Automated electron-density sampling reveals widespread conformational polymorphism in proteins

Protein Science

Volumn 19, Issue 7, 2010, Pages 1420-1431

  Lang, P Therese ^a   Ng, Ho Leung ^a,d   Fraser, James S ^a   Corn, Jacob E ^a,e   Echols, Nathaniel ^a,c   Sales, Mark ^a,f   Holton, James M ^b,c   Alber, Tom ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d Advanced Light Source Lawrence Berkeley National Laboratory ^*  (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^f Stormweaver Programming   (United States)

Author keywords

Electron density sampling; Rotamers; Side chain ensembles; Structural polymorphism; X ray crystallography

Indexed keywords

CALMODULIN; PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN POLYMORPHISM; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY;

CALMODULIN; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEINS;

EID: 77953977241     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.423     Document Type: Article

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