Expression of dominant-negative and chimeric subunits reveals an essential role for β1 integrin during myelination

Current Biology

Volumn 11, Issue 13, 2001, Pages 1039-1043

  Relvas, João B ^a   Setzu, Anna ^a   Baron, Wia ^a   Buttery, Philip C ^a,c   LaFlamme, Susan E ^d   Franklin, Robin J M ^b   Ffrench Constant, Charles ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035838420     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00292-5     Document Type: Article

References (18)

1. The oligodendrocyte and its many cellular processes
2. Rho GTPases and the actin cytoskeleton
3. A developmental analysis of oligodendroglial integrins in primary cells: Changes in αv-associated β subunits during differentiation
4. Expression of αvβ3 and αvβ8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons
5. Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes
6. Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly
7. Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality
8. Consequences of lack of beta 1 integrin gene expression in mice
9. Development of mammary gland requires normal beta 1-integrin function
10. Impaired bone formation in transgenic mice resulting from altered integrin function in osteoblasts
11. Transplanting oligodendrocyte progenitors into the adult CNS
12. Integrin α subunit ratios, cytoplasmic domains, and growth factor synergy regulate muscle proliferation and differentiation
13. PS cytoplasmic domain is sufficient to regulate gene expression in the Drosophila embryo
14. Integrins as mediators of morphogenesis in Drosophila
15. Laminin-like proteins are differentially regulated during cerebellar development and stimulate granule cell neurite outgrowth in vitro
16. Regulation of mitogen-activated protein kinase activation by the cytoplasmic domain of the alpha6 integrin subunit
17. Integrin cytoplasmic domain-binding proteins
18. Activated R-ras, Rac1, PI 3-kinase and PKCepsilon can each restore cell spreading inhibited by isolated integrin beta1 cytoplasmic domains