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Volumn 1816, Issue 2, 2011, Pages 105-118

The neuronal influence on tumor progression

Author keywords

Axon guidance molecules; Cancer progression; Neoneurogenesis; Neuropeptides; Neurotransmitters; Neurotrophic factors; Perineural invasion

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ADRENALIN; BRAIN DERIVED NEUROTROPHIC FACTOR; DOPAMINE; EPHRIN; FIBROBLAST GROWTH FACTOR; GLUTAMIC ACID; MUSCARINIC RECEPTOR BLOCKING AGENT; NERVE GROWTH FACTOR; NETRIN; NETRIN RECEPTOR; NEUROPEPTIDE; NEUROTROPHIC FACTOR; NEUROTROPHIN 1; NEUROTROPHIN 3; NICOTINIC RECEPTOR BLOCKING AGENT; NORADRENALIN; PROTEIN TYROSINE KINASE INHIBITOR; RECEPTOR; SEMAPHORIN; SEROTONIN; TACHYKININ; TRANSFORMING GROWTH FACTOR; UNCLASSIFIED DRUG;

EID: 79957967279     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2011.04.005     Document Type: Review
Times cited : (127)

References (241)
  • 1
    • 75549083303 scopus 로고    scopus 로고
    • Tumor heterogeneity: causes and consequences
    • A. Marusyk, K. Polyak, Tumor heterogeneity: causes and consequences, Biochim. Biophys. Acta 1805 (2010) 105-117.
    • (2010) Biochim. Biophys. Acta , vol.1805 , pp. 105-117
    • Marusyk, A.1    Polyak, K.2
  • 2
    • 0015008620 scopus 로고
    • Isolation of a tumor factor responsible for angiogenesis
    • J. Folkman, E. Merler, C. Abernathy, G. Williams, Isolation of a tumor factor responsible for angiogenesis, J. Exp. Med. 133 (1971) 275-288.
    • (1971) J. Exp. Med. , vol.133 , pp. 275-288
    • Folkman, J.1    Merler, E.2    Abernathy, C.3    Williams, G.4
  • 4
    • 56749174211 scopus 로고    scopus 로고
    • FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy?
    • C. Fischer, M. Mazzone, B. Jonckx, P. Carmeliet, FLT1 and its ligands VEGFB and PlGF: drug targets for anti-angiogenic therapy? Nat. Rev. Cancer 8 (2008) 942-956.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 942-956
    • Fischer, C.1    Mazzone, M.2    Jonckx, B.3    Carmeliet, P.4
  • 5
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: mechanisms of anti-tumour activity
    • L.M. Ellis, D.J. Hicklin, VEGF-targeted therapy: mechanisms of anti-tumour activity, Nat. Rev. Cancer 8 (2008) 579-591.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 7
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • G. Bergers, D. Hanahan, Modes of resistance to anti-angiogenic therapy, Nat. Rev. Cancer 8 (2008) 592-603.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 8
    • 30744477450 scopus 로고    scopus 로고
    • Lymphangiogenesis in development and human disease
    • K. Alitalo, T. Tammela, T.V. Petrova, Lymphangiogenesis in development and human disease, Nature 438 (2005) 946-953.
    • (2005) Nature , vol.438 , pp. 946-953
    • Alitalo, K.1    Tammela, T.2    Petrova, T.V.3
  • 9
    • 21144437844 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels
    • Y. He, I. Rajantie, K. Pajusola, M. Jeltsch, T. Holopainen, S. Yla-Herttuala, T. Harding, K. Jooss, T. Takahashi, K. Alitalo, Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels, Cancer Res. 65 (2005) 4739-4746.
    • (2005) Cancer Res , vol.65 , pp. 4739-4746
    • He, Y.1    Rajantie, I.2    Pajusola, K.3    Jeltsch, M.4    Holopainen, T.5    Yla-Herttuala, S.6    Harding, T.7    Jooss, K.8    Takahashi, T.9    Alitalo, K.10
  • 10
    • 33746012247 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis and metastatic spread-new players begin to emerge
    • M.G. Achen, S.A. Stacker, Tumor lymphangiogenesis and metastatic spread-new players begin to emerge, Int. J. Cancer 119 (2006) 1755-1760.
    • (2006) Int. J. Cancer , vol.119 , pp. 1755-1760
    • Achen, M.G.1    Stacker, S.A.2
  • 11
    • 0036310316 scopus 로고    scopus 로고
    • The role of tumor lymphangiogenesis in metastatic spread
    • S.A. Stacker, M.E. Baldwin, M.G. Achen, The role of tumor lymphangiogenesis in metastatic spread, FASEB J. 16 (2002) 922-934.
    • (2002) FASEB J. , vol.16 , pp. 922-934
    • Stacker, S.A.1    Baldwin, M.E.2    Achen, M.G.3
  • 12
    • 17844400919 scopus 로고    scopus 로고
    • Is lymphangiogenesis as important as angiogenesis?
    • C. Orellana, Is lymphangiogenesis as important as angiogenesis? Lancet Oncol. 6 (2005) 265.
    • (2005) Lancet Oncol. , vol.6 , pp. 265
    • Orellana, C.1
  • 13
    • 0036120711 scopus 로고    scopus 로고
    • Nerve fibers in tumors of the human urinary bladder
    • P. Seifert, M. Benedic, P. Effert, Nerve fibers in tumors of the human urinary bladder, Virchows Arch. 440 (2002) 291-297.
    • (2002) Virchows Arch. , vol.440 , pp. 291-297
    • Seifert, P.1    Benedic, M.2    Effert, P.3
  • 14
    • 0035079216 scopus 로고    scopus 로고
    • Tumours may be innervated
    • P. Seifert, M. Spitznas, Tumours may be innervated, Virchows Arch. 438 (2001) 228-231.
    • (2001) Virchows Arch , vol.438 , pp. 228-231
    • Seifert, P.1    Spitznas, M.2
  • 15
    • 0036243090 scopus 로고    scopus 로고
    • Axons in human choroidal melanoma suggest the participation of nerves in the control of these tumors
    • P. Seifert, M. Spitznas, Axons in human choroidal melanoma suggest the participation of nerves in the control of these tumors, Am. J. Ophthalmol. 133 (2002) 711-713.
    • (2002) Am. J. Ophthalmol. , vol.133 , pp. 711-713
    • Seifert, P.1    Spitznas, M.2
  • 16
    • 0036016203 scopus 로고    scopus 로고
    • Cholinergic innervation and function in the prostate gland
    • S. Ventura, J. Pennefather, F. Mitchelson, Cholinergic innervation and function in the prostate gland, Pharmacol. Ther. 94 (2002) 93-112.
    • (2002) Pharmacol. Ther. , vol.94 , pp. 93-112
    • Ventura, S.1    Pennefather, J.2    Mitchelson, F.3
  • 17
    • 0028060232 scopus 로고
    • Are breast tumours innervated? Immunohistological investigations using antibodies against the neuronal marker protein gene product 9.5 (PGP 9.5) in benign and malignant breast lesions
    • B.S. Mitchell, U. Schumacher, V.V. Stauber, E. Kaiserling, Are breast tumours innervated? Immunohistological investigations using antibodies against the neuronal marker protein gene product 9.5 (PGP 9.5) in benign and malignant breast lesions, Eur. J. Cancer 30A (1994) 1100-1103.
    • (1994) Eur. J. Cancer , vol.30 A , pp. 1100-1103
    • Mitchell, B.S.1    Schumacher, U.2    Stauber, V.V.3    Kaiserling, E.4
  • 18
    • 0026600727 scopus 로고
    • Neural invasion in intraductal carcinoma of the breast
    • W.Y. Tsang, J.K. Chan, Neural invasion in intraductal carcinoma of the breast, Hum. Pathol. 23 (1992) 202-204.
    • (1992) Hum. Pathol. , vol.23 , pp. 202-204
    • Tsang, W.Y.1    Chan, J.K.2
  • 19
    • 34748883778 scopus 로고    scopus 로고
    • The nature of neural invasion by pancreatic cancer
    • M. Kayahara, H. Nakagawara, H. Kitagawa, T. Ohta, The nature of neural invasion by pancreatic cancer, Pancreas 35 (2007) 218-223.
    • (2007) Pancreas , vol.35 , pp. 218-223
    • Kayahara, M.1    Nakagawara, H.2    Kitagawa, H.3    Ohta, T.4
  • 20
    • 0028000265 scopus 로고
    • Are tumours innervated? Immunohistological investigations using antibodies against the neuronal marker protein gene product 9.5 (PGP 9.5) in benign, malignant and experimental tumours
    • B.S. Mitchell, U. Schumacher, E. Kaiserling, Are tumours innervated? Immunohistological investigations using antibodies against the neuronal marker protein gene product 9.5 (PGP 9.5) in benign, malignant and experimental tumours, Tumour Biol. 15 (1994) 269-274.
    • (1994) Tumour Biol. , vol.15 , pp. 269-274
    • Mitchell, B.S.1    Schumacher, U.2    Kaiserling, E.3
  • 21
    • 0037345096 scopus 로고    scopus 로고
    • Peptidergic innervation of human esophageal and cardiac carcinoma
    • S.H. Lu, Y. Zhou, H.P. Que, S.J. Liu, Peptidergic innervation of human esophageal and cardiac carcinoma, World J. Gastroenterol. 9 (2003) 399-403.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 399-403
    • Lu, S.H.1    Zhou, Y.2    Que, H.P.3    Liu, S.J.4
  • 22
    • 0035157891 scopus 로고    scopus 로고
    • In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer
    • G.E. Ayala, T.M. Wheeler, H.D. Shine, M. Schmelz, A. Frolov, S. Chakraborty, D. Rowley, In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer, Prostate 49 (2001) 213-223.
    • (2001) Prostate , vol.49 , pp. 213-223
    • Ayala, G.E.1    Wheeler, T.M.2    Shine, H.D.3    Schmelz, M.4    Frolov, A.5    Chakraborty, S.6    Rowley, D.7
  • 23
    • 33751214236 scopus 로고    scopus 로고
    • Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer
    • J.P. Godbout, R. Glaser, Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer, J. Neuroimmune Pharmacol. 1 (2006) 421-427.
    • (2006) J. Neuroimmune Pharmacol. , vol.1 , pp. 421-427
    • Godbout, J.P.1    Glaser, R.2
  • 26
    • 4544321026 scopus 로고    scopus 로고
    • Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs
    • K. Lang, T.L.t. Drell, A. Lindecke, B. Niggemann, C. Kaltschmidt, K.S. Zaenker, F. Entschladen, Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs, Int. J. Cancer 112 (2004) 231-238.
    • (2004) Int. J. Cancer , vol.112 , pp. 231-238
    • Lang, K.1    Drell, T.L.T.2    Lindecke, A.3    Niggemann, B.4    Kaltschmidt, C.5    Zaenker, K.S.6    Entschladen, F.7
  • 27
    • 1642325724 scopus 로고    scopus 로고
    • Tumour-cell migration, invasion, and metastasis: navigation by neurotransmitters
    • F. Entschladen, T.L.t. Drell, K. Lang, J. Joseph, K.S. Zaenker, Tumour-cell migration, invasion, and metastasis: navigation by neurotransmitters, Lancet Oncol. 5 (2004) 254-258.
    • (2004) Lancet Oncol , vol.5 , pp. 254-258
    • Entschladen, F.1    Drell, T.L.T.2    Lang, K.3    Joseph, J.4    Zaenker, K.S.5
  • 32
    • 23044512910 scopus 로고    scopus 로고
    • The brain within the tumor: new roles for axon guidance molecules in cancers
    • A. Chedotal, G. Kerjan, C. Moreau-Fauvarque, The brain within the tumor: new roles for axon guidance molecules in cancers, Cell Death Differ. 12 (2005) 1044-1056.
    • (2005) Cell Death Differ. , vol.12 , pp. 1044-1056
    • Chedotal, A.1    Kerjan, G.2    Moreau-Fauvarque, C.3
  • 33
  • 34
    • 68149170070 scopus 로고    scopus 로고
    • Perineural invasion in cancer: a review of the literature
    • C. Liebig, G. Ayala, J.A. Wilks, D.H. Berger, D. Albo, Perineural invasion in cancer: a review of the literature, Cancer 115 (2009) 3379-3391.
    • (2009) Cancer , vol.115 , pp. 3379-3391
    • Liebig, C.1    Ayala, G.2    Wilks, J.A.3    Berger, D.H.4    Albo, D.5
  • 35
    • 0014136803 scopus 로고
    • Nature of the perineural space invaded by prostatic carcinoma
    • A.E. Rodin, D.L. Larson, D.K. Roberts, Nature of the perineural space invaded by prostatic carcinoma, Cancer 20 (1967) 1772-1779.
    • (1967) Cancer , vol.20 , pp. 1772-1779
    • Rodin, A.E.1    Larson, D.L.2    Roberts, D.K.3
  • 39
    • 10344239412 scopus 로고    scopus 로고
    • Netrin-1 and its receptors in tumorigenesis
    • H. Arakawa, Netrin-1 and its receptors in tumorigenesis, Nat. Rev. Cancer 4 (2004) 978-987.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 978-987
    • Arakawa, H.1
  • 40
    • 0025748761 scopus 로고
    • Molecular mechanisms of axon growth and guidance
    • J.L. Bixby, W.A. Harris, Molecular mechanisms of axon growth and guidance, Annu. Rev. Cell Biol. 7 (1991) 117-159.
    • (1991) Annu. Rev. Cell Biol. , vol.7 , pp. 117-159
    • Bixby, J.L.1    Harris, W.A.2
  • 41
    • 0036713578 scopus 로고    scopus 로고
    • Molecular control of neuronal migration
    • H.T. Park, J. Wu, Y. Rao, Molecular control of neuronal migration, Bioessays 24 (2002) 821-827.
    • (2002) Bioessays , vol.24 , pp. 821-827
    • Park, H.T.1    Wu, J.2    Rao, Y.3
  • 42
    • 0022871503 scopus 로고
    • Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrices
    • K.J. Tomaselli, L.F. Reichardt, J.L. Bixby, Distinct molecular interactions mediate neuronal process outgrowth on non-neuronal cell surfaces and extracellular matrices, J. Cell Biol. 103 (1986) 2659-2672.
    • (1986) J. Cell Biol. , vol.103 , pp. 2659-2672
    • Tomaselli, K.J.1    Reichardt, L.F.2    Bixby, J.L.3
  • 43
    • 0343654691 scopus 로고
    • Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+ -dependent and -independent cell adhesion molecules
    • J.L. Bixby, R.S. Pratt, J. Lilien, L.F. Reichardt, Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+ -dependent and -independent cell adhesion molecules, Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 2555-2559.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 2555-2559
    • Bixby, J.L.1    Pratt, R.S.2    Lilien, J.3    Reichardt, L.F.4
  • 44
    • 0031194110 scopus 로고    scopus 로고
    • Effects of extracellular matrix components on axonal outgrowth from peripheral nerves of adult animals in vitro
    • D.A. Tonge, J.P. Golding, M. Edbladh, M. Kroon, P.E. Ekstrom, A. Edstrom, Effects of extracellular matrix components on axonal outgrowth from peripheral nerves of adult animals in vitro, Exp. Neurol. 146 (1997) 81-90.
    • (1997) Exp. Neurol. , vol.146 , pp. 81-90
    • Tonge, D.A.1    Golding, J.P.2    Edbladh, M.3    Kroon, M.4    Ekstrom, P.E.5    Edstrom, A.6
  • 46
    • 77956082741 scopus 로고    scopus 로고
    • Initiating and growing an axon, Cold Spring Harb
    • F. Polleux, W. Snider, Initiating and growing an axon, Cold Spring Harb. Perspect. Biol. 2 (2010) a001925.
    • (2010) Perspect. Biol. , vol.2
    • Polleux, F.1    Snider, W.2
  • 47
    • 0025688095 scopus 로고
    • Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms
    • J.L. Bixby, P. Jhabvala, Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms, J. Cell Biol. 111 (1990) 2725-2732.
    • (1990) J. Cell Biol. , vol.111 , pp. 2725-2732
    • Bixby, J.L.1    Jhabvala, P.2
  • 48
  • 50
    • 33751184564 scopus 로고    scopus 로고
    • The dark side of the NGF family: neurotrophins in neoplasias
    • A. Kruttgen, I. Schneider, J. Weis, The dark side of the NGF family: neurotrophins in neoplasias, Brain Pathol. 16 (2006) 304-310.
    • (2006) Brain Pathol. , vol.16 , pp. 304-310
    • Kruttgen, A.1    Schneider, I.2    Weis, J.3
  • 52
    • 79151472084 scopus 로고    scopus 로고
    • Natural Antibodies Against Nerve Growth Factor Inhibit In Vitro Prostate Cancer Cell Metastasis
    • R.J. Warrington, K.E. Lewis, Natural Antibodies Against Nerve Growth Factor Inhibit In Vitro Prostate Cancer Cell Metastasis, Cancer Immunol. Immunother. 60 (2011) 187-195.
    • (2011) Cancer Immunol. Immunother. , vol.60 , pp. 187-195
    • Warrington, R.J.1    Lewis, K.E.2
  • 54
    • 78649756871 scopus 로고    scopus 로고
    • Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain
    • J.R. Ghilardi, K.T. Freeman, J.M. Jimenez-Andrade, W.G. Mantyh, A.P. Bloom, M.A. Kuskowski, P.W. Mantyh, Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain, Mol. Pain 6 (2010) 87.
    • (2010) Mol. Pain , vol.6 , pp. 87
    • Ghilardi, J.R.1    Freeman, K.T.2    Jimenez-Andrade, J.M.3    Mantyh, W.G.4    Bloom, A.P.5    Kuskowski, M.A.6    Mantyh, P.W.7
  • 55
    • 0025279814 scopus 로고
    • Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain
    • M. Hofer, S.R. Pagliusi, A. Hohn, J. Leibrock, Y.A. Barde, Regional distribution of brain-derived neurotrophic factor mRNA in the adult mouse brain, EMBO J. 9 (1990) 2459-2464.
    • (1990) EMBO J. , vol.9 , pp. 2459-2464
    • Hofer, M.1    Pagliusi, S.R.2    Hohn, A.3    Leibrock, J.4    Barde, Y.A.5
  • 56
    • 0025168085 scopus 로고
    • Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture
    • R.F. Alderson, A.L. Alterman, Y.A. Barde, R.M. Lindsay, Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture, Neuron 5 (1990) 297-306.
    • (1990) Neuron , vol.5 , pp. 297-306
    • Alderson, R.F.1    Alterman, A.L.2    Barde, Y.A.3    Lindsay, R.M.4
  • 58
    • 11244350959 scopus 로고    scopus 로고
    • Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma
    • Z.F. Yang, D.W. Ho, C.T. Lam, J.M. Luk, C.T. Lum, W.C. Yu, R.T. Poon, S.T. Fan, Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Res. 65 (2005) 219-225.
    • (2005) Cancer Res. , vol.65 , pp. 219-225
    • Yang, Z.F.1    Ho, D.W.2    Lam, C.T.3    Luk, J.M.4    Lum, C.T.5    Yu, W.C.6    Poon, R.T.7    Fan, S.T.8
  • 60
    • 78049491063 scopus 로고    scopus 로고
    • Overexpression of BDNF and TrkB in human bladder cancer specimens
    • P.C. Lai, T.H. Chiu, Y.T. Huang, Overexpression of BDNF and TrkB in human bladder cancer specimens, Oncol. Rep. 24 (2010) 1265-1270.
    • (2010) Oncol. Rep. , vol.24 , pp. 1265-1270
    • Lai, P.C.1    Chiu, T.H.2    Huang, Y.T.3
  • 61
    • 79952375922 scopus 로고    scopus 로고
    • The selective Trk inhibitor AZ623 inhibits brain-derived neurotrophic factor-mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan
    • P.E. Zage, T.C. Graham, L. Zeng, W. Fang, C. Pien, K. Thress, C. Omer, J.L. Brown, P.A. Zweidler-McKay, The selective Trk inhibitor AZ623 inhibits brain-derived neurotrophic factor-mediated neuroblastoma cell proliferation and signaling and is synergistic with topotecan, Cancer 117 (2011) 1321-1391.
    • (2011) Cancer , vol.117 , pp. 1321-1391
    • Zage, P.E.1    Graham, T.C.2    Zeng, L.3    Fang, W.4    Pien, C.5    Thress, K.6    Omer, C.7    Brown, J.L.8    Zweidler-McKay, P.A.9
  • 64
    • 0029084805 scopus 로고
    • Interleukin-6 family of cytokines and gp130
    • T. Kishimoto, S. Akira, M. Narazaki, T. Taga, Interleukin-6 family of cytokines and gp130, Blood 86 (1995) 1243-1254.
    • (1995) Blood , vol.86 , pp. 1243-1254
    • Kishimoto, T.1    Akira, S.2    Narazaki, M.3    Taga, T.4
  • 70
    • 0032792960 scopus 로고    scopus 로고
    • Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer
    • Z. Zhu, H. Friess, F.F. diMola, A. Zimmermann, H.U. Graber, M. Korc, M.W. Buchler, Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer, J. Clin. Oncol. 17 (1999) 2419-2428.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2419-2428
    • Zhu, Z.1    Friess, H.2    diMola, F.F.3    Zimmermann, A.4    Graber, H.U.5    Korc, M.6    Buchler, M.W.7
  • 73
    • 0032541677 scopus 로고    scopus 로고
    • Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis
    • A.C. Porter, R.R. Vaillancourt, Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis, Oncogene 17 (1998) 1343-1352.
    • (1998) Oncogene , vol.17 , pp. 1343-1352
    • Porter, A.C.1    Vaillancourt, R.R.2
  • 74
    • 0034530165 scopus 로고    scopus 로고
    • Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis
    • N. Dunker, K. Krieglstein, Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis, Eur. J. Biochem. 267 (2000) 6982-6988.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 6982-6988
    • Dunker, N.1    Krieglstein, K.2
  • 75
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: multifunctional regulators of vertebrate development
    • B.L. Hogan, Bone morphogenetic proteins: multifunctional regulators of vertebrate development, Genes Dev. 10 (1996) 1580-1594.
    • (1996) Genes Dev , vol.10 , pp. 1580-1594
    • Hogan, B.L.1
  • 76
    • 1842427952 scopus 로고    scopus 로고
    • Emerging roles for bone morphogenetic proteins in central nervous system glial biology
    • A.K. Hall, R.H. Miller, Emerging roles for bone morphogenetic proteins in central nervous system glial biology, J. Neurosci. Res. 76 (2004) 1-8.
    • (2004) J. Neurosci. Res. , vol.76 , pp. 1-8
    • Hall, A.K.1    Miller, R.H.2
  • 77
    • 77954557286 scopus 로고    scopus 로고
    • TGFbeta and cancer metastasis: an inflammation link
    • L. Yang, TGFbeta and cancer metastasis: an inflammation link, Cancer Metastasis Rev. 29 (2010) 263-271.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 263-271
    • Yang, L.1
  • 78
    • 0027251256 scopus 로고
    • A structural superfamily of growth factors containing a cystine knot motif
    • N.Q. McDonald, W.A. Hendrickson, A structural superfamily of growth factors containing a cystine knot motif, Cell 73 (1993) 421-424.
    • (1993) Cell , vol.73 , pp. 421-424
    • McDonald, N.Q.1    Hendrickson, W.A.2
  • 79
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family
    • K.A. Waite, C. Eng, From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family, Nat. Rev. Genet. 4 (2003) 763-773.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 80
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • P.M. Siegel, J. Massague, Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer, Nat. Rev. Cancer 3 (2003) 807-821.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 83
    • 30944444113 scopus 로고    scopus 로고
    • Alterations in components of the TGF-beta superfamily signaling pathways in human cancer
    • L. Levy, C.S. Hill, Alterations in components of the TGF-beta superfamily signaling pathways in human cancer, Cytokine Growth Factor Rev. 17 (2006) 41-58.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 41-58
    • Levy, L.1    Hill, C.S.2
  • 84
    • 33846294812 scopus 로고    scopus 로고
    • C.S. von Bartheld, H. Simon, K. Krieglstein, K. Unsicker, GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action
    • A. Schober, H. Peterziel, C.S. von Bartheld, H. Simon, K. Krieglstein, K. Unsicker, GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-beta for its neuroprotective action, Neurobiol. Dis. 25 (2007) 378-391.
    • (2007) Neurobiol. Dis. , vol.25 , pp. 378-391
    • Schober, A.1    Peterziel, H.2
  • 85
    • 0142106351 scopus 로고    scopus 로고
    • Novel functions and signalling pathways for GDNF
    • H. Sariola, M. Saarma, Novel functions and signalling pathways for GDNF, J. Cell Sci. 116 (2003) 3855-3862.
    • (2003) J. Cell Sci. , vol.116 , pp. 3855-3862
    • Sariola, H.1    Saarma, M.2
  • 86
    • 75449111153 scopus 로고    scopus 로고
    • Sciatic nerve crush evokes a biphasic TGF-beta and decorin modulation in the rat spinal cord
    • A. Kritis, D. Kapoukranidou, B. Michailidou, A. Hatzisotiriou, M. Albani, Sciatic nerve crush evokes a biphasic TGF-beta and decorin modulation in the rat spinal cord, Hippokratia 14 (2010) 37-41.
    • (2010) Hippokratia , vol.14 , pp. 37-41
    • Kritis, A.1    Kapoukranidou, D.2    Michailidou, B.3    Hatzisotiriou, A.4    Albani, M.5
  • 87
    • 0041342109 scopus 로고    scopus 로고
    • Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery
    • A.L. Mead, T.T. Wong, M.F. Cordeiro, I.K. Anderson, P.T. Khaw, Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery, Invest. Ophthalmol. Vis. Sci. 44 (2003) 3394-3401.
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 3394-3401
    • Mead, A.L.1    Wong, T.T.2    Cordeiro, M.F.3    Anderson, I.K.4    Khaw, P.T.5
  • 89
    • 10444261212 scopus 로고    scopus 로고
    • Development of TGF-beta signalling inhibitors for cancer therapy
    • J.M. Yingling, K.L. Blanchard, J.S. Sawyer, Development of TGF-beta signalling inhibitors for cancer therapy, Nat. Rev. Drug Discov. 3 (2004) 1011-1022.
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 1011-1022
    • Yingling, J.M.1    Blanchard, K.L.2    Sawyer, J.S.3
  • 90
    • 4644243836 scopus 로고    scopus 로고
    • Transforming the TGFbeta pathway: convergence of distinct lead generation strategies on a novel kinase pharmacophore for TbetaRI (ALK5)
    • J. Singh, L.E. Ling, J.S. Sawyer, W.C. Lee, F. Zhang, J.M. Yingling, Transforming the TGFbeta pathway: convergence of distinct lead generation strategies on a novel kinase pharmacophore for TbetaRI (ALK5), Curr. Opin. Drug Discov. Devel. 7 (2004) 437-445.
    • (2004) Curr. Opin. Drug Discov. Devel. , vol.7 , pp. 437-445
    • Singh, J.1    Ling, L.E.2    Sawyer, J.S.3    Lee, W.C.4    Zhang, F.5    Yingling, J.M.6
  • 93
    • 0037449750 scopus 로고    scopus 로고
    • A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression
    • F. Verrecchia, C. Tacheau, E.F. Wagner, A. Mauviel, A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression, J. Biol. Chem. 278 (2003) 1585-1593.
    • (2003) J. Biol. Chem. , vol.278 , pp. 1585-1593
    • Verrecchia, F.1    Tacheau, C.2    Wagner, E.F.3    Mauviel, A.4
  • 94
    • 0023639110 scopus 로고
    • Synergistic induction of mesoderm by FGF and TGFbeta and the identification of an mRNA coding for FGF in the early Xenopus embryo
    • D. Kimelman, M. Kirschner, Synergistic induction of mesoderm by FGF and TGFbeta and the identification of an mRNA coding for FGF in the early Xenopus embryo, Cell 51 (1987) 869-877.
    • (1987) Cell , vol.51 , pp. 869-877
    • Kimelman, D.1    Kirschner, M.2
  • 95
    • 0033961133 scopus 로고    scopus 로고
    • An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
    • L. De Moerlooze, B. Spencer-Dene, J.M. Revest, M. Hajihosseini, I. Rosewell, C. Dickson, An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis, Development 127 (2000) 483-492.
    • (2000) Development , vol.127 , pp. 483-492
    • De Moerlooze, L.1    Spencer-Dene, B.2    Revest, J.M.3    Hajihosseini, M.4    Rosewell, I.5    Dickson, C.6
  • 96
    • 0025774136 scopus 로고
    • Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos
    • E. Amaya, T.J. Musci, M.W. Kirschner, Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos, Cell 66 (1991) 257-270.
    • (1991) Cell , vol.66 , pp. 257-270
    • Amaya, E.1    Musci, T.J.2    Kirschner, M.W.3
  • 97
    • 2442675495 scopus 로고    scopus 로고
    • Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins
    • M. Koziczak, T. Holbro, N.E. Hynes, Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins, Oncogene 23 (2004) 3501-3508.
    • (2004) Oncogene , vol.23 , pp. 3501-3508
    • Koziczak, M.1    Holbro, T.2    Hynes, N.E.3
  • 101
    • 34250200790 scopus 로고    scopus 로고
    • Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas
    • M.J. Birrer, M.E. Johnson, K. Hao, K.K. Wong, D.C. Park, A. Bell, W.R. Welch, R.S. Berkowitz, S.C. Mok, Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas, J. Clin. Oncol. 25 (2007) 2281-2287.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2281-2287
    • Birrer, M.J.1    Johnson, M.E.2    Hao, K.3    Wong, K.K.4    Park, D.C.5    Bell, A.6    Welch, W.R.7    Berkowitz, R.S.8    Mok, S.C.9
  • 102
    • 0141742631 scopus 로고    scopus 로고
    • Fibroblast growth factors and their receptors in the central nervous system
    • B. Reuss, O. von Bohlen und Halbach, Fibroblast growth factors and their receptors in the central nervous system, Cell Tissue Res. 313 (2003) 139-157.
    • (2003) Cell Tissue Res , vol.313 , pp. 139-157
    • Reuss, B.1    von Bohlen und Halbach, O.2
  • 106
    • 37349105704 scopus 로고    scopus 로고
    • E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition
    • J. Matsui, Y. Yamamoto, Y. Funahashi, A. Tsuruoka, T. Watanabe, T. Wakabayashi, T. Uenaka, M. Asada, E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition, Int. J. Cancer 122 (2008) 664-671.
    • (2008) Int. J. Cancer , vol.122 , pp. 664-671
    • Matsui, J.1    Yamamoto, Y.2    Funahashi, Y.3    Tsuruoka, A.4    Watanabe, T.5    Wakabayashi, T.6    Uenaka, T.7    Asada, M.8
  • 107
    • 24344461320 scopus 로고    scopus 로고
    • Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation
    • J. Martinez-Torrecuadrada, G. Cifuentes, P. Lopez-Serra, P. Saenz, A. Martinez, J.I. Casal, Targeting the extracellular domain of fibroblast growth factor receptor 3 with human single-chain Fv antibodies inhibits bladder carcinoma cell line proliferation, Clin. Cancer Res. 11 (2005) 6280-6290.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6280-6290
    • Martinez-Torrecuadrada, J.1    Cifuentes, G.2    Lopez-Serra, P.3    Saenz, P.4    Martinez, A.5    Casal, J.I.6
  • 109
    • 0028061313 scopus 로고
    • Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord
    • T.E. Kennedy, T. Serafini, J.R. de la Torre, M. Tessier-Lavigne, Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord, Cell 78 (1994) 425-435.
    • (1994) Cell , vol.78 , pp. 425-435
    • Kennedy, T.E.1    Serafini, T.2    de la Torre, J.R.3    Tessier-Lavigne, M.4
  • 110
    • 0343081385 scopus 로고    scopus 로고
    • Semaphorins: repulsive guidance molecules show their attractive side
    • A.W. Puschel, Semaphorins: repulsive guidance molecules show their attractive side, Nat. Neurosci. 2 (1999) 777-778.
    • (1999) Nat. Neurosci. , vol.2 , pp. 777-778
    • Puschel, A.W.1
  • 111
    • 0028138219 scopus 로고
    • The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6
    • T. Serafini, T.E. Kennedy, M.J. Galko, C. Mirzayan, T.M. Jessell, M. Tessier-Lavigne, The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6, Cell 78 (1994) 409-424.
    • (1994) Cell , vol.78 , pp. 409-424
    • Serafini, T.1    Kennedy, T.E.2    Galko, M.J.3    Mirzayan, C.4    Jessell, T.M.5    Tessier-Lavigne, M.6
  • 114
    • 0032873838 scopus 로고    scopus 로고
    • Conservation and divergence of axon guidance mechanisms
    • A. Chisholm, M. Tessier-Lavigne, Conservation and divergence of axon guidance mechanisms, Curr. Opin. Neurobiol. 9 (1999) 603-615.
    • (1999) Curr. Opin. Neurobiol. , vol.9 , pp. 603-615
    • Chisholm, A.1    Tessier-Lavigne, M.2
  • 115
    • 10644221914 scopus 로고    scopus 로고
    • The versatile roles of "axon guidance" cues in tissue morphogenesis
    • L. Hinck, The versatile roles of "axon guidance" cues in tissue morphogenesis, Dev. Cell 7 (2004) 783-793.
    • (2004) Dev. Cell , vol.7 , pp. 783-793
    • Hinck, L.1
  • 116
    • 0033603256 scopus 로고    scopus 로고
    • A ligandgated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion
    • K. Hong, L. Hinck, M. Nishiyama, M.M. Poo, M. Tessier-Lavigne, E. Stein, A ligandgated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion, Cell 97 (1999) 927-941.
    • (1999) Cell , vol.97 , pp. 927-941
    • Hong, K.1    Hinck, L.2    Nishiyama, M.3    Poo, M.M.4    Tessier-Lavigne, M.5    Stein, E.6
  • 117
    • 0037531459 scopus 로고    scopus 로고
    • Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas
    • Y. Jiang, M.T. Liu, M.D. Gershon, Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas, Dev. Biol. 258 (2003) 364-384.
    • (2003) Dev. Biol. , vol.258 , pp. 364-384
    • Jiang, Y.1    Liu, M.T.2    Gershon, M.D.3
  • 120
    • 0034676061 scopus 로고    scopus 로고
    • A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization
    • M. Koch, J.R. Murrell, D.D. Hunter, P.F. Olson, W. Jin, D.R. Keene, W.J. Brunken, R.E. Burgeson, A novel member of the netrin family, beta-netrin, shares homology with the beta chain of laminin: identification, expression, and functional characterization, J. Cell Biol. 151 (2000) 221-234.
    • (2000) J. Cell Biol. , vol.151 , pp. 221-234
    • Koch, M.1    Murrell, J.R.2    Hunter, D.D.3    Olson, P.F.4    Jin, W.5    Keene, D.R.6    Brunken, W.J.7    Burgeson, R.E.8
  • 126
    • 0037345836 scopus 로고    scopus 로고
    • Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis
    • K. Srinivasan, P. Strickland, A. Valdes, G.C. Shin, L. Hinck, Netrin-1/neogenin interaction stabilizes multipotent progenitor cap cells during mammary gland morphogenesis, Dev. Cell 4 (2003) 371-382.
    • (2003) Dev. Cell , vol.4 , pp. 371-382
    • Srinivasan, K.1    Strickland, P.2    Valdes, A.3    Shin, G.C.4    Hinck, L.5
  • 128
    • 0036303033 scopus 로고    scopus 로고
    • Mechanisms and functions of Eph and ephrin signalling
    • K. Kullander, R. Klein, Mechanisms and functions of Eph and ephrin signalling, Nat. Rev. Mol. Cell Biol. 3 (2002) 475-486.
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 475-486
    • Kullander, K.1    Klein, R.2
  • 129
    • 0042591488 scopus 로고    scopus 로고
    • Axonal ephrin-As and odorant receptors: coordinate determination of the olfactory sensory map
    • T. Cutforth, L. Moring, M. Mendelsohn, A. Nemes, N.M. Shah, M.M. Kim, J. Frisen, R. Axel, Axonal ephrin-As and odorant receptors: coordinate determination of the olfactory sensory map, Cell 114 (2003) 311-322.
    • (2003) Cell , vol.114 , pp. 311-322
    • Cutforth, T.1    Moring, L.2    Mendelsohn, M.3    Nemes, A.4    Shah, N.M.5    Kim, M.M.6    Frisen, J.7    Axel, R.8
  • 130
    • 2442419137 scopus 로고    scopus 로고
    • Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application
    • B.P. Fox, R.P. Kandpal, Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application, Biochem. Biophys. Res. Commun. 318 (2004) 882-892.
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 882-892
    • Fox, B.P.1    Kandpal, R.P.2
  • 131
    • 9244264874 scopus 로고    scopus 로고
    • Receptor tyrosine kinases and inhibitors in lung cancer
    • E. Pisick, S. Jagadeesh, R. Salgia, Receptor tyrosine kinases and inhibitors in lung cancer, ScientificWorldJournal 4 (2004) 589-604.
    • (2004) ScientificWorldJournal , vol.4 , pp. 589-604
    • Pisick, E.1    Jagadeesh, S.2    Salgia, R.3
  • 134
    • 0032891292 scopus 로고    scopus 로고
    • Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines
    • K.G. Steube, C. Meyer, S. Habig, C.C. Uphoff, H.G. Drexler, Expression of receptor tyrosine kinase HTK (hepatoma transmembrane kinase) and HTK ligand by human leukemia-lymphoma cell lines, Leuk. Lymphoma 33 (1999) 371-376.
    • (1999) Leuk. Lymphoma , vol.33 , pp. 371-376
    • Steube, K.G.1    Meyer, C.2    Habig, S.3    Uphoff, C.C.4    Drexler, H.G.5
  • 135
    • 0037093097 scopus 로고    scopus 로고
    • Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior
    • K. Carles-Kinch, K.E. Kilpatrick, J.C. Stewart, M.S. Kinch, Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior, Cancer Res. 62 (2002) 2840-2847.
    • (2002) Cancer Res , vol.62 , pp. 2840-2847
    • Carles-Kinch, K.1    Kilpatrick, K.E.2    Stewart, J.C.3    Kinch, M.S.4
  • 137
    • 0037033004 scopus 로고    scopus 로고
    • An ephrin mimetic peptide that selectively targets the EphA2 receptor
    • M. Koolpe, M. Dail, E.B. Pasquale, An ephrin mimetic peptide that selectively targets the EphA2 receptor, J. Biol. Chem. 277 (2002) 46974-46979.
    • (2002) J. Biol. Chem. , vol.277 , pp. 46974-46979
    • Koolpe, M.1    Dail, M.2    Pasquale, E.B.3
  • 138
    • 0027373701 scopus 로고
    • Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones
    • Y. Luo, D. Raible, J.A. Raper, Collapsin: a protein in brain that induces the collapse and paralysis of neuronal growth cones, Cell 75 (1993) 217-227.
    • (1993) Cell , vol.75 , pp. 217-227
    • Luo, Y.1    Raible, D.2    Raper, J.A.3
  • 139
    • 53749086983 scopus 로고    scopus 로고
    • Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells
    • B. Kigel, A. Varshavsky, O. Kessler, G. Neufeld, Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells, PLoS One 3 (2008) e3287.
    • (2008) PLoS One , vol.3
    • Kigel, B.1    Varshavsky, A.2    Kessler, O.3    Neufeld, G.4
  • 140
    • 54249115942 scopus 로고    scopus 로고
    • Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells
    • E. Castro-Rivera, S. Ran, R.A. Brekken, J.D. Minna, Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells, Cancer Res. 68 (2008) 8295-8303.
    • (2008) Cancer Res , vol.68 , pp. 8295-8303
    • Castro-Rivera, E.1    Ran, S.2    Brekken, R.A.3    Minna, J.D.4
  • 143
    • 0042786843 scopus 로고    scopus 로고
    • Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury
    • J.G. Boyd, T. Gordon, Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury, Mol. Neurobiol. 27 (2003) 277-324.
    • (2003) Mol. Neurobiol. , vol.27 , pp. 277-324
    • Boyd, J.G.1    Gordon, T.2
  • 144
    • 0035204477 scopus 로고    scopus 로고
    • Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase
    • L.F. Lee, J. Guan, Y. Qiu, H.J. Kung, Neuropeptide-induced androgen independence in prostate cancer cells: roles of nonreceptor tyrosine kinases Etk/Bmx, Src, and focal adhesion kinase, Mol. Cell. Biol. 21 (2001) 8385-8397.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 8385-8397
    • Lee, L.F.1    Guan, J.2    Qiu, Y.3    Kung, H.J.4
  • 145
  • 146
    • 0037294072 scopus 로고    scopus 로고
    • Examining psychosocial factors related to cancer incidence and progression: in search of the silver lining
    • K.L. Heffner, T.J. Loving, T.F. Robles, J.K. Kiecolt-Glaser, Examining psychosocial factors related to cancer incidence and progression: in search of the silver lining, Brain Behav. Immun. 17 (Suppl 1) (2003) S109-S111.
    • (2003) Brain Behav. Immun. , vol.17 , Issue.SUPPL. 1
    • Heffner, K.L.1    Loving, T.J.2    Robles, T.F.3    Kiecolt-Glaser, J.K.4
  • 148
    • 0026536665 scopus 로고
    • The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis
    • G.P. Chrousos, P.W. Gold, The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis, JAMA 267 (1992) 1244-1252.
    • (1992) JAMA , vol.267 , pp. 1244-1252
    • Chrousos, G.P.1    Gold, P.W.2
  • 150
    • 0025744988 scopus 로고
    • Stress increases metastatic spread of a mammary tumor in rats: evidence for mediation by the immune system
    • S. Ben-Eliyahu, R. Yirmiya, J.C. Liebeskind, A.N. Taylor, R.P. Gale, Stress increases metastatic spread of a mammary tumor in rats: evidence for mediation by the immune system, Brain Behav. Immun. 5 (1991) 193-205.
    • (1991) Brain Behav. Immun. , vol.5 , pp. 193-205
    • Ben-Eliyahu, S.1    Yirmiya, R.2    Liebeskind, J.C.3    Taylor, A.N.4    Gale, R.P.5
  • 151
    • 12344326829 scopus 로고    scopus 로고
    • Marginating pulmonary-NK activity and resistance to experimental tumor metastasis: suppression by surgery and the prophylactic use of a beta-adrenergic antagonist and a prostaglandin synthesis inhibitor
    • R. Melamed, E. Rosenne, K. Shakhar, Y. Schwartz, N. Abudarham, S. Ben-Eliyahu, Marginating pulmonary-NK activity and resistance to experimental tumor metastasis: suppression by surgery and the prophylactic use of a beta-adrenergic antagonist and a prostaglandin synthesis inhibitor, Brain Behav. Immun. 19 (2005) 114-126.
    • (2005) Brain Behav. Immun. , vol.19 , pp. 114-126
    • Melamed, R.1    Rosenne, E.2    Shakhar, K.3    Schwartz, Y.4    Abudarham, N.5    Ben-Eliyahu, S.6
  • 152
    • 0035300538 scopus 로고    scopus 로고
    • Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers
    • K. Masur, B. Niggemann, K.S. Zanker, F. Entschladen, Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by beta-blockers, Cancer Res. 61 (2001) 2866-2869.
    • (2001) Cancer Res , vol.61 , pp. 2866-2869
    • Masur, K.1    Niggemann, B.2    Zanker, K.S.3    Entschladen, F.4
  • 153
    • 0030130471 scopus 로고    scopus 로고
    • Evidence for functional betaadrenoceptor subtypes in CG-5 breast cancer cell
    • G.R. Badino, A. Novelli, C. Girardi, F. Di Carlo, Evidence for functional betaadrenoceptor subtypes in CG-5 breast cancer cell, Pharmacol. Res. 33 (1996) 255-260.
    • (1996) Pharmacol. Res. , vol.33 , pp. 255-260
    • Badino, G.R.1    Novelli, A.2    Girardi, C.3    Di Carlo, F.4
  • 154
    • 0025979671 scopus 로고
    • A potential role for catecholamines in the development and progression of carcinogen-induced mammary tumors: hormonal control of beta-adrenergic receptors and correlation with tumor growth
    • B. Marchetti, P.G. Spinola, G. Pelletier, F. Labrie, A potential role for catecholamines in the development and progression of carcinogen-induced mammary tumors: hormonal control of beta-adrenergic receptors and correlation with tumor growth, J. Steroid Biochem. Mol. Biol. 38 (1991) 307-320.
    • (1991) J. Steroid Biochem. Mol. Biol. , vol.38 , pp. 307-320
    • Marchetti, B.1    Spinola, P.G.2    Pelletier, G.3    Labrie, F.4
  • 156
    • 79953223742 scopus 로고    scopus 로고
    • Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1alpha protein-dependent mechanism
    • S.Y. Park, J.H. Kang, K.J. Jeong, J. Lee, J.W. Han, W.S. Choi, Y.K. Kim, J. Kang, C.G. Park, H.Y. Lee, Norepinephrine induces VEGF expression and angiogenesis by a hypoxia-inducible factor-1alpha protein-dependent mechanism, Int. J. Cancer 128 (2011) 2306-2316.
    • (2011) Int. J. Cancer , vol.128 , pp. 2306-2316
    • Park, S.Y.1    Kang, J.H.2    Jeong, K.J.3    Lee, J.4    Han, J.W.5    Choi, W.S.6    Kim, Y.K.7    Kang, J.8    Park, C.G.9    Lee, H.Y.10
  • 157
    • 82255180781 scopus 로고    scopus 로고
    • Beta-Adrenergic Receptors (beta-AR) Regulate VEGF and IL-6 Production by Divergent Pathways in High Beta-ARExpressing Breast Cancer Cell Lines
    • K.S. Madden, M.J. Szpunar, E.B. Brown, Beta-Adrenergic Receptors (beta-AR) Regulate VEGF and IL-6 Production by Divergent Pathways in High Beta-ARExpressing Breast Cancer Cell Lines, Breast Cancer Res. Treat. (2011).
    • (2011) Breast Cancer Res. Treat.
    • Madden, K.S.1    Szpunar, M.J.2    Brown, E.B.3
  • 159
    • 67249100746 scopus 로고    scopus 로고
    • Prevention of pancreatic cancer by the beta-blocker propranolol
    • H.A. Al-Wadei, M.H. Al-Wadei, H.M. Schuller, Prevention of pancreatic cancer by the beta-blocker propranolol, Anticancer Drugs 20 (2009) 477-482.
    • (2009) Anticancer Drugs , vol.20 , pp. 477-482
    • Al-Wadei, H.A.1    Al-Wadei, M.H.2    Schuller, H.M.3
  • 160
    • 78650184684 scopus 로고    scopus 로고
    • Dopamine, by acting through its D2 receptor, inhibits insulin-like growth factor-I (IGF-I)-induced gastric cancer cell proliferation via up-regulation of Kruppel-like factor 4 through down-regulation of IGF-IR and AKT phosphorylation
    • S. Ganguly, B. Basu, S. Shome, T. Jadhav, S. Roy, J. Majumdar, P.S. Dasgupta, S. Basu, Dopamine, by acting through its D2 receptor, inhibits insulin-like growth factor-I (IGF-I)-induced gastric cancer cell proliferation via up-regulation of Kruppel-like factor 4 through down-regulation of IGF-IR and AKT phosphorylation, Am. J. Pathol. 177 (2010) 2701-2707.
    • (2010) Am. J. Pathol. , vol.177 , pp. 2701-2707
    • Ganguly, S.1    Basu, B.2    Shome, S.3    Jadhav, T.4    Roy, S.5    Majumdar, J.6    Dasgupta, P.S.7    Basu, S.8
  • 161
    • 3042734848 scopus 로고    scopus 로고
    • Depleted dopamine in gastric cancer tissues: dopamine treatment retards growth of gastric cancer by inhibiting angiogenesis
    • D. Chakroborty, C. Sarkar, R.B. Mitra, S. Banerjee, P.S. Dasgupta, S. Basu, Depleted dopamine in gastric cancer tissues: dopamine treatment retards growth of gastric cancer by inhibiting angiogenesis, Clin. Cancer Res. 10 (2004) 4349-4356.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4349-4356
    • Chakroborty, D.1    Sarkar, C.2    Mitra, R.B.3    Banerjee, S.4    Dasgupta, P.S.5    Basu, S.6
  • 162
    • 41849138680 scopus 로고    scopus 로고
    • Dopamine regulates endothelial progenitor cell mobilization from mouse bone marrow in tumor vascularization
    • D. Chakroborty, U.R. Chowdhury, C. Sarkar, R. Baral, P.S. Dasgupta, S. Basu, Dopamine regulates endothelial progenitor cell mobilization from mouse bone marrow in tumor vascularization, J. Clin. Invest. 118 (2008) 1380-1389.
    • (2008) J. Clin. Invest. , vol.118 , pp. 1380-1389
    • Chakroborty, D.1    Chowdhury, U.R.2    Sarkar, C.3    Baral, R.4    Dasgupta, P.S.5    Basu, S.6
  • 165
    • 0042130375 scopus 로고    scopus 로고
    • Are dopamine antagonists a risk factor for breast cancer? An answer from Parkinson's disease
    • F.M. Lalonde, M. Myslobodsky, Are dopamine antagonists a risk factor for breast cancer? An answer from Parkinson's disease, Breast 12 (2003) 280-282.
    • (2003) Breast , vol.12 , pp. 280-282
    • Lalonde, F.M.1    Myslobodsky, M.2
  • 166
    • 0034726953 scopus 로고    scopus 로고
    • Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation
    • M. Llovera, C. Pichard, S. Bernichtein, S. Jeay, P. Touraine, P.A. Kelly, V. Goffin, Human prolactin (hPRL) antagonists inhibit hPRL-activated signaling pathways involved in breast cancer cell proliferation, Oncogene 19 (2000) 4695-4705.
    • (2000) Oncogene , vol.19 , pp. 4695-4705
    • Llovera, M.1    Pichard, C.2    Bernichtein, S.3    Jeay, S.4    Touraine, P.5    Kelly, P.A.6    Goffin, V.7
  • 167
    • 0028963516 scopus 로고
    • Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop
    • C.V. Clevenger, W.P. Chang, W. Ngo, T.L. Pasha, K.T. Montone, J.E. Tomaszewski, Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop, Am. J. Pathol. 146 (1995) 695-705.
    • (1995) Am. J. Pathol. , vol.146 , pp. 695-705
    • Clevenger, C.V.1    Chang, W.P.2    Ngo, W.3    Pasha, T.L.4    Montone, K.T.5    Tomaszewski, J.E.6
  • 170
    • 43249113900 scopus 로고    scopus 로고
    • Role of serotonin in the hepatogastroIntestinal tract: an old molecule for new perspectives
    • M. Lesurtel, C. Soll, R. Graf, P.A. Clavien, Role of serotonin in the hepatogastroIntestinal tract: an old molecule for new perspectives, Cell. Mol. Life Sci. 65 (2008) 940-952.
    • (2008) Cell. Mol. Life Sci. , vol.65 , pp. 940-952
    • Lesurtel, M.1    Soll, C.2    Graf, R.3    Clavien, P.A.4
  • 171
    • 0028334066 scopus 로고
    • Toward a physiological approach to breast cancer prevention
    • J. Russo, I.H. Russo, Toward a physiological approach to breast cancer prevention, Cancer Epidemiol. Biomarkers Prev. 3 (1994) 353-364.
    • (1994) Cancer Epidemiol. Biomarkers Prev. , vol.3 , pp. 353-364
    • Russo, J.1    Russo, I.H.2
  • 174
    • 77954600574 scopus 로고    scopus 로고
    • Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
    • V.P. Pai, A.M. Marshall, L.L. Hernandez, A.R. Buckley, N.D. Horseman, Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival, Breast Cancer Res. 11 (2009) R81.
    • (2009) Breast Cancer Res , vol.11
    • Pai, V.P.1    Marshall, A.M.2    Hernandez, L.L.3    Buckley, A.R.4    Horseman, N.D.5
  • 176
    • 0030607663 scopus 로고    scopus 로고
    • Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells
    • L.M. Vicentini, M.G. Cattaneo, R. Fesce, Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells, Eur. J. Pharmacol. 318 (1996) 497-504.
    • (1996) Eur. J. Pharmacol. , vol.318 , pp. 497-504
    • Vicentini, L.M.1    Cattaneo, M.G.2    Fesce, R.3
  • 177
    • 33748104741 scopus 로고    scopus 로고
    • The role of serotonin (5-hydroxytryptamine1A and 1B) receptors in prostate cancer cell proliferation
    • E.J. Siddiqui, M. Shabbir, D.P. Mikhailidis, C.S. Thompson, F.H. Mumtaz, The role of serotonin (5-hydroxytryptamine1A and 1B) receptors in prostate cancer cell proliferation, J. Urol. 176 (2006) 1648-1653.
    • (2006) J. Urol. , vol.176 , pp. 1648-1653
    • Siddiqui, E.J.1    Shabbir, M.2    Mikhailidis, D.P.3    Thompson, C.S.4    Mumtaz, F.H.5
  • 179
    • 84875805905 scopus 로고    scopus 로고
    • Adjuvant and novel anti-cancer drug, keyhole limpet hemocyanin, targets serotonin signaling pathway by inhibiting feeding, locomotion and egg laying in C. elegans
    • L.G. Huggins, L.V. Davis, Adjuvant and novel anti-cancer drug, keyhole limpet hemocyanin, targets serotonin signaling pathway by inhibiting feeding, locomotion and egg laying in C. elegans, The FASEB Journal (2008) http://www.fasebj.org/cgi/content/meeting_abstract/22/1_MeetingAbstracts/748.13.
    • (2008) The FASEB Journal
    • Huggins, L.G.1    Davis, L.V.2
  • 180
    • 77956331790 scopus 로고    scopus 로고
    • Glioblastoma chemotherapy adjunct via potent serotonin receptor-7 inhibition using currently marketed high-affinity antipsychotic medicines
    • R.E. Kast, Glioblastoma chemotherapy adjunct via potent serotonin receptor-7 inhibition using currently marketed high-affinity antipsychotic medicines, Br. J. Pharmacol. 161 (2010) 481-487.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 481-487
    • Kast, R.E.1
  • 182
    • 0024417622 scopus 로고
    • Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines
    • H.M. Schuller, Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines, Biochem. Pharmacol. 38 (1989) 3439-3442.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3439-3442
    • Schuller, H.M.1
  • 183
    • 1642568706 scopus 로고    scopus 로고
    • Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway
    • S. Trombino, A. Cesario, S. Margaritora, P. Granone, G. Motta, C. Falugi, P. Russo, Alpha7-nicotinic acetylcholine receptors affect growth regulation of human mesothelioma cells: role of mitogen-activated protein kinase pathway, Cancer Res. 64 (2004) 135-145.
    • (2004) Cancer Res , vol.64 , pp. 135-145
    • Trombino, S.1    Cesario, A.2    Margaritora, S.3    Granone, P.4    Motta, G.5    Falugi, C.6    Russo, P.7
  • 184
    • 34249776345 scopus 로고    scopus 로고
    • Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholaminesynthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells
    • H.P. Wong, L. Yu, E.K. Lam, E.K. Tai, W.K. Wu, C.H. Cho, Nicotine promotes cell proliferation via alpha7-nicotinic acetylcholine receptor and catecholaminesynthesizing enzymes-mediated pathway in human colon adenocarcinoma HT-29 cells, Toxicol. Appl. Pharmacol. 221 (2007) 261-267.
    • (2007) Toxicol. Appl. Pharmacol. , vol.221 , pp. 261-267
    • Wong, H.P.1    Yu, L.2    Lam, E.K.3    Tai, E.K.4    Wu, W.K.5    Cho, C.H.6
  • 185
    • 79954871936 scopus 로고    scopus 로고
    • 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro
    • V.Y. Shin, H.C. Jin, E.K. Ng, C.H. Cho, W.K. Leung, J.J. Sung, K.M. Chu, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone promoted gastric cancer growth through prostaglandin E receptor (EP2 and EP4) in vivo and in vitro, Cancer Sci. 102 (2011) 926-33.
    • (2011) Cancer Sci , vol.102 , pp. 926-933
    • Shin, V.Y.1    Jin, H.C.2    Ng, E.K.3    Cho, C.H.4    Leung, W.K.5    Sung, J.J.6    Chu, K.M.7
  • 187
    • 0038051348 scopus 로고    scopus 로고
    • Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells
    • J.I. Ukegawa, Y. Takeuchi, S. Kusayanagi, K. Mitamura, Growth-promoting effect of muscarinic acetylcholine receptors in colon cancer cells, J. Cancer Res. Clin. Oncol. 129 (2003) 272-278.
    • (2003) J. Cancer Res. Clin. Oncol. , vol.129 , pp. 272-278
    • Ukegawa, J.I.1    Takeuchi, Y.2    Kusayanagi, S.3    Mitamura, K.4
  • 188
    • 21644452109 scopus 로고    scopus 로고
    • Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells
    • E. Jimenez, M. Montiel, Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells, J. Cell. Physiol. 204 (2005) 678-686.
    • (2005) J. Cell. Physiol. , vol.204 , pp. 678-686
    • Jimenez, E.1    Montiel, M.2
  • 189
    • 69749083891 scopus 로고    scopus 로고
    • Alpha7-nicotinic receptor antagonists at the beginning of a clinical era for NSCLC and Mesothelioma?
    • L. Paleari, A. Cesario, M. Fini, P. Russo, Alpha7-nicotinic receptor antagonists at the beginning of a clinical era for NSCLC and Mesothelioma? Drug Discov. Today 14 (2009) 822-836.
    • (2009) Drug Discov. Today , vol.14 , pp. 822-836
    • Paleari, L.1    Cesario, A.2    Fini, M.3    Russo, P.4
  • 190
    • 49149088469 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptors: new potential therapeutic targets in antinociception and in cancer therapy
    • A.M. Tata, Muscarinic acetylcholine receptors: new potential therapeutic targets in antinociception and in cancer therapy, Recent Pat. CNS Drug Discov. 3 (2008) 94-103.
    • (2008) Recent Pat. CNS Drug Discov. , vol.3 , pp. 94-103
    • Tata, A.M.1
  • 191
    • 34248597724 scopus 로고    scopus 로고
    • M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion
    • P. Song, H.S. Sekhon, A. Lu, J. Arredondo, D. Sauer, C. Gravett, G.P. Mark, S.A. Grando, E.R. Spindel, M3 muscarinic receptor antagonists inhibit small cell lung carcinoma growth and mitogen-activated protein kinase phosphorylation induced by acetylcholine secretion, Cancer Res. 67 (2007) 3936-3944.
    • (2007) Cancer Res , vol.67 , pp. 3936-3944
    • Song, P.1    Sekhon, H.S.2    Lu, A.3    Arredondo, J.4    Sauer, D.5    Gravett, C.6    Mark, G.P.7    Grando, S.A.8    Spindel, E.R.9
  • 197
    • 3042631054 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line
    • B.C. Yoo, E. Jeon, S.H. Hong, Y.K. Shin, H.J. Chang, J.G. Park, Metabotropic glutamate receptor 4-mediated 5-Fluorouracil resistance in a human colon cancer cell line, Clin. Cancer Res. 10 (2004) 4176-4184.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 4176-4184
    • Yoo, B.C.1    Jeon, E.2    Hong, S.H.3    Shin, Y.K.4    Chang, H.J.5    Park, J.G.6
  • 198
    • 18244393785 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance
    • H.J. Chang, B.C. Yoo, S.B. Lim, S.Y. Jeong, W.H. Kim, J.G. Park, Metabotropic glutamate receptor 4 expression in colorectal carcinoma and its prognostic significance, Clin. Cancer Res. 11 (2005) 3288-3295.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 3288-3295
    • Chang, H.J.1    Yoo, B.C.2    Lim, S.B.3    Jeong, S.Y.4    Kim, W.H.5    Park, J.G.6
  • 199
  • 200
    • 43149104379 scopus 로고    scopus 로고
    • Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation
    • J.F. de Groot, Y. Piao, L. Lu, G.N. Fuller, W.K. Yung, Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation, J. Neurooncol. 88 (2008) 121-133.
    • (2008) J. Neurooncol. , vol.88 , pp. 121-133
    • de Groot, J.F.1    Piao, Y.2    Lu, L.3    Fuller, G.N.4    Yung, W.K.5
  • 203
    • 29144432681 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor in human prostate cancer
    • M. Abdul, N. Hoosein, N-methyl-D-aspartate receptor in human prostate cancer, J. Membr. Biol. 205 (2005) 125-128.
    • (2005) J. Membr. Biol. , vol.205 , pp. 125-128
    • Abdul, M.1    Hoosein, N.2
  • 204
    • 39049193970 scopus 로고    scopus 로고
    • Clinical significance of metabotropic glutamate receptor 5 expression in oral squamous cell carcinoma
    • S.Y. Park, S.A. Lee, I.H. Han, B.C. Yoo, S.H. Lee, J.Y. Park, I.H. Cha, J. Kim, S.W. Choi, Clinical significance of metabotropic glutamate receptor 5 expression in oral squamous cell carcinoma, Oncol. Rep. 17 (2007) 81-87.
    • (2007) Oncol. Rep. , vol.17 , pp. 81-87
    • Park, S.Y.1    Lee, S.A.2    Han, I.H.3    Yoo, B.C.4    Lee, S.H.5    Park, J.Y.6    Cha, I.H.7    Kim, J.8    Choi, S.W.9
  • 205
    • 11144334765 scopus 로고    scopus 로고
    • Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development
    • Y.E. Marin, S. Chen, Involvement of metabotropic glutamate receptor 1, a G protein coupled receptor, in melanoma development, J. Mol. Med. 82 (2004) 735-749.
    • (2004) J. Mol. Med. , vol.82 , pp. 735-749
    • Marin, Y.E.1    Chen, S.2
  • 207
    • 4844227876 scopus 로고    scopus 로고
    • The expression of NMDA receptor 1 is associated with clinicopathological parameters and prognosis in the oral squamous cell carcinoma
    • S.W. Choi, S.Y. Park, S.P. Hong, H. Pai, J.Y. Choi, S.G. Kim, The expression of NMDA receptor 1 is associated with clinicopathological parameters and prognosis in the oral squamous cell carcinoma, J. Oral Pathol. Med. 33 (2004) 533-537.
    • (2004) J. Oral Pathol. Med. , vol.33 , pp. 533-537
    • Choi, S.W.1    Park, S.Y.2    Hong, S.P.3    Pai, H.4    Choi, J.Y.5    Kim, S.G.6
  • 209
    • 0036663012 scopus 로고    scopus 로고
    • Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans
    • M.T. Bianchi, L. Song, H. Zhang, R.L. Macdonald, Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans, J. Neurosci. 22 (2002) 5321-5327.
    • (2002) J. Neurosci. , vol.22 , pp. 5321-5327
    • Bianchi, M.T.1    Song, L.2    Zhang, H.3    Macdonald, R.L.4
  • 210
    • 0034494315 scopus 로고    scopus 로고
    • GABA(C) receptors in neuroendocrine gut cells: a new GABA-binding site in the gut
    • A. Jansen, M. Hoepfner, K.H. Herzig, E.O. Riecken, H. Scherubl, GABA(C) receptors in neuroendocrine gut cells: a new GABA-binding site in the gut, Pflugers Arch. 441 (2000) 294-300.
    • (2000) Pflugers Arch , vol.441 , pp. 294-300
    • Jansen, A.1    Hoepfner, M.2    Herzig, K.H.3    Riecken, E.O.4    Scherubl, H.5
  • 211
    • 0032144038 scopus 로고    scopus 로고
    • Expression of functional GABAA receptors in cholecystokinin-secreting gut neuroendocrine murine STC-1 cells
    • G. Glassmeier, K.H. Herzig, M. Hopfner, K. Lemmer, A. Jansen, H. Scherubl, Expression of functional GABAA receptors in cholecystokinin-secreting gut neuroendocrine murine STC-1 cells, J. Physiol. 510 (Pt 3) (1998) 805-814.
    • (1998) J. Physiol. , vol.510 , Issue.PART 3 , pp. 805-814
    • Glassmeier, G.1    Herzig, K.H.2    Hopfner, M.3    Lemmer, K.4    Jansen, A.5    Scherubl, H.6
  • 212
    • 0034144116 scopus 로고    scopus 로고
    • T lymphocytes and neutrophil granulocytes differ in regulatory signaling and migratory dynamics with regard to spontaneous locomotion and chemotaxis
    • F. Entschladen, M. Gunzer, C.M. Scheuffele, B. Niggemann, K.S. Zanker, T lymphocytes and neutrophil granulocytes differ in regulatory signaling and migratory dynamics with regard to spontaneous locomotion and chemotaxis, Cell. Immunol. 199 (2000) 104-114.
    • (2000) Cell. Immunol. , vol.199 , pp. 104-114
    • Entschladen, F.1    Gunzer, M.2    Scheuffele, C.M.3    Niggemann, B.4    Zanker, K.S.5
  • 215
    • 39049158404 scopus 로고    scopus 로고
    • GABA B receptor is a novel drug target for pancreatic cancer
    • H.M. Schuller, H.A. Al-Wadei, M. Majidi, GABA B receptor is a novel drug target for pancreatic cancer, Cancer 112 (2008) 767-778.
    • (2008) Cancer , vol.112 , pp. 767-778
    • Schuller, H.M.1    Al-Wadei, H.A.2    Majidi, M.3
  • 216
  • 218
    • 4444244390 scopus 로고    scopus 로고
    • GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation
    • M.S. Moon, E.W. Cho, H.S. Byun, I.L. Jung, I.G. Kim, GAD 67KD antisense in colon cancer cells inhibits cell growth and sensitizes to butyrate and pH reduction and H2O2 and gamma-radiation, Arch. Biochem. Biophys. 430 (2004) 229-236.
    • (2004) Arch. Biochem. Biophys. , vol.430 , pp. 229-236
    • Moon, M.S.1    Cho, E.W.2    Byun, H.S.3    Jung, I.L.4    Kim, I.G.5
  • 221
    • 27644554369 scopus 로고    scopus 로고
    • The gamma-aminobutyric acid A receptor pi subunit is overexpressed in pancreatic adenocarcinomas
    • S.K. Johnson, R.S. Haun, The gamma-aminobutyric acid A receptor pi subunit is overexpressed in pancreatic adenocarcinomas, JOP 6 (2005) 136-142.
    • (2005) JOP , vol.6 , pp. 136-142
    • Johnson, S.K.1    Haun, R.S.2
  • 222
    • 39149131369 scopus 로고    scopus 로고
    • Baclofen, a GABAB receptor agonist, inhibits human hepatocellular carcinoma cell growth in vitro and in vivo
    • T. Wang, W. Huang, F. Chen, Baclofen, a GABAB receptor agonist, inhibits human hepatocellular carcinoma cell growth in vitro and in vivo, Life Sci. 82 (2008) 536-541.
    • (2008) Life Sci , vol.82 , pp. 536-541
    • Wang, T.1    Huang, W.2    Chen, F.3
  • 223
    • 37049179817 scopus 로고
    • Early signals in the mitogenic response
    • E. Rozengurt, Early signals in the mitogenic response, Science 234 (1986) 161-166.
    • (1986) Science , vol.234 , pp. 161-166
    • Rozengurt, E.1
  • 224
    • 78651279608 scopus 로고    scopus 로고
    • Tyrosine kinase receptor transactivation associated to G protein-coupled receptors
    • V. Almendro, S. Garcia-Recio, P. Gascon, Tyrosine kinase receptor transactivation associated to G protein-coupled receptors, Curr. Drug Targets 11 (2010) 1169-1180.
    • (2010) Curr. Drug Targets , vol.11 , pp. 1169-1180
    • Almendro, V.1    Garcia-Recio, S.2    Gascon, P.3
  • 225
    • 0035952679 scopus 로고    scopus 로고
    • Autocrine and paracrine signaling through neuropeptide receptors in human cancer
    • L.E. Heasley, Autocrine and paracrine signaling through neuropeptide receptors in human cancer, Oncogene 20 (2001) 1563-1569.
    • (2001) Oncogene , vol.20 , pp. 1563-1569
    • Heasley, L.E.1
  • 226
    • 33747199597 scopus 로고    scopus 로고
    • Tachykinins and their receptors in human malignancies
    • C. Palma, Tachykinins and their receptors in human malignancies, Curr. Drug Targets 7 (2006) 1043-1052.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1043-1052
    • Palma, C.1
  • 228
    • 28644449134 scopus 로고    scopus 로고
    • Tachykinin-mediated modulation of the immune response
    • K.L. Bost, Tachykinin-mediated modulation of the immune response, Front. Biosci. 9 (2004) 3331-3332.
    • (2004) Front. Biosci. , vol.9 , pp. 3331-3332
    • Bost, K.L.1
  • 230
    • 33747451723 scopus 로고    scopus 로고
    • The expression of neurokinin-1 and preprotachykinin-1 in breast cancer cells depends on the relative degree of invasive and metastatic potential
    • T.A. Castro, M.C. Cohen, P. Rameshwar, The expression of neurokinin-1 and preprotachykinin-1 in breast cancer cells depends on the relative degree of invasive and metastatic potential, Clin. Exp. Metastasis 22 (2005) 621-628.
    • (2005) Clin. Exp. Metastasis , vol.22 , pp. 621-628
    • Castro, T.A.1    Cohen, M.C.2    Rameshwar, P.3
  • 231
    • 4344718326 scopus 로고    scopus 로고
    • Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow: a model of early cancer progression
    • G. Rao, P.S. Patel, S.P. Idler, P. Maloof, P. Gascon, J.A. Potian, P. Rameshwar, Facilitating role of preprotachykinin-I gene in the integration of breast cancer cells within the stromal compartment of the bone marrow: a model of early cancer progression, Cancer Res. 64 (2004) 2874-2881.
    • (2004) Cancer Res , vol.64 , pp. 2874-2881
    • Rao, G.1    Patel, P.S.2    Idler, S.P.3    Maloof, P.4    Gascon, P.5    Potian, J.A.6    Rameshwar, P.7
  • 232
    • 0034602721 scopus 로고    scopus 로고
    • Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis
    • D. Singh, D.D. Joshi, M. Hameed, J. Qian, P. Gascon, P.B. Maloof, A. Mosenthal, P. Rameshwar, Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis, Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 388-393.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 388-393
    • Singh, D.1    Joshi, D.D.2    Hameed, M.3    Qian, J.4    Gascon, P.5    Maloof, P.B.6    Mosenthal, A.7    Rameshwar, P.8
  • 233
    • 77954948706 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonists: a comprehensive patent survey
    • S.C. Huang, V.L. Korlipara, Neurokinin-1 receptor antagonists: a comprehensive patent survey, Expert Opin. Ther. Pat. 20 (2010) 1019-1045.
    • (2010) Expert Opin. Ther. Pat. , vol.20 , pp. 1019-1045
    • Huang, S.C.1    Korlipara, V.L.2
  • 235
    • 0030831913 scopus 로고    scopus 로고
    • Sensory neuropeptides: their role in inflammation and wound healing
    • S.D. Brain, Sensory neuropeptides: their role in inflammation and wound healing, Immunopharmacology 37 (1997) 133-152.
    • (1997) Immunopharmacology , vol.37 , pp. 133-152
    • Brain, S.D.1
  • 237
    • 16444369890 scopus 로고    scopus 로고
    • Exogenous administration of substance P enhances wound healing in a novel skin-injury model
    • A.V. Delgado, A.T. McManus, J.P. Chambers, Exogenous administration of substance P enhances wound healing in a novel skin-injury model, Exp. Biol. Med. (Maywood) 230 (2005) 271-280.
    • (2005) Exp. Biol. Med. (Maywood) , vol.230 , pp. 271-280
    • Delgado, A.V.1    McManus, A.T.2    Chambers, J.P.3
  • 238
    • 0029811783 scopus 로고    scopus 로고
    • Sensory peptides as neuromodulators of wound healing in aged rats
    • Z. Khalil, R. Helme, Sensory peptides as neuromodulators of wound healing in aged rats, J. Gerontol. A Biol. Sci. Med. Sci. 51 (1996) B354-B361.
    • (1996) J. Gerontol. A Biol. Sci. Med. Sci. , vol.51
    • Khalil, Z.1    Helme, R.2
  • 239
    • 28844445067 scopus 로고    scopus 로고
    • Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems
    • N. Zhang, J.J. Oppenheim, Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems, J. Leukoc. Biol. 78 (2005) 1210-1214.
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 1210-1214
    • Zhang, N.1    Oppenheim, J.J.2
  • 240
    • 56149111648 scopus 로고    scopus 로고
    • Targeting nerve growth factor in pain: what is the therapeutic potential?
    • J.J. Watson, S.J. Allen, D. Dawbarn, Targeting nerve growth factor in pain: what is the therapeutic potential? BioDrugs 22 (2008) 349-359.
    • (2008) BioDrugs , vol.22 , pp. 349-359
    • Watson, J.J.1    Allen, S.J.2    Dawbarn, D.3


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