Conformational changes affect binding and catalysis by ester-hydrolysing antibodies

Journal of Molecular Biology

Volumn 285, Issue 1, 1999, Pages 421-430

  Lindner, Ariel B ^a   Eshhar, Zelig ^a   Tawfik, Dan S ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Catalytic antibodies; Hysteresis; Induced fit; Polyethylene glycol; Pre equilibrium

Indexed keywords

CATALYTIC ANTIBODY; ESTER;

ANIMAL EXPERIMENT; ANTIGEN BINDING; ARTICLE; BINDING KINETICS; CATALYSIS; CONFORMATIONAL TRANSITION; HYDROLYSIS; HYSTERESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0033534360     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2309     Document Type: Article

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