywell, E.D.2
  • 52
    • 13444305196 scopus 로고    scopus 로고
    • Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes
    • J.F. Talbott, D.N. Loy, Y. Liu, M.S. Qiu, M.B. Bunge, M.S. Rao, and S.R. Whittemore Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes Exp. Neurol. 192 2005 11 24
    • (2005) Exp. Neurol. , vol.192 , pp. 11-24
    • Talbott, J.F.1    Loy, D.N.2    Liu, Y.3    Qiu, M.S.4    Bunge, M.B.5    Rao, M.S.6    Whittemore, S.R.7
  • 53
    • 33747186391 scopus 로고    scopus 로고
    • Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent
    • J.F. Talbott, Q. Cao, G.U. Enzmann, R.L. Benton, V. Achim, X.X. Cheng, M.D. Mills, M.S. Rao, and S.R. Whittemore Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent Glia 54 2006 147 159
    • (2006) Glia , vol.54 , pp. 147-159
    • Talbott, J.F.1    Cao, Q.2    Enzmann, G.U.3    Benton, R.L.4    Achim, V.5    Cheng, X.X.6    Mills, M.D.7    Rao, M.S.8    Whittemore, S.R.9
  • 54
    • 48249139449 scopus 로고    scopus 로고
    • Multiple sclerosis: An immune or neurodegenerative disorder?
    • B.D. Trapp, and K.A. Nave Multiple sclerosis: An immune or neurodegenerative disorder? Annu. Rev. Neurosci. 31 2008 247 269
    • (2008) Annu. Rev. Neurosci. , vol.31 , pp. 247-269
    • Trapp, B.D.1    Nave, K.A.2
  • 55
    • 0037106212 scopus 로고    scopus 로고
    • Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion
    • M. Watanabe, Y. Toyama, and A. Nishiyama Differentiation of proliferated NG2-positive glial progenitor cells in a remyelinating lesion J. Neurosci. Res. 69 2002 826 836
    • (2002) J. Neurosci. Res. , vol.69 , pp. 826-836
    • Watanabe, M.1    Toyama, Y.2    Nishiyama, A.3
  • 56
    • 0033082118 scopus 로고    scopus 로고
    • Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: A comparative study
    • R.H. Woodruff, and R.J.M. Franklin Demyelination and remyelination of the caudal cerebellar peduncle of adult rats following stereotaxic injections of lysolecithin, ethidium bromide, and complement/anti-galactocerebroside: A comparative study Glia 25 1999 216 228
    • (1999) Glia , vol.25 , pp. 216-228
    • Woodruff, R.H.1    Franklin, R.J.M.2
  • 57
    • 77952571743 scopus 로고    scopus 로고
    • An Fgfr3-iCreER(T2) transgenic mouse line for studies of neural stem cells and astrocytes
    • K.M. Young, T. Mitsumori, N. Pringle, M. Grist, N. Kessaris, and W.D. Richardson An Fgfr3-iCreER(T2) transgenic mouse line for studies of neural stem cells and astrocytes Glia 2010 in press. Published online February 12, 2010
    • (2010) Glia
    • Young, K.M.1    Mitsumori, T.2    Pringle, N.3    Grist, M.4    Kessaris, N.5    Richardson, W.D.6
  • 58
    • 0033616730 scopus 로고    scopus 로고
    • Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity
    • S.C. Zhang, B. Ge, and I.D. Duncan Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity Proc. Natl. Acad. Sci. USA 96 1999 4089 4094
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4089-4094
    • Zhang, S.C.1    Ge, B.2    Duncan, I.D.3
  • 59
    • 38849095193 scopus 로고    scopus 로고
    • NG2 cells generate both oligodendrocytes and gray matter astrocytes
    • X. Zhu, D.E. Bergles, and A. Nishiyama NG2 cells generate both oligodendrocytes and gray matter astrocytes Development 135 2008 145 157
    • (2008) Development , vol.135 , pp. 145-157
    • Zhu, X.1    Bergles, D.E.2    Nishiyama, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.