Mining electron density for functionally relevant protein polysterism in crystal structures

Cellular and Molecular Life Sciences

Volumn 68, Issue 11, 2011, Pages 1829-1841

  Fraser, James S ^a   Jackson, Colin J ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Catalysis; Conformational substates; Evolution; NMR; Polysterism; Protein dynamics; X ray crystallography

Indexed keywords

ACETYLCHOLINESTERASE; ADENYLATE KINASE; CYCLOPHILIN A; GLUCOCORTICOID RECEPTOR; PHOSPHOTRIESTERASE; PROTEIN C;

BINDING AFFINITY; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DATA MINING; HYDROGEN BOND; HYDROPHOBICITY; ISOMERIZATION; LIGAND BINDING; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; PROTEIN POLYSTERISM; PROTEIN STRUCTURE; PROTEIN UNFOLDING; RADIATION SCATTERING; REVIEW; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ANIMALS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; EVOLUTION, MOLECULAR; HUMANS; MOLECULAR CONFORMATION; PROTEINS;

EID: 79958207530     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0611-4     Document Type: Review

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