Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 7, 2003, Pages 3895-3900

  Johnson, Sean J ^a   Taylor, Jeffrey S ^a   Beese, Lorena S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; NUCLEOTIDE; PRIMER DNA;

ARTICLE; BACILLUS; CATALYSIS; CHROMOSOME TRANSLOCATION; CONFORMATION; CRYSTAL; CRYSTAL STRUCTURE; DNA ADDUCT; DNA REPLICATION; DNA SYNTHESIS; FRAMESHIFT MUTATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; REACTION ANALYSIS; BINDING SITE; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; DNA TEMPLATE; GENE TRANSLOCATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE;

INSERTION SEQUENCES;

BACILLUS; BASE SEQUENCE; BINDING SITES; CRYSTALLIZATION; DNA POLYMERASE I; DNA PRIMERS; DNA REPLICATION; FRAMESHIFT MUTATION; MODELS, GENETIC; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; TEMPLATES, GENETIC; TRANSLOCATION, GENETIC;

EID: 0037388383     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0630532100     Document Type: Article

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