A crucial role for p57Kip2 in the intracellular timer that controls oligodendrocyte differentiation

Journal of Neuroscience

Volumn 27, Issue 23, 2007, Pages 6185-6196

  Dugas, Jason C ^a   Ibrahim, Adiljan ^a   Barres, Ben A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CDKN1C; Id4; Multiple sclerosis; Myelin; Oligodendrocyte; p57Kip2; ZFP536

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CLONE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TYPE; DAUGHTER CELL; IN VITRO STUDY; MOLECULAR MECHANICS; MOLECULE; MOUSE; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; STEM CELL;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL CLOCKS; CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P57; INTRACELLULAR FLUID; MICE; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 34250012532     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0628-07.2007     Document Type: Article

References (48)

1. Baas D, Bourbeau D, Sarlieve LL, Ittel ME, Dussault JH, Puymirat J (1997) Oligodendrocyte maturation and progenitor cell proliferation are independently regulated by thyroid hormone. Glia 19:324-332.
2. Balint E, Phillips AC, Kozlov S, Stewart CL, Vousden KH (2002) Induction of p57(KIP2) expression by p73beta. Proc Natl Acad Sci USA 99:3529-3534.
3. Barres BA, Raff MC (1994) Control of oligodendrocyte number in the developing rat optic nerve. Neuron 12:935-942.
4. Barres BA, Hart IK, Coles HS, Burne JF, Voyvodic JT, Richardson WD, Raff MC (1992) Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70:31-46.
5. Barres BA, Schmid R, Sendnter M, Raff MC (1993) Multiple extracellular signals are required for long-term oligodendrocyte survival. Development 118:283-295.
6. Barres BA, Lazar MA, Raff MC (1994a) A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development 120:1097-1108.
7. Barres BA, Raff MC, Gaese F, Bartke I, Dechant G, Barde YA (1994b) A crucial role for neurotrophin-3 in oligodendrocyte development. Nature 367:371-375.
8. Baumann N, Pham-Dinh D (2001) Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev 81:871-927.
9. Billon N, Terrinoni A, Jolicoeur C, McCarthy A, Richardson WD, Melino G, Raff M (2004) Roles for p53 and p73 during oligodendrocyte development. Development 131:1211-1220.
10. Casaccia-Bonnefil P, Liu A (2003) Relationship between cell cycle molecules and onset of oligodendrocyte differentiation. J Neurosci Res 72:1-11.
11. Casaccia-Bonnefil P, Hardy RJ, Teng KK, Levine JM, Koff A, Chao MV (1999) Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation. Development 126:4027-4037.
12. Cunningham JJ, Roussel MF (2001) Cyclin-dependent kinase inhibitors in the development of the central nervous system. Cell Growth Differ 12:387-396.
13. Dugas JC, Tai Y-C, Speed TP, Ngai J, Barres BA (2006) Functional genomic analysis of oligodendrocyte differentiation. J Neurosci 26:10967-10983.
14. Durand B, Gao FB, Raff M (1997) Accumulation of the cyclin-dependent kinase inhibitor p27/Kip1 and the timing of oligodendrocyte differentiation. EMBO J 16:306-317.
15. Dussault JH, Ruel J (1987) Thyroid hormones and brain development. Annu Rev Physiol 49:321-334.
16. Figliola R, Maione R (2004) MyoD induces the expression of p57Kip2 in cells lacking p21Cip1/Waf1: overlapping and distinct functions of the two cdk inhibitors. J Cell Physiol 200:468-475.
17. Gao FB, Durand B, Raff M (1997) Oligodendrocyte precursor cells count time but not cell divisions before differentiation. Curr Biol 7:152-155.
18. Georgia S, Soliz R, Li M, Zhang P, Bhushan A (2006) p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol 298:22-31.
19. Ghiani C, Gallo V (2001) Inhibition of cyclin E-cyclin-dependent kinase 2 complex formation and activity is associated with cell cycle arrest and withdrawal in oligodendrocyte progenitor cells. J Neurosci 21:1274-1282.
20. Hardy RJ (1997) Dorsoventral patterning and oligodendroglial specification in the developing central nervous system. J Neurosci Res 50:139-145.
21. Itoh Y, Masuyama N, Nakayama K, Nakayama KI, Gotoh Y (2007) The cyclin-dependent kinase inhibitors p57 and p27 regulate neuronal migration in the developing mouse neocortex. J Biol Chem 282:390-396.
22. Joseph B, Wallen-Mackenzie A, Benoit G, Murata T, Joodmardi E, Okret S, Perlmann T (2003) p57(Kip2) cooperates with Nurr1 in developing dopamine cells. Proc Natl Acad Sci USA 100:15619-15624.
23. Kondo T, Raff M (2000a) The Id4 HLH protein and the timing of oligodendrocyte differentiation. EMBO J 19:1998-2007.
24. Kondo T, Raff M (2000b) Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation. Development 127:2989-2998.
25. MacLean HE, Guo J, Knight MC, Zhang P, Cobrinik D, Kronenberg HM (2004) The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes. J Clin Invest 113:1334-1343.
26. Miskimins R, Srinivasan R, Marin-Husstege M, Miskimins WK, Casaccia-Bonnefil P (2002) p27(Kip1) enhances myelin basic protein gene promoter activity. J Neurosci Res 67:100-105.
27. Myers TK, Andreuzza SE, Franklin DS (2004) p18INK4c and p27KIP1 are required for cell cycle arrest of differentiated myotubes. Exp Cell Res 300:365-378.
28. Park HC, Boyce J, Shin J, Appel B (2005) Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function. J Neurosci 25:6836-6844.
29. Raff MC, Miller RH, Noble M (1983) A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303:390-396.
30. Reynaud EG, Guillier M, Leibovitch MP, Leibovitch SA (2000) Dimerization of the amino terminal domain of p57Kip2 inhibits cyclin D1-cdk4 kinase activity. Oncogene 19:1147-1152.
31. Riechmann V, van Cruchten I, Sablitzky F (1994) The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res 22:749-755.
32. Rothschild G, Zhao X, Iavarone A, Lasorella A (2006) E Proteins and Id2 converge on p57Kip2 to regulate cell cycle in neural cells. Mol Cell Biol 26:4351-4361.
33. Scandura JM, Boccuni P, Massague J, Nimer SD (2004) Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proc Natl Acad Sci USA 101:15231-15236.
34. Shi J, Marinovich A, Barres BA (1998) Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve. J Neurosci 18:4627-4636.
35. Sun XH, Copeland NG, Jenkins NA, Baltimore D (1991) Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol Cell Biol 11:5603-5611.
36. Takahashi K, Nakayama K, Nakayama K (2000) Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation. J Biochem (Tokyo) 127:73-83.
37. Tang DG, Tokumoto YM, Raff MC (2000) Long-term culture of purified postnatal oligodendrocyte precursor cells. Evidence for an intrinsic maturation program that plays out over months. J Cell Biol 148:971-984.
38. Tang XM, Beesley JS, Grinspan JB, Seth P, Kamholz J, Cambi F (1999) Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation. J Cell Biochem 76:270-279.
39. Temple S, Raff MC (1986) Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell 44:773-779.
40. Tokumoto YM, Tang DG, Raff MC (2001) Two molecularly distinct intracellular pathways to oligodendrocyte differentiation: role of a p53 family protein. EMBO J 20:5261-5268.
41. Tokumoto YM, Apperly JA, Gao FB, Raff MC (2002) Posttranscriptional regulation of p18 and p27 Cdk inhibitor proteins and the timing of oligodendrocyte differentiation. Dev Biol 245:224-234.
42. Vaccarello G, Figliola R, Cramerotti S, Novelli F, Maione R (2006) p57Kip2 is induced by MyoD through a p73-dependent pathway. J Mol Biol 356:578-588.
43. Walters SN, Morell P (1981) Effects of altered thyroid states on myelinogenesis. J Neurochem 36:1792-1801.
44. Wei Q, Miskimins WK, Miskimins R (2003) The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression. Mol Cell Biol 23:4035-4045.
45. Wei Q, Miskimins WK, Miskimins R (2004) Sox10 acts as a tissue-specific transcription factor enhancing activation of the myelin basic protein gene promoter by p27Kip1 and Sp1. J Neurosci Res 78:796-802.
46. Zezula J, Casaccia-Bonnefil P, Ezhevsky SA, Osterhout DJ, Levine JM, Dowdy SF, Chao MV, Koff A (2001) p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal. EMBO Rep 2:27-34.
47. Zhang P, Wong C, DePinho RA, Harper JW, Elledge SJ (1998) Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development. Genes Dev 12:3162-3167.
48. Zhang P, Wong C, Liu D, Finegold M, Harper JW, Elledge SJ (1999) p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step. Genes Dev 13:213-224.